Guidebook To The Extracellular Matrix And Adhesion Proteins


Guidebook To The Extracellular Matrix And Adhesion Proteins
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Guidebook To The Extracellular Matrix Anchor And Adhesion Proteins


Guidebook To The Extracellular Matrix Anchor And Adhesion Proteins
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Author : Thomas Kreis
language : en
Publisher: Sambrook and Tooze Publications
Release Date : 1999

Guidebook To The Extracellular Matrix Anchor And Adhesion Proteins written by Thomas Kreis and has been published by Sambrook and Tooze Publications this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999 with Mathematics categories.


Intended for postgraduate and professional researchers in biochemistry, biomedical sciences and cell biology, this text offers a guide to the extracellular matrix and adhesion proteins.



Guidebook To The Extracellular Matrix And Adhesion Proteins


Guidebook To The Extracellular Matrix And Adhesion Proteins
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Author : Thomas Kreis
language : en
Publisher: Sambrook and Tooze Publication at Oxford University Press
Release Date : 1993

Guidebook To The Extracellular Matrix And Adhesion Proteins written by Thomas Kreis and has been published by Sambrook and Tooze Publication at Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993 with Language Arts & Disciplines categories.


A compendium of the proteins found in the extracellular matrix and those known to be involved in cell-cell contact and adhesion. Organized alphabetically, it summarizes the essential features of these proteins, giving key references and drawing together information from wide-ranging sources.



Guidebook To The Extracellular Matrix And Adhesion Proteins


Guidebook To The Extracellular Matrix And Adhesion Proteins
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Author : Thomas Kreis
language : en
Publisher:
Release Date : 2023

Guidebook To The Extracellular Matrix And Adhesion Proteins written by Thomas Kreis and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023 with Cell adhesion molecules categories.


Intended for postgraduate and professional researchers in biochemistry, biomedical sciences and cell biology, this text offers a guide to the extracellular matrix and adhesion proteins.



Guidebook To The Cytoskeletal And Motor Proteins


Guidebook To The Cytoskeletal And Motor Proteins
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Author : Thomas Kreis
language : en
Publisher: Sambrook and Tooze Publication at Oxford University Press
Release Date : 1993

Guidebook To The Cytoskeletal And Motor Proteins written by Thomas Kreis and has been published by Sambrook and Tooze Publication at Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993 with Medical categories.


These Sambrook and Tooze Guidebooks provide students and research professionals with a unique source of reference to the most up-to-date information available on the proteins involved in cell adhesion, the cytoskeleton, and the extracellular matrix. The first concise compendium of the molecules of the cytoskeleton and those involved in cell movement, this book summarizes the essential features of these proteins, drawing together information from a widely-scattered literature. There has been an explosion of knowledge about the structure, function, and distribution of these proteins, and new ones are being discovered rapidly. The introductory chapters provide excellent overviews and each entry suggests effective methods for learning about the essentials of each protein supported by key references for in-depth reading.



Extracellular Matrix Pathobiology And Signaling


Extracellular Matrix Pathobiology And Signaling
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Author : Nikos Karamanos
language : en
Publisher: Walter de Gruyter
Release Date : 2012-08-31

Extracellular Matrix Pathobiology And Signaling written by Nikos Karamanos and has been published by Walter de Gruyter this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-08-31 with Science categories.


Over the last decades cell biology and biological chemistry have increasingly turned their attention to the space between cells and revealed an elaborate network of macromolecules essential for structural support, cell adhesion and signaling. This comprehensive handbook of the extracellular matrix will give an overview of the current state of knowledge of matrix components (structure and function), their role in heath and disease (matrix pathobiology) and new aspects related to pharmacological targeting. It will provide an introduction to the extracellular matrix and detailed sections and chapters on: Importance of extracellular matrix in health and disease Matrix proteoglycans (aggrecan, versican, perlecan, SLRPs, syndecans, glypicans, serglycin) Matrix proteinases (remodeling, would healing, regulatory roles in health and disease, metalloproteinases, cystein proteases, plasmin and plasminogen activator system) Glycobiology (hyaluronan and sulfated glycosaminoglycans in cancer, inflammation and metabolic control) Collagens (supramolecular assembly, proteins binding collagen, scaffolds, bacterial and mutated collagens, procollagen proteinases) Cell surface receptors (integrins, syndecans, mechanical strain and TGFb, CD44 and DDR). Biotechnological and pharmacological outlook (matrix regulation by growth factors, hyaluronidases, pathobiology, disease targeting, delivery systems, EMT and proteomics). "The book Extracellular Matrix: Pathobiology and Signaling provides a comprehensive and up to date collection of very relevant topics for understanding the various facets of extracellular matrix and its interactions with cells in normal tissue as well as in disease. It represents the current front-line and will serve as a reference for extracellular matrix and posttranslational modifications." Dick Heinegård, Department of Clinical Sciences Lund, Section Rheumatology, Lund University, Sweden



The Extracellular Matrix An Overview


The Extracellular Matrix An Overview
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Author : Robert Mecham
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-02-16

The Extracellular Matrix An Overview written by Robert Mecham and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-02-16 with Science categories.


Knowledge of the extracellular matrix (ECM) is essential to understand cellular differentiation, tissue development, and tissue remodeling. This volume of the series “Biology of Extracellular Matrix” provides a timely overview of the structure, regulation, and function of the major macromolecules that make up the extracellular matrix. It covers topics such as collagen types and assembly of collagen-containing suprastructures, basement membrane, fibronectin and other cell-adhesive glycoproteins, proteoglycans, microfibrils, elastin, fibulins and matricellular proteins, such as thrombospondin. It also explores the concept that ECM components together with their cell surface receptors can be viewed as intricate nano-devices that allow cells to physically organize their 3-D-environment. Further, the role of the ECM in human disease and pathogenesis is discussed as well as the use of model organisms in elucidating ECM function.



Extracellular Matrix Protocols


Extracellular Matrix Protocols
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Author : Charles Streuli
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-02-05

Extracellular Matrix Protocols written by Charles Streuli and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-02-05 with Science categories.


It is now widely accepted that much of the dynamic function of cells and tissues is regulated from outside the cell by the extracellular matrix. In ad- tion to its conventional role in providing a scaffold for building tissues, the extracellular matrix acts as a directional highway for cellular movement and provides instructional information for promoting survival, proliferation, and differentiation. Indeed, the extracellular matrix is beginning to take a starring role in the choreography of cell and tissue function. The diverse roles of the extracellular matrix are reflected in its highly complicated structure, consisting of an ever increasing number of components. Yet the mechanisms of extracellular matrix assembly and how they influences cell behavior are only just beginning to be understood. In order to solve these problems new methodologies are, of necessity, being developed. Many of these technologies are highly sophisticated and are currently available only in a ha- ful of laboratories. However, we believe that they can readily be transported and established by other researchers. Thus, the purpose of Extracellular Matrix Protocols is to present some of these complicated techniques in a style that is relatively easy to reproduce.



Adhesion Protein Protocols


Adhesion Protein Protocols
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Author : Elisabetta Dejana
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-02-03

Adhesion Protein Protocols written by Elisabetta Dejana and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-02-03 with Science categories.


Adhesion molecules are of fundamental importance in the regulation of immunity, inflammation, tissue remodeling, and embryonic development. They comprise different families of homologous proteins, such as selectins, integrins, cadherins, and immunoglobins. In addition, beyond these groups, other str- tures with adhesive properties, such as proteoglycans, occludin, and CD44, have been characterized recently. An understanding of the type and characteristics of adhesive molecules expressed by the different cell types and the possibility of manipulating their activity promises considerable clinical potential. Antibodies, small peptidic and nonpeptidic molecules, have recently been used to inhibit thrombosis by blocking platelet aggregation or inflammation through inhibition of leukocyte infiltration and adhesion. Inhibitors of adhesive molecules are used in expe- mental systems for the study of tumor growth and dissemination. Among major goals in the field are the identification of new members of the known adhesive protein families and of independent new adhesive structures. After structural characterization, even more demanding is the study of the biological activity of the new proteins, and the development of simple, rapid tests for the screening of possible inhibitors. In this regard, the production of such reagents as fragments and antibodies would help define the structure–function relati- ship of individual proteins. Data available in the literature show the complexity of the adhesive process and how different molecular epitopes might contribute to the adhesive properties of a single structure. Finally, a new area of investi- tion is the characterization of the intracellular signaling cascade triggered by the engagement of transmembrane adhesive proteins.



Cell Adhesion Molecules And Matrix Proteins


Cell Adhesion Molecules And Matrix Proteins
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Author : Shaker A. Mousa
language : en
Publisher:
Release Date : 1998

Cell Adhesion Molecules And Matrix Proteins written by Shaker A. Mousa and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998 with Cell adhesion molecules categories.




Cell Biology Of Extracellular Matrix


Cell Biology Of Extracellular Matrix
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Author : Elizabeth D. Hay
language : en
Publisher: Springer
Release Date : 1981

Cell Biology Of Extracellular Matrix written by Elizabeth D. Hay and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 1981 with Juvenile Nonfiction categories.


At a recent meeting to discuss the domains of cell biology, I put forth a case for the extracellular matrix, even though my argument ran the risk of falling on deaf ears. After all, the matrix is EXTRAcellular, outside the cells. In this book, however, the authors make a compelling case for the relevance of the matrix to cellular concerns. Not only are numerous cell types, including many epithelia, quite caught up in the business of manufacturing matrix components, but also most of them contain matrix molecules in exoskeletons that are attached to the plasmalemma and that organize or otherwise influence the affairs of the cyto plasm. The idea of this book is to present the extracellular matrix to cell biolo gists of all levels. The authors are active and busy investigators, recognized experts in their fields, but all were enthusiastic about the prospect of writing for this audience. The chapters are not "review" articles in the usual sense, nor are they rehashes of symposium talks; they were written specifically for this book and they present the "state of the art" in engaging style, with ample references to more technical or historical reviews. The book is rich in electron micro graphs and diagrams and for many of the latter, as well as for the design of the cover, we are indebted to Sylvia J. Keene, medical illustrator for the Department of Anatomy at Harvard Medical Scrool. We also owe special thanks to Susan G.