Handbook Of Bioseparations
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Handbook Of Bioseparations
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Author : Satinder Ahuja
language : en
Publisher: Elsevier
Release Date : 2000-06-23
Handbook Of Bioseparations written by Satinder Ahuja and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-06-23 with Technology & Engineering categories.
It is generally recognized that the commercial success of biotechnology products is highly dependent on the successful development and application of high-powered separation and purification methods. In this practical and authoritative handbook, the separation of proteins, nucleic acids, and oligonucleotides from biological matrices is covered from analytical to process scales. Also included in a chapter on the separation of monoclonal antibodies, which have found numerous uses as therapeutic and diagnostic agents. Analytical techniques include an interesting montage of chromatographic methods, capillary electrophoresis, isoelectric focusing, and mass spectrometry. Among separation and purification methods, liquid-liquid distribution, displacement chromatography, expanded bed adsorption, membrane chromatography, and simulated moving bed chromatography are covered at length. Regulatory and economic considerations are addressed, as are plant and process equipment and engineering process control. A chapter on future developments highlights the application of DNA chip arrays as well as evolving methodologies for a large number of drugs that are under development for treatment of cancer, AIDS, rheumatoid arthritis, and Alzheimer's disease. Handbook of Bioseparations serves as an essential reference and guidebook for separation scientists working in the pharmaceutical and biotechnology industries, academia, and government laboratories.Key Features* Covers bioseparations of proteins, nucleic acids, and monoclonal antibodies* Encompasses both analytical and process-scale methods* Elucidates the importance of engineering process control* Details selection of plant and process equipment* Addresses economic considerations* Discusses future developments
Bioseparations Science And Engineering
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Author : Roger G. Harrison
language : en
Publisher: Oxford University Press, USA
Release Date : 2015
Bioseparations Science And Engineering written by Roger G. Harrison and has been published by Oxford University Press, USA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015 with Science categories.
An updated edition of a comprehensive and authoritative chemical engineering textbook on bioseparations science, updated to include new information on topics like moment analysis, chromatography, and evaporation.
Bioseparations
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Author : Paul A. Belter
language : en
Publisher: Wiley-Interscience
Release Date : 1988-02-22
Bioseparations written by Paul A. Belter and has been published by Wiley-Interscience this book supported file pdf, txt, epub, kindle and other format this book has been release on 1988-02-22 with Science categories.
Offers a concise introduction to the separation and purification of biochemicals. Bridges two scientific cultures, providing an introduction to bioseparations for scientists with no background in engineering and for engineers with little grounding in biology. The authors supplement the ideas by simple worked examples, making the techniques of bioseparations easy to learn. Discusses removal of insolubles, product isolation, purification and polishing.
Handbook Of Industrial Membranes
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Author : K. Scott
language : en
Publisher: Elsevier
Release Date : 1995-12-20
Handbook Of Industrial Membranes written by K. Scott and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995-12-20 with Technology & Engineering categories.
This manual contains necessary and useful information and data in an easily accessible format relating to the use of membranes. Membranes are among the most important engineering components in use today, and each year more and more effective uses for membrane technologies are found - for example: water purification, industrial effluent treatment, solvent dehydration by per-vaporation, recovery of volatile organic compounds, protein recovery, bioseparations and many others.The pace of change in the membrane industry has been accelerating rapidly in recent years, occasioned in part by the demand of end-users, but also as a result of the investment in R&D by manufacturers. To reflect these changes the author has obtained the latest information from some of the leading suppliers in the business. In one complete volume this unique handbook gives practical guidance to using selected membrane processes in individual industries while also providing a useful guide to equipment selection and usage.
Handbook Of Process Chromatography
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Author : Gunter Jagschies
language : en
Publisher: Elsevier
Release Date : 2007-12-08
Handbook Of Process Chromatography written by Gunter Jagschies and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-12-08 with Technology & Engineering categories.
This book will update the original edition published in 1997. Since the publication of the first edition, the biotechnology and biologics industries have gained extensive knowledge and experience in downstream processing using chromatography and other technologies associated with recovery and purification unit operations. This book will tie that experience together for the next generation of readers.Updates include:- sources and productivity- types of products made today- experiences in clinical and licensed products - economics- current status of validation- illustrations and tables- automated column packing- automated systemsNew topics include:- the use of disposables- multiproduct versus dedicated production- design principles for chromatography media and filters- ultrafiltration principles and optimization- risk assessments- characterization studies- design space- platform technologies- process analytical technologies (PATs)- biogenerics - comparability assessmentsKey Features:- new approaches to process optimiaztion- use of patform technologies- applying risk assessment to process design
Biopharmaceutical Production Technology 2 Volume Set
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Author : Ganapathy Subramanian
language : en
Publisher: John Wiley & Sons
Release Date : 2012-08-20
Biopharmaceutical Production Technology 2 Volume Set written by Ganapathy Subramanian and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-08-20 with Medical categories.
Systematically addressing the key steps and challenges along the biopharmaceutical production process, this two volume handbook provides key knowledge for medium to large scale producers of biopharmaceuticals. The volumes are divided into six major parts, on upstream technologies, protein recovery, process development, analytical technologies, quality control, and an outlook section that addresses new and emerging technologies, such as single-use processes and integrated process design. With contributions by some 40 experts from academia, as well as small and large biopharmaceutical companies, this unique handbook is full of valuable first-hand knowledge on how to produce biopharmaceuticals in a cost-effective and quality-controlled manner.
Principles Of Bioseparations Engineering
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Author : Raja Ghosh
language : en
Publisher: World Scientific Publishing Company
Release Date : 2006-10-23
Principles Of Bioseparations Engineering written by Raja Ghosh and has been published by World Scientific Publishing Company this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-10-23 with Technology & Engineering categories.
Bioseparations engineering deals with the scientific and engineering principles involved in large-scale separation and purification of biological products. It is a key component of most chemical engineering/biotechnology/bioprocess engineering programmes. This book discusses the underlying principles of bioseparations engineering written from the perspective of an undergraduate course. It covers membrane based bioseparations in much more detail than some of the other books on bioseparations engineering. Based largely on the lecture notes the author developed to teach the course, this book is especially suitable for use as an undergraduate level textbook, as most other textbooks are targeted at graduate students.
Industrial Chemical Separation
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Author : Timothy C. Frank
language : en
Publisher: Walter de Gruyter GmbH & Co KG
Release Date : 2023-08-07
Industrial Chemical Separation written by Timothy C. Frank and has been published by Walter de Gruyter GmbH & Co KG this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-08-07 with Technology & Engineering categories.
A fresh new treatment written by industry insiders, this work gives readers a remarkably clear view into the world of chemical separation. The authors review distillation, extraction, adsorption, crystallization, and the use of membranes – providing historical perspective, explaining key features, and offering insights from personal experience. The book is for engineers and chemists with current or future responsibility for chemical separation on a commercial scale – in its design, operation, or improvement – or for anyone wanting to learn more about chemical separation from an industrial point of view. The result is a compelling survey of popular technologies and the profession, one that brings the art and craft of chemical separation to life. Ever wonder how popular separation technologies came about, how a particular process functions, or how mass transfer units differ from theoretical stages? Or perhaps you want some pointers on how to begin solving a separation problem. You will find clear explanations and valuable insights into these and other aspects of industrial practice in this refreshing new survey.
Scale Up And Optimization In Preparative Chromatography
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Author : Anurag Rathore
language : en
Publisher: CRC Press
Release Date : 2002-09-26
Scale Up And Optimization In Preparative Chromatography written by Anurag Rathore and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-09-26 with Science categories.
This text offers fundamental analysis of the underlying physicochemical principles to select optimal modes of interaction, design efficient separations, and increase productivity in the manufacture of novel therapeutics and pharmaceuticals.
Handbook Of Isolation And Characterization Of Impurities In Pharmaceuticals
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Author : Satinder Ahuja
language : en
Publisher: Elsevier
Release Date : 2003-06-26
Handbook Of Isolation And Characterization Of Impurities In Pharmaceuticals written by Satinder Ahuja and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-06-26 with Medical categories.
The United States Food and Drug Administration (FDA) and other regulatory bodies around the world require that impurities in drug substance and drug product levels recommended by the International Conference on Harmonisation (ICH) be isolated and characterized. Identifying process-related impurities and degradation products also helps us to understand the production of impurities and assists in defining degradation mechanisms. When this process is performed at an early stage, there is ample time to address various aspects of drug development to prevent or control the production of impurities and degradation products well before the regulatory filing and thus assure production of a high-quality drug product.This book, therefore, has been designed to meet the need for a reference text on the complex process of isolation and characterization of process-related (synthesis and formulation) impurities and degradation products to meet critical requlatory requirements.It's objective is to provide guidance on isolating and characterizing impurities of pharmaceuticals such as drug candidates, drug substances, and drug products. The book outlines impurity identification processes and will be a key resource document for impurity analysis, isolation/synthesis, and characterization.- Provides valuable information on isolation and characterization of impurities. - Gives a regulatory perspective on the subject. - Describes various considerations involved in meeting regulatory requirements. - Discusses various sources of impurities and degredation products.