Guide To Signal Pathways In Immune Cells
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Guide To Signal Pathways In Immune Cells
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Author : E. Nigel Wardle
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-04-21
Guide To Signal Pathways In Immune Cells written by E. Nigel Wardle and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-04-21 with Medical categories.
To read current biomedical science, one has to have a working knowledge of how important effector molecules cause transduction of their signal within cells, altering the control of genes. This work aims to provide that basic knowledge for medical readers. Students of immunology or cell biology will note its relevance. One will learn how platelets, macrophages, neutrophils, T and B lymphocytes and natural killer cells perform their functions and how skin, breast, prostate and colon cancers emerge. The associated diagrams and tables are used to obviate extensive text. Appropriate references to articles and reviews by workers in each field are given so that further consideration can easily be undertaken. We are all at differing stages of our appreciation of immunology and of pat- physiology. Some persons will have a profound background in biochemistry or molecular biology. Others will have a reminiscence of lectures received years ago. Since this work is principally for clinical doctors, the sections that can be avoided at first reading are marked with an asterisk (*). Always proceed line by line and think of associations that you know. Do you feel comfortable with the statement, “Interleukin 6 stimulates glucose uptake in renal proximal tubular cells, and that action is associated with Stat3, PI3K/Akt, MAPKs and NF-kB signal pathways”? If not, please read on.
Guide To Signal Pathways In Immune Cells
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Author :
language : en
Publisher:
Release Date : 2009
Guide To Signal Pathways In Immune Cells written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009 with categories.
Signal Transduction Pathways In Autoimmunity
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Author : Amnon Altman
language : en
Publisher: Karger Medical and Scientific Publishers
Release Date : 2002
Signal Transduction Pathways In Autoimmunity written by Amnon Altman and has been published by Karger Medical and Scientific Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Medical categories.
The chapters included in this volume represent but a few examples of the close link between aberrant signaling pathways and autoimmune diseases. They cover a variety of cells (T, B and myeloid/monocytic cells), receptors (for antigen, Fc and cytokines) and intracellular signaling molecules (kinases, phosphatases, adapters and transcription factors) in the immune system. This book brings together clinical and experimental aspects of autoimmune disease and the fundamental science of intracellular signaling pathways. Therefore, it should be of interest to clinical investigators of autoimmune diseases as wll as to basic immunologists and cell biologists interested in the molecular basis of signal transduction in the immune system.
Targeting Signalling Pathways In Inflammatory Diseases
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Author : Uzma Saqib
language : en
Publisher: Frontiers Media SA
Release Date : 2023-08-14
Targeting Signalling Pathways In Inflammatory Diseases written by Uzma Saqib and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-08-14 with Medical categories.
Signaling By Toll Like Receptors
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Author : Gregory W. Konat
language : en
Publisher: CRC Press
Release Date : 2008-06-20
Signaling By Toll Like Receptors written by Gregory W. Konat and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-06-20 with Medical categories.
The discovery of toll-like receptors (TLRs) spurred the field of innate immunity into a renaissance after many years of neglect. Since then, TLR research has grown at an exponential rate. Taking an integrated methodological approach, Signaling by Toll-Like Receptors offers a comprehensive review of important techniques in molecular biology,
Kelley And Firestein S Textbook Of Rheumatology
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Author : Gary S. Firestein
language : en
Publisher: Elsevier Health Sciences
Release Date : 2016-06-21
Kelley And Firestein S Textbook Of Rheumatology written by Gary S. Firestein and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-06-21 with Medical categories.
Consult the definitive resource in rheumatology for an in-depth understanding of scientific advances as they apply to clinical practice. Masterfully edited by Drs. Gary S. Firestein, Ralph C. Budd, Sherine E. Gabriel, Iain B. McInnes, and James R. O'Dell, and authored by internationally renowned scientists and clinicians in the field, Kelley and Firestein’s Textbook of Rheumatology, 10th Edition, delivers the knowledge you need for accurate diagnoses and effective patient care. From basic science, immunology, anatomy, and physiology to diagnostic tests, procedures, and specific disease processes, this state-of-the-art reference provides a global, authoritative perspective on the manifestations, diagnosis and treatment of rheumatic diseases. An ideal balance of the basic science you need to know and how to apply that information to clinical practice. An integrated chapter format allows you to review basic science advances and their clinical implications in one place and get dependable, evidence-based guidance for the full range of rheumatologic diseases and syndromes. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. New content on the latest diagnostic perspectives and approaches to therapy, including five brand-new chapters: Metabolic Regulation of Immunity, Principles of Signaling, Research Methods in the Rheumatic Diseases, Novel Intracellular Targeting Agents, and IgG4-Related Diseases. New and expanded chapter topics on small molecule treatment, biologics, biomarkers, epigenetics, biosimilars, and cell-based therapies. More schematic diagrams clearly summarize information and facilitate understanding.
Immunopotentiators In Modern Vaccines
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Author : Virgil Schijns
language : en
Publisher: Elsevier
Release Date : 2005-12-19
Immunopotentiators In Modern Vaccines written by Virgil Schijns and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-12-19 with Medical categories.
Immunopotentiators in Modern Vaccines provides an in-depth insight and overview of a number of most promising immunopotentiators in modern vaccines. In contrast to existing books on the subject it provides recent data on the critical mechanisms governing the activity of vaccine adjuvants and delivery systems. Knowledge of immunological pathways and scenarios of the cells and molecules involved is described and depicted in comprehensive illustrations. - Contributions from leading international authorities in the field - Well-illustrated, informative figures present the interactions between immunopotentiators and the host immune system - Each chapter lists advantages and potential hurdles for achieving a practical application for the specific immunopentiator
Identification And Characterization Of Molecular Targets In Hepatocellular Carcinoma
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Author : Vinay Kumar
language : en
Publisher: Frontiers Media SA
Release Date : 2023-07-21
Identification And Characterization Of Molecular Targets In Hepatocellular Carcinoma written by Vinay Kumar and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-07-21 with Science categories.
the field of oncology and is the most common form of liver cancer. In some cases, HCC can be treated through surgery and ablations but can be extended to a full transplant. Risk factors for HCC have been elucidated in previous years, linking hepatitis viruses, diabetes, and alcohol-dependent conditions to the pathogenesis of HCC. Given the prevalence of HCC in global populations (currently >800,000 new cases per year, and rising), there is a requirement to identify molecular targets in HCC and develop new therapeutic strategies to manage and treat HCCs. New technologies and techniques, including gene sequencing, bioinformatics, and liquid biopsy, have helped identify molecular and genetic players involved in the development of HCC. As such, a comprehensive genetic/immune signature of HCC would be invaluable in the development of new therapeutics and treatment strategies, as well as early identification and management of HCC. There are currently various trials that implement a combination of already approved drugs to better the prognosis of patients suffering from HCC. There is, however, still room for improvement, and as our understanding of the various factors involved in HCC improves, so will the prognosis of patients suffering from HCC globally. This Research Topic aims to highlight the molecular and genetic targets that lead to the progression of Hepatocellular Carcinoma. We welcome Original Research, Reviews, and other article types.
Progress In The Diagnosis And Treatment Of Gliomas
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Author : Ying Mao
language : en
Publisher: Springer Nature
Release Date : 2024-08-29
Progress In The Diagnosis And Treatment Of Gliomas written by Ying Mao and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-08-29 with Medical categories.
This book provides the most current advancements in the medical care of glioma patients, accompanied by clinical cases. Clinical implementations of the new multilayered integrated diagnosis of gliomas according to WHO CNS5 are also demonstrated here. New adjuvant therapies, such as chemotherapy/targeted therapy, immunotherapy, and physiotherapy, are discussed in the book. The book also covers the applications of genomics and epigenomics of gliomas in clinical practice. In essence, this book shows the management of gliomas with new treatment modalities, which can prolong the overall survival time of patients fighting glioma. The translation was done with the help of artificial intelligence. The present version has been revised technically and linguistically by the authors in collaboration with a professional translator.
Comprehensive Toxicology
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Author :
language : en
Publisher: Elsevier
Release Date : 2017-12-01
Comprehensive Toxicology written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-12-01 with Science categories.
Comprehensive Toxicology, Third Edition, Fifteen Volume Set discusses chemical effects on biological systems, with a focus on understanding the mechanisms by which chemicals induce adverse health effects. Organized by organ system, this comprehensive reference work addresses the toxicological effects of chemicals on the immune system, the hematopoietic system, cardiovascular system, respiratory system, hepatic toxicology, renal toxicology, gastrointestinal toxicology, reproductive and endocrine toxicology, neuro and behavioral toxicology, developmental toxicology and carcinogenesis, also including critical sections that cover the general principles of toxicology, cellular and molecular toxicology, biotransformation and toxicology testing and evaluation. Each section is examined in state-of-the-art chapters written by domain experts, providing key information to support the investigations of researchers across the medical, veterinary, food, environment and chemical research industries, and national and international regulatory agencies. Thoroughly revised and expanded to 15 volumes that include the latest advances in research, and uniquely organized by organ system for ease of reference and diagnosis, this new edition is an essential reference for researchers of toxicology. Organized to cover both the fundamental principles of toxicology and unique aspects of major organ systems Thoroughly revised to include the latest advances in the toxicological effects of chemicals on the immune system Features additional coverage throughout and a new volume on toxicology of the hematopoietic system Presents in-depth, comprehensive coverage from an international author base of domain experts