Genome Organization And Function In The Cell Nucleus
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Genome Organization And Function In The Cell Nucleus
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Author : Karsten Rippe
language : en
Publisher: John Wiley & Sons
Release Date : 2012-01-09
Genome Organization And Function In The Cell Nucleus written by Karsten Rippe and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-01-09 with Science categories.
By way of its clear and logical structure, as well as abundant highresolution illustrations, this is a systematic survey of the players and pathways that control genome function in the mammalian cell nucleus. As such, this handbook and reference ties together recently gained knowledge from a variety of scientific disciplines and approaches, dissecting all major genomic events: transcription, replication, repair, recombination and chromosome segregation. A special emphasis is put on transcriptional control, including genome-wide interactions and non-coding RNAs, chromatin structure, epigenetics and nuclear organization. With its focus on fundamental mechanisms and the associated biomolecules, this will remain essential reading for years to come.
Genome Organization And Function In The Cell Nucleus
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Author : Karsten Rippe
language : en
Publisher: John Wiley & Sons
Release Date : 2011-12-19
Genome Organization And Function In The Cell Nucleus written by Karsten Rippe and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-12-19 with Science categories.
By way of its clear and logical structure, as well as abundant highresolution illustrations, this is a systematic survey of the players and pathways that control genome function in the mammalian cell nucleus. As such, this handbook and reference ties together recently gained knowledge from a variety of scientific disciplines and approaches, dissecting all major genomic events: transcription, replication, repair, recombination and chromosome segregation. A special emphasis is put on transcriptional control, including genome-wide interactions and non-coding RNAs, chromatin structure, epigenetics and nuclear organization. With its focus on fundamental mechanisms and the associated biomolecules, this will remain essential reading for years to come.
Molecular Biology Of The Cell
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Author :
language : en
Publisher:
Release Date : 2004
Molecular Biology Of The Cell written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with Cells categories.
Nuclear Pore Complexes In Genome Organization Function And Maintenance
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Author : Maximiliano D’Angelo
language : en
Publisher: Springer
Release Date : 2018-02-02
Nuclear Pore Complexes In Genome Organization Function And Maintenance written by Maximiliano D’Angelo and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-02-02 with Medical categories.
The three-dimensional organization of the DNA inside the eukaryotic cell nucleus has emerged a critical regulator of genome integrity and function. Increasing evidence indicates that nuclear pore complexes (NPCs), the large protein channels that connect the nucleus to the cytoplasm, play a critical role in the establishment and maintenance of chromatin organization and in the regulation of gene activity. These findings, which oppose the traditional view of NPCs as channels with only one: the facilitation of nucleocytoplasmic molecule exchange, have completely transformed our understanding of these structures. This book describes our current knowledge of the role of NPCs in genome organization and gene expression regulation. It starts by providing an overview of the different compartments and structures of the nucleus and how they contribute to organizing the genome, then moves to examine the direct roles of NPCs and their components in gene expression regulation in different organisms, and ends by describing the function of nuclear pores in the infection and genome integration of HIV, in DNA repair and telomere maintenance, and in the regulation of chromosome segregation and mitosis. This book provides an intellectual backdrop for anyone interested in understanding how the gatekeepers of the nucleus contribute to safeguarding the integrity and function of the eukaryotic genome.
Nuclear Structure And Gene Expression
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Author : R. Curtis Bird
language : en
Publisher: Elsevier
Release Date : 1996-11-28
Nuclear Structure And Gene Expression written by R. Curtis Bird and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996-11-28 with Science categories.
Nuclear Structure and Gene Expression assimilates the contributions of genome organization and of the components of the nuclear matrix to the control of DNA and RNA synthesis. Nuclear domains which accommodate DNA replication and gene expression are considered in relation to short-term developmental and homeostatic requirements as well as to long-term commitments to phenotypic gene expression in differentiated cells. Consideration is given to the involvement of nuclear structure in gene localization as well as to the targeting and concentration of transcription factors. Aberrations in nuclear architecture associated with and potentially functionally related to pathologies are evaluated. Tumor cells are described from the perspective of the striking modifications in both the composition and organization of nuclear components. Nuclear Structure and Gene Expression presents concepts as well as experimental approaches, which define functionality of nuclear morphology.* Mechanisms of interaction between nuclear structure and genes* Gene expression regulation by elements of the nuclear matrix* How nuclear structure exerts a regulatory effect on other aspects of cell function/physiology
Advances In Enzyme Regulation
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Author : George Weber
language : en
Publisher: Elsevier
Release Date : 2006-04-03
Advances In Enzyme Regulation written by George Weber and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-04-03 with Science categories.
Volume 45 of Advances in Enzyme Regulation is the proceedings of the 45th International Synthesis in Normal and Neoplastic Tissues held at Indiana University School of Medicine Indianapolis, Indiana September 27-28, 2004. Volume 45 concentrates on subjects which have reached the stage of productive summarizaiton and critical evaluation in the light of extensive new results. This book also lives up to its goal of advancing a few steps ahead of the general front of mammalian enzymic and metabolic regulation studies. Latest information about mammalian enzymic and metabolic regulation studies Comprehensive lab resource and teaching companion International contributors from academia and industry
The Molecular Biology Of Plant Cells
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Author : H. Smith
language : en
Publisher: Univ of California Press
Release Date : 1977-01-01
The Molecular Biology Of Plant Cells written by H. Smith and has been published by Univ of California Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1977-01-01 with Science categories.
Plant cell structure and function; Gene expression and its regulation in plant cells; The manipulation of plant cells.
Cumulated Index Medicus
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Author :
language : en
Publisher:
Release Date : 1989
Cumulated Index Medicus written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1989 with Medicine categories.
Spatial Genome Organization
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Author : Karim Mekhail
language : en
Publisher: Frontiers Media SA
Release Date : 2022-02-23
Spatial Genome Organization written by Karim Mekhail and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-02-23 with Science categories.
Epigenetic Regulation And Epigenomics
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Author : Robert A. Meyers
language : en
Publisher: John Wiley & Sons
Release Date : 2012-05-29
Epigenetic Regulation And Epigenomics written by Robert A. Meyers and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-05-29 with Science categories.
Epigenetics is a term in biology referring to heritable traits that do not involve changes in the underlying DNA sequence of the organism. Epigenetic traits exist on top of or in addition to the traditional molecular basis for inheritance. The "epigenome" is a parallel to the word "genome," and refers to the overall epigenetic state of a cell. Cancer and stem cell research have gradually focused attention on these genome modifications. The molecular basis of epigenetics involves modifications to DNA and the chromatin proteins that associate with it. Methylation, for example, can silence a nearby gene and seems to be involved in some cancers. Epigenetics is beginning to form and take shape as a new scientific discipline, which will have a major impact on Medicine and essentially all fields of biology. Increasingly, researchers are unearthing links between epigenetics and a number of diseases. Although in recent years cancer has been the main focus of epigenetics, recent data suggests that epigenetic plays a critical role in psychology and psychopathology. It is being realized that normal behaviors such as maternal care and pathologies such as Schizophrenia and Alzheimer's might have an epigenetic basis. It is also becoming clear that nutrition and life experiences have epigenetic consequences. Discover more online content in the Encyclopedia of Molecular Cell Biology and Molecular Medicine.