Handbook Of Proteases In Cancer
DOWNLOAD
Download Handbook Of Proteases In Cancer PDF/ePub or read online books in Mobi eBooks. Click Download or Read Online button to get Handbook Of Proteases In Cancer book now. This website allows unlimited access to, at the time of writing, more than 1.5 million titles, including hundreds of thousands of titles in various foreign languages. If the content not found or just blank you must refresh this page
Handbook Of Proteases In Cancer
DOWNLOAD
Author : Sajal Chakraborti
language : en
Publisher: CRC Press
Release Date : 2024-12-17
Handbook Of Proteases In Cancer written by Sajal Chakraborti and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-12-17 with Science categories.
This handbook provides comprehensive coverage of the application of proteases in cancer therapy. Proteases make up to two percent of the human genome and play a critical role in the tumor microenvironment. The book delves into the applications of natural, synthetic, and non-coding RNAs in cancer therapy. It highlights how effective targeting of relevant proteases can help in cancer diagnosis and treatment. It covers the systems biology and bioinformatics approach in cancer drug development. The book is meant for researchers and professionals in cancer research, biochemistry, and physiology.
Handbook Of Proteases In Cancer
DOWNLOAD
Author : Sajal Chakraborti
language : en
Publisher: CRC Press
Release Date : 2024-12-13
Handbook Of Proteases In Cancer written by Sajal Chakraborti and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-12-13 with Science categories.
This handbook provides comprehensive coverage of the role of proteases and the associated biochemical pathways in cancer development and metastasis. Proteases make up about 2% of the human genome and play a critical role in the tumor microenvironment. Handbook of Proteases in Cancer: Cellular and Molecular Aspects introduces the major classes of proteases and the signal transduction mechanisms associated with cancer initiation and progression. It discusses the role of inflammation and immune responses in proteases-induced cancer. The book covers cancer-induced gene expression and apoptotic and necrotic pathways in cancer. This is useful for researchers and professionals in cancer research, biochemistry, and physiology. Key Features • Provides insights on the roles of proteases and anti-proteases in the tumor microenvironment. • Covers various cancer-induced apoptotic and necrotic pathways. • Discusses the mechanisms by which proteases induce an increase in inflammation, immune response, and gene expression. • Covers the function of protease-activated receptors in cancer. • Reviews the different gene expression pathways and the ways they become erratic during protease-induced cancer.
Handbook Of Proteases In Cancer
DOWNLOAD
Author : Sajal Chakraborti
language : en
Publisher:
Release Date : 2025
Handbook Of Proteases In Cancer written by Sajal Chakraborti and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025 with categories.
"This handbook provides comprehensive coverage of the application of proteases in cancer therapy. Proteases make up to two percent of the human genome and play a critical role in the tumor microenvironment. The book delves into the applications of natural, synthetic, and non-coding RNAs in cancer therapy. It highlights how effective targeting of relevant proteases can help in cancer diagnosis and treatment. It covers the systems biology and bioinformatics approach in cancer drug development"--
Handbook Of Proteolytic Enzymes Volume 1
DOWNLOAD
Author : Alan J. Barrett
language : en
Publisher: Elsevier
Release Date : 2012-12-02
Handbook Of Proteolytic Enzymes Volume 1 written by Alan J. Barrett and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Science categories.
Handbook of Proteolytic Enzymes, Second Edition, Volume 1: Aspartic and Metallo Peptidases is a compilation of numerous progressive research studies on proteolytic enzymes. This edition is organized into two main sections encompassing 328 chapters. This handbook is organized around a system for the classification of peptidases, which is a hierarchical one built on the concepts of catalytic type, clan, family and peptidase. The concept of catalytic type of a peptidase depends upon the chemical nature of the groups responsible for catalysis. The recognized catalytic types are aspartic, cysteine, metallo, serine, threonine, and the unclassified enzymes, while clans and families are groups of homologous peptidases. Homology at the level of a family of peptidases is shown by statistically significant relationship in amino acid sequence to a representative member called the type example, or to another member of the family that has already been shown to be related to the type example. Each chapter discusses the history, activity, specificity, structural chemistry, preparation, and biological aspects of the enzyme. This book will prove useful to enzyme chemists and researchers.
Pathophysiological Aspects Of Proteases In Cancer
DOWNLOAD
Author : Sajal Chakraborti
language : en
Publisher: Elsevier
Release Date : 2024-10-22
Pathophysiological Aspects Of Proteases In Cancer written by Sajal Chakraborti and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-10-22 with Science categories.
Pathophysiological Aspects of Proteases in Cancer provides a comprehensive overview of the multifaceted field of proteases in the cellular environment and focuses on the recently elucidated functions of complex proteolytic systems in physiology and pathophysiology. The book both gives insights on the general aspects of the role of proteases in cancer, their role as diagnostics and prognostics biomarkers, their impact on chemoresistance, and the future cutting-edge technologies like cocktail therapies and Cyber Knife technology. Given the breadth and depth of information covered in the respective contributions, the book will be immensely useful for researchers in oncology and working to identify targets for drug development.Multidisciplinary in scope, the book bridges the gap between fundamental and translational research, with applications in the biomedical and pharmaceutical industry, making it a thought-provoking read for basic and applied scientists engaged in biomedical research. - Gives insight into the spectrum of proteases, protease inhibitors, and protease interactors involved at the cellular and molecular level in cancer development - Gives a comprehensive overview of the role of proteases in modulating cellular metabolism and chemoresistance to better understand how proteases play in early to the end point in cancer development and metastasis - Provides a multidisciplinary approach demonstrating the biochemical and signal transduction mechanisms associated with dysregulation of proteases, leading to the manifestation of various diseases - Highlights the roles and regulation of different types of proteases, as well as their synthetic and endogenous inhibitors - Bridges the gap between fundamental and translational research, with applications in the biomedical and pharmaceutical industry
Proteases Structure And Function
DOWNLOAD
Author : Klaudia Brix
language : en
Publisher: Springer Science & Business Media
Release Date : 2014-01-21
Proteases Structure And Function written by Klaudia Brix and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-01-21 with Science categories.
Proteolysis is an irreversible posttranslational modification affecting each and every protein from its biosynthesis to its degradation. Limited proteolysis regulates targeting and activity throughout the lifetime of proteins. Balancing proteolysis is therefore crucial for physiological homeostasis. Control mechanisms include proteolytic maturation of zymogens resulting in active proteases and the shut down of proteolysis by counteracting endogenous protease inhibitors. Beyond the protein level, proteolytic enzymes are involved in key decisions during development that determine life and death – from single cells to adult individuals. In particular, we are becoming aware of the subtle role that proteases play in signaling events within proteolysis networks, in which the enzymes act synergistically and form alliances in a web-like fashion. Proteases come in different flavors. At least five families of mechanistically distinct enzymes and even more inhibitor families are known to date, many family members are still to be studied in detail. We have learned a lot about the diversity of the about 600 proteases in the human genome and begin to understand their physiological roles in the degradome. However, there are still many open questions regarding their actions in pathophysiology. It is in this area where the development of small molecule inhibitors as therapeutic agents is extremely promising. Approaching proteolysis as the most important, irreversible post-translational protein modification essentially requires an integrated effort of complementary research disciplines. In fact, proteolytic enzymes seem as diverse as the scientists working with these intriguing proteins. This book reflects the efforts of many in this exciting field of research where team and network formations are essential to move ahead.
Activation Of Viruses By Host Proteases
DOWNLOAD
Author : Eva Böttcher-Friebertshäuser
language : en
Publisher: Springer
Release Date : 2018-05-22
Activation Of Viruses By Host Proteases written by Eva Böttcher-Friebertshäuser and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-05-22 with Medical categories.
This book will give an overview on viruses undergoing proteolytic activation through host proteases. The chapters will be organized in three themed parts, the first part describing respective viruses and their characteristics in detail. In the second part the molecular and cellular biology of the proteases involved as well as their physiological functions will be further explored. The third part will contain a chapter on protease inhibitors that are promising tools for antiviral therapy. This book will engage scholars in virology and medical microbiology as well as researchers with an interest in enzymology and protein structure and function relationship.
The Royal Marsden Hospital Handbook Of Cancer Chemotherapy
DOWNLOAD
Author : David Brighton
language : en
Publisher: Churchill Livingstone
Release Date : 2005
The Royal Marsden Hospital Handbook Of Cancer Chemotherapy written by David Brighton and has been published by Churchill Livingstone this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with Medical categories.
"The Royal Marsden Hospital Handbook of Cancer Chemotherapy is a unique resource for health care professionals caring for patients with cancer. It gives a detailed overview of disease-specific management, treatment regimens and supportive care. The roles and skills required by staff and the problems that may arise for patients undergoing chemotherapy, treatment are highlighted." "The book has been written for a multi-professional audience, both qualified and in training, including medical staff, pharmacists, rehabilitation therapists, nurses and those requiring a greater understanding of caring for patients undergoing chemotherapy."--BOOK JACKET.
Cell Surface Proteases
DOWNLOAD
Author :
language : en
Publisher: Elsevier
Release Date : 2003-05-03
Cell Surface Proteases written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-05-03 with Science categories.
Cell Surface Proteases provides a comprehensive overview of these important enzymes that catalyze the hydrolysis of a protein as it degrades to a simpler substance. In the 1990s, an explosion of new discoveries shed light on the role of cell surface proteases and extended it beyond degradation of extracellular matrix components to include its influence on growth factors, cell signaling, and other cellular events. This volume unites the scientific literature from across disciplines and teases out unified themes of interactions between cell surface proteases and interconnecting cell surface-related systems -- including integrins and other adhesion molecules. Scientists and students involved in developmental biology, cell biology and disease processes will find this an indispensable resource.* Provides an overview of the entire field of cell surface proteases in a single volume* Presents major issues and astonishing discoveries at the forefront of modern developmental biology and developmental medicine * A thematic volume in the longest-running forum for contemporary issues in developmental biology with over 30 years of coverage
Advances In Enzyme Regulation
DOWNLOAD
Author : George Weber
language : en
Publisher: Elsevier
Release Date : 2002-09-19
Advances In Enzyme Regulation written by George Weber and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-09-19 with Medical categories.
Volume 42 lives up to its goal of advancing a few steps ahead of the general front of mammalian enzymic and metabolic regulation studies. This volume contains papers of 25 outstanding scientists working at the cutting edge of metabolic regulation. Much of the volume focuses on novel aspects of signal transduction with an emphasis on nuclear expression. One of the highlights of this volume is the Special Symposium Lecture. This was given for 15 years by Sir Hans A. Krebs who passed away 20 years ago. It was now given by Professor Sir Hans L. Kornberg, University Professor at Boston University. These volumes continue to be a source of information and inspiration and a laboratory and advanced teaching companion. The immediate and long-range significance of these cutting-edge presentations of these novel topics should be immediately clear to the reader.