Genetics And Randomness
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Genetics And Randomness
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Author : Anatoly Ruvinsky
language : en
Publisher: CRC Press
Release Date : 2009-07-28
Genetics And Randomness written by Anatoly Ruvinsky and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-07-28 with Science categories.
Analyzes Randomness in Major Genetic Processes and Events No matter how far science advances, the proportion of what is knowable to what is random will remain unchanged, and attempts to ignore this critical threshold are futile at best. With the revolutionary explosion in genetic information discovery, it is crucially important to recognize the underlying limitations of scientific prediction in genetics. Genetics and Randomness furthers the understanding of the role randomness plays in critical biological processes. The book also navigates the complex nature of genetic uncertainty from different points of view and at various levels of biological organization. Avoids Unnecessary Technical Details and Specific Terminology Exploring areas ranging from basic quantum mechanics and molecular genetics to modern evolutionary genetics and the philosophy of mathematics, this well-organized text discusses: Spontaneity of mutations and their relation to subatomic randomness Deep links between subatomic fluctuations and long-term macroscopic changes in living organisms The multitude of random events that occur during development Segregation, genetic drift, and natural selection Randomness and uncertainty are not occasional and regretful deviations from the "true" principles upon which life is built. Genetics and Randomness illustrates the ubiquitous nature of randomness as an integral feature of all essential processes, effectively embracing a probabilistic understanding of the phenomena of life.
Mutation Randomness And Evolution
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Author : STOLTZFUS.
language : en
Publisher:
Release Date :
Mutation Randomness And Evolution written by STOLTZFUS. and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on with categories.
The Random Genetic Drift Fallacy
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Author : William B. Provine
language : en
Publisher: Createspace Independent Publishing Platform
Release Date : 2014
The Random Genetic Drift Fallacy written by William B. Provine and has been published by Createspace Independent Publishing Platform this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014 with Human population genetics categories.
Much of my life has been devoted to the history of population genetics. My early book was my Ph.D. thesis still in print: The Origins of Theoretical Populations Genetics (1971, 2nd edition, 1991). I stated in the 2nd edition in the Afterword that "random genetic drift" was giving me pause, as does the evolutionary synthesis. My later book was Sewall Wright and Evolutionary Biology (1986) and is also still in print. Now I am writing this book against "random genetic drift," invented by R. A. Fisher and followed by Sewall Wright and J. B. S. Haldane. "Random genetic drift" is the core of population genetics. Any person who believes in "random genetic drift" should read this book.
Advances In Genetic Statistics
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Author : Basavarajaiah D M
language : en
Publisher: Educreation Publishing
Release Date : 2017-11-25
Advances In Genetic Statistics written by Basavarajaiah D M and has been published by Educreation Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-11-25 with Education categories.
There are many books on genetic statistics and quantitative genetics. These books expect different level of preparedness and analytical interventions emphasis on the formulation of real breeding data sets. This book is not introductory, it presumes various statistical and mathematical models demonstrated and derived considering by real breeding data sets. Reader are expected to know the essential of recent statistical tools such as sensor fusion estimation techniques, Kernel regression model, mathematical modeling on hardy Weinberg equilibrium, Pham kinetic genetic model, MLE's, OLR, weighted ordinary least square analysis, genetic correlation, heritability tested by advanced statistical tools, extraction of dummy variables from genetic and non-genetic components, random mating probability models, Risk analysis of human hereditary data by Bayesian approach, algorithms of sex linked inherited X-chromosomes, evaluation of pedigree through statistical approach, sex-linked recessive disorder of human population, data reduction techniques by snap shot techniques, Kal man filter estimation of multiple genetic traits, estimation of genetic variance, structural changes of genetic parameters, oscillation of genotypic and environmental variance, linear and nonlinear models etc. The main emphasis of the entire book is derivation of mathematical and statistical models to prove hardy Weinberg equilibrium at large random mating population. The present text book describes salient objectives and practical applicability to learn what methods are available and more importantly, when they should be applied in real life .Many examples are presented to clarify the use of the recent statistical techniques and to demonstrate what conclusions can be made at the right time modeling on genetics. Nevertheless, Statistical & mathematical modeling is a diversified area including many different topics illustrated by real breeding data sets. Furthermore, an advanced statistical technique has covered in the present edition. As per the genetic model formulation, a new technology is described in all the chapters. The PG students and research Scholars will easily extend the methods to enable for the compilation of high dimensional breeding datasets (Big data) generated from different experimental designs. Although the book narrowly focuses on a few topics, each topic Genetic fundamentals is provided with the partial derivatives. In collective terms, the statistical genetics is a multidisciplinary area with rapid developments, the present text book will helps to breeder's, researcher's and students to solve the real world problems of Genetics. For example, during the time between the completion of the first draft and the publication of this book, new methodologies and model formulation may have already been developed. Therefore, the book can only focus on the principles of advance statistical genetics. The present academic book intends to be used as a textbook for post graduate students in human, plant and animal genetics, but it can also be used by researchers as a reference book. For advanced readers, they can choose to read any particular chapters as they desire.
Probabilistic Graphical Models For Genetics Genomics And Postgenomics
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Author : Christine Sinoquet
language : en
Publisher: Oxford University Press, USA
Release Date : 2014
Probabilistic Graphical Models For Genetics Genomics And Postgenomics written by Christine Sinoquet and has been published by Oxford University Press, USA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014 with Mathematics categories.
At the crossroads between statistics and machine learning, probabilistic graphical models (PGMs) provide a powerful formal framework to model complex data. An expanding volume of biological data of various types, the so-called 'omics', is in need of accurate and efficient methods for modelling and PGMs are expected to have a prominent role to play. This book provides an overview of the applications of PGMs to genetics, genomics and postgenomics to meet this increased interest.
Random Families
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Author : Rosanna Hertz
language : en
Publisher: Oxford University Press
Release Date : 2018-11-07
Random Families written by Rosanna Hertz and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-11-07 with Social Science categories.
The ready availability of donated sperm and eggs has made possible an entirely new form of family. Children of the same donor and their families, with the help of the internet, can now locate each other and make contact. Sometimes this network of families form meaningful connections that blossom into longstanding groups, and close friendships. This book is about unprecedented families that have grown up at the intersection of new reproductive technologies, social media and the human desire for belonging. Random Families asks: Do shared genes make you a family? What do couples do when they discover that their children shares half their DNA with a dozen or more other offspring from the same sperm donor? What do kids find in common with their donor siblings? What becomes of these chance networks once parents and donor siblings find one another? Based on over 350 interviews with children (ages 10-28) and their parents from all over the U.S., Random Families chronicles the chain of choices that couples and single mothers make from what donor to use to how to participate (or not) in donor sibling networks. Children reveal their understanding of a donor, the donor's spot on the family tree and the meaning of their donor siblings. Through rich first-person accounts of network membership, the book illustrates how these extraordinary relationships -- woven from bits of online information and shared genetic ties -- are transformed into new possibilities for kinship. Random Families offers down-to-earth stories from real families to highlight just how truly distinctive these contemporary new forms of family are.
Population Genetics
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Author : W.J. Ewens
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-12
Population Genetics written by W.J. Ewens and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-12 with Science categories.
Population genetics is the mathematical investigation of the changes in the genetic structure of populations brought about by selection, mutation, inbreeding, migration, and other phenomena, together with those random changes deriving from chance events. These changes are the basic components of evolutionary progress, and an understanding of their effect is therefore necessary for an informed discussion of the reasons for and nature of evolution. It would, however, be wrong to pretend that a mathematical theory, depending as it must on a large number of simplifying assump tions, should be accepted unreservedly and that its conclusions should be accepted uncritically. No-one would pretend that in the event of disagreement between observation and mathematical prediction, the discrepancy is due to anything other than the inadequacy of the mathematical treatment. The biological world is, of course, far too complex for the study of population genetics to be simply a branch of applied mathematics, so that while we are concerned here with the mathematical theory, I have tried to indicate which of our results should continue to apply in a context wider than that in which they are formally derived. The difficulties involved in the joint discussions of mathematical and genetical problems are obvious enough. I have tried to aim this book rather more at the mathematician than at the geneticist, and for this reason a brief glossary of common genetical terms is included.
An Introduction To Genetic Statistics
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Author : Oscar Kempthorne
language : en
Publisher:
Release Date : 1969
An Introduction To Genetic Statistics written by Oscar Kempthorne and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1969 with Biomathematics categories.
Stochastic Processes In Genetics And Evolution
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Author : Charles J. Mode
language : en
Publisher: World Scientific
Release Date : 2012
Stochastic Processes In Genetics And Evolution written by Charles J. Mode and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with Mathematics categories.
Prologue; Acknowledgments; Contents; 1. An Introduction to Mathematical Probability with Applications in Mendelian Genetics; 1.1 Introduction; 1.2 Mathematical Probability in Mendelian Genetics; 1.3 Examples of Finite Probability Spaces; Example 1.3.1: An Equal Frequency Model; Example 1.3.2: Partitions of an Abstract Set; Example 1.3.3: A Deterministic Case; Example 1.3.4: Inheritance of Eye Color and Sex; 1.4 Elementary Combinatorial Analysis; 1.5 The Binomial Distribution; Example 1.5.1: Distribution of Boys and Girls in Families of Size N.
Cell Biology By The Numbers
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Author : Ron Milo
language : en
Publisher: Garland Science
Release Date : 2015-12-07
Cell Biology By The Numbers written by Ron Milo and has been published by Garland Science this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-12-07 with Science categories.
A Top 25 CHOICE 2016 Title, and recipient of the CHOICE Outstanding Academic Title (OAT) Award. How much energy is released in ATP hydrolysis? How many mRNAs are in a cell? How genetically similar are two random people? What is faster, transcription or translation?Cell Biology by the Numbers explores these questions and dozens of others provid