Evolution Molecular Mechanisms And The Strategies To Combat Antimicrobial Resistance Amr A One Health Approach

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Evolution Molecular Mechanisms And The Strategies To Combat Antimicrobial Resistance Amr A One Health Approach
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Author : Nayeem Ahmad
language : en
Publisher: Frontiers Media SA
Release Date : 2025-02-21
Evolution Molecular Mechanisms And The Strategies To Combat Antimicrobial Resistance Amr A One Health Approach written by Nayeem Ahmad and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-02-21 with Science categories.
Humanity, animals, and the ecosystem are seriously threatened by antimicrobial resistance. A significant reason is the inappropriate use of antimicrobials in the human, animal, and environmental sectors as well as the global spread of resistant bacteria and resistance genes. Lately, the use of antimicrobials in animals raised for human consumption has become a significant public health issue. The environment also has a big impact in the interface between human and animal health through biodiversity loss, climate change, and pollution. A sustainable balance and optimization of the health of people, animals, and ecosystems are the goals of the comprehensive, unifying approach known as “One Health”. To battle and contain antimicrobial resistance within a One Health strategy, rigorous antimicrobial resistance surveillance along with strict execution of the core plan and action should be carried out at various sectors individually and collectively, at the national and worldwide level.
Mechanisms Of Antibiotic Resistance
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Author : Jun Lin
language : en
Publisher: Frontiers Media SA
Release Date : 2015-06-01
Mechanisms Of Antibiotic Resistance written by Jun Lin and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-06-01 with Antibiotics categories.
Antibiotics represent one of the most successful forms of therapy in medicine. But the efficiency of antibiotics is compromised by the growing number of antibiotic-resistant pathogens. Antibiotic resistance, which is implicated in elevated morbidity and mortality rates as well as in the increased treatment costs, is considered to be one of the major global public health threats (www.who.int/drugresistance/en/) and the magnitude of the problem recently prompted a number of international and national bodies to take actions to protect the public (http://ec.europa.eu/dgs/health_consumer/docs/road-map-amr_en.pdf: http://www.who.int/drugresistance/amr_global_action_plan/en/; http://www.whitehouse.gov/sites/default/files/docs/carb_national_strategy.pdf). Understanding the mechanisms by which bacteria successfully defend themselves against the antibiotic assault represent the main theme of this eBook published as a Research Topic in Frontiers in Microbiology, section of Antimicrobials, Resistance, and Chemotherapy. The articles in the eBook update the reader on various aspects and mechanisms of antibiotic resistance. A better understanding of these mechanisms should facilitate the development of means to potentiate the efficacy and increase the lifespan of antibiotics while minimizing the emergence of antibiotic resistance among pathogens.
Antimicrobial Resistance
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Author : Mihai Mareș
language : en
Publisher:
Release Date : 2021
Antimicrobial Resistance written by Mihai Mareș and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021 with Drug resistance in microorganisms categories.
Antimicrobial Resistance New Insights
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Author : Ghulam Mustafa
language : en
Publisher: BoD – Books on Demand
Release Date : 2025-06-25
Antimicrobial Resistance New Insights written by Ghulam Mustafa and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-06-25 with Science categories.
This comprehensive book provides a timely and authoritative overview of the latest advances in antimicrobial resistance (AMR), bringing together leading experts to share their knowledge on the complex mechanisms of AMR and the latest clinical recommendations for diagnosis, treatment, and prevention. The book delves into how AMR is a critical global health threat driven by the misuse of antibiotics in medicine, agriculture, and the environment, undermining treatment effectiveness and food security. The volume highlights urgent needs for molecular research, global collaboration, and innovative solutions such as nanotechnology and alternative therapies to combat the spread of multidrug-resistant pathogens. It also emphasizes the importance of responsible antimicrobial use, improved surveillance, and coordinated action across sectors to manage and prevent AMR sustainably. With a balanced view of the current state of knowledge, this book highlights areas of uncertainty and controversy and identifies future research directions. The book is an essential resource for researchers and clinicians seeking to stay up-to-date with the latest advances, students and academics looking for a comprehensive and authoritative textbook, and industry professionals and policymakers interested in understanding the latest developments and challenges in the field. The book will provide them a unique opportunity to explore the complex interplay between AMR and gain a deeper understanding of the challenges and opportunities that lie ahead, ultimately aiming to contribute to developing effective strategies to combat AMR and improve human health globally. This book is a self-contained collection of scholarly papers targeting an audience of practicing medical and basic researchers, academicians, MD/Ph.D. students and scientists.
Emerging Paradigms For Antibiotic Resistant Infections Beyond The Pill
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Author : Mayank Gangwar
language : en
Publisher: Springer Nature
Release Date : 2024-11-18
Emerging Paradigms For Antibiotic Resistant Infections Beyond The Pill written by Mayank Gangwar and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-11-18 with Science categories.
This book delves into antibiotic resistance, offering insights into its emergence, mechanisms, and impact on global health. The book also scrutinizes over-prescription, agricultural use, and the scarcity of new drug development, while spotlighting the role of globalization in its propagation. It moves beyond conventional approaches, examining alternative strategies like phage therapy, immunotherapy, and nanotechnology. Highlighting precision diagnostics and the importance of policy implications, it navigates through public health strategies, surveillance, and international collaborations. Finally, it glimpses into the future, delineating the challenges, opportunities, and the urgency of action required to steer away from a post-antibiotic era. This book serves as an invaluable resource for students, researchers, and scientists in the fields of medicine, pharmacy, microbiology, and public health.
Antimicrobials Antibiotic Resistance Antibiofilm Strategies And Activity Methods
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Author : Sahra Kırmusaoğlu
language : en
Publisher: BoD – Books on Demand
Release Date : 2019-04-03
Antimicrobials Antibiotic Resistance Antibiofilm Strategies And Activity Methods written by Sahra Kırmusaoğlu and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-04-03 with Medical categories.
To prevent bacterial adherence, invasion and infection, antimicrobials such as antibiotics are being used and vastly researched nowdays. Several factors such as natural selection, mutations in genes, the presence of efflux pumps, impermeability of the cell wall, structural changes in enzymes and receptors, biofilm formation, and quorum sensing cause microorganisms to develop resistance against antimicrobials. Isolates that synthesize extended spectrum-β-lactamases (ESBL), induced β-lactamases (IBL), carbapenamases, metallo-β-lactamases (MBLs), and New Delhi metallo-β-lactamases (NDM) have emerged. Determining virulence factors such as biofilms and the level of antimicrobial activities of antimicrobial agents alone and in combination with appropriate doses against microorganisms is very important for the diagnosis, inhibition, and prevention of microbial infection. The goal of this book is to provide information on all these topics.
Antimicrobial Resistance
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Author : Vinay Kumar
language : en
Publisher: Springer Nature
Release Date : 2022-01-03
Antimicrobial Resistance written by Vinay Kumar and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-03 with Medical categories.
Antimicrobial resistance (AMR) is a global public health threat that needs immediate attention and action from the scientific community. This book compiles and presents the latest and most important aspects of AMR, including the biology involved, its persistence and spread, and novel approaches to tackle this threat. The book first describes the mechanisms and spread of AMR, and then discusses the various approaches and strategies for combating it. Important topics include, microbial pathogenesis, AMR traits and major mechanisms underlying drug-resistance and the emerging strategies and technologies for combating AMR. Emphasis has been given on current developments about natural products including potent phyto-molecules, antimicrobial peptides and endophytes effective against the drug-resistant microbes and target the main drug-resistance determinants (efflux pumps, biofilms, quorum sensing, plasmids, etc.) in these bacterial pathogens. Other exciting topics include applications of nanomaterials in tackling AMR and CRISPR-Cas based precise sequence-specific antimicrobials. This informative book is meant for students and researchers in basic and medical microbiology and biotechnology. It is also useful to public health professionals and industry experts involved in AMR research and related drug-designing.
Antimicrobial Resistance
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Author : World Health Organization
language : en
Publisher:
Release Date : 2014
Antimicrobial Resistance written by World Health Organization and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014 with Medical categories.
Summary report published as technical document with reference number: WHO/HSE/PED/AIP/2014.2.
Water Security Big Data Driven Risk Identification Assessment And Control Of Emerging Contaminants
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Author : Bin Liang
language : en
Publisher: Elsevier
Release Date : 2024-06-12
Water Security Big Data Driven Risk Identification Assessment And Control Of Emerging Contaminants written by Bin Liang and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-06-12 with Science categories.
Water Security: Big Data-Driven Risk Identification, Assessment and Control of Emerging Contaminants contains the latest information on big data-driven risk detection and analysis, risk assessment and environmental health effect, intelligent risk control technologies, and global control strategy of emerging contaminants. First, this book highlights advances and challenges throughout the detection of emerging chemical contaminants (e.g., antimicrobials, microplastics) by sensors or mass spectrometry, as well as emerging biological contaminant (e.g., ARGs, pathogens) by a combination of next- and third-generation sequencing technologies in aquatic environment. Second, it discusses in depth the ecological risk assessment and environmental health effects of emerging contaminants. Lastly, it presents the most up-to-date intelligent risk management technologies.This book shares instrumental global strategy and policy analysis on how to control emerging contaminants. Offering interdisciplinary and global perspectives from experts in environmental sciences and engineering, environmental microbiology and microbiome, environmental informatics and bioinformatics, intelligent systems, and knowledge engineering, this book provides an accessible and flexible resource for researchers and upper level students working in these fields. - Covers the detection, high-throughput analyses, and environmental behavior of the typical emerging chemical and biological contaminants - Focuses on chemical and biological big data driven aquatic ecological risk assessment models and techniques - Highlights the intelligent management and control technologies and policies for emerging contaminants in water environments
Antimicrobial Resistance
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Author : Yashwant Kumar
language : en
Publisher: BoD – Books on Demand
Release Date : 2019-05-02
Antimicrobial Resistance written by Yashwant Kumar and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-05-02 with Medical categories.
The discovery of antibiotics was considered a milestone in health sciences and became the mainstay of antimicrobial therapy to treat and control bacterial infections. However, its utility has subsequently become limited, due to the emergence and spread of antimicrobial resistance among different bacterial species, which has emerged as a global threat. The development and spread of antimicrobial resistance have been attributed to many factors, including indiscriminate use of antibiotics in the healthcare and livestock industries. The present scenario of antibiotic resistance urgently requires interventions in terms of development of newer antimicrobials, evaluation of alternative therapies, and formulation of stringent policies to curb indiscriminate use of antimicrobials. This book highlights the importance and development of antimicrobial resistance in zoonotic, environmental and food bacteria, including the significance of candidate alternative therapies.