Genetic Predisposition To Cancer 2ed


Genetic Predisposition To Cancer 2ed
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Genetic Predisposition To Cancer 2ed


Genetic Predisposition To Cancer 2ed
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Author : Ros Eng
language : en
Publisher: CRC Press
Release Date : 2004-08-27

Genetic Predisposition To Cancer 2ed written by Ros Eng and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-08-27 with Medical categories.


Over the last 20 years it has become increasingly apparent that the occurrence of many cancers can have an inherited basis. This book examines the principles underlying genetic predisposition to cancer and will be relevant to practising oncologists, geneticists and other professionals interested in this rapidly expanding field. Coverage is comprehensive, taking the reader from an introduction to genetic predisposition, through a discussion of the molecular biology and statistical techniques involved in the identification and characterisation of predisposition genes, to a consideration of heritable cancer syndromes, and encompasses both rare and common cancers. The text also features a discussion of cancer risk assessment, genetic counselling issues, genetic screening and cancer management options, and a consideration of the associated ethical and psychological issues. Building on the reputation of the previous edition, and to reflect the rapid advances in the field since its publication, the contents of the second edition have been thoroughly updated and include discussion of many newly identified cancer genes. In particular, the book features new chapters added on the biological basis of cancer predisposition, population-based studies of susceptibility, and evaluation of management strategies for individuals at increased cancer risk.



The Genetics Of Cancer


The Genetics Of Cancer
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Author : B.A. Ponder
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

The Genetics Of Cancer written by B.A. Ponder and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.


It has been recognized for almost 200 years that certain families seem to inherit cancer. It is only in the past decade, however, that molecular genetics and epidemiology have combined to define the role of inheritance in cancer more clearly, and to identify some of the genes involved. The causative genes can be tracked through cancer-prone families via genetic linkage and positional cloning. Several of the genes discovered have subsequently been proved to play critical roles in normal growth and development. There are also implications for the families themselves in terms of genetic testing with its attendant dilemmas, if it is not clear that useful action will result. The chapters in The Genetics of Cancer illustrate what has already been achieved and take a critical look at the future directions of this research and its potential clinical applications.



Genetic Predisposition To Cancer


Genetic Predisposition To Cancer
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Author : Rosalind A. Eeles
language : en
Publisher: Springer
Release Date : 2013-11-11

Genetic Predisposition To Cancer written by Rosalind A. Eeles and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-11 with Medical categories.




Accomplishments Collaborative Projects And Future Initiatives In Breast Cancer Genetic Predisposition


Accomplishments Collaborative Projects And Future Initiatives In Breast Cancer Genetic Predisposition
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Author : Paolo Peterlongo
language : en
Publisher: Frontiers Media SA
Release Date : 2019-10-16

Accomplishments Collaborative Projects And Future Initiatives In Breast Cancer Genetic Predisposition written by Paolo Peterlongo and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-10-16 with categories.


In this eBook, we described the accomplishments, collaborative projects and future initiatives in the field of breast cancer genetic predisposition. More specifically, the articles included focused on aspects such as mutation screening in unexplored populations, identification and characterization of novel predisposing genes and mutations, and population screening.



Genetics For Health Professionals In Cancer Care


Genetics For Health Professionals In Cancer Care
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Author : Chris Jacobs
language : en
Publisher: OUP Oxford
Release Date : 2014-08-14

Genetics For Health Professionals In Cancer Care written by Chris Jacobs and has been published by OUP Oxford this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-08-14 with Medical categories.


The role of genetics is becoming increasingly important in all aspects of healthcare and particularly in the field of cancer care. Genetics for Health Professionals in Cancer Care: From Principles to Practice equips health professionals with the knowledge and skills required for all aspects of managing cancer family history. This includes taking an accurate cancer family history and drawing a family tree; understanding cancer biology, basic cancer genetics and the genes involved in hereditary breast, ovarian, prostate, colorectal, gastric and related gynaecological cancers and rare cancer predisposing syndromes; assessing cancer risk and communicating risk information; early detection and risk reducing measures available for those at increased risk and managing individuals with hereditary cancer. Drawing on experiences of health professionals, Genetics for Health Professionals in Cancer Care discusses the challenges raised and provides practical advice and insight into what happens when a patient is referred for genetic counselling and genetic testing, including the psychological, social and ethical issues faced by individuals and families with and at risk of hereditary cancer. The book also provides practical guidance on setting up a cancer family history clinic in primary and secondary care. Genetics for Health Professionals in Cancer Care is essential reading for healthcare professionals working with cancer patients and their families, and is an ideal reference text for non-specialists working in cancer genetics.



Genetic Predisposition To Cancer


Genetic Predisposition To Cancer
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Author : Kenneth Offit
language : en
Publisher: Clinics: Internal Medicine
Release Date : 2010

Genetic Predisposition To Cancer written by Kenneth Offit and has been published by Clinics: Internal Medicine this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010 with Medical categories.


This issue serves as a timely review of both the genetic and genomic factors resulting in a predisposition to human cancer. There is now strong evidence to support the use of genetic testing for cancer predisposition in the practice of preventive medicine, and at the same time, there is emerging new literature defining the role of genomic approaches to assessment of cancer predisposition. Articles address predisposition syndromes in the areas of breast cancer, lower GI cancer, genitourinary cancer, pediatric cancer, endocrine cancer, and hematologic malignancy.



A Practical Guide To Human Cancer Genetics


A Practical Guide To Human Cancer Genetics
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Author : S. V. Hodgson
language : en
Publisher: Cambridge University Press
Release Date : 1993-02-25

A Practical Guide To Human Cancer Genetics written by S. V. Hodgson and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993-02-25 with Medical categories.


This extensively up-dated and expanded edition provides the busy clinician with an essential overview of the latest developments in human cancer genetics - an area that has made significant advances since publication of the first edition. The opening section presents the principles of cancer genetics and introduces the basic concepts and mechanisms of tumorigenesis and inherited predisposition to cancer. The second part of the book provides information, on a systems basis, on the incidence, significance and management of predisposition to individual cancers. The final section then deals with specific inherited cancer syndromes, giving practical guidance on clinical investigation, screening and management of affected patients and relatives at risk. Up-to-date details of the genetic mapping of inherited cancer syndromes and the molecular genetic changes in individual cancers are also provided. Finally, an appendix provides a helpful revision guide to the fundamental principles of genetics. This practical and clear account will benefit clinicians and research workers in oncology, genetics, surgery and general medicine.



Inherited Susceptibility To Cancer


Inherited Susceptibility To Cancer
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Author : William D. Foulkes
language : en
Publisher: Cambridge University Press
Release Date : 1998-06-28

Inherited Susceptibility To Cancer written by William D. Foulkes and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998-06-28 with Medical categories.


Many cancers, both common and rare, are known to have a hereditary predisposition and advances in genetics have clarified the risks and in some cases the mechanisms of cancer developing in an individual. First published in 1998, this important contribution to the literature of cancer genetics covers all the key issues, reviewing both the technology behind genetic risk assessment and the ethical dilemmas it poses. It is divided into two parts. The first deals with ethical, legal and social issues. The second systematically outlines current knowledge of the inheritance patterns of many different cancer types, both from a site-by-site perspective and for special groups. This authoritative volume will be of interest to oncologists, physicians and surgeons in other specialities and to health professionals in the areas of primary care, counselling and cancer risk assessment.



A Practical Guide To Human Cancer Genetics


A Practical Guide To Human Cancer Genetics
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Author : Shirley V. Hodgson
language : en
Publisher: Cambridge University Press
Release Date : 1999-07-22

A Practical Guide To Human Cancer Genetics written by Shirley V. Hodgson and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999-07-22 with Medical categories.


This extensively updated and expanded edition provides the busy clinician with an essential overview of the latest developments in human cancer genetics--an area that has made significant advances since publication of the first edition. The opening section presents the principles of cancer genetics and introduces the basic concepts and mechanisms of tumorigenesis and inherited predisposition to cancer. The second part of the book provides information, on a systems basis, on the incidence, significance and management of predisposition to individual cancers. The final section deals with specific inherited cancer syndromes, giving practical guidance on clinical investigation, screening and management of affected patients and relatives at risk. The authors also provide up-to-date details of the genetic mapping of inherited cancer syndromes and the molecular genetic changes in individual cancers. Finally, an appendix provides a helpful revision guide to the fundamental principles of genetics. This practical and clear account will benefit clinicians and research workers in oncology, genetics, surgery and general medicine.



Selected Abstracts On Genetic Predisposition To Cancer In Man


Selected Abstracts On Genetic Predisposition To Cancer In Man
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Author : Alfred George Knudson
language : en
Publisher:
Release Date : 1980

Selected Abstracts On Genetic Predisposition To Cancer In Man written by Alfred George Knudson and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1980 with Cancer categories.