Genomic Imprinting
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Genomic Imprinting
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Author : R. Ohlsson
language : en
Publisher: Cambridge University Press
Release Date : 1995-12-14
Genomic Imprinting written by R. Ohlsson and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995-12-14 with Medical categories.
This significant new publication on genomic or parental imprinting has been prepared by an outstanding team of international authorities. Genomic imprinting results in the preferential expression of one allele, depending on the parent of origin. It is associated with several disease syndromes in humans. Interest in this area has expanded rapidly from the time when it was first recognised that some important hereditary characterisitics were not adequately explained by the Mendelian laws of inheritance. The chapters cover a wealth of material to help explain not only the mechanisms of genomic imprinting but its biological and medical consequences.
Genomic Imprinting
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Author : Jon F. Wilkins
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-10-01
Genomic Imprinting written by Jon F. Wilkins and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-10-01 with Medical categories.
The goal of this book is neither to provide a basic introduction to imprinting, nor to provide a comprehensive survey of the current state of the field. Rather, the book covers more recent advances, drawing attention to the emerging subtleties and complexities associated with imprinted genes. Genomic imprinting refers to a recently discovered phenomenon in which the expression pattern of an allele depends on whether that allele was inherited from the mother or the father.
Genomic Imprinting
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Author : Andrew Ward
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-02-02
Genomic Imprinting written by Andrew Ward and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-02-02 with Medical categories.
Genomic imprinting is the process by which gene activity is regulated according to parent of origin. Usually, this means that either the maternally inherited or the paternally inherited allele of a gene is expressed while the opposite allele is repressed. The phenomenon is largely restricted to mammals and flowering plants and was first recognized at the level of whole genomes. Nuclear transplantation experiments carried out in mice in the late 1970s established the non-equivalence of the maternal and paternal genomes in mammals, and a similar conclusion was drawn from studies of interploidy crosses of flowering plants that extend back to at least the 1930s. Further mouse genetic studies, involving animals carrying balanced translocations (reviewed in Chapter 3), indicated that imprinted genes were likely to be widely scattered and would form a minority within the mammalian genome. The first imprinted genes were identified in the early 1990s; over forty are now known in mammals and the list continues steadily to expand.
Genomic Imprinting And Kinship
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Author : David Haig
language : en
Publisher: Rutgers University Press
Release Date : 2002
Genomic Imprinting And Kinship written by David Haig and has been published by Rutgers University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Science categories.
Genomic imprinting allows scientists to trace genes to the parent of origin. This volume presents a collection of 13 papers by David Haig (organisimic and evolutionary biology, Harvard U.) on genomic imprinting. He argues that our paternally and maternally active genes do not work in cooperation with each other and in fact are in competition. Each paper is followed by commentary by the author, providing background information and discussing developments since its publication. Annotation copyrighted by Book News Inc., Portland, OR.
Genomic Imprinting
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Author : Rolf Ohlsson
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-06-29
Genomic Imprinting written by Rolf Ohlsson and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-29 with Science categories.
The form and function of every living organism on the earth depends on the complex regulation of gene expression. This is carried out by controlling and interdigitating spatial and temporal patterns of gene activity during the life time of eukaryotic organisms. This is most dramatically apparent during early stages of development, when new types of cells and organs are being formed, often during very short time spans. To achieve this, it is vital that developmentally important genes can be kept in inactive or active states which are stably inherited in the soma. Indeed, it is now wellknown that the propen sity for a gene to be transcribed or silenced is stably propagated through many cell generations, even from parent to progeny. This phenomenon constitutes a type of extragenetic or epigenetic memory of cell identity and developmental potential which has been fundamental to the evolution of complex lifeforms, such as the reader of this book. This monograph focuses on a particular aspect of the epigenetic control of gene function: genomic imprinting. This defines a phenomenon where some genes or whole chromosomes can be silenced, activated, or even deleted depending on their parental origin. The impact of genomic imprinting is most clearly seen in the areas of cancer, clinical genetics, and development. Many of the processes associated with genomic imprinting can be observed in plants, yeast and man, for example, and may constitute, therefore, principles which are very conserved on an evolutionary scale.
Genomic Imprinting And Uniparental Disomy In Medicine
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Author : Eric Engel
language : en
Publisher: John Wiley & Sons
Release Date : 2004-03-24
Genomic Imprinting And Uniparental Disomy In Medicine written by Eric Engel and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-03-24 with Medical categories.
Eric Engel and Stylianos Antonarakis have written the most authoritative and vital reference on molecular and clinical aspects of uniparental disomy (UPD) and genomic imprinting to date. Genomic Imprinting and Uniparental Disomy in Medicine features comprehensive overviews of a multitude of genetic disorders linked to UPD, with a strong emphasis on clinical consequences. This book will provide readers with the tools necessary to identify and treat diseases associated with nontraditional chromosomal inheritance. Genomic Imprinting and Uniparental Disomy in Medicine features handy tables summarizing clinical phenotypes and chromosomal involvement in UPD, as well as clear illustrations on imprinting mechanisms and diagnostic testing. This authoritative, completely up-to-date practical reference will be useful for any clinical geneticist, genetic counselor, physician, or researcher encountering patients with such disorders or studying complex disease mechanisms.
Genomic Imprinting
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Author : British Society for Developmental Biology
language : en
Publisher:
Release Date : 1990
Genomic Imprinting written by British Society for Developmental Biology and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1990 with Chromosome abnormalities categories.
Epigenetics
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Author : Derek J. Chadwick
language : en
Publisher: John Wiley & Sons
Release Date : 2008-04-30
Epigenetics written by Derek J. Chadwick and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-04-30 with Science categories.
Epigenetics pertains to the development of an organism from an undifferential cell, resulting in the successive formation and development of organs and parts that did not pre-exist in the fertilized egg. An exciting and stimulating volume which used the extensive knowledge of basic transcriptional control as a foundation to explore the more complex and interesting level at which genes can be regulated.
Epigenetics How Environment Shapes Our Genes
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Author : Richard C. Francis
language : en
Publisher: W. W. Norton & Company
Release Date : 2011-06-13
Epigenetics How Environment Shapes Our Genes written by Richard C. Francis and has been published by W. W. Norton & Company this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-06-13 with Science categories.
Goodbye, genetic blueprint. . . . The first book for general readers on the game-changing field of epigenetics. The burgeoning new science of epigenetics offers a cornucopia of insights—some comforting, some frightening. For example, the male fetus may be especially vulnerable to certain common chemicals in our environment, in ways that damage not only his own sperm but also the sperm of his sons. And it’s epigenetics that causes identical twins to vary widely in their susceptibility to dementia and cancer. But here’s the good news: unlike mutations, epigenetic effects are reversible. Indeed, epigenetic engineering is the future of medicine.
Evolutionary Analyses Of Genomic Imprinting And Other Regarding Motivations
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Author : Jeremy Van Cleve
language : en
Publisher:
Release Date : 2009
Evolutionary Analyses Of Genomic Imprinting And Other Regarding Motivations written by Jeremy Van Cleve and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009 with categories.