Genetics And Evolution Of Aging
DOWNLOAD eBooks
Download Genetics And Evolution Of Aging PDF/ePub or read online books in Mobi eBooks. Click Download or Read Online button to get Genetics And Evolution Of Aging book now. This website allows unlimited access to, at the time of writing, more than 1.5 million titles, including hundreds of thousands of titles in various foreign languages. If the content not found or just blank you must refresh this page
Genetics And Evolution Of Aging
DOWNLOAD eBooks
Author : Michael R. Rose
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-09
Genetics And Evolution Of Aging written by Michael R. Rose and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-09 with Science categories.
Aging is one of those subjects that many biologists feel is largely unknown. Therefore, they often feel comfortable offering extremely facile generalizations that are either unsupported or directly refuted in the experimental literature. Despite this unfortunate precedent, aging is a very broad phenomenon that calls out for integration beyond the mere collecting together of results from disparate laboratory organisms. With this in mind, Part One offers several different synthetic perspectives. The editors, Rose and Finch, provide a verbal synthesis of the field that deliberately attempts to look at aging from both sides, the evolutionary and the molecular. The articles by Charlesworth and Clark both provide population genetic perspectives on aging, the former more mathematical, the latter more experimental. Bell takes a completely different approach, arguing that aging may not be the result of evolutionary forces. Bell's model instead proposes that aging could arise from the progressive deterioration of chronic host pathogen interactions. This is the first detailed publication of this model. It marks something of a return to the type of aging theories that predominated in the 1950's and 1960's, theories like the somatic mutation and error catastrophe theories. We hope that the reader will be interested by the contrast in views between the articles based on evolutionary theory and that of Bell. MR. Rose and C. E. Finch (eds. ), Genetics and Evolution of Aging, 5-12, 1994. © 1994 Kluwer Academic Publishers. The J aniform genetics of aging 2 Michael R. Rosel & Caleb E.
The Evolution Of Aging
DOWNLOAD eBooks
Author : Theodore C. Goldsmith
language : en
Publisher: Azinet
Release Date : 2006
The Evolution Of Aging written by Theodore C. Goldsmith and has been published by Azinet this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006 with Aging categories.
Goldsmith provides a historical review of biological aging theories including underlying evolution and genetics issues and describes exciting recent discoveries and new theories that are causing renewed interest in aging-by-design.
Evolutionary Biology Of Aging
DOWNLOAD eBooks
Author : Michael R. Rose
language : en
Publisher: Oxford University Press
Release Date : 1994-10-27
Evolutionary Biology Of Aging written by Michael R. Rose and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994-10-27 with Science categories.
This unique book looks at the biology of aging from a fundamentally new perspective, one based on evolutionary theory rather than traditional concepts which emphasize molecular and cellular processes. The basis for this approach lies in the fact that natural selection, as a powerful determining force, tends to decline in importance with age. Many of the characteristics we associate with aging, the author argues, are more the result of this decline than any mechanical imperative contained within organic structures. This theory in turn yields the most fruitful avenues for seeking answers to the problem of aging, and should be recognized as the intellectual core of gerontology and the foundation for future research. The author ably surveys the vast literature on aging, presenting mathematical, experimental, and comparative findings to illustrate and support the central thesis. The result is the first complete synthesis of this vital field. Evolutionary biologists, gerontologists, and all those concerned with the science of aging will find it a stimulating, strongly argued account.
Conceptual Breakthroughs In The Evolutionary Biology Of Aging
DOWNLOAD eBooks
Author : Kenneth R. Arnold
language : en
Publisher: Academic Press
Release Date : 2023-07-10
Conceptual Breakthroughs In The Evolutionary Biology Of Aging written by Kenneth R. Arnold and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-07-10 with Science categories.
Conceptual Breakthroughs in the Evolutionary Biology of Aging continues the innovative Conceptual Breakthroughs series by providing a comprehensive outline of the major breakthroughs that built the evolutionary biology of aging as a leading scientific field. Following the evolutionary study of aging from its humble origins to the present, the book's chapters treat the field’s breakthroughs one at a time. Users will find a concise and accessible analysis of the science of aging viewed through an evolutionary lens. Building upon widely-cited studies conducted by author Michael Rose, this book covers 30 subsequent years of growth and development within the field.The book highlights key publications for those who are not experts in the field, providing an important resource for researchers. Given the prevailing interest in changing the aging process dramatically, it is a powerful tool for readers who have a vested interest in understanding its causes and future control measures. Reviews cell-molecular theories of aging in the light of evolutionary biology Offers an evolutionary analysis of prospects for mitigating aging not commonly discussed within private and public sectors Provides readers with a radically different perspective on contemporary biological gerontology, specifically through the lens of evolutionary biology
Aging Is A Group Selected Adaptation
DOWNLOAD eBooks
Author : Joshua Mitteldorf
language : en
Publisher: CRC Press
Release Date : 2017-02-03
Aging Is A Group Selected Adaptation written by Joshua Mitteldorf and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-02-03 with Medical categories.
Although books exist on the evolution of aging, this is the first book written from the perspective of again as an adaptive program. It offers an insight into the implications of research on aging genetics, The author proposes the Demographic Theory of Senescence, whereby aging has been affirmatively selected because it levels the death rate over time helping stabilize population dynamics and prevent extinctions.
Mechanisms Of Life History Evolution
DOWNLOAD eBooks
Author : Thomas Flatt
language : en
Publisher: OUP Oxford
Release Date : 2011-05-12
Mechanisms Of Life History Evolution written by Thomas Flatt and has been published by OUP Oxford this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-05-12 with Science categories.
Life history theory seeks to explain the evolution of the major features of life cycles by analyzing the ecological factors that shape age-specific schedules of growth, reproduction, and survival and by investigating the trade-offs that constrain the evolution of these traits. Although life history theory has made enormous progress in explaining the diversity of life history strategies among species, it traditionally ignores the underlying proximate mechanisms. This novel book argues that many fundamental problems in life history evolution, including the nature of trade-offs, can only be fully resolved if we begin to integrate information on developmental, physiological, and genetic mechanisms into the classical life history framework. Each chapter is written by an established or up-and-coming leader in their respective field; they not only represent the state of the art but also offer fresh perspectives for future research. The text is divided into 7 sections that cover basic concepts (Part 1), the mechanisms that affect different parts of the life cycle (growth, development, and maturation; reproduction; and aging and somatic maintenance) (Parts 2-4), life history plasticity (Part 5), life history integration and trade-offs (Part 6), and concludes with a synthesis chapter written by a prominent leader in the field and an editorial postscript (Part 7).
Longevity Senescence And The Genome
DOWNLOAD eBooks
Author : Caleb E. Finch
language : en
Publisher: University of Chicago Press
Release Date : 1994-05-16
Longevity Senescence And The Genome written by Caleb E. Finch and has been published by University of Chicago Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994-05-16 with Health & Fitness categories.
Featuring extensive references, updated for this paperback edition, Longevity, Senescence, and the Genome constitutes a landmark contribution to biomedicine and the evolutionary biology of aging. To enhance gerontology's focus on human age-related dysfunctions, Caleb E. Finch provides a comparative review of all the phyla of organisms, broadening gerontology to intersect with behavioral, developmental, evolutionary, and molecular biology. By comparing species that have different developmental and life spans, Finch proposes an original typology of senescence from rapid to gradual to negligible, and he provides the first multiphyletic calculations of mortality rate constants.
Longevity Genes
DOWNLOAD eBooks
Author : Gil Atzmon, PhD
language : en
Publisher: Springer
Release Date : 2015-04-27
Longevity Genes written by Gil Atzmon, PhD and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-04-27 with Medical categories.
The release of the complete version of the human genome sequence in 2003 has paved the way for defining gene function and genetic background for phenotypic variation in humans and allowed us to study the aging process in a new light. This new volume results from that research and focuses on the genetic and epigenetic process of aging. While the interpretation of the genome data is still in its initial stages, this new volume looks at the evolving understanding of molecular mechanisms involved in cellular processes, gene function associated with complex traits, epigenetic components involve in gene control and the creation of hypothesis-free genome-wide approaches. Longevity Genes: A Blueprint for Aging explores the genetic and genomic elements that can maintain a long life such as DNA damage mechanisms, epigenetics and the way we can use this knowledge to generate customized treatments. It touches on some of the multidisciplinary approaches as well as genomic-wide association technology used to analyze complex traits. This book describes the hunt for genes affecting complex traits using a high throughput technology, with adequate consideration for the selection of an appropriate population, applications of statistical genetics and computational biology, and most importantly, considering phenotype-genotype association studies. Longevity Genes provides coverage of not only established aspects of genetics and aging, but also new approaches and perceptions in this important area of research.
The Biology Of Human Ageing
DOWNLOAD eBooks
Author : Society for the Study of Human Biology
language : en
Publisher: Cambridge University Press
Release Date : 1986-03-20
The Biology Of Human Ageing written by Society for the Study of Human Biology and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1986-03-20 with Medical categories.
This book discusses the findings of a joint symposium held in 1984 to consider human ageing and longevity from an interdisciplinary point of view.
Methuselah Flies
DOWNLOAD eBooks
Author : Hardip Brar Passananti
language : en
Publisher: World Scientific
Release Date : 2004
Methuselah Flies written by Hardip Brar Passananti and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with Music categories.
Methuselah Flies presents a trailblazing project on the biology of aging. It describes research on the first organisms to have their lifespan increased, and their aging slowed, by hereditary manipulation. These organisms are fruit flies from the species Drosophila melanogaster, the great workhorse of genetics. Michael Rose and his colleagues have been able to double the lifespan of these insects, and improved their health in numerous respects as well. The study of these flies with postponed aging is one of the best means we have of understanding, and ultimately achieving, the postponement of aging in humans. As such, the carefully presented detail of this book will be of value to research devoted to the understanding and control of aging. Methuselah Flies: is a tightly edited distillation of twenty years of work by many scientists; contains the original publications regarding the longer-lived fruit flies; offers commentaries on each of the topics covered - new, short essays that put the individual research papers in a wider context; gives full access to the original data; captures the scientific significance of postponed aging for a wide academic audience.