Handbook Of Microbiome And Gut Brain Axis In Alzheimer S Disease

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Handbook Of Microbiome And Gut Brain Axis In Alzheimer S Disease

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Author : G.M. Pasinetti
language : en
Publisher: IOS Press
Release Date : 2022-07-05

Handbook Of Microbiome And Gut Brain Axis In Alzheimer S Disease written by G.M. Pasinetti and has been published by IOS Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-07-05 with Medical categories.

Despite being confined to the gastrointestinal tract, the gut microbiome has a wide impact on human physiology, supplementing its host’s biochemistry in a complex symbiotic relationship. Research in the field has evolved rapidly in the last decade, and we are now developing a better understanding of how our gut microbiome can influence our immune systems, metabolism, neurological signaling, and perhaps most unexpectedly, our brains; a phenomenon described as the gut-brain-axis. This book, ‘Handbook of Microbiome and Gut-Brain-Axis in Alzheimer’s Disease’, sets out to explore the complex role of the microbiome with regard to Alzheimer’s disease (AD). The microbiome is a critical and often overlooked aspect of immunity, which in turn plays a role in cognition. The book presents current research into the gut microbiota and its far-reaching impacts on cognitive function and neurodegeneration. Interventions, including probiotic supplementation, fecal transfer, and supplementation with microbial metabolites, are discussed, as is the use of certain probiotics to study the effects of the gut microbiota on behavior and cognitive function, and as potential therapeutics for AD. Other topics covered include the influence of the gut and oral microbiota on immune inflammatory signals: cytokines, neuroendocrine hormones, bacterial components, neuroactive molecules, and microbial metabolites. The book is divided into four sections, each covering a research area pertinent to the gut-brain-axis and its relationship with cognitive function and AD. It will be of interest to all those whose work includes the study and understanding of these complex, multi-variable biological mechanisms, particularly in the context of cognitive function and AD. The cover shows a color edited MRI image of a sagittal section of a neurological control brain of Dr. Giulio Maria Pasinetti.

Handbook Of Intervention And Alzheimer S Disease

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Author : C.A. Raji
language : en
Publisher: IOS Press
Release Date : 2024-02-15

Handbook Of Intervention And Alzheimer S Disease written by C.A. Raji and has been published by IOS Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-02-15 with Medical categories.

It is almost 120 years since Alzheimer’s disease (AD) was first reported, and the concept of managing some of the modifiable risk factors associated with the disease has been present from the outset. Intervening to manage risk factors as a way of tackling AD is not new, but optimizing brain health as a way of minimizing risk and maximizing the potential benefits of revolutionary new treatments for AD is becoming increasingly important. This book, the Handbook of Intervention and Alzheimer’s Disease, presents 47 papers exploring factors which may either inspire or inform future treatment and clinical trials. While novel interventions such as anti-amyloid immunotherapy present great opportunities, they may also increase the risk of brain bleeds and edema, which in turn may lead to adverse clinical outcomes. Such adverse outcomes are demonstrably more likely to occur in persons with poor brain health, so improved management of the risk factors which make up the AD preventome will also minimize the risks associated with such novel therapies. The papers in this volume can therefore be thought of as offering insight into those factors that can optimize brain health or providing key insights into interventions which may achieve such outcomes. Together with its companion volume on prevention, the book provides a comprehensive overview of strategies for tackling Alzheimer’s disease, and will be of interest to all those working in the field. Cover illustration: Improved hypoperfusion (resolving blue colors) on ASL MRI Z-score maps superimposed on structural MRI scans at baseline and one year in a PET amyloid-positive research participant with cognitive complaints undergoing one year of multi-domain personalized brain health interventions (vascular disease management, dietary optimization, sustained physical activity etc.). Permission to use this figure was granted both by the study P.I. Dr. David Merrill, MD, PhD, of the Pacific Neuroscience Institute and the research participant.

Tryptamine Microbiota Deregulated Aminoacyl Trna Biosynthesis

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Author : Elena L. Paley
language : en
Publisher: Elsevier
Release Date : 2024-05-31

Tryptamine Microbiota Deregulated Aminoacyl Trna Biosynthesis written by Elena L. Paley and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-05-31 with Science categories.

Tryptamine Microbiota-Deregulated Aminoacyl-tRNA Biosynthesis: A Conceptual Evolution of the Role of Microbiota Tryptamine in Human Diseases provides a detailed investigation into tryptamine, its underlying mechanisms, and metabolism across multiple diseases. The book explores key concepts of tryptamine, its biosynthetic pathways, and its influence in disease, specifically focusing on the Alzheimer's disease-associated gut bacterial sequence (ADAS). Various neurodegenerative conditions are covered alongside cancer, diabetes, infections, and chromosomal aberrations. Additionally, a chapter on gut tryptamine in domestic and agricultural animals is included. The book closes with case studies involving FDG-PET imaging in the context of tryptamine-treated mouse models and Alzheimer's disease patients.This book elucidates the implications of the gut microbiota-mediated tryptamine metabolism for human health, sharing insights into disease etiology, mechanisms, testing, prevention, and treatment. It is an ideal reference for researchers across the biomedical sciences. - Provides a detailed investigation into tryptamine and its role in human health - Explores the relationship between microbiome tryptamine metabolome and a range of diseases, including diabetes, cancer, Alzheimer's disease and Parkinson's disease - Considers the role of tryptamine in cell death and the impairment of genome activities - Paves the way for advances in disease prevention and treatment pathways

Handbook Of Neurodegenerative Disorders

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Author : Musthafa M. Essa
language : en
Publisher: Springer Nature
Release Date : 2024-10-23

Handbook Of Neurodegenerative Disorders written by Musthafa M. Essa and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-10-23 with Science categories.

This Handbook discusses the pathology, etiology, pathogenesis, and therapeutic interventions of different neurodegenerative diseases. The initial section of the Handbook reviews the recent advances in understanding neurodegenerative diseases and the commonalities and differences between the major pathologies. The subsequent section presents recent developments in understanding fundamental biological mechanisms that influence the onset and development of neurodegenerative diseases. It provides current biomedical studies that are aimed at identifying the underlying causes of neurodegeneration. The book also examines the recent observations from biological, cellular, and studies from the model organisms for gaining mechanistic insights into neurodegenerative disorders. It also presents the epidemiological and genetics studies relevant to clinical aspects of neurodegenerative diseases. The book's subsequent chapters offer new and more effective therapeutic strategies to combat these devastating diseases. Towards the end, the Handbook presents recent advances in molecular diagnostics for neurodegenerative disorders and a perspective on the future directions to provide a framework for further developments and refinements of molecular diagnostics to combat neurodegenerative diseases.

Microbial Endocrinology The Microbiota Gut Brain Axis In Health And Disease

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Author : Mark Lyte
language : en
Publisher: Springer
Release Date : 2014-07-05

Microbial Endocrinology The Microbiota Gut Brain Axis In Health And Disease written by Mark Lyte and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-07-05 with Science categories.

The field of microbial endocrinology is expressly devoted to understanding the mechanisms by which the microbiota (bacteria within the microbiome) interact with the host (“us”). This interaction is a two-way street and the driving force that governs these interactions are the neuroendocrine products of both the host and the microbiota. Chapters include neuroendocrine hormone-induced changes in gene expression and microbial endocrinology and probiotics. This is the first in a series of books dedicated to understanding how bi-directional communication between host and bacteria represents the cutting edge of translational medical research, and hopefully identifies new ways to understand the mechanisms that determine health and disease.​

Clinical Handbook Of Adhd Assessment And Treatment Across The Lifespan

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Author : Johnny L. Matson
language : en
Publisher: Springer Nature
Release Date : 2023-11-21

Clinical Handbook Of Adhd Assessment And Treatment Across The Lifespan written by Johnny L. Matson and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-11-21 with Psychology categories.

The handbook examines the latest research and clinical advancements in assessing and treating ADHD (attention deficit hyperactivity disorder) across the lifespan. It synthesizes the most current research data and trends combined with best-practice interventions to form a comprehensive, state-of-the-art resource. The handbook identifies the most relevant, effective treatments for individuals with ADHD. Key areas of coverage include: Core symptoms of ADHD in minority children. Lifestyles for children with ADHD. Digital interventions for children and adolescents with ADHD. Telemedicine to manage ADHD across the lifespan. Healthcare use and costs for adults with ADHD. The Clinical Handbook of ADHD Assessment and Treatment Across the Lifespan is an essential reference for researchers, professors, and graduate students as well as clinicians and other professionals across such interrelated disciplines as clinical child, school, and developmental psychology, child and adolescent psychiatry, social work, rehabilitation medicine/therapy, pediatrics, and special education.

The Gut Brain Axis

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Author : Niall Hyland
language : en
Publisher: Academic Press
Release Date : 2016-05-13

The Gut Brain Axis written by Niall Hyland and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-05-13 with Medical categories.

The Gut-Brain Axis: Dietary, Probiotic, and Prebiotic Interventions on the Microbiota examines the potential for microbial manipulation as a therapeutic avenue in central nervous system disorders in which an altered microbiota has been implicated, and explores the mechanisms, sometimes common, by which the microbiota may contribute to such disorders. - Focuses on specific areas in which the microbiota has been implicated in gut-brain communication - Examines common mechanisms and pathways by which the microbiota may influence brain and behavior - Identifies novel therapeutic strategies targeted toward the microbiota in the management of brain activity and behavior

Dementia Unveiled A Comprehensive Guide To Holistic Care And Well Being

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Author : Dr. Spineanu Eugenia
language : en
Publisher: Dr. Spineanu Eugenia
Release Date : 2025-03-12

Dementia Unveiled A Comprehensive Guide To Holistic Care And Well Being written by Dr. Spineanu Eugenia and has been published by Dr. Spineanu Eugenia this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-03-12 with Medical categories.

"Dementia Unveiled: A Comprehensive Guide to Holistic Care and Well-being" offers an in-depth exploration of dementia care, blending medical insights with holistic approaches to enhance the quality of life for individuals living with dementia. This treatise delves into the multifaceted aspects of dementia, covering topics such as risk factors, diagnosis, treatment options, and the importance of holistic care. From understanding the intricate anatomy of the brain to exploring innovative therapeutic approaches and advocating for social engagement and support networks, this guide provides valuable insights for caregivers, healthcare professionals, and individuals affected by dementia. With a focus on compassion, empowerment, and evidence-informed practice, "Dementia Unveiled" serves as a vital resource for navigating the complexities of dementia with knowledge and empathy.

The Whole Body Guide To Gut Health

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Author : Heidi Moretti
language : en
Publisher: Sourcebooks, Inc.
Release Date : 2021-03-02

The Whole Body Guide To Gut Health written by Heidi Moretti and has been published by Sourcebooks, Inc. this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-03-02 with Health & Fitness categories.

Help get your gut back on track with this simple, whole-body plan Your gut encompasses your digestive organs and all their resident microbes—and its health affects all the other systems in your body. Experience the physical and mental benefits of a healthy gut biome with this research-based guide. Find out how to care for your body, alleviate digestive distress, and soothe a wide variety of ailments, from heartburn and irritable bowel syndrome to depression and anxiety. Learn the five principles of good gut health, explore the science of probiotics, and refer to at-a-glance lists of foods to enjoy, limit, or avoid. Go deeper with practical advice for exercise, stress reduction, and mindfulness practices to help boost your overall mood, energy, and even your memory. A holistic 2-week plan—Kick-start your gut health routine with a customizable 2-week plan that incorporates healthy eating, exercise, meditation, and more. Tasty, gut-healthy recipes—Treat your gut right with 50 feel-good options like the Lemon-Ginger Smoothie, Wild Salmon and Fennel Scramble, Fermented Fried Rice with Vegetables, and more. Simple symptom tracking—Use a handy template to track your symptoms, identify possible triggers, and chart your progress as you make changes. Help restore balance in your gut with The Whole-Body Guide to Gut Health.

Essential Guide To Neurodegenerative Disorders

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Author : Wael Mohamed
language : en
Publisher: Elsevier
Release Date : 2024-11-24

Essential Guide To Neurodegenerative Disorders written by Wael Mohamed and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-11-24 with Medical categories.

Handbook of Neurodegenerative Disorders: Mechanism, Diagnostic and Therapeutic Advances provides a comprehensive review on the current biomedical studies aimed at identifying the underlying causes of neurodegeneration. This book reviews the most recent developments in molecular and cellular processes altered during neurodegeneration. Divided into four parts, the first covers the mechanism of cell death in neurodegeneration. The second section reviews the recent progress in gene and gene products in neurodegeneration, including Huntington's disease, Parkinson's disease, Friedreich' s ataxia, and spinal muscular atrophy. The final sections cover the current and future diagnostic techniques of neurodegenerative disorders along with therapeutic approaches. - Reviews big data and neurodegeneration disorders, including gene mapping - Examines the structural basis of protein assembly into amyloid filaments in neurodegenerative disease - Covers the progress and challenges of pharmacotherapy of neurodegenerative disorders