Genome Science
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Genes In Health And Disease
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Author : Atta-ur-Rahman
language : en
Publisher: Bentham Science Publishers
Release Date : 2016-01-27
Genes In Health And Disease written by Atta-ur-Rahman and has been published by Bentham Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-01-27 with Science categories.
Genome science or genomics is essential to advancing knowledge in the fields of biology and medicine. Specifically, researchers learn about the molecular biology behind genetic expression in living organisms and related methods of treating human genetic diseases (including gene therapy). Advances in Genome Science is an e-book series which provides a multi-disciplinary view of some of the latest developments in genome research, allowing readers to capture the essence and diversity of genomics in contemporary science. The fourth volume of this ebook series features a selection of articles covering the genetic mechanisms in the development of specific plants (orchids, thale cress), Prader-Willi Syndrome, enzyme genetics (tyrosine kinase inhibitors and fungal laccases) and much more.
Human Genes And Genomes
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Author : Leon E. Rosenberg
language : en
Publisher: Academic Press
Release Date : 2012-05-18
Human Genes And Genomes written by Leon E. Rosenberg and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-05-18 with Medical categories.
In the nearly 60 years since Watson and Crick proposed the double helical structure of DNA, the molecule of heredity, waves of discoveries have made genetics the most thrilling field in the sciences. The study of genes and genomics today explores all aspects of the life with relevance in the lab, in the doctor's office, in the courtroom and even in social relationships. In this helpful guidebook, one of the most respected and accomplished human geneticists of our time communicates the importance of genes and genomics studies in all aspects of life. With the use of core concepts and the integration of extensive references, this book provides students and professionals alike with the most in-depth view of the current state of the science and its relevance across disciplines. Bridges the gap between basic human genetic understanding and one of the most promising avenues for advances in the diagnosis, prevention and treatment of human disease Includes the latest information on diagnostic testing, population screening, predicting disease susceptibility, pharmacogenomics and more Explores ethical, legal, regulatory and economic aspects of genomics in medicine Integrates historical (classical) genetics approach with the latest discoveries in structural and functional genomics
Genomics
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Author : Charles R. Cantor
language : en
Publisher: John Wiley & Sons
Release Date : 2004-01-06
Genomics written by Charles R. Cantor and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-01-06 with Science categories.
A unique exploration of the principles and methods underlying the Human Genome Project and modern molecular genetics and biotechnology-from two top researchers In Genomics, Charles R. Cantor, former director of the Human Genome Project, and Cassandra L. Smith give the first integral overview of the strategies and technologies behind the Human Genome Project and the field of molecular genetics and biotechnology. Written with a range of readers in mind-from chemists and biologists to computer scientists and engineers-the book begins with a review of the basic properties of DNA and the chromosomes that package it in cells. The authors describe the three main techniques used in DNA analysis-hybridization, polymerase chain reaction, and electrophoresis-and present a complete exploration of DNA mapping in its many different forms. By explaining both the theoretical principles and practical foundations of modern molecular genetics to a wide audience, the book brings the scientific community closer to the ultimate goal of understanding the biological function of DNA. Genomics features: * Topical organization within chapters for easy reference * A discussion of the developing methods of sequencing, such as sequencing by hybridization (SBH) in which data is read through words instead of letters * Detailed explanations and critical evaluations of the many different types of DNA maps that can be generated-including cytogenic and restriction maps as well as interspecies cell hybrids * Informed predictions for the future of DNA sequencing
Understanding The Genome
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Author : Editors of Scientific American,
language : en
Publisher: Grand Central Publishing
Release Date : 2002-06-01
Understanding The Genome written by Editors of Scientific American, and has been published by Grand Central Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-06-01 with Science categories.
Drawn from the pages of Scientific American and collected here for the first time, this work contains updated and condensed information, made accessible to a general popular science audience, on the subject of understanding the genome.
A Primer Of Genome Science
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Author : Greg Gibson
language : en
Publisher: Sinauer Associates Incorporated
Release Date : 2002
A Primer Of Genome Science written by Greg Gibson and has been published by Sinauer Associates Incorporated this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Science categories.
Genome projects: organization and objectives. Genome sequencing and annotation. gene expression and the transcriptome. Proteomics and functional genomics. SNPs variation. Integrative genomics.
Life Script
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Author : Nicholas Wade
language : en
Publisher: Simon and Schuster
Release Date : 2002-03-02
Life Script written by Nicholas Wade and has been published by Simon and Schuster this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-03-02 with Science categories.
With the decoding of the human genome, researchers can now read the script in which evolution has written the program for the design and operation of the human body. A new generation of medical treatments is at hand. Researchers are developing therapies so powerful that there is now no evident obstacle to the ancient goal of conquering most major diseases. Nicholas Wade has covered the sequencing of the genome, as well as other health and science stories, for The New York Times, in the course of which he has interviewed many of the principal researchers in the field. In this book he describes what the genome means for the health of present and future generations. Someday soon physicians will have access to DNA chips that, from a drop of blood, will screen a person's genes for all the diseases to which he or she may be genetically vulnerable. From full knowledge of the instruction manual of the human body, provided by the genome, pharmaceutical companies hope to develop a new generation of sophisticated drugs; one of the first genome-derived drugs is already undergoing clinical trials. Another vital tool will be regenerative medicine, a new kind of therapy in which new organs and tissues will be grown from a patient's own cells to replace those that are old or diseased. With the help of DNA chips, medical researchers will soon be able to diagnose diseases such as cancer much more precisely and to tailor specific treatments for each patient. Individualized medicine will also become an important part of the pharmaceutical world. Many drugs will be prescribed based on information from DNA chips that identify which of a range of drugs is best for each patient, as well as which drugs are likely to cause side effects. The medicine of the post-genomic era will be customized for a patient's genetic make-up, providing treatments based on a precise understanding of the mechanism of disease. Life Script describes a future in which good health, even perfect health, may become the standard for everyone -- at every age.
Genome Science
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Author : David Micklos
language : en
Publisher:
Release Date : 2014-01-13
Genome Science written by David Micklos and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-01-13 with Science categories.
Genome Science is a textbook and laboratory manual for advanced secondary and post-secondary education. It combines approachable narrative with extensively tested lab exercises that illustrate key concepts of genome biology in humans, invertebrates, and plants. Eighteen labs, organized into four chapters, engage students with both bioinformatics exercises and in vitro experiments. Each chapter also includes an extensive introduction that provides an historical and conceptual framework. This modular structure offers many options for enhancing existing courses, starting new courses, or supporting student research projects. The book is complete with advice for instructors, laboratory planning guidelines, recipes for solutions, and answers to student questions.
Transducing The Genome
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Author : Gary Zweiger
language : en
Publisher: McGraw Hill Professional
Release Date : 2001
Transducing The Genome written by Gary Zweiger and has been published by McGraw Hill Professional this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001 with Medical categories.
This text provides a behind-the-scenes look at the sequencing of the human genome project and the birth of the science of genomics. It explains genomics as an information science and traces its history back further than standard histories and news accounts to the early visionaries.
The Deeper Genome
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Author : John Parrington
language : en
Publisher: Oxford University Press
Release Date : 2017-10-06
The Deeper Genome written by John Parrington and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-10-06 with Science categories.
Over a decade ago, as the Human Genome Project completed its mapping of the entire human genome, hopes ran high that we would rapidly be able to use our knowledge of human genes to tackle many inherited diseases, and understand what makes us unique among animals. But things didn't turn out that way. For a start, we turned out to have far fewer genes than originally thought — just over 20,000, the same sort of number as a fruit fly or worm. What's more, the proportion of DNA consisting of genes coding for proteins was a mere 2%. So, was the rest of the genome accumulated 'junk'? Things have changed since those early heady days of the Human Genome Project. But the emerging picture is if anything far more exciting. In this book, John Parrington explains the key features that are coming to light - some, such as the results of the international ENCODE programme, still much debated and controversial in their scope. He gives an outline of the deeper genome, involving layers of regulatory elements controlling and coordinating the switching on and off of genes; the impact of its 3D geometry; the discovery of a variety of new RNAs playing critical roles; the epigenetic changes influenced by the environment and life experiences that can make identical twins different and be passed on to the next generation; and the clues coming out of comparisons with the genomes of Neanderthals as well as that of chimps about the development of our species. We are learning more about ourselves, and about the genetic aspects of many diseases. But in its complexity, flexibility, and ability to respond to environmental cues, the human genome is proving to be far more subtle than we ever imagined.
Genes And Genomes
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Author : Maxine Singer
language : en
Publisher: University Science Books
Release Date : 1991
Genes And Genomes written by Maxine Singer and has been published by University Science Books this book supported file pdf, txt, epub, kindle and other format this book has been release on 1991 with Medical categories.
The celebrated authors present an in-depth overview of the molecular structures and mechanisms that underlie the utilization of genetic information by complex organisms. They emphasize the experimental aspects of molecular genetics, offering a complete introduction to both principles and methods. "Excellent, suitably detailed and superbly written." Philip Leder, Harvard Medical School