Genome Editing And Biological Weapons

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Genome Editing And Biological Weapons

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Author : Katherine Paris
language : en
Publisher: Springer Nature
Release Date : 2022-12-15

Genome Editing And Biological Weapons written by Katherine Paris and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-12-15 with Science categories.

This monograph introduces current genome editing technologies—clustered regularly interspaced short palindromic repeat (CRISPR)-CRISPR-associated (Cas) systems, transcription activator-like effector nucleases (TALENs), and zinc-finger nucleases (ZFNs)—and provides an assessment of the risk of misuse of these technologies based on the following parameters: accessibility, ease of misuse, magnitude of potential harm, and imminence of potential misuse. The findings from this assessment are applied to analyze and evaluate the threat posed by the intentional misuse of genome editing technologies to develop biological weapons. Furthermore, the book discusses the implications of misuse for different applications of genome editing, such as making existing pathogens more dangerous, modifying the human microbiome, weaponizing gene drives, engineering super soldiers, and augmenting the general population to confer economic advantages. Technologies that enable genome editing with programmable nucleases—including CRISPR, TALEN, and ZFN—allow for the precise genetic modification of organisms and cultured cells. While these technologies are used for a variety of beneficial applications, intelligence and defense experts have raised concerns that genome editing technologies, especially CRISPR, could be misused to develop new and improved biological weapons. Furthermore, experts worry that the number and type of actors who could potentially misuse genome editing is dramatically increasing given the democratization of biology, which is allowing biology to become more accessible to everyone including nonexperts. The book provides a comprehensive assessment of how feasible it is for users with different levels of knowledge and skill to acquire and then to apply the technologies to develop a biological weapon. It also provides an assessment of governability and a tailored set of recommendations that address security concerns. These recommendations are sensitive to the cost-benefit trade-off of regulating genome editing technologies. The book targets researchers as well as intelligence analysts, defense and security personnel, and policymakers.

Dictionary Of Global Bioethics

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Author : Henk ten Have
language : en
Publisher: Springer Nature
Release Date : 2021-05-26

Dictionary Of Global Bioethics written by Henk ten Have and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-05-26 with Philosophy categories.

This Dictionary presents a broad range of topics relevant in present-day global bioethics. With more than 500 entries, this dictionary covers organizations working in the field of global bioethics, international documents concerning bioethics, personalities that have played a role in the development of global bioethics, as well as specific topics in the field.The book is not only useful for students and professionals in global health activities, but can also serve as a basic tool that explains relevant ethical notions and terms. The dictionary furthers the ideals of cosmopolitanism: solidarity, equality, respect for difference and concern with what human beings- and specifically patients - have in common, regardless of their backgrounds, hometowns, religions, gender, etc. Global problems such as pandemic diseases, disasters, lack of care and medication, homelessness and displacement call for global responses.This book demonstrates that a moral vision of global health is necessary and it helps to quickly understand the basic ideas of global bioethics.

The Soviet Biological Weapons Program

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Author : Milton Leitenberg
language : en
Publisher: Harvard University Press
Release Date : 2012-07-25

The Soviet Biological Weapons Program written by Milton Leitenberg and has been published by Harvard University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-07-25 with History categories.

This is the first attempt to understand the broad scope of the USSR’s offensive biological weapons research from its inception in the 1920s. Gorbachev tried to end the program, but the US and UK never obtained clear evidence he succeeded, raising the question whether the means for waging biological warfare could be revived in Russia in the future.

A Crack In Creation

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Author : Jennifer Doudna
language : en
Publisher: Random House
Release Date : 2017-06-15

A Crack In Creation written by Jennifer Doudna and has been published by Random House this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-06-15 with Science categories.

'The most important advance of our era. One of the pioneers of the field describes the exciting hunt for the key breakthrough and what it portends for our future' Walter Isaacson World-famous scientist Jennifer Doudna - winner of the 2020 Nobel Prize in Chemistry for creating the revolutionary gene-editing technique CRISPR - explains her discovery, describes its power to reshape the future of all life and warns of its use. A handful of discoveries have changed the course of human history. This book is about the most recent and potentially the most powerful and dangerous of them all. It is an invention that allows us to rewrite the genetic code that shapes and controls all living beings. As a result, dreams of genetic manipulation have become a stark reality: the power to cure disease and alleviate suffering, as well as to re-design any species, including humans, for our own ends. Jennifer Doudna is the co-inventor of this technology - known as CRISPR - and a scientist of worldwide renown. Writing with fellow researcher Samuel Sternberg, here she provides the definitive account of her discovery, explaining how this wondrous invention works and what it is capable of. She also asks us to consider what our new-found power means: how do we enjoy its unprecedented benefits while avoiding its equally unprecedented dangers? _________________ PRAISE FOR A CRACK IN CREATION: 'The future is in our hands as never before, and this book explains the stakes like no other' George Lucas 'One of the most PIONEERING women in science . . . Exhilarating' Arianna Huffington 'Thrilling' Adam Rutherford 'An instant classic' Siddhartha Mukherjee

Biological Weapons

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Author : DR. U C Jha
language : en
Publisher: Vij Books India Pvt Ltd
Release Date : 2021-02-01

Biological Weapons written by DR. U C Jha and has been published by Vij Books India Pvt Ltd this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-02-01 with Political Science categories.

The threat of biological weapons has been worrying about the armed forces, as well as political leaders for quite some time. With the global recorded deaths from COVID-19 surpassing one million, the biotechnological revolution has heightened the fear of future weaponized pathogens. The COVID-19 virus or its variant could be the most effective weapon for future biological warfare. The indiscriminate effect of such a weapon and its power to cripple economies and devastate the lives of people may make it attractive to rogue States and non-State actors. This book provides an updated analysis of biological warfare agents, including the COVID-19 virus, biotechnological developments affecting biological agents, and the legal regime responsible for preventing the use of biological weapons.

Crispr Cas Systems

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Author : Rodolphe Barrangou
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-13

Crispr Cas Systems written by Rodolphe Barrangou and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-13 with Science categories.

CRISPR/Cas is a recently described defense system that protects bacteria and archaea against invasion by mobile genetic elements such as viruses and plasmids. A wide spectrum of distinct CRISPR/Cas systems has been identified in at least half of the available prokaryotic genomes. On-going structural and functional analyses have resulted in a far greater insight into the functions and possible applications of these systems, although many secrets remain to be discovered. In this book, experts summarize the state of the art in this exciting field.

A Strategic Vision For Biological Threat Reduction

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Author : National Academies of Sciences, Engineering, and Medicine
language : en
Publisher: National Academies Press
Release Date : 2020-05-14

A Strategic Vision For Biological Threat Reduction written by National Academies of Sciences, Engineering, and Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-05-14 with Science categories.

The National Academies of Sciences, Engineering, and Medicine was asked to articulate a 5-year strategic vision for international health security programs and provide findings and recommendations on how to optimize the impact of the Department of Defense (DOD) Biological Threat Reduction Program (BTRP) in fulfilling its biosafety and biosecurity mission. Because BTRP is just one of several U.S. government programs conducting international health security engagement, both the strategic vision and the success of the program rely on coordinating actions with the U.S. government as a whole and with its international partners. This report provides several recommendations for optimizing BTRP success in its current mission and the wider-looking strategic vision it proposes.

Preparing For Future Products Of Biotechnology

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Author : National Academies of Sciences, Engineering, and Medicine
language : en
Publisher: National Academies Press
Release Date : 2017-07-28

Preparing For Future Products Of Biotechnology written by National Academies of Sciences, Engineering, and Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-07-28 with Science categories.

Between 1973 and 2016, the ways to manipulate DNA to endow new characteristics in an organism (that is, biotechnology) have advanced, enabling the development of products that were not previously possible. What will the likely future products of biotechnology be over the next 5â€"10 years? What scientific capabilities, tools, and/or expertise may be needed by the regulatory agencies to ensure they make efficient and sound evaluations of the likely future products of biotechnology? Preparing for Future Products of Biotechnology analyzes the future landscape of biotechnology products and seeks to inform forthcoming policy making. This report identifies potential new risks and frameworks for risk assessment and areas in which the risks or lack of risks relating to the products of biotechnology are well understood.

Essentials Of Biological Security

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Author : Lijun Shang
language : en
Publisher: John Wiley & Sons
Release Date : 2024-02-23

Essentials Of Biological Security written by Lijun Shang and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-02-23 with Science categories.

Essentials of Biological Security A guide to minimizing the threat of misusing benignly intended and dual-use biological research In Essentials of Biological Security: A Global Perspective, a team of distinguished researchers delivers a fundamental resource designed to raise awareness and understanding of biological security as it pertains to the malign manipulation of benignly intended scientific research. Written by experts who have spent decades involved in biological security issues, the book is systematically organized to make it accessible to a wide range of life scientists likely to encounter dangerous opportunities for the deliberate misuse of their research. Readers will also find: A thorough introduction to biological security and the chemical and biological weapons (CBW) threat spectrum Comprehensive explorations of the history of biological weapons from antiquity to modern day Practical discussions of dual-use technologies and how to minimize their risk Expert analyses of the Biological and Toxin Weapons Convention and other relevant international agreements and organizations Perfect for professionals working in life sciences, medicine, global health, biosafety, and biosecurity, Essentials of Biological Security: A Global Perspective will also benefit anyone with an interest in and being responsible for biological security.

Insights In Biosafety Biosecurity 2022 2023 Novel Developments Current Challenges And Future Perspectives

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Author : Segaran P. Pillai
language : en
Publisher: Frontiers Media SA
Release Date : 2024-03-20

Insights In Biosafety Biosecurity 2022 2023 Novel Developments Current Challenges And Future Perspectives written by Segaran P. Pillai and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-03-20 with Science categories.

We are now entering the third decade of the 21st century, and, especially in the last years, the achievements made by scientists have been exceptional, leading to major advancements in the rapidly growing fields of bioengineering and biotechnology. This annual collection, which highlights article submissions from our Editorial Board members, looks to explore new insights, novel developments, current challenges, latest discoveries, recent advances, and future perspectives in the field of Biosafety & Biosecurity.