Handbook Of Transcription Factor Nf Kappab

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Handbook Of Transcription Factor Nf Kappab

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Author : Sankar Ghosh
language : en
Publisher: CRC Press
Release Date : 2006-10-20

Handbook Of Transcription Factor Nf Kappab written by Sankar Ghosh and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-10-20 with Medical categories.

Recent evidence proving the molecular link between unchecked, chronic inflammation and cancer has implicated the transcription factor NF-kB as a key factor in both inhibiting apoptosis and promoting cell proliferation. Since its initial identification 20 years ago as a simple regulating factor in one small part of the immune response, NF-kB is prov

Encyclopedia Of Biological Chemistry

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Author :
language : en
Publisher: Academic Press
Release Date : 2013-01-08

Encyclopedia Of Biological Chemistry written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-01-08 with Science categories.

The 4-volume Encyclopedia of Biological Chemistry, Second Edition, represents the current state of a dynamic and crucial field of study. The Encyclopedia pulls together over 500 articles that help define and explore contemporary biochemistry, with content experts carefully chosen by the Editorial Board to assure both breadth and depth in its coverage. Editors-In-Chief William J. Lennarz and M. Daniel Lane have crafted a work that proceeds from the acknowledgement that understanding every living process-from physiology, to immunology, and genetics-is impossible without a grasp on the basic chemistry that provides its underpinning. Each article in the work provides an up-to-date snapshot of a given topic, written by experts, as well as suggestions for further readings for students and researcher wishing to go into greater depth. Available on-line via SciVerse ScienceDirect, the functionality of the Encyclopedia will provide easy linking to referenced articles, electronic searching, as well an online index and glossary to aid comprehension and searchability. This 4-volume set, thoroughly up-to-date and comprehensive, expertly captures this fast-moving field Curated by two esteemed editors-in-chief and an illustrious team of editors and contributors, representing the state of the field Suggestions for further readings offer researchers and students avenues for deeper exploration; a wide-ranging glossary aids comprehension

Guide To Signal Pathways In Immune Cells

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Author : E. Nigel Wardle
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-04-21

Guide To Signal Pathways In Immune Cells written by E. Nigel Wardle and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-04-21 with Medical categories.

To read current biomedical science, one has to have a working knowledge of how important effector molecules cause transduction of their signal within cells, altering the control of genes. This work aims to provide that basic knowledge for medical readers. Students of immunology or cell biology will note its relevance. One will learn how platelets, macrophages, neutrophils, T and B lymphocytes and natural killer cells perform their functions and how skin, breast, prostate and colon cancers emerge. The associated diagrams and tables are used to obviate extensive text. Appropriate references to articles and reviews by workers in each field are given so that further consideration can easily be undertaken. We are all at differing stages of our appreciation of immunology and of pat- physiology. Some persons will have a profound background in biochemistry or molecular biology. Others will have a reminiscence of lectures received years ago. Since this work is principally for clinical doctors, the sections that can be avoided at first reading are marked with an asterisk (*). Always proceed line by line and think of associations that you know. Do you feel comfortable with the statement, “Interleukin 6 stimulates glucose uptake in renal proximal tubular cells, and that action is associated with Stat3, PI3K/Akt, MAPKs and NF-kB signal pathways”? If not, please read on.

Molecular Biology A Comprehensive Guide

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Author : Pasquale De Marco
language : en
Publisher: Pasquale De Marco
Release Date : 2025-03-23

Molecular Biology A Comprehensive Guide written by Pasquale De Marco and has been published by Pasquale De Marco this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-03-23 with Science categories.

Journey into the fascinating world of molecular biology with this comprehensive guide, unveiling the secrets of life at its most fundamental level. Discover the intricate interplay between DNA, RNA, and proteins, the building blocks of all living organisms. Delve into the processes of DNA replication, transcription, and translation, understanding how genetic information is stored, expressed, and utilized. Explore the complex mechanisms of gene regulation, uncovering how cells control which genes are turned on or off, and how this intricate dance influences development, disease, and response to environmental cues. Witness the power of genetic engineering, as scientists harness the ability to manipulate DNA to create new organisms, develop life-saving medicines, and address global challenges. Unravel the mysteries of cell signaling and communication, deciphering how cells communicate with each other and their environment, orchestrating complex biological processes. Investigate the molecular basis of disease, gaining insights into the genetic and molecular mechanisms underlying illnesses, and paving the way for novel therapies. Peer into the depths of molecular evolution and phylogenetics, tracing the evolutionary history of species through the analysis of genetic sequences, revealing the interconnectedness of all life on Earth. Explore the vast world of molecular ecology and environmental biology, understanding how organisms interact with their environment at the molecular level, and how molecular biology can contribute to conservation efforts and address environmental issues. From the inner workings of cells to the vastness of ecosystems, this book offers a captivating exploration of molecular biology, providing a deeper understanding of the fundamental principles that govern life. With its clear explanations, engaging examples, and stunning visuals, this book is an invaluable resource for students, researchers, and anyone fascinated by the intricate world of molecular biology. If you like this book, write a review!

The Guide To Investigation Of Mouse Pregnancy

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Author : B. Anne Croy
language : en
Publisher: Academic Press
Release Date : 2013-12-09

The Guide To Investigation Of Mouse Pregnancy written by B. Anne Croy and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-12-09 with Science categories.

The Guide to Investigation of Mouse Pregnancy is the first publication to cover the mouse placenta or the angiogenic tree the mother develops to support the placenta. This much-needed resource covers monitoring of the cardiovascular system, gestational programming of chronic adult disease, epigenetic regulation, gene imprinting, and stem cells. Offering detailed and integrated information on how drugs, biologics, stress, and manipulations impact pregnancy in the mouse model, this reference highlights techniques used to analyze mouse pregnancy. Joining the ranks of much referenced mouse resources, The Guide to Investigation of Mouse Pregnancy is the only manual providing needed content on pregnancy in animal models for translational medicine and research. - Provides instruction on how to collect pre-clinical data on pregnancy in mouse models for eventual use in human applications - Describes the angiogenic tree the mother's uterus develops to support pregnancy and the monitoring of pregnancy-induced cardiovascular changes - Educates readers on placental cell lineages, decidual development including immune cells, epigenetic regulation, gene imprinting, stem cells, birth and lactation - Discusses how stress, environmental toxicants and other manipulations impact upon placental function and pregnancy success

A Laboratory Guide To In Vitro Transcription

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Author : F. Sierra
language : en
Publisher: Birkhäuser
Release Date : 2013-11-21

A Laboratory Guide To In Vitro Transcription written by F. Sierra and has been published by Birkhäuser this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-21 with Social Science categories.

Expert Guide To Rheumatology

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Author : Arthur M. F. Yee
language : en
Publisher: ACP Press
Release Date : 2005

Expert Guide To Rheumatology written by Arthur M. F. Yee and has been published by ACP Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with Medical categories.

This book encompasses erosive inflammatory arthropathies, collagen vascular diseases, vasculitides, infections, and degenerative diseases in one easy-to-use reference. In addition, the final sections cover common symptoms and comorbidities and discuss the latest findings in the pharmacological treatment of inflammatory rheumatic conditions.

A Guide To Human Gene Therapy

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Author : Roland W Herzog
language : en
Publisher: World Scientific
Release Date : 2010-06-18

A Guide To Human Gene Therapy written by Roland W Herzog and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-06-18 with Science categories.

Ever since the birth of molecular biology, the tantalizing possibility of treating disease at its genetic roots has become increasingly feasible. Gene therapy — though still in its infancy — remains one of the hottest areas of research in medicine. Its approach utilizes a gene transfer vehicle ('vector') to deliver therapeutic DNA or RNA to cells of the body in order to rectify the defect that is causing the disease. Successful therapies have been reported in humans in recent years such as cures in boys with severe immune deficiencies. Moreover, gene therapy strategies are being adapted in numerous biomedical laboratories to obtain novel treatments for a variety of diseases and to study basic biological aspects of disease. Correction of disease in animal studies, is steadily gaining ground, highlighting the immense potential of gene therapy in the medical profession.This book will cover topics that are at the forefront of biomedical research such as RNA interference, viral and non-viral gene transfer systems, treatment of hematological diseases and disorders of the central nervous system. Leading experts on the respective vector or disease will contribute the individual chapters and explain cutting-edge technologies. It also gives a broad overview of the most important gene transfer vectors and most extensively studied target diseases. This comprehensive guide is therefore a must-read for anyone in the biotechnology, biomedical or medical industries seeking to further their knowledge in the area of human gene therapy.

Comprehensive Guide To Acne Scars Understanding Treatment And Long Term Management

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Author : Dr. Spineanu Eugenia
language : en
Publisher: Dr. Spineanu Eugenia
Release Date : 2024-07-01

Comprehensive Guide To Acne Scars Understanding Treatment And Long Term Management written by Dr. Spineanu Eugenia and has been published by Dr. Spineanu Eugenia this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-07-01 with Medical categories.

"Comprehensive Guide to Acne Scars: Understanding, Treatment, and Long-term Management" is an extensive compendium dedicated to unraveling the intricacies of acne scarring. This comprehensive treatise navigates through the multifaceted terrain of acne scars, from their inception to effective management strategies, encompassing the latest advancements in the field. This treatise systematically dissects the complexities of acne scars, diving into their classification, etiology, and pathogenesis. It illuminates the interplay of biological factors, inflammatory pathways, and molecular mechanisms that underlie scar formation, offering a profound understanding of their development.

Essential Guide To Neurodegenerative Disorders

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Author : Wael Mohamed
language : en
Publisher: Elsevier
Release Date : 2024-11-24

Essential Guide To Neurodegenerative Disorders written by Wael Mohamed and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-11-24 with Medical categories.

Handbook of Neurodegenerative Disorders: Mechanism, Diagnostic and Therapeutic Advances provides a comprehensive review on the current biomedical studies aimed at identifying the underlying causes of neurodegeneration. This book reviews the most recent developments in molecular and cellular processes altered during neurodegeneration. Divided into four parts, the first covers the mechanism of cell death in neurodegeneration. The second section reviews the recent progress in gene and gene products in neurodegeneration, including Huntington's disease, Parkinson's disease, Friedreich' s ataxia, and spinal muscular atrophy. The final sections cover the current and future diagnostic techniques of neurodegenerative disorders along with therapeutic approaches. - Reviews big data and neurodegeneration disorders, including gene mapping - Examines the structural basis of protein assembly into amyloid filaments in neurodegenerative disease - Covers the progress and challenges of pharmacotherapy of neurodegenerative disorders