Globally Resilient Supply Chains For Seasonal And Pandemic Influenza Vaccines
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Globally Resilient Supply Chains For Seasonal And Pandemic Influenza Vaccines
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Author : National Academy of Medicine
language : en
Publisher: National Academies Press
Release Date : 2021-12-31
Globally Resilient Supply Chains For Seasonal And Pandemic Influenza Vaccines written by National Academy of Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-12-31 with Medical categories.
Influenza viruses, both seasonal and pandemic, have the potential to disrupt the health and well-being of populations around the world. The global response to the COVID-19 pandemic and prior public health emergencies of international concern illustrate the importance of global preparedness and coordination among governments, academia, scientists, policy makers, nongovernmental organizations, the private sector, and the public to address the threat of pandemic influenza. These health emergencies have revealed opportunities to enhance global vaccine infrastructure, manufacturing, distribution, and administration. Globally Resilient Supply Chains for Seasonal and Pandemic Influenza Vaccines outlines key findings and recommendations to bolster vaccine distribution, manufacturing, and supply chains for future seasonal and pandemic influenza events. This report addresses the challenges of manufacturing and distributing vaccines for both seasonal and pandemic influenza, highlighting the critical components of vaccine manufacturing and distribution and offering recommendations that would address gaps in the current global vaccine infrastructure.
Countering The Pandemic Threat Through Global Coordination On Vaccines The Influenza Imperative
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Author : National Academy of Medicine
language : en
Publisher: National Academies Press
Release Date : 2021-12-31
Countering The Pandemic Threat Through Global Coordination On Vaccines The Influenza Imperative written by National Academy of Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-12-31 with Medical categories.
The COVID-19 pandemic has laid bare the fragility of the global system of preparedness and response to pandemics and the fragmentation of our research and development ecosystem. The pandemic has provided a disruptive moment to advance new norms and frameworks for influenza. It also has demonstrated how innovative global public-private partnerships and coordination mechanisms can lead to rapid successes in viral vaccine research, manufacturing, and risk pooling. Countering the Pandemic Threat Through Global Coordination on Vaccines identifies ways to strengthen pandemic and seasonal influenza global coordination, partnerships, and financing. This report presents seven overarching recommendations for how the urgent influenza threat should be conceptualized and prioritized within the global pandemic preparedness and response agenda in the future.
Vaccines For Pandemic Influenza
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Author : Richard W Compans
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-09-18
Vaccines For Pandemic Influenza written by Richard W Compans and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-09-18 with Medical categories.
Recent years have seen unprecedented outbreaks of avian influenza A viruses. In particular, highly pathogenic H5N1 viruses have not only resulted in widespread outbreaks in domestic poultry, but have been transmitted to humans, resulting in numerous fatalities. The rapid expansion in their geographic distribution and the possibility that these viruses could acquire the ability to spread from person to person raises the risk that such a virus could cause a global pandemic with high morbidity and mortality. An effective influenza vaccine represents the best approach to prevent and control such an emerging pandemic. However, current influenza vaccines are directed at existing seasonal influenza viruses, which have little or no antigenic relationship to the highly pathogenic H5N1 strains. Concerns about pandemic preparedness have greatly stimulated research activities to develop eff- tive vaccines for pandemic influenza viruses, and to overcome the limitations inh- ent in current approaches to vaccine production and distribution. These limitations include the use of embryonated chicken eggs as the substrate for vaccine prod- tion, which is time-consuming and could involve potential biohazards in growth of new virus strains. Other limitations include the requirement that the current inac- vated influenza vaccines be administered using needles and syringes, requiring trained personnel, which could be a bottleneck when attempting to vaccinate large populations in mass campaigns. In addition, the current inactivated vaccines that are delivered by injection elicit limited protective immunity in the upper respiratory tract where the infection process is initiated.
Globally Resilient Supply Chains For Seasonal And Pandemic Influenza Vaccines
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Author : National Academy of Medicine
language : en
Publisher: National Academies Press
Release Date : 2021-12-31
Globally Resilient Supply Chains For Seasonal And Pandemic Influenza Vaccines written by National Academy of Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-12-31 with Medical categories.
Influenza viruses, both seasonal and pandemic, have the potential to disrupt the health and well-being of populations around the world. The global response to the COVID-19 pandemic and prior public health emergencies of international concern illustrate the importance of global preparedness and coordination among governments, academia, scientists, policy makers, nongovernmental organizations, the private sector, and the public to address the threat of pandemic influenza. These health emergencies have revealed opportunities to enhance global vaccine infrastructure, manufacturing, distribution, and administration. Globally Resilient Supply Chains for Seasonal and Pandemic Influenza Vaccines outlines key findings and recommendations to bolster vaccine distribution, manufacturing, and supply chains for future seasonal and pandemic influenza events. This report addresses the challenges of manufacturing and distributing vaccines for both seasonal and pandemic influenza, highlighting the critical components of vaccine manufacturing and distribution and offering recommendations that would address gaps in the current global vaccine infrastructure.
Guidance On Development And Implementation Of A National Deployment And Vaccination Plan For Vaccines Against Pandemic Influenza And Other Respiratory Viruses Of Pandemic Potential
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Author : World Health Organization
language : en
Publisher: World Health Organization
Release Date : 2023-12-11
Guidance On Development And Implementation Of A National Deployment And Vaccination Plan For Vaccines Against Pandemic Influenza And Other Respiratory Viruses Of Pandemic Potential written by World Health Organization and has been published by World Health Organization this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-12-11 with Medical categories.
Vaccines are powerful weapons in the fight against pandemic viruses as shown by responses to both the 2009 H1N1 influenza and the COVID-19 pandemics. However, planning for accessing, allocating and deploying vaccines in a pandemic situation is a complex endeavour, beset with multiple challenges at all levels – local, regional and global. The World Health Organization (WHO) and its partners have prepared this revised guidance document to assist countries update their national deployment and vaccination plans (NDVPs) by leveraging global learnings from past pandemic responses, including the recent COVID-19 vaccination effort. The development and testing of a NDVP would not only advance pandemic preparedness efforts but would also have benefits in terms of increasing national capabilities to manage other health emergencies which require emergency vaccination campaigns.
Report Of The Meeting With Industry To Discuss Common Activities For Deployment Of Pandemic Influenza Response Products
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Author :
language : en
Publisher: World Health Organization
Release Date : 2020-12-21
Report Of The Meeting With Industry To Discuss Common Activities For Deployment Of Pandemic Influenza Response Products written by and has been published by World Health Organization this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-12-21 with Medical categories.
Preparedness and readiness for responding to a global pandemic influenza requires the engagement of many stakeholders. To ensure the effective and efficient allocation and deployment of pandemic influenza products to the populations most in need, manufacturers of such products play a critical role in the entire supply chain. Under the auspices of the Pandemic Influenza Preparedness Framework, the World Health Organization (WHO) organized two consultations with relevant industry representatives. The meetings provided an opportunity to exchange information on existing preparedness activities, to review challenges for pandemic vaccine production and deployment pathways and to identify areas where WHO and industry partners need to work together, including in the planning of future simulation exercises involving industry.
Influenza Vaccines For The Future
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Author : Rino Rappuoli
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-10-28
Influenza Vaccines For The Future written by Rino Rappuoli and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-10-28 with Medical categories.
The emergence of H5N1 avian influenza in 1997 and of the influenza A H1N1 of swine origin in 2009 calls for new, rapid and sustainable solutions for both seasonal and pandemic influenza viruses. During the last ten years, science and technology have made enormous progress, and we are now able to monitor in real time the genetics of viruses while they spread globally, to make more powerful vaccines using novel adjuvants, and to generate viruses in the laboratory using reverse genetics. This volume not only provides state-of-the-art information on the biology of influenza viruses and on influenza vaccines, but is also designed to be a resource to face the present H1N1 pandemic and to plan for long-term global and sustainable solutions.
International Workshop On Covid 19 Lessons To Inform Pandemic Influenza Response Proceedings Of A Workshop
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Author : National Academy of Medicine
language : en
Publisher:
Release Date : 2022-02-14
International Workshop On Covid 19 Lessons To Inform Pandemic Influenza Response Proceedings Of A Workshop written by National Academy of Medicine and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-02-14 with Medical categories.
While the world continues to respond to the COVID-19 pandemic, novel influenza viruses persist as a constant pandemic threat. The global response to COVID-19 has pushed the boundaries on what is possible for rapid pandemic response in several areas, including vaccine research, development, manufacturing, equitable distribution, allocation, and administration. If well understood and sufficiently adapted, these actions could be applied to future pandemic and seasonal influenza vaccine preparedness efforts. However, developing and delivering these more effective vaccines to meet the demand goes beyond simply technical challenges and includes issues across governance, financing, research, supply chain, and public engagement. To address these challenges, the National Academies of Sciences, Engineering, and Medicine convened a virtual public workshop in May of 2021 to discuss the emerging evidence on unprecedented actions related to COVID-19 that could inform and advance pandemic and seasonal influenza vaccine preparedness efforts and subsequent response. This Proceedings of a Workshop provides a high-level summary of the presentations and discussions that occurred during the workshop.
The Domestic And International Impacts Of The 2009 H1n1 Influenza A Pandemic
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Author : Institute of Medicine
language : en
Publisher: National Academies Press
Release Date : 2010-07-04
The Domestic And International Impacts Of The 2009 H1n1 Influenza A Pandemic written by Institute of Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-07-04 with Medical categories.
In March and early April 2009, a new, swine-origin 2009-H1N1 influenza A virus emerged in Mexico and the United States. During the first few weeks of surveillance, the virus spread by human-to-human transmission worldwide to over 30 countries. On June 11, 2009, the World Health Organization (WHO) raised the worldwide pandemic alert level to Phase 6 in response to the ongoing global spread of the novel influenza A (H1N1) virus. By October 30, 2009, the H1N1 influenza A had spread to 191 countries and resulted in 5,700 fatalities. A national emergency was declared in the United States and the swine flu joined SARS and the avian flu as pandemics of the 21st century. Vaccination is currently available, but in limited supply, and with a 60 percent effectiveness rate against the virus. The story of how this new influenza virus spread out of Mexico to other parts of North America and then on to Europe, the Far East, and now Australia and the Pacific Rim countries has its origins in the global interconnectedness of travel, trade, and tourism. Given the rapid spread of the virus, the international scientific, public health, security, and policy communities had to mobilize quickly to characterize this unique virus and address its potential effects. The World Health Organization and Centers for Disease Control have played critical roles in the surveillance, detection and responses to the H1N1 virus. The Domestic and International Impacts of the 2009-H1N1 Influenza A Pandemic: Global Challenges, Global Solutions aimed to examine the evolutionary origins of the H1N1 virus and evaluate its potential public health and socioeconomic consequences, while monitoring and mitigating the impact of a fast-moving pandemic. The rapporteurs for this workshop reported on the need for increased and geographically robust global influenza vaccine production capacities; enhanced and sustained interpandemic demand for seasonal influenza vaccines; clear "triggers" for pandemic alert levels; and accelerated research collaboration on new vaccine manufacturing techniques. This book will be an essential guide for healthcare professionals, policymakers, drug manufacturers and investigators.
Pandemic Influenza
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Author : Jonathan Van-Tam
language : en
Publisher: CABI
Release Date : 2012
Pandemic Influenza written by Jonathan Van-Tam and has been published by CABI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with Communicable diseases categories.
With a strong emphasis on practicality, this book offers comprehensive coverage of the science and operational application of influenza epidemiology, virology and immunology, as well as vaccinology, pharmaceutical and public health measures, biomathematical modelling, policy issues and ethics. Each chapter raises key questions and answers them in clear and concise sections, detailing relevant modelling studies and further reading. This new 2nd Edition is comprehensively updated and includes:* major lessons from the 2009-10 pandemic* new contributions on surveillance, International Health Regul.