Genetics And Alzheimer S Disease
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Genetics And Alzheimer S Disease
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Author : Pierre M. Sinet
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-07
Genetics And Alzheimer S Disease written by Pierre M. Sinet and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-07 with Medical categories.
This volume contains the proceedings of the meeting Genetics and Alzheimer's Disease held in Paris, on March 25,1988, by the Fondation Ipsen pour la Recherche Therapeuti que. This meeting was the second of the series of Colloques Medecine et Recherche devoted to Alzheimer's disease. The first one was held in Angers (France) on September 14, 1987; the proceedings of this meeting have already been published and are entitled Immunology and Alzheimer's Disease (1988, edited by A Pouplard-Barthelaix, J Emile, and Y Christen). The third Colloque Medecine et Recherche, organized in Montpellier on Sep tember 19, 1988, dealt with neuronal grafting; the proceedings of this last meeting will be published in early 1989 (Neuronal Grafting and Alzheimer's Disease: Future Perspectives, edited by F Gage, A Privat and Y Christen). In each case, the Fondation Ipsen deliberately focuses attention on the most up-to-date themes, and sometimes the most controversial ones, from medical and scientific research. The genetic aspects of Alzheimer's Disease (AD) stands at the very forefront of research carried out in the last 2 years. It complements research using the formal approach, which has become possible thanks to the study of extended kindreds by J-F Foncin and other scientists. The recent work on molecular and genetics biology has followed two main pathways: 1. The study of the gene(s) responsible for the familial form(s), which can be considered the AD gene(s).
Genetic Variants In Alzheimer S Disease
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Author : Kevin Morgan
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-06-22
Genetic Variants In Alzheimer S Disease written by Kevin Morgan and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-22 with Medical categories.
Alzheimer’s Disease is the most common form of dementia. The disease is characterised by the loss of synapses and neurons in the cerebral cortex and certain subcortical regions. In the last three years, the genetics of Alzheimer’s Disease has made significant advances; in fact, one could argue more than in the previous two decades. This has resulted in the identification of nine new genes and perhaps more importantly the realization that new pathways could be involved in the pathogenesis of Alzheimer’s. These new pathways are now legitimate targets for therapeutic intervention, which can possibly lead to treatment or a possible cure. The aim of this book is to put all of the recent genetic data on these new genes into context. Different genetic variants will be discussed, as well as biomarkers and future possibilities.
Alzheimer S Disease
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Author : Sangram S. Sisodia
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-02-16
Alzheimer S Disease written by Sangram S. Sisodia and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-02-16 with Medical categories.
This book examines every major aspect of Alzheimer disease at a time when there has been no scholarly research volume on the subject published in the last 3-5 years. This edition includes expanded coverage of the cellular-level exploration of related dementing disorders, with in-depth presentation of prion diseases, Pick's disease, fronto-temporal disorders, transgenic models, and biochemistry of presenilins.
Genetic Testing For Alzheimer Disease
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Author : Stephen Garrard Post
language : en
Publisher:
Release Date : 1998
Genetic Testing For Alzheimer Disease written by Stephen Garrard Post and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998 with Family & Relationships categories.
The genetics of Alzheimer disease has been a point of intense concern and immense informational confusion for families in which a loved one is diagnosed with dementia. In recent years, however, scientists have begun to uncover the genetic bases for some forms of Alzheimer disease. Once a chromosomal defect is identified, it becomes possible to devise a test for its presence. The far-reaching implications of such tests are the focus of the present volume. In Genetic Testing for Alzheimer Disease, Stephen G. Post and Peter J. Whitehouse bring together experts from the fields of ethics, genetics, policy, neurology, philosophy, and anthropology to examine the ethical and social aspects of genetic testing for Alzheimer disease. The authors begin by focusing on current genetic findings and their clinical applicability. They then address ethical issues in genetic testing and genetic counseling for Alzheimer disease. They examine social issues such as confidentiality, discrimination, and fairness in health care. Finally, they discuss ways to educate professionals and laypeople regarding these issues. Contributors: Robert H. Binstock, Ph.D.?Thomas D. Bird, M.D. ? Robert Mullan Cook-Deegan, M.D.? Leonard Fleck, Ph.D. ? Atwood D. Gaines, Ph.D, M.P.H. ? Eric T. Juengst, Ph.D. ? Harry Karlinsky, M.D. ? Steven Miles, M.D. ? Thomas H. Murray, Ph.D. ? Stephen G. Post, Ph.D. ? Kimberly A. Quaid, Ph.D. ? Allen D. Roses, M.D. ? Greg A. Sachs, M.D. ? Peter H. St. George-Hyslop, M.D. ? Bonnie Steinbock, Ph.D. ? Arthur B. Zinn, M.D., Ph.D.
Molecular Biology Of Alzheimer S Disease
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Author : Christian Haass
language : en
Publisher: CRC Press
Release Date : 2003-09-02
Molecular Biology Of Alzheimer S Disease written by Christian Haass and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-09-02 with Science categories.
Highlighting the latest and the most timely aspects of Alzheimer's disease research, this text will enable scientists in related research fields, as well as physicians working with Alzheimer's disease patients, to obtain a quick and complete overview of the current state of the art in one of the most exciting fields in neuroscience research. Leading scientists have contributed articles focusing on key developments in this field. This includes an overview about the pathology, the genetics of familial Alzheimer's disease, proteolytic generation and aggregation of amyloid -peptide, presenilins, risk factors such as ApoE, and transgenic animal models. Some of the latest developments in Alzheimer's disease research, including the effect of presenilin knock outs on amyloid -peptide generation, are also included.
Genetics Of Alzheimer S Disease
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Author : Laura Ibanez
language : en
Publisher:
Release Date : 2022
Genetics Of Alzheimer S Disease written by Laura Ibanez and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022 with categories.
This special issue on the genetics of Alzheimer's disease was edited by Drs. Laura Ibanez and Justin Miller in 2021. It contains 10 original articles and reviews that help readers understand specific genetic contributions to Alzheimer's disease and how genetics will play a role in future Alzheimer's disease research.
Decoding Darkness
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Author : Rudolph E Tanzi
language : en
Publisher: Basic Books
Release Date : 2008-01-07
Decoding Darkness written by Rudolph E Tanzi and has been published by Basic Books this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-01-07 with Science categories.
Working from the intriguing hypothesis that Alzheimer's dementia is the result of a renegade protein-beta amyloid-Tanzi and others set out to find the gene responsible for its production. Decoding Darkness takes us deep into the minds and far-flung labs of many a prominent researcher, offering an intimate view of the high stakes of molecular genetics, the revolution that propels it, the obstacles that threaten to derail it, and the families whose lives are so dependent upon it. Tanzi and Parson ultimately reveal that Alzheimer's, like heart disease, may be effectively treated-even prevented.
Genetics Of Alzheimer S Disease
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Author : Laura Ibanez
language : en
Publisher: Mdpi AG
Release Date : 2022-01-27
Genetics Of Alzheimer S Disease written by Laura Ibanez and has been published by Mdpi AG this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-27 with Science categories.
This special issue on the genetics of Alzheimer's disease was edited by Drs. Laura Ibanez and Justin Miller in 2021. It contains 10 original articles and reviews that help readers understand specific genetic contributions to Alzheimer's disease and how genetics will play a role in future Alzheimer's disease research.
Neurodegeneration And Alzheimer S Disease
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Author : Ralph N. Martins
language : en
Publisher: John Wiley & Sons
Release Date : 2019-04-26
Neurodegeneration And Alzheimer S Disease written by Ralph N. Martins and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-04-26 with Technology & Engineering categories.
Understanding the impact of diet, exercise, genetics, and hormones on the risk and development of Alzheimer’s and other neurogenerative diseases Diet is widely known to impact on neurological function. Nevertheless, academic texts discussing this relationship are relatively few in number. This book therefore fills an important gap in the current literature. Opening with an overview of neurodegenerative diseases, particularly Alzheimer’s disease, the text then focuses on explaining the means by which glycemic control and lipid metabolism – and associated nutritional and lifestyle variables – may factor into such disorders’ prevention and treatment. An international group of experts in the fields of food science and neurodegeneration have contributed chapters that examine Alzheimer’s disease within a broad range of contexts. Offering dietary, genetic, and hormonal perspectives, the authors explore topics ranging from sugar consumption to digestive fermentation, and Alzheimer’s disease animal models to the cognition-enhancing effects of physical exercise. Also included are overviews of the latest research into current and developing methods of treatment and diagnosis, as well as differential diagnostics. This groundbreaking book: Explores how glucose metabolism, insulin resistance, lipid metabolism, and high intake of refined carbohydrates are linked to Alzheimer's disease Discusses how genetic makeup can impact risk of Alzheimer’s and Parkinson’s disease Examines cognitive changes in neurodegeneration, lists current tests for determining cognitive impairment, and provides information concerning differential diagnosis Discusses potential advantages of increasing antioxidant and micronutrient intake Reviews hormonal influences on neurodegeneration Examines the links between protein intake and Alzheimer’s disease. Neurodegeneration and Alzheimer's Disease is an essential resource for researchers, medical practitioners, dietitians, and students with an interest in neurological diseases and their diagnosis and risk factors, as well as diet-related conditions such as diabetes and obesity. Lifestyle and diet influence neurodegeneration risk, and a better understanding of this evidence amongst health professionals will hopefully lead to greater public awareness of how to reduce the likelihood of these widespread conditions.
Hannah S Heirs
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Author : Daniel A. Pollen
language : en
Publisher: Oxford University Press, USA
Release Date : 1996-09-05
Hannah S Heirs written by Daniel A. Pollen and has been published by Oxford University Press, USA this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996-09-05 with Family & Relationships categories.
In Hannah's Heirs, Dr Pollen tells the compelling story of Hannah's family and their monumental contributions to the fight against Alzheimer's disease.