Activation Of Viruses By Host Proteases
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Activation Of Viruses By Host Proteases
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Author : Eva Böttcher-Friebertshäuser
language : en
Publisher: Springer
Release Date : 2018-05-22
Activation Of Viruses By Host Proteases written by Eva Böttcher-Friebertshäuser and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-05-22 with Medical categories.
This book will give an overview on viruses undergoing proteolytic activation through host proteases. The chapters will be organized in three themed parts, the first part describing respective viruses and their characteristics in detail. In the second part the molecular and cellular biology of the proteases involved as well as their physiological functions will be further explored. The third part will contain a chapter on protease inhibitors that are promising tools for antiviral therapy. This book will engage scholars in virology and medical microbiology as well as researchers with an interest in enzymology and protein structure and function relationship.
Structure Function Relationships Of Human Pathogenic Viruses
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Author : Andreas Holzenburg
language : en
Publisher: Springer Science & Business Media
Release Date : 2002-04-30
Structure Function Relationships Of Human Pathogenic Viruses written by Andreas Holzenburg and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-04-30 with Medical categories.
Structure-Function Relationships of Human Pathogenic Viruses provides information on the mechanisms by which viruses enter the cell, replicate, package their DNA into capsids and mature into new virions. The relation between structural features and the pathogenicity and oncogenicity of some of the most relevant human viral pathogens are demonstrated and the acquisition of defense mechanisms through virus-host interactions are presented. In contrast to textbooks, this volume combines timely research data to provide a holistic view of viral pathogenesis. Furthermore Structure-Function Relationships of Human Pathogenic Viruses illustrates in a single volume the fundamental processes involved in viral life cycles using up-to-date information from research laboratories around the world. Knowledge of these processes is crucial to develop rationales for the design of future drugs. The timeliness of the data and the comprehensive yet concise approach this book takes in order to present the world of viral pathogens should make it a frontrunner in higher education and R&D.
Serine Proteases
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Author : Anil K. Sharma
language : en
Publisher: Walter de Gruyter GmbH & Co KG
Release Date : 2023-10-24
Serine Proteases written by Anil K. Sharma and has been published by Walter de Gruyter GmbH & Co KG this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-10-24 with Science categories.
Serine proteases play significant roles in healh and human disease. Abnormal expression and activities of serine proteases have been linked to the pathogenesis of many diseases. The book presents correlation between serine proteases and human diseases. It helps the reader understand classification, catalytic mechanism and types of serine proteases and their role in human disease pathogenesis at mechanistic level. The chapters explain the role of serine proteases in various diseases including respiratory disorders and cancer. It also covers the therapeutic importance of serine proteases as drug target and explains the mechanistic insights of serine proteases inhibitors. Serine protease are known to play crucial role in biological processes but disturbance in their equilibrium can result in serious health conditions. To maintain homeostasis, serine protease inhibitors come in action and inhibit proteases. Several serine protease inhibitors have been identified and many more are being designed as novel compounds for inhibitions of proteases that provide management of comorbidities. Therefore, this book will serve as a useful reference for students and researchers to understand physiological role of serine proteases and their association with initiation and progression of human diseases. It will also help to develop some strategies to develop serine proteases inhibitors as drug target of serine proteases at cellular and molecular level.
100 Years Of Virology
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Author : Charles H. Calisher
language : en
Publisher: Springer Science & Business Media
Release Date : 1999-08-03
100 Years Of Virology written by Charles H. Calisher and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999-08-03 with Medical categories.
Comprises papers of Dr Ursula Hoff, including correspondence and photographs, relating to her study of Charles Conder.
Proteases Of Infectious Agents
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Author : Ben Dunn
language : en
Publisher: Elsevier
Release Date : 1999-07-01
Proteases Of Infectious Agents written by Ben Dunn and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999-07-01 with Science categories.
Proteases are enzymes that essentially "eat" protein. Without proteases, infectious organisms cannot properly mount an attack against a host. It is for this reason that proteases have become popular targets for drug discovery. Research has shown that if you can inhibit the protease, you can defend against the invading microbe. The defense against HIV, the virus that causes AIDS, is the best-documented case of the efficacy of protease inhibitors. Researchers are now trying to deploy this strategy against several infectious agents. This book gives information that is useful in that search.Proteases of Infectious Agents collects reviews from leading experts describing the latest information on the properties of key enzymes from a variety of viruses, fungi, and parasites. Each chapter provides the critical facts needed to initiate a drug discovery effort in that particular area. Includes information on the basic biology and function of proteases Provides global survey of current research efforts in protease inhibitors Illustrates how structure-based drug design targets effective and selective compounds Highlights important diseases that provide economically important targets Describes the role of proteases as important new targets for drug discovery
Evolution Of Innate Immunity In Eukarya Advances And Implications
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Author : Jean L. Scholz
language : en
Publisher: Frontiers Media SA
Release Date : 2022-05-06
Evolution Of Innate Immunity In Eukarya Advances And Implications written by Jean L. Scholz and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-05-06 with Medical categories.
Pocket Companion To Robbins Cotran Pathologic Basis Of Disease E Book
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Author : Richard N Mitchell
language : en
Publisher: Elsevier Health Sciences
Release Date : 2011-05-25
Pocket Companion To Robbins Cotran Pathologic Basis Of Disease E Book written by Richard N Mitchell and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-05-25 with Medical categories.
This Pocket Companion to Robbins and Cotran Pathologic Basis of Disease, 8th Edition offers rapid, portable access to the most important pathology facts and concepts. Richard Mitchell, MD, PhD, Vinay Kumar, MBBS, MD, FRCPath, Nelson Fausto, MD, Abul K. Abbas, MBBS, and Jon Aster, MD assemble all of the key data and principles of pathology in a concise, at-a-glance format and fit them into your pocket for quick reference anytime. The result is a superb source for quick answers and an efficient review tool on any aspect of pathology. Assembles all of the key data and principles you need to know for exams and rotations. Presents information in a concise, at-a-glance format. Fits into your pocket, for a convenient reference any time. Offers abundant page references to the parent text, making additional information easy to find. Completely updated to reflect the latest knowledge and techniques across all areas of pathology.
Pocket Companion To Robbins And Cotran Pathologic Basis Of Disease
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Author : Richard N. Mitchell
language : en
Publisher: Elsevier Health Sciences
Release Date : 2011-04-08
Pocket Companion To Robbins And Cotran Pathologic Basis Of Disease written by Richard N. Mitchell and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-04-08 with Medical categories.
This Pocket Companion to Robbins and Cotran Pathologic Basis of Disease, 8th Edition offers rapid, portable access to the most important pathology facts and concepts. Richard Mitchell, MD, PhD, Vinay Kumar, MBBS, MD, FRCPath, Nelson Fausto, MD, Abul K. Abbas, MBBS, and Jon Aster, MD assemble all of the key data and principles of pathology in a concise, at-a-glance format and fit them into your pocket for quick reference anytime. The result is a superb source for quick answers and an efficient review tool on any aspect of pathology. Assembles all of the key data and principles you need to know for exams and rotations. Presents information in a concise, at-a-glance format. Fits into your pocket, for a convenient reference any time. Offers abundant page references to the parent text, making additional information easy to find. Completely updated to reflect the latest knowledge and techniques across all areas of pathology.
Genetics Of Influenza Viruses
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Author : P. Palese
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Genetics Of Influenza Viruses written by P. Palese and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
With the advent of genetic engineering methods and improved biochemical tech niques, much has been learned about the replication of influenza viruses, their structure and their epidemiology. It appears that the time is ripe to review these efforts and to provide a molecular perspective of influenza virology. It is hoped that this book will stimulate our thinking, help us in designing new experiments, and possibly show avenues leading to the control of the diseases associated with influenza viruses. Peter Palese, New York, N. Y. August 1983 David W. Kingsbury, Memphis, Tenn. Contents List of Contributors. . . . . . . . . . . . . . . . . XV 1. The Evolution of Influenza Viral Genetics - A Perspective. By E. D. Kilbourne. . . . . . . . . . . . . . . . 1 I. Introduction. . . . . . . . . . . . . . . . . 1 II. The Development of Modern Influenza Viral Genetics 2 A. Early Evidence of Genetic Variation in the Laboratory 2 B. Application of Formal Genetic Techniques to Studies of Influenza Virus . . . . . . . 3 C. Genetic Markers. . . . . . . . . 3 D. Development of Plaquing Systems. . . 4 E. The Use of Conditional Lethal Mutants 5 F. New Approaches in Influenza Virus Genetics. 6 1. The Biochemical Identification of Viral Gene Products in the Unambiguous Definition of Viral Inheritance . . . 6 2. Mapping of the Influenza Virus Genome by Correlative Physico-Chemical and Biological Techniques. . . . . . 7 3. The Application of Molecular Biological Techniques to the Study of Viral Genetic Variation. . . . . . . . . 8 4. Oligonucleotide Mapping of Viral RNA's . . . . . . . 8 5. Contribution of Protein and RNA Sequencing to Influenza Viral Genetics-Intragenic Mapping . . . . . . . 8 III. Viral Genetics and the Understanding of Viral Virulence and Pathogenicity . . . . . . . . . . .. . . . . . . .
Evolution Molecular Mechanisms And The Strategies To Combat Antimicrobial Resistance Amr A One Health Approach
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Author : Nayeem Ahmad
language : en
Publisher: Frontiers Media SA
Release Date : 2025-02-21
Evolution Molecular Mechanisms And The Strategies To Combat Antimicrobial Resistance Amr A One Health Approach written by Nayeem Ahmad and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-02-21 with Science categories.
Humanity, animals, and the ecosystem are seriously threatened by antimicrobial resistance. A significant reason is the inappropriate use of antimicrobials in the human, animal, and environmental sectors as well as the global spread of resistant bacteria and resistance genes. Lately, the use of antimicrobials in animals raised for human consumption has become a significant public health issue. The environment also has a big impact in the interface between human and animal health through biodiversity loss, climate change, and pollution. A sustainable balance and optimization of the health of people, animals, and ecosystems are the goals of the comprehensive, unifying approach known as “One Health”. To battle and contain antimicrobial resistance within a One Health strategy, rigorous antimicrobial resistance surveillance along with strict execution of the core plan and action should be carried out at various sectors individually and collectively, at the national and worldwide level.