Helicases From All Domains Of Life
DOWNLOAD
Download Helicases From All Domains Of Life PDF/ePub or read online books in Mobi eBooks. Click Download or Read Online button to get Helicases From All Domains Of Life book now. This website allows unlimited access to, at the time of writing, more than 1.5 million titles, including hundreds of thousands of titles in various foreign languages. If the content not found or just blank you must refresh this page
Helicases From All Domains Of Life
DOWNLOAD
Author : Renu Tuteja
language : en
Publisher: Academic Press
Release Date : 2018-09-21
Helicases From All Domains Of Life written by Renu Tuteja and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-09-21 with Science categories.
Helicases from All Domains of Life is the first book to compile information about helicases from many different organisms in a single volume. Research in the helicase field has been going on for a long time now, but the completion of so many genomes of these ubiquitous enzymes has made it difficult to keep up with new discoveries. As the huge number of identified DNA and RNA helicases, along with the structural and functional differences among them, make it difficult for the interested scholar to grasp a comprehensive view of the field, this book helps fill in the gaps. Presents updates on the functions and features of helicases across the different kingdoms Begins with a chapter on the evolutionary history of helicases Contains specific chapters on selected helicases of great importance from a biological/applicative point-of-view
The Dna Replication Machinery As Therapeutic Targets
DOWNLOAD
Author : Andrew F. Gardner
language : en
Publisher: Frontiers Media SA
Release Date : 2019-09-19
The Dna Replication Machinery As Therapeutic Targets written by Andrew F. Gardner and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-09-19 with categories.
In all organisms, the DNA replication machinery is responsible for accurate and efficient duplication of the chromosome. Inhibitors of replication proteins are commonly used in anti-cancer and anti-viral therapies. This eBook on “The DNA Replication Machinery as Therapeutic Targets” examines the normal functions of replication proteins as well as strategies to target each step during the replication process including DNA unwinding, DNA synthesis, and DNA damage bypass and repair. Articles discuss current strategies to develop drugs targeting DNA replication proteins as well as future outlooks and needs.
Dna Helicases And Dna Motor Proteins
DOWNLOAD
Author : Maria Spies
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-11-19
Dna Helicases And Dna Motor Proteins written by Maria Spies and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-11-19 with Medical categories.
In recent years, a number of groundbreaking structural and mechanistic studies deepened our understanding of helicase mechanisms and established new approaches for their analyses. Many fundamental mechanistic questions ranging from the mechanism of force generation, mechanochemical coupling to distinct mechanisms by which the same enzyme translocates on DNA removing obstacles, unwinds DNA and/or remodels nucleoprotein complexes, however, remain to be answered. It is even less understood how the helicase motors are incorporated into a wide range of genome maintenance and repair machines. The field has reached a stage when the studies of molecular mechanisms and basic biology of helicases can and shall be integrated with the studies of development, cancer and longevity. The objective of this book is to provide the first systematic overview of structure, function and regulation of DNA helicases and related molecular motors. By integrating the knowledge obtained through the diverse technical approaches ranging from single-molecule biophysics to cellular and molecular biological studies the editors aim to provide a unified view on how helicases function in the cell, are regulated in response to different cellular stresses and are integrated into large macromolecular assemblies to form a complex and adaptive living system.
Metagenomic Systems Biology
DOWNLOAD
Author : Shailza Singh
language : en
Publisher: Springer Nature
Release Date : 2020-12-07
Metagenomic Systems Biology written by Shailza Singh and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-12-07 with Science categories.
The book serves as an amalgamation of knowledge and principles used in the area of systems and synthetic biology, and targets inter-disciplinary research groups. The readers from diversified areas would be benefited by the valuable resources and information available in one book. Microbiome projects with efficient data handling can fuel progress in the area of microbial synthetic biology by providing a ready to use plug and play chassis. Advances in gene editing technology such as the use of tailor made synthetic transcription factors will further enhance the availability of synthetic devices to be applied in the fields of environment, agriculture and health. The different chapters of the book reviews a broad range of topics, including food microbiome in ecology, use of microbiome in personalized medicine, machine learning in biomedicine. The book also describes ways to harness and exploit the incredible amounts of genomic data. The book is not only limited to medicine but also caters to the needs of environmentalists, biochemical engineers etc. It will be of interest to advanced students and researchers in life sciences, computational biology, microbiology and other inter-disciplinary areas.
Advances In Aquatic Invertebrate Stem Cell Research
DOWNLOAD
Author : Loriano Ballarin
language : en
Publisher: MDPI
Release Date : 2022-01-28
Advances In Aquatic Invertebrate Stem Cell Research written by Loriano Ballarin and has been published by MDPI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-28 with Science categories.
This publication is based upon work from COST Action ’16203 MARISTEM Stem cells of marine/aquatic invertebrates: from basic research to innovative applications’, supported by COST (European Cooperation in Science and Technology). COST (European Cooperation in Science and Technology) is a funding agency for research and innovation networks. Our Actions help connect research initiatives across Europe and enable scientists to grow their ideas by sharing them with their peers. This boosts their research, career and innovation. www.cost.eu Aquatic invertebrates represent the largest biodiversity and the widest phylogenetic radiation on Earth, with more than 2 million known species. Up until a few years ago, their use as model organisms in biological research was limited by the paucity of omics data. Recently, the situation has rapidly changed and is still changing. Today, the genomes and various transcriptomes of many aquatic invertebrate species, as well as many recombinant proteins of invertebrate origin, are available. New technologies have revolutionized the available toolbox of research methodologies. This explains the rising interest of researchers in the use of aquatic invertebrates as reliable model organisms. In contrast to the prevalence of diverse oligopotent and unipotent stem cells in vertebrates, aquatic invertebrates (especially non-ecdysozoan invertebrates) exhibit multiple adult cell types with stem cell attributes characterized by multipotency and pluripotency; furthermore, these give rise to cell lineages characteristic of more than a single germ layer, sometimes with somatic and germ line potentials. In addition, unlike vertebrates, aquatic invertebrate adult stem cells are disseminated and widespread inside the animal body, are not associated with a regulatory microenvironment (niche) and do participate in aging and regeneration phenomena. These properties can help us to better understand the processes and phenomena in mammalian stem cell biology, such as natural chimerism and cancer, aging and senescence, immunity and autoimmune responses, which are all difficult to explain or understand in the human context. The COST Action 16203 MARISTEM "Stem cells of marine/aquatic invertebrates: from basic research to innovative applications" started in 2017 with the aim to foster the knowledge of the biology of aquatic invertebrates stem cells and strengthen the European community of researchers on aquatic invertebrate stem cells in order to build innovative ideas relevant to various biomedical disciplines. This book represents one of the deliverables of the Action and collects part of the materials produced during the past 3 years within the network as a tool to disseminate and render available what has been achieved up to now. We hope that this book will be useful to scientists interested in stem cells of non-model organisms, with particular reference to aquatic invertebrates.
Helicase Enzymes Part B
DOWNLOAD
Author :
language : en
Publisher: Academic Press
Release Date : 2022-08-12
Helicase Enzymes Part B written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-08-12 with Science categories.
Methods in Enzymology serial highlights new advances in the field with this new volume presenting interesting chapters. Each chapter is written by an international board of authors. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in Methods in Enzymology serials Updated release includes the latest information on Helicase Enzymes
Molecular Insights Into The Roles Of Rna Helicases During Large Ribosomal Subunit Assembly
DOWNLOAD
Author : Gerald Ryan Aquino
language : en
Publisher:
Release Date : 2021
Molecular Insights Into The Roles Of Rna Helicases During Large Ribosomal Subunit Assembly written by Gerald Ryan Aquino and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021 with categories.
RNA helicases are enzymes present in all domains of life that are important in many aspects of RNA metabolism. They harbor a conserved helicase core that uses the energy of NTP binding and hydrolysis to change affinity to RNA, a biochemical property that provides RNA helicases mechanisms to unwind RNA duplexes. In the last years, there have been multiple lines of evidence that these specialized proteins can also displace proteins bound to RNAs and act as placeholders to promote intermediate RNA structures and folding. These RNA and ribonucleoprotein complex (RNP) remodeling functions underl...
Genetics Of Salt Tolerance In Plants
DOWNLOAD
Author : Showkat Ahmad Ganie
language : en
Publisher: CABI
Release Date : 2024-06-25
Genetics Of Salt Tolerance In Plants written by Showkat Ahmad Ganie and has been published by CABI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-06-25 with Science categories.
Gene expression in cells follows a prescribed pathway that conforms to the Central Dogma; where the genetic information stored in DNA is transcribed into RNA and then expressed into proteins, which influences most plant traits. Plant salt tolerance research is directed towards identifying nucleotide variants that could contribute to tolerant phenotypes. This book comprehensively presents the current state of knowledge on plant salt tolerance through meticulous analysis of the processes operating across the Central Dogma. It provides a detailed account of modulation of gene expression through genome editing systems to achieve crop improvement against salt stress. It also provides state-of-the-art information on advances in breeding technologies of genome selection and accelerated de novo domestication for rapidly improving the salt tolerance of plants for global food security. The book will be of particular value to students and researchers of plant genetics, molecular biology and physiology and those with an interest in salinity and salt tolerance.
The Mechanisms Of Dna Replication
DOWNLOAD
Author : David Stuart
language : en
Publisher: IntechOpen
Release Date : 2013-02-20
The Mechanisms Of Dna Replication written by David Stuart and has been published by IntechOpen this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-02-20 with Medical categories.
DNA replication is a fundamental part of the life cycle of all organisms. Not surprisingly many aspects of this process display profound conservation across organisms in all domains of life. The chapters in this volume outline and review the current state of knowledge on several key aspects of the DNA replication process. This is a critical process in both normal growth and development and in relation to a broad variety of pathological conditions including cancer. The reader will be provided with new insights into the initiation, regulation, and progression of DNA replication as well as a collection of thought provoking questions and summaries to direct future investigations.
Molecular Themes In Dna Replication
DOWNLOAD
Author : Lynne S Cox
language : en
Publisher: Royal Society of Chemistry
Release Date : 2009-10-31
Molecular Themes In Dna Replication written by Lynne S Cox and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-10-31 with Science categories.
DNA replication, the process of copying one double stranded DNA molecule to form two identical copies, is highly conserved at the mechanistic level across evolution. Interesting in its own right as a fascinating feat of biochemical regulation and coordination, DNA replication is at the heart of modern advances in molecular biology. An understanding of the process at both the biological and chemical level is essential to developing new techniques in molecular biology. Insights into the process at the molecular level provide opportunities to modulate and intervene in replication. Rapidly dividing cells need to replicate their DNA prior to division, and targeting components of the replication process is a potentially powerful strategy in cancer treatment. Conversely, ageing may be associated with loss of replication activity and restoring it to cells may moderate some of the diseases associated with old age. Replication is, therefore, fundamental to a huge range of molecular biological and biochemical applications, and provides many potential targets for drug design. The fast pace of replication research, particularly in providing new structural insights, has outdated the majority of available texts. This learned, yet accessible, book contains the latest research written by those conducting it. It examines conserved themes providing a biological background for biochemical, chemical and pharmaceutical studies of this huge and exciting field. Rather than simply "itemising" the replication steps and the proteins involved, replication is tackled from a novel perspective. The book provides logical groupings of processes based upon biochemical similarities. The emphasis on mechanisms and the relationship between structure and function targets the chapters towards biochemists and biological chemists as well as molecular and cell biologists. The book highlights new insights into the replication process, from the assembly of pre-replication complexes, through polymerisation mechanisms, to considering replication in the context of chromatin and chromosomes. It also covers mitochondrial DNA replication, and includes archaeal paradigms, which are proving increasingly relevant to the study of replication in higher eukaryotes. Exciting potential drug targets in DNA replication are discussed, particularly in the context of treating malaria and cancer.