Genitourinary Cancers Molecular Pathogenesis And Clinical Treatment
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Genitourinary Cancers Molecular Pathogenesis And Clinical Treatment
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Author : John Simmons
language : en
Publisher: Foster Academics
Release Date : 2023-09-19
Genitourinary Cancers Molecular Pathogenesis And Clinical Treatment written by John Simmons and has been published by Foster Academics this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-09-19 with Medical categories.
Genitourinary (GU) cancers refer to the cancers which occur in the urinary system and the male reproductive system. The main parts of the urinary system are urethra, kidneys, ureters and bladder. There are various types of GU cancers such as kidney cancer, bladder cancer, prostate cancer and testicular cancer. The diagnosis of these cancers can be done by performing tests such as medical imaging and biopsy. Patients of GU cancers require special care and medication. Surgery, radiation and chemotherapy are some of the major treatment options for GU cancers. This book strives to provide a fair idea about genitourinary cancers and to help develop a better understanding of the latest advances in their clinical management. It also aims to shed light on some of the unexplored aspects related to their molecular pathogenesis. A number of latest researches have been included to keep the readers up-to-date with the global concepts related to this medical condition.
Rare Genitourinary Tumors
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Author : Lance Pagliaro
language : en
Publisher: Springer
Release Date : 2016-06-28
Rare Genitourinary Tumors written by Lance Pagliaro and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-06-28 with Medical categories.
Rare Genitourinary Tumors offers the reader an up-to-date discussion of the less common neoplasms affecting the urinary tract and reproductive organs. Each authoritative chapter provides and in-depth discussion that is frequently not found in other urologic oncology textbooks. A valuable reference for urologists, oncologists, and those in specialty training, this volume provides ready access to information on etiology, incidence, risk factors, diagnosis, prognosis, insights from molecular pathology and, where applicable, data from clinical trials. The practical treatment guidelines included for each tumor type are written by experts and fully referenced.
Genomic Applications In Pathology
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Author : George Jabboure Netto
language : en
Publisher: Springer
Release Date : 2018-12-10
Genomic Applications In Pathology written by George Jabboure Netto and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-12-10 with Medical categories.
The recent advances in genomics are continuing to reshape our approach to diagnostics, prognostics and therapeutics in oncologic and other disorders. A paradigm shift in pharmacogenomics and in the diagnosis of genetic inherited diseases and infectious diseases is unfolding as the result of implementation of next generation genomic technologies. With rapidly growing knowledge and applications driving this revolution, along with significant technologic and cost changes, genomic approaches are becoming the primary methods in many laboratories and for many diseases. As a result, a plethora of clinical genomic applications have been implemented in diagnostic pathology laboratories, and the applications and demands continue to evolve rapidly. This has created a tremendous need for a comprehensive resource on genomic applications in clinical and anatomic pathology. We believe that our current textbook provides such a resource to practicing molecular pathologists, hematopathologists and other subspecialized pathologists, general pathologists, pathology and other trainees, oncologists, geneticists and a growing spectrum of other clinicians. With periodic updates and a sufficiently rapid time from submission to publication, this textbook will be the resource of choice for many professionals and teaching programs. Its focus on genomics parallels the evolution of these technologies as primary methods in the clinical lab. The rapid evolution of genomics and its applications in medicine necessitates the (frequent) updating of this publication. This text will provide a state-of-the art review of the scientific principles underlying next generation genomic technologies and the required bioinformatics approaches to analyses of the daunting amount of data generated by current and emerging genomic technologies. Implementation roadmaps for various clinical assays such as single gene, gene panels, whole exome and whole genome assays will be discussed together with issues related to reporting and the pathologist’s role in interpretation and clinical integration of genomic tests results. Genomic applications for site-specific solid tumors and hematologic neoplasms will be detailed. Genomic applications in pharmacogenomics, inherited genetic diseases and infectious diseases will also be discussed. The latest iteration of practice recommendations or guidelines in genomic testing put forth by stakeholder professional organizations such as the College of American Pathology and the Association for Molecular Pathology, will be discussed as well as regulatory issues and laboratory accreditation related to genomic testing. All chapters will be written by experts in their fields and will include the most up to date scientific and clinical information.
Neoadjuvant Immunotherapy Treatment Of Localized Genitourinary Cancers
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Author : Andrea Necchi
language : en
Publisher: Springer Nature
Release Date : 2022-01-03
Neoadjuvant Immunotherapy Treatment Of Localized Genitourinary Cancers written by Andrea Necchi and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-03 with Medical categories.
This book aims to provide readers with a current overview of enrolling trials with immune-checkpoint inhibitors in the preoperative setting of localized bladder cancer, renal cell carcinoma, and prostate cancer. The advent of immunotherapy has revolutionized treatments of genitourinary malignancy and evolved strategies for multidisciplinary management. This book explains neoadjuvant checkpoint inhibitors in localized genitourinary cancers, providing insights into the mechanisms of response and development of resistance of cancer cells to immunotherapy. It debates optimal trial design of preoperative checkpoint inhibitors in GU tumors, including optimal endpoints and the role of pathologic response as a surrogate endpoint of survival. It also illuminates clinical management of patients with organ-confined GU tumors, such as side effect management and perioperative safety, before providing an overview of biomarker use for patient selection across the early-stage GU malignancies. Lastly, the book provides the reader with the most up-to-date data emerging from clinical trials involving immunotherapy in early-stage GU malignancies. Neoadjuvant Immunotherapy Treatment of Localized Genitourinary Cancers: Multidisciplinary Management provides a comprehensive review of the field, serving as a valuable resource for urologists, medical oncologists, pathologists, fellows in urologic oncology, upper-level residents training in urology and medical oncology, as well as pharmacists interested in RCC clinicians.
Recent Advances In Pheochromocytoma And Paraganglioma Molecular Pathogenesis Clinical Impacts And Therapeutic Perspective
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Author : Farhadul Islam
language : en
Publisher: Frontiers Media SA
Release Date : 2021-10-14
Recent Advances In Pheochromocytoma And Paraganglioma Molecular Pathogenesis Clinical Impacts And Therapeutic Perspective written by Farhadul Islam and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-10-14 with Medical categories.
Practical Medical Oncology Textbook
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Author : Antonio Russo
language : en
Publisher: Springer Nature
Release Date : 2021-10-06
Practical Medical Oncology Textbook written by Antonio Russo and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-10-06 with Medical categories.
This textbook combines essential information on clinical cancer medicine with a guide to the latest advances in molecular oncology and tumor biology. Providing a systematic overview of all types of solid tumors, including epidemiology and cancer prevention, genetic aspects of hereditary cancers, differential diagnosis, typical signs and symptoms, diagnostic strategies and staging, and treatment modalities, it also discusses new and innovative cancer treatments, particularly targeted therapy and immunotherapy. Expert commentaries at the end of each chapter highlight key points, offer insights, suggest further reading and discuss clinical application using case descriptions. This textbook is an invaluable, practice-oriented tool for medical students just beginning their clinical oncology studies, as well as for medical oncology residents and young professionals.
Upper Urinary Tract Urothelial Carcinoma
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Author : Michael Grasso III
language : en
Publisher: Springer
Release Date : 2015-07-03
Upper Urinary Tract Urothelial Carcinoma written by Michael Grasso III and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-07-03 with Medical categories.
Upper Urinary Tract Urothelial Carcinoma was at one time felt to be a somewhat rare entity. With the success of various treatments for bladder urothelial carcinoma, the incidence of this disease in the uretere and kidney is rising. Many medical subspecialists encounter these complex patients and a multimodality treatment plan is often required for care.
Precision Molecular Pathology Of Bladder Cancer
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Author : Donna E. Hansel
language : en
Publisher: Springer
Release Date : 2018-01-05
Precision Molecular Pathology Of Bladder Cancer written by Donna E. Hansel and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-01-05 with Medical categories.
This succinct yet comprehensive volume describes current and emerging concepts in molecular pathology of bladder cancer. Divided into two distinct sections, the first part focuses on the general principles of molecular findings in bladder cancer, while the second part focuses on the molecular changes associated with specific histologic subtypes. The volume also addresses such topics as molecular alterations in non-invasive and invasive disease, including bladder cancer variants as appropriate, emerging molecular classifiers of bladder cancer, and molecular associations to outcome and treatment. Written by experts in the field, Precision Molecular Pathology of Bladder Cancer is a valuable resource for those in the urologic community, including urologic pathologists, urologists, urologic oncologists and radiation oncologists, who treat and manage bladder cancer.
Genitourinary Cancers
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Author : Siamak Daneshmand
language : en
Publisher: Springer
Release Date : 2018-08-31
Genitourinary Cancers written by Siamak Daneshmand and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-08-31 with Medical categories.
This book addresses the most pressing current questions in the management of urologic malignancies. The rapid advances in imaging and molecular markers are placed into a clinical context, with explanation of their effects on prognosis and treatment planning. Similarly, progress in immunotherapy is carefully examined, focusing in particular on the role of immune checkpoint inhibitors in both early- and late-stage urologic malignancies. Looking beyond the improvements in minimally invasive techniques for urologic cancers, the impacts of care coordination pathways and enhanced recovery after surgery protocols are reviewed. Readers will also find enlightening discussion of the decision algorithm for the treatment of early-stage, high-grade bladder cancer, taking into account evidence on the most advanced treatment options and the circumstances in which surgery may need to be expedited. The penultimate chapter discusses the Cancer Genome Atlas project for bladder cancer, and the book closes by considering contemporary medical and surgical management of testicular cancer.
Invasive Bladder Cancer
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Author : PierFrancesco Bassi
language : en
Publisher: Springer
Release Date : 2007-04-16
Invasive Bladder Cancer written by PierFrancesco Bassi and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-04-16 with Medical categories.
Invasive bladder tumors affect the muscle wall, and have a propensity to metastasize and spread to other areas of the body, and are more likely to be fatal. This book presents state-of-the-art diagnoses and treatments available for bladder cancer that has metastasised into the body. A thorough review of current practice is presented in a full color volume with more than 40 tables and 50 illustrations. The book offers a comprehensive review of the subject, covering epidemiology, screening, diagnostic factors, surgery, chemotherapy and post-operative monitoring. Most chapters are jointly written by a basic researcher and a clinician.