Scale Up And Optimization In Preparative Chromatography
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Scale Up And Optimization In Preparative Chromatography
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Author : Anurag Rathore
language : en
Publisher: CRC Press
Release Date : 2002-09-26
Scale Up And Optimization In Preparative Chromatography written by Anurag Rathore and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-09-26 with Medical categories.
Presenting guidelines to predict and improve separation system performance, this book contains numerous case studies illustrating the practice of scale-up principles in process development. It offers solutions to limitations that occur in real-world purification schemes; methods to model, optimize, and characterize nonlinear separation processes; data comparisons from all stages of production; and industrial separation schemes for products such as synthetic molecules, antibody fragments, IgG, growth factors, and plasmid DNA. The book covers external constraints, separation economics, correlations for transport and kinetic phenomena, and the configuration and parameters of column design.
Scale Up And Optimization In Preparative Chromatography
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Author : Anurag Rathore
language : en
Publisher: CRC Press
Release Date : 2002-09-26
Scale Up And Optimization In Preparative Chromatography written by Anurag Rathore and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-09-26 with Medical categories.
Presenting guidelines to predict and improve separation system performance, this book contains numerous case studies illustrating the practice of scale-up principles in process development. It offers solutions to limitations that occur in real-world purification schemes; methods to model, optimize, and characterize nonlinear separation processes; data comparisons from all stages of production; and industrial separation schemes for products such as synthetic molecules, antibody fragments, IgG, growth factors, and plasmid DNA. The book covers external constraints, separation economics, correlations for transport and kinetic phenomena, and the configuration and parameters of column design.
Mathematical Modeling And Scale Up Of Liquid Chromatography
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Author : Tingyue Gu
language : en
Publisher: Springer
Release Date : 2015-04-06
Mathematical Modeling And Scale Up Of Liquid Chromatography written by Tingyue Gu and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-04-06 with Science categories.
Tingyue Gu's second edition provides a comprehensive set of nonlinear multicomponent liquid chromatography (LC) models for various forms of LC, such as adsorption, size exclusion, ion-exchange, reversed-phase, affinity, isocratic/gradient elution and axial/radial flow LC. Much has advanced since the first edition of this book and the author's software, described here, is now used for teaching and research in 32 different countries. This book comes together with a complete software package with graphical user interface for personal computers, offered free for academic applications. Additionally, this book provides detailed methods for parameter estimation of mass transfer coefficients, bed voidage, particle porosity and isotherms. The author gives examples of how to use the software for predicitons and scale-up. In contrast to the first edition, authors do not need to deal with complicated math. Instead, they focus on how to obtain a few parameters for simulation and how to compare simulation results with experimental data. After reading the detailed descriptions in the book, a reader is able to use the simulation software to investigate chromatographic behavior without doing actual experiments. This book is aimed at readers who are interested in learning about LC behaviors and at those who want to scale up LC for preparative- and large-scale applications. Both academic personnel and industrial practitioners can benefit from the use of the book. This new edition includes: - New models and software for pellicular (cored) beads in liquid chromatography - Introduction of user-friendly software (with graphical user interface) - Detailed descriptions on how to use the software - Step-by-step instructions on parameter estimation for the models - New mass-transfer correlations for parameter estimation - Experimental methods for parameter estimation - Several actual examples using the model for product development and scale-up - Updated literature review
Preparative Chromatography For Separation Of Proteins
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Author : Arne Staby
language : en
Publisher: John Wiley & Sons
Release Date : 2017-02-02
Preparative Chromatography For Separation Of Proteins written by Arne Staby and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-02-02 with Technology & Engineering categories.
Preparative Chromatography for Separation of Proteins addresses a wide range of modeling, techniques, strategies, and case studies of industrial separation of proteins and peptides. • Covers broad aspects of preparative chromatography with a unique combination of academic and industrial perspectives • Presents Combines modeling with compliantce useing of Quality-by-Design (QbD) approaches including modeling • Features a variety of chromatographic case studies not readily accessible to the general public • Represents an essential reference resource for academic, industrial, and pharmaceutical researchers
Ion Exchange Chromatography And Related Techniques
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Author : Pavel Nesterenko
language : en
Publisher: Elsevier
Release Date : 2023-11-15
Ion Exchange Chromatography And Related Techniques written by Pavel Nesterenko and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-11-15 with Technology & Engineering categories.
Ion-Exchange Chromatography and Related Techniques defines the current state-of-the-art in ion-exchange chromatography and related techniques and their implementation in laboratory and industrial practice. This book provides a compact source of information to facilitate the transfer of knowledge and experience acquired by separation science specialists to colleagues from diverse backgrounds who need to acquire fundamental and practical information to facilitate progress in research and management functions reliant on information acquired by separation. Individual chapters written by recognized experts lending credibility to the work will allow this book to serve as a high value reference source of current information for analytical and biopharmaceutical chemists. - Includes individual chapters written by recognized authoritative and visionary experts in the field to provide an overview and focused treatment of a single topic - Presents comprehensive coverage of ion-exchange techniques from theory, to methods, to selected applications for ions and biopolymers - Provides Tables and diagrams with commonly used data to facilitate practical work, comparison of results and decision-making
Handbook Of Hplc
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Author : Danilo Corradini
language : en
Publisher: CRC Press
Release Date : 2016-04-19
Handbook Of Hplc written by Danilo Corradini and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-04-19 with Science categories.
High performance liquid chromatography (HPLC) is one of the most widespread analytical and preparative scale separation techniques used for both scientific investigations and industrial and biomedical analysis. Now in its second edition, this revised and updated version of the Handbook of HPLC examines the new advances made in this field since the
Chemometrics In Chromatography
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Author : Łukasz Komsta
language : en
Publisher: CRC Press
Release Date : 2018-02-02
Chemometrics In Chromatography written by Łukasz Komsta and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-02-02 with Science categories.
Chemometrics uses advanced mathematical and statistical algorithms to provide maximum chemical information by analyzing chemical data, and obtain knowledge of chemical systems. Chemometrics significantly extends the possibilities of chromatography and with the technological advances of the personal computer and continuous development of open-source software, many laboratories are interested in incorporating chemometrics into their chromatographic methods. This book is an up-to-date reference that presents the most important information about each area of chemometrics used in chromatography, demonstrating its effective use when applied to a chromatographic separation.
Handbook Of Size Exclusion Chromatography And Related Techniques
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Author : Chi-San Wu
language : en
Publisher: CRC Press
Release Date : 2003-11-04
Handbook Of Size Exclusion Chromatography And Related Techniques written by Chi-San Wu and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-11-04 with Science categories.
Documenting critical advances in this rapidly evolving field, the Second Edition highlights the need for new applications and technologies that assist in the determination of molecular weight and molecular weight distributions of polymers in an accurate, efficient manner. This volume presents the latest findings from a international team of specialists and continues to inspire and extend practical applications of size exclusion chromatography (SEC). It includes six new chapters covering high-speed size exclusion chromatography, SEC of low molecular weight materials, and the extended family of techniques, from two-dimensional liquid chromatography to high osmotic pressure chromatography.
Comprehensive Biotechnology
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Author :
language : en
Publisher: Elsevier
Release Date : 2019-07-17
Comprehensive Biotechnology written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-07-17 with Science categories.
Comprehensive Biotechnology, Third Edition, Six Volume Set unifies, in a single source, a huge amount of information in this growing field. The book covers scientific fundamentals, along with engineering considerations and applications in industry, agriculture, medicine, the environment and socio-economics, including the related government regulatory overviews. This new edition builds on the solid basis provided by previous editions, incorporating all recent advances in the field since the second edition was published in 2011. Offers researchers a one-stop shop for information on the subject of biotechnology Provides in-depth treatment of relevant topics from recognized authorities, including the contributions of a Nobel laureate Presents the perspective of researchers in different fields, such as biochemistry, agriculture, engineering, biomedicine and environmental science
Bioseparations Science And Engineering
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Author : Roger G. Harrison
language : en
Publisher: Oxford University Press
Release Date : 2015-01-27
Bioseparations Science And Engineering written by Roger G. Harrison and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-01-27 with Technology & Engineering categories.
Designed for undergraduates, graduate students, and industry practitioners, Bioseparations Science and Engineering fills a critical need in the field of bioseparations. Current, comprehensive, and concise, it covers bioseparations unit operations in unprecedented depth. In each of the chapters, the authors use a consistent method of explaining unit operations, starting with a qualitative description noting the significance and general application of the unit operation. They then illustrate the scientific application of the operation, develop the required mathematical theory, and finally, describe the applications of the theory in engineering practice, with an emphasis on design and scaleup. Unique to this text is a chapter dedicated to bioseparations process design and economics, in which a process simular, SuperPro Designer® is used to analyze and evaluate the production of three important biological products. New to this second edition are updated discussions of moment analysis, computer simulation, membrane chromatography, and evaporation, among others, as well as revised problem sets. Unique features include basic information about bioproducts and engineering analysis and a chapter with bioseparations laboratory exercises. Bioseparations Science and Engineering is ideal for students and professionals working in or studying bioseparations, and is the premier text in the field.