Genetic Predisposition To Cancer


Genetic Predisposition To Cancer
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Genetic Predisposition To Cancer 2ed


Genetic Predisposition To Cancer 2ed
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Author : Ros Eng
language : en
Publisher: CRC Press
Release Date : 2004-08-27

Genetic Predisposition To Cancer 2ed written by Ros Eng and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-08-27 with Medical categories.


Over the last 20 years it has become increasingly apparent that the occurrence of many cancers can have an inherited basis. This book examines the principles underlying genetic predisposition to cancer and will be relevant to practising oncologists, geneticists and other professionals interested in this rapidly expanding field. Coverage is comprehensive, taking the reader from an introduction to genetic predisposition, through a discussion of the molecular biology and statistical techniques involved in the identification and characterisation of predisposition genes, to a consideration of heritable cancer syndromes, and encompasses both rare and common cancers. The text also features a discussion of cancer risk assessment, genetic counselling issues, genetic screening and cancer management options, and a consideration of the associated ethical and psychological issues. Building on the reputation of the previous edition, and to reflect the rapid advances in the field since its publication, the contents of the second edition have been thoroughly updated and include discussion of many newly identified cancer genes. In particular, the book features new chapters added on the biological basis of cancer predisposition, population-based studies of susceptibility, and evaluation of management strategies for individuals at increased cancer risk.



Genetic Predisposition To Cancer


Genetic Predisposition To Cancer
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Author : Rosalind A. Eeles
language : en
Publisher: Springer
Release Date : 2013-11-11

Genetic Predisposition To Cancer written by Rosalind A. Eeles and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-11 with Medical categories.




The Genetics Of Cancer


The Genetics Of Cancer
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Author : B.A. Ponder
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

The Genetics Of Cancer written by B.A. Ponder and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.


It has been recognized for almost 200 years that certain families seem to inherit cancer. It is only in the past decade, however, that molecular genetics and epidemiology have combined to define the role of inheritance in cancer more clearly, and to identify some of the genes involved. The causative genes can be tracked through cancer-prone families via genetic linkage and positional cloning. Several of the genes discovered have subsequently been proved to play critical roles in normal growth and development. There are also implications for the families themselves in terms of genetic testing with its attendant dilemmas, if it is not clear that useful action will result. The chapters in The Genetics of Cancer illustrate what has already been achieved and take a critical look at the future directions of this research and its potential clinical applications.



Accomplishments Collaborative Projects And Future Initiatives In Breast Cancer Genetic Predisposition


Accomplishments Collaborative Projects And Future Initiatives In Breast Cancer Genetic Predisposition
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Author : Paolo Peterlongo
language : en
Publisher: Frontiers Media SA
Release Date : 2019-10-16

Accomplishments Collaborative Projects And Future Initiatives In Breast Cancer Genetic Predisposition written by Paolo Peterlongo and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-10-16 with categories.


In this eBook, we described the accomplishments, collaborative projects and future initiatives in the field of breast cancer genetic predisposition. More specifically, the articles included focused on aspects such as mutation screening in unexplored populations, identification and characterization of novel predisposing genes and mutations, and population screening.



Genetic Predisposition To Cancer


Genetic Predisposition To Cancer
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Author : Kenneth Offit
language : en
Publisher: Clinics: Internal Medicine
Release Date : 2010

Genetic Predisposition To Cancer written by Kenneth Offit and has been published by Clinics: Internal Medicine this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010 with Medical categories.


This issue serves as a timely review of both the genetic and genomic factors resulting in a predisposition to human cancer. There is now strong evidence to support the use of genetic testing for cancer predisposition in the practice of preventive medicine, and at the same time, there is emerging new literature defining the role of genomic approaches to assessment of cancer predisposition. Articles address predisposition syndromes in the areas of breast cancer, lower GI cancer, genitourinary cancer, pediatric cancer, endocrine cancer, and hematologic malignancy.



Inherited Susceptibility To Cancer


Inherited Susceptibility To Cancer
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Author : William D. Foulkes
language : en
Publisher: Cambridge University Press
Release Date : 1998-06-28

Inherited Susceptibility To Cancer written by William D. Foulkes and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998-06-28 with Medical categories.


Many cancers, both common and rare, are known to have a hereditary predisposition and advances in genetics have clarified the risks and in some cases the mechanisms of cancer developing in an individual. First published in 1998, this important contribution to the literature of cancer genetics covers all the key issues, reviewing both the technology behind genetic risk assessment and the ethical dilemmas it poses. It is divided into two parts. The first deals with ethical, legal and social issues. The second systematically outlines current knowledge of the inheritance patterns of many different cancer types, both from a site-by-site perspective and for special groups. This authoritative volume will be of interest to oncologists, physicians and surgeons in other specialities and to health professionals in the areas of primary care, counselling and cancer risk assessment.



A Cancer In The Family


A Cancer In The Family
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Author : Theodora Ross, MD, PhD
language : en
Publisher: Penguin
Release Date : 2016-02-02

A Cancer In The Family written by Theodora Ross, MD, PhD and has been published by Penguin this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-02-02 with Health & Fitness categories.


A Kirkus Best Book of 2016 Oncologist and cancer gene hunter Theo Ross delivers the first authoritative, go-to for people facing a genetic predisposition for cancer There are 13 million people with cancer in the United States, and it’s estimated that about 1.3 million of these cases are hereditary. Yet despite advanced training in cancer genetics and years of practicing medicine, Dr. Theo Ross was never certain whether the history of cancers in her family was simple bad luck or a sign that they were carriers of a cancer-causing genetic mutation. Then she was diagnosed with melanoma, and for someone with a dark complexion, melanoma made no sense. It turned out there was a genetic factor at work. Using her own family’s story, the latest science of cancer genetics, and her experience as a practicing physician, Ross shows readers how to spot the patterns of inherited cancer, how to get tested for cancer-causing genes, and what to do if you have one. With a foreword by Siddartha Mukherjee, prize winning author of The Emperor of All Maladies, this will be the first authoritative, go-to for people facing inherited cancer, this book empowers readers to face their genetic heritage without fear and to make decisions that will keep them and their families healthy.



Selected Abstracts On Genetic Predisposition To Cancer In Man


Selected Abstracts On Genetic Predisposition To Cancer In Man
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Author : Alfred George Knudson
language : en
Publisher:
Release Date : 1980

Selected Abstracts On Genetic Predisposition To Cancer In Man written by Alfred George Knudson and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1980 with Cancer categories.




Animal Models Of Cancer Predisposition Syndromes


Animal Models Of Cancer Predisposition Syndromes
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Author : Hiroshi Hiai
language : en
Publisher: Karger Medical and Scientific Publishers
Release Date : 1999

Animal Models Of Cancer Predisposition Syndromes written by Hiroshi Hiai and has been published by Karger Medical and Scientific Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999 with Medical categories.


This book brings together some of the most recent advances made in the genetic analysis of cancer susceptibility using animal models. Leading investigators in the field present model systems for studying cancers including liver and stomach cancer, breast cancer, myeloid leukemia, retrovirus-induced lymphoma, pulmonary adenoma and familial adenomatous polyposis. An overview of transgenic and gene knockout mice is given, and in several chapters the implications of these findings for human cancers are discussed. The book is recommended reading for all scientists and graduate students in experimental cancer research and cancer genomics.



Genetic Susceptibility To Cancer


Genetic Susceptibility To Cancer
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Author : Seymour Garte
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-09

Genetic Susceptibility To Cancer written by Seymour Garte and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-09 with Medical categories.


Despite recent progress in many areas of treatment and control, cancer remains a frightening threat to everyone. While scientists have known for decades that the majority of human cancers are caused by environmental agents such as radiation and the chemicals in cigarette smoke, not everyone who smokes gets lung cancer. Furthermore, many people who assiduously avoid all possible risk from smoking, diet, and pollution still succumb to some form of cancer later in life. Does this mean that there is an element of blind chance in the underlying mechanisms of human carcinogenesis? To what extent do genetic influences play a role in determining the cancer risk of individuals? A number of `cancer families', in which several closely related individuals have suffered from various specific forms of cancer, have been studied by genetic epidemiologists. However, for the majority of cancer cases, little or no discernible genetic influence or family history is found. Recent research has discovered that for many of these `sporadic' (non-familial) cancer cases, defects or aberrations in certain metabolic genes not previously associated with genetic cancer risk may contribute to either causing the disease or at least increasing the chances of developing cancer. It is therefore possible that much of what has previously passed for `bad luck' may turn out to be a new type of `bad genes'. Genetic Susceptibility to Cancer explains that this new idea of `bad genes' may contain an unexpected positive side. The carcinogenic effects of these metabolic genes, unlike those of the oncogenes and tumor suppressor genes that are responsible for the inherited cancer syndromes, can potentially be overcome or nullified. Genetic Susceptibility to Cancer will provide a valuable reference for health professionals, researchers, clinicians and biomedical scientists who are interested in the current thinking in this critically important area of cancer management.