Her2 Positive Breast Cancer
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Her2 Positive Breast Cancer
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Author : Sara Hurvitz
language : en
Publisher: Elsevier Health Sciences
Release Date : 2018-07-26
Her2 Positive Breast Cancer written by Sara Hurvitz and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-07-26 with Medical categories.
Get a quick, expert overview of clinically-focused topics and guidelines that are relevant to testing for HER2, which contributes to approximately 25% of breast cancers today. This concise resource by Drs. Sara Hurvitz, and Kelly McCann consolidates today’s available information on this growing topic into one convenient resource, making it an ideal, easy-to-digest reference for practicing and trainee oncologists.
Handbook Of Her2 Targeted Agents In Breast Cancer
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Author : Ricardo H Alvarez
language : en
Publisher: Springer
Release Date : 2016-05-14
Handbook Of Her2 Targeted Agents In Breast Cancer written by Ricardo H Alvarez and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-05-14 with Medical categories.
This concise handbook provides oncologists and other healthcare providers with crucial updates in the field, including an updated review of the current understanding of the biology of the HER2 pathway, an overview of HER2-testing, and evidence-based discussions of available and emerging HER2-targeted treatment options. An essential clinical text for physicians that screen and treat patients with breast cancer and require an accessible, up-to-date survey of the dynamic treatment landscape.
Handbook Of Her2 Targeted Agents In Breast Cancer
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Author : Ricardo H Alvarez
language : en
Publisher: Springer
Release Date : 2014-05-28
Handbook Of Her2 Targeted Agents In Breast Cancer written by Ricardo H Alvarez and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-05-28 with Medical categories.
Breast cancer is the most frequently diagnosed cancer and the leading cause of cancer death in women worldwide, accounting for nearly a quarter of the total new cancer cases each year. Of these cases, approximately 15–25% overexpress HER2, a transmembrane RTK kinase that is associated with aggressive tumor growth and poor outcomes. However, in the past decade, survival rates of patients with HER-positive breast cancer have significantly improved due to increased screening, HER2 testing, and breakthrough HER2-targeted drug therapies. Handbook of HER2-Targeted Agents in Breast Cancer provides oncologists, primary care physicians, trainees and other healthcare providers with a concise, accessible, and up-to-date survey of the field, including a review of our current understanding of the biology of the HER2 pathway and the rationale for targeting it in early-stage and advanced breast cancer, an overview of HER2-testing, and evidence-based discussions of available HER2-targeted regimens in the adjuvant and metastatic settings.
Drugs For Her 2 Positive Breast Cancer
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Author : Maria Sibilia
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-01-06
Drugs For Her 2 Positive Breast Cancer written by Maria Sibilia and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-01-06 with Medical categories.
Growth factor receptors have long been known to drive malignant transformation and cancer progression. The epidermal growth factor receptor (EGFR, ErbB, HER) system is likely the best described membrane receptor tyrosine kinase family in malignant tumors. With implementation of the growth-inhibitory anti-HER-2 antibody trastuzumab (Herceptin) for the treatment of HER-2-positive advanced metastatic breast cancer, a new era has dawned in the therapy of this malignant disease. Unfortunately, trastuzumab-sensitive cancers invariably develop resistance to the antibody after some time. Recent clinical studies have revealed that these refractory tumors are still responsive to inhibition of the HER receptor family using dual HER-1/-2 inhibitors such as lapatinib (Tykerb/Tyverb). Moreover, a multiplicity of novel, improved irreversibly acting small molecular HER tyrosine kinase inhibitors are in the pipeline of many drug developing companies and are being evaluated in the clinical setting.
Recommendations For Use Of Trastuzumab Herceptin For The Treatment Of Her2 Positive Breast Cancer
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Author : NHMRC National Breast Cancer Centre (Australia)
language : en
Publisher:
Release Date : 2007
Recommendations For Use Of Trastuzumab Herceptin For The Treatment Of Her2 Positive Breast Cancer written by NHMRC National Breast Cancer Centre (Australia) and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with Breast categories.
Breast Cancer Research And Treatment
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Author : Ouissam Al Jarroudi
language : en
Publisher: Springer Nature
Release Date : 2024-01-04
Breast Cancer Research And Treatment written by Ouissam Al Jarroudi and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-01-04 with Medical categories.
This book focuses on innovative treatment options for breast cancer, including surgery, radiotherapy, systemic therapy and of course immunotherapy that is changing outcomes in some aggressive breast cancer histotypes. Subsequent chapters also address the ongoing emerging research in the screening, diagnostics, and management of all subtypes of breast cancers. All current landscapes and future perspectives in each molecular subtype: luminal, HER2-positive, and triple-negative breast cancers are discussed within the different chapters. Breast cancer is still the most common cancer and cause of cancer deaths among women worldwide. The improvement of breast cancer outcome appears to be strictly related to the validation of precise biomarkers that enable us to better select personalized approaches in breast cancer management. The closing chapters deal with the challenges of conducting research in the era of precision medicine for cancer. The book is edited and authored by leading experts in this field and will be of interest for clinicians and scientists alike.
Her2 Inhibitors Advances In Research And Application 2013 Edition
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Author :
language : en
Publisher: ScholarlyEditions
Release Date : 2013-06-21
Her2 Inhibitors Advances In Research And Application 2013 Edition written by and has been published by ScholarlyEditions this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-21 with Medical categories.
HER2 Inhibitors—Advances in Research and Application: 2013 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about ZZZAdditional Research in a concise format. The editors have built HER2 Inhibitors—Advances in Research and Application: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about ZZZAdditional Research in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of HER2 Inhibitors—Advances in Research and Application: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Management Of Breast Cancer In Older Women
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Author : Malcolm W. Reed
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-01-18
Management Of Breast Cancer In Older Women written by Malcolm W. Reed and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-01-18 with Medical categories.
I was looking at Mrs T – all 45 kilos of her – with somewhat puzzled thoughts. I had prescribed her capecitabine at very prudent doses, in view of her 91-year-old kidneys and physiology. She had reduced my treatment even further, “because it was making her tired.” As a result, she was taking a grand total of 500 mg of capecitabine a day. Yet, her metastatic, ER/PR-negative, Her2-positive breast cancer was undoubtedly responding. Her pain was improving and her chest mass was shrinking, as were her lung metastases... What was the secret of that response? Were Mrs T’s kidneys eli- nating even less drug than predicted by her creatinine clearance? Was her sarcopenia altering drug distribution? Was she absorbing more drug than average? Or was her tumor exquisitely sensitive to fluoropyrimidines? “Physicians,” said Voltaire, “pour drugs they know little for diseases they know even less into patients they know no- ing about.” Medicine has made tremendous progress since the eighteenth century. Yet, there are fields where quite a lot remains to be learned. In developed countries, 25% of breast cancers occur in patients aged 75 years and older. Yet, these patients represent only 4% of the population of traditional clinical trials. That ought to let us wonder how relevant data acquired in patients in their 60s are to a nonagenarian. Fortunately, geriatric oncologists have been stepping up to the task and have gen- ated data to help us to treat such patients.
Neo Adjuvant Chemotherapy
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Author : Claude Jacquillat
language : en
Publisher: John Libbey Eurotext
Release Date : 1988
Neo Adjuvant Chemotherapy written by Claude Jacquillat and has been published by John Libbey Eurotext this book supported file pdf, txt, epub, kindle and other format this book has been release on 1988 with Medical categories.
This book presents the Proceedings of the Second International Congress on Neo-Adjuvant Chemotherapy which took place on 19 to 21 February 1988 in Paris.
Her 2
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Author : Robert Bazell
language : en
Publisher: Random House (NY)
Release Date : 1998
Her 2 written by Robert Bazell and has been published by Random House (NY) this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998 with Health & Fitness categories.
The dramatic account of a remarkable new breast cancer drug, from its creation to the moving tales of women whose lives it is saving. The chief correspondent of NBC News, Robert Bazell presents the riveting account of how this drug moved from the lab to the bedside.