Genetically Modified Mosquitoes For Malaria Control
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Genetically Modified Mosquitoes For Malaria Control
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Author : Christophe Boete
language : en
Publisher: CRC Press
Release Date : 2006-07-15
Genetically Modified Mosquitoes For Malaria Control written by Christophe Boete and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-07-15 with Science categories.
Despite a century of research and attempts to control one of the deadliest foes of mankind, the malaria situation remains a major public health problem. Obviously biological explanations (the resistance of parasites and mosquitoes against available drugs and insecticides respectively) are often given, but they remain partial and incomplete. Indeed,
Ecological Aspects For Application Of Genetically Modified Mosquitoes
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Author : W. Takken
language : en
Publisher: Springer Science & Business Media
Release Date : 2003-07-31
Ecological Aspects For Application Of Genetically Modified Mosquitoes written by W. Takken and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-07-31 with Science categories.
This book is the reflection of a workshop, held in June 2002. Experts on mosquito ecology met for the first time to discuss the current knowledge of mosquito ecology with respect to GM-insect technology. Emphasis of the workshop was on evaluating how human health and natural ecosystems, including target wild-mosquito populations, will respond to the invasion of GM vectors. This volume will stimulate discussion by clearly showing the importance of vector ecology for prevention of vector-borne diseases.
Genetic Control Of Malaria And Dengue
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Author : Zach N. Adelman
language : en
Publisher: Academic Press
Release Date : 2015-10-15
Genetic Control Of Malaria And Dengue written by Zach N. Adelman and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-10-15 with Medical categories.
Genetic Control of Malaria and Dengue focuses on the knowledge, technology, regulation and ethics of using genetically modified mosquitoes to interrupt the transmission of important vector-borne diseases including Malaria. It contains coverage of the current state of knowledge of vector-borne diseases and how they are currently controlled; vaccine, drug and insecticide development; various strategies for altering the genome of mosquitoes in beneficial ways; and the regulatory, ethical and social environment concerning these strategies. For more than five decades, the prospect of using genetically-modified mosquitoes to control vector-borne disease transmission has been a purely hypothetical scenario. We simply did not have the technology or basic knowledge to be able to do it. With the explosion of field trials and potential interventions in development, Genetic Control of Malaria and Dengue provides a comprehensive overview of research in genetics, microbiology, virology, and ecology involved in the development and implementation of genetic modification programs for virus and disease control. This book is meant to provide a practical guide to researchers, regulators and the general public about how this technology actually works, how it can be improved, and what is still unknown. Includes coverage of vectorial capacity, critical to understanding vector-borne disease transmission Provides a summary of the concepts of both population suppression and population replacement Contains pivotal coverage of ethical and ecological ramifications of genetics-based control strategies
Genetically Modified And Other Innovative Vector Control Technologies
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Author : Brij Kishore Tyagi
language : en
Publisher: Springer Nature
Release Date : 2022-01-01
Genetically Modified And Other Innovative Vector Control Technologies written by Brij Kishore Tyagi and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-01 with Medical categories.
This book comprehensively covers the latest development in developing and deploying the genetically modified vectors, particularly Anopheles and Aedes mosquitoes responsible for transmitting malaria parasites and dengue viruses, the most deadly and/or debilitating among all the vector-borne diseases. It is considered timely and commensurate to bring about a book dealing with the various ecological, biological and social as well as regulatory aspects for the deployment of genetically modified vectors in special context with the biosafety of humans, his associates, and the environment. Written by an array of specialists and experts in various subjects of genetically modified organisms, this book centrally addresses the (i) basic principles of the genetic manipulation of vectors and they are potential impact on human and the environment, (ii) ecological, biological, ethical, legal and social implications of the use of genetically modified vectors, (iii) identification of potential hazards; assessment and management of risks for human and environment; risk/benefit analysis, (iv) principles and practices for the assessment and management of biosecurity and biosafety in laboratories (and in the field), (v) guiding principles for creation and management of institutional or national biosafety review boards and ethics review committees, and (vi) development and application of a biosafety regulatory framework and its related legal principles at national levels for securing the development and use of vector control methods based on genetic modification strategies. This publication will be useful to researchers, scientists, and professionals engaged in academic and research institutions, government or non-government, as well as students in universities and medical colleges.
Mosquito Gene Drives And The Malaria Eradication Agenda
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Author : Rebeca Carballar-Lejarazú
language : en
Publisher: CRC Press
Release Date : 2023-02-24
Mosquito Gene Drives And The Malaria Eradication Agenda written by Rebeca Carballar-Lejarazú and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-02-24 with Medical categories.
Malaria is one of most serious infectious diseases today and has afflicted humankind for thousands of years. A significant number of people still die from this mosquito-borne disease, despite the use of various malaria prevention and control methods over hundreds of years and more than a century of coordinated global control efforts using modern tools, together with research into and development of new strategies for prevention, diagnosis, and disease treatment. Genetic approaches that focus on the vector mosquitoes to prevent malaria parasite transmission have been considered for many decades. Genetic control strategies received a significant boost with the successful development of gene drive systems, genetic methods for rapidly spreading beneficial genes and phenotypes through mosquito populations. This book reviews some concepts of gene drive systems and describes pioneering applications to control mosquito populations and prevent parasite transmission.
Genetically Modified And Other Innovative Vector Control Technologies
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Author : Brij Kishore Tyagi
language : en
Publisher:
Release Date : 2021
Genetically Modified And Other Innovative Vector Control Technologies written by Brij Kishore Tyagi and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021 with categories.
This book comprehensively covers the latest development in developing and deploying the genetically modified vectors, particularly Anopheles and Aedes mosquitoes responsible for transmitting malaria parasites and dengue viruses, the most deadly and/or debilitating among all the vector-borne diseases. It is considered timely and commensurate to bring about a book dealing with the various ecological, biological and social as well as regulatory aspects for the deployment of genetically modified vectors in special context with the biosafety of humans, his associates, and the environment. Written by an array of specialists and experts in various subjects of genetically modified organisms, this book centrally addresses the (i) basic principles of the genetic manipulation of vectors and they are potential impact on human and the environment, (ii) ecological, biological, ethical, legal and social implications of the use of genetically modified vectors, (iii) identification of potential hazards; assessment and management of risks for human and environment; risk/benefit analysis, (iv) principles and practices for the assessment and management of biosecurity and biosafety in laboratories (and in the field), (v) guiding principles for creation and management of institutional or national biosafety review boards and ethics review committees, and (vi) development and application of a biosafety regulatory framework and its related legal principles at national levels for securing the development and use of vector control methods based on genetic modification strategies. This publication will be useful to researchers, scientists, and professionals engaged in academic and research institutions, government or non-government, as well as students in universities and medical colleges.
Evaluation Of Genetically Modified Mosquitoes For The Control Of Vector Borne Diseases
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Author :
language : en
Publisher: World Health Organization
Release Date : 2020-09-30
Evaluation Of Genetically Modified Mosquitoes For The Control Of Vector Borne Diseases written by and has been published by World Health Organization this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-09-30 with Medical categories.
Guidance Framework For Testing Genetically Modified Mosquitoes
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Author :
language : en
Publisher: World Health Organization
Release Date : 2021-05-18
Guidance Framework For Testing Genetically Modified Mosquitoes written by and has been published by World Health Organization this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-05-18 with Medical categories.
Vector Control Products Targeting Outdoor Malaria Transmission
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Author : World Health Organization
language : en
Publisher: World Health Organization
Release Date : 2023-04-05
Vector Control Products Targeting Outdoor Malaria Transmission written by World Health Organization and has been published by World Health Organization this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-04-05 with Medical categories.
Preferred product characteristics" (PPCs) are key tools to incentivize and guide the development of urgently needed health products. This PPC was developed to indicate that WHO has identified vector control products targeting outdoor malaria transmission as an unmet public health need and to outline the preferred characteristics of such interventions. While keeping the scope of the PPC as broad as possible, it is primarily tailored to encourage new insecticidal/repellent products. Endectocides/ ectocides, as well as genetically modified mosquitoes, both of which could be considered to fall into the category of interventions targeting/contributing to the reduction of outdoor malaria transmission, are already covered by a separate PPC or warrant the development of one.
The Deadly Air
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Author : Christian Jennings
language : en
Publisher: Guardian Books
Release Date :
The Deadly Air written by Christian Jennings and has been published by Guardian Books this book supported file pdf, txt, epub, kindle and other format this book has been release on with Science categories.
Hundreds of thousands of people die every year from malaria. No one’s quite sure of the exact number. It’s just too difficult to keep track of the disease as it tears through more than 200 million cases each year, many of them in countries wracked by war and blighted by other problems. What is certain is that it is people living in these situations and, more specifically, children aged under five, who suffer disproportionately. It is for these areas that universities and NGOs, drugs companies, governments and philanthropists from around the world are united in an ongoing battle against the disease. Malaria has been with us for thousands of years. The Ancient Egyptians had it; Chinese dynasties before them. One of the first treatments for the disease was quinine, brought to Europe from Peru in the mid-fifteenth century. In some arenas during the second world war, more soldiers were hospitalised by malaria than by injuries sustained during fighting. Today, malaria remains one of the most resilient and most adaptive diseases out there, constantly mutating as it finds ways around the drugs deployed to combat it. One of the key parts of the problem is the method by which malaria transmits itself from person to person: mosquito bites. Breeding, feeding and transmitting at an incredible rate, mosquitoes are unavoidable in whatever environment they live. Now, cutting edge science is being called upon to help save lives lost to malaria. By genetically modifying the mosquitoes, scientists are aiming to turn the disease’s vector against itself, severing the link that enables malaria to spread. In The Deadly Air, Christian Jennings mixes together his own experiences of suffering from malaria with a history of mankind’s struggle with the disease and an account of the scientists engaged in the modification of the mosquito’s genome. Rich in detail and scientific intrigue, The Deadly Air is the story of malaria and of the millions of lives at stake in our fight against it.