High Performance In Memory Genome Data Analysis

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High Performance In Memory Genome Data Analysis

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Author : Hasso Plattner
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-19

High Performance In Memory Genome Data Analysis written by Hasso Plattner and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-19 with Science categories.

Recent achievements in hardware and software developments have enabled the introduction of a revolutionary technology: in-memory data management. This technology supports the flexible and extremely fast analysis of massive amounts of data, such as diagnoses, therapies, and human genome data. This book shares the latest research results of applying in-memory data management to personalized medicine, changing it from computational possibility to clinical reality. The authors provide details on innovative approaches to enabling the processing, combination, and analysis of relevant data in real-time. The book bridges the gap between medical experts, such as physicians, clinicians, and biological researchers, and technology experts, such as software developers, database specialists, and statisticians. Topics covered in this book include - amongst others - modeling of genome data processing and analysis pipelines, high-throughput data processing, exchange of sensitive data and protection of intellectual property. Beyond that, it shares insights on research prototypes for the analysis of patient cohorts, topology analysis of biological pathways, and combined search in structured and unstructured medical data, and outlines completely new processes that have now become possible due to interactive data analyses.

A Course In In Memory Data Management

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Author : Hasso Plattner
language : en
Publisher: Springer
Release Date : 2014-05-28

A Course In In Memory Data Management written by Hasso Plattner and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-05-28 with Business & Economics categories.

Recent achievements in hardware and software development, such as multi-core CPUs and DRAM capacities of multiple terabytes per server, enabled the introduction of a revolutionary technology: in-memory data management. This technology supports the flexible and extremely fast analysis of massive amounts of enterprise data. Professor Hasso Plattner and his research group at the Hasso Plattner Institute in Potsdam, Germany, have been investigating and teaching the corresponding concepts and their adoption in the software industry for years. This book is based on an online course that was first launched in autumn 2012 with more than 13,000 enrolled students and marked the successful starting point of the openHPI e-learning platform. The course is mainly designed for students of computer science, software engineering, and IT related subjects, but addresses business experts, software developers, technology experts, and IT analysts alike. Plattner and his group focus on exploring the inner mechanics of a column-oriented dictionary-encoded in-memory database. Covered topics include - amongst others - physical data storage and access, basic database operators, compression mechanisms, and parallel join algorithms. Beyond that, implications for future enterprise applications and their development are discussed. Step by step, readers will understand the radical differences and advantages of the new technology over traditional row-oriented, disk-based databases. In this completely revised 2nd edition, we incorporate the feedback of thousands of course participants on openHPI and take into account latest advancements in hard- and software. Improved figures, explanations, and examples further ease the understanding of the concepts presented. We introduce advanced data management techniques such as transparent aggregate caches and provide new showcases that demonstrate the potential of in-memory databases for two diverse industries: retail and life sciences.

High Performance In Memory Genome Data Analysis

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Author :
language : en
Publisher:
Release Date : 2014

High Performance In Memory Genome Data Analysis written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014 with categories.

Advanced Information Networking And Applications

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Author : Leonard Barolli
language : en
Publisher: Springer Nature
Release Date : 2021-04-30

Advanced Information Networking And Applications written by Leonard Barolli and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-04-30 with Computers categories.

This book covers the theory, design and applications of computer networks, distributed computing and information systems. Networks of today are going through a rapid evolution, and there are many emerging areas of information networking and their applications. Heterogeneous networking supported by recent technological advances in low-power wireless communications along with silicon integration of various functionalities such as sensing, communications, intelligence and actuations is emerging as a critically important disruptive computer class based on a new platform, networking structure and interface that enable novel, low-cost and high-volume applications. Several of such applications have been difficult to realize because of many interconnections problems. To fulfill their large range of applications, different kinds of networks need to collaborate, and wired and next-generation wireless systems should be integrated in order to develop high-performance computing solutions to problems arising from the complexities of these networks. The aim of the book “Advanced Information Networking and Applications” is to provide latest research findings, innovative research results, methods and development techniques from both theoretical and practical perspectives related to the emerging areas of information networking and applications.

Next Generation Sequencing Data Analysis

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Author : Xinkun Wang
language : en
Publisher: CRC Press
Release Date : 2016-04-06

Next Generation Sequencing Data Analysis written by Xinkun Wang and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-04-06 with Mathematics categories.

A Practical Guide to the Highly Dynamic Area of Massively Parallel SequencingThe development of genome and transcriptome sequencing technologies has led to a paradigm shift in life science research and disease diagnosis and prevention. Scientists are now able to see how human diseases and phenotypic changes are connected to DNA mutation, polymorphi

Real Time Business Intelligence And Analytics

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Author : Malu Castellanos
language : en
Publisher: Springer Nature
Release Date : 2019-10-10

Real Time Business Intelligence And Analytics written by Malu Castellanos and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-10-10 with Computers categories.

This book constitutes the thoroughly refereed conference proceedings of the BIRTE workshops listed below, which were held in in conjunction with VLDB, the International Conference on Very Large Data Bases: 9th International Workshop on Business Intelligence for the Real-Time Enterprise, BIRTE 2015, held in Kohala Coast, Hawaii, in August 2015, 10th International Workshop on Enabling Real-Time Business Intelligence, BIRTE 2016, held in New Delhi, India, in September 2016, 11th International Workshop on Real-Time Business Intelligence and Analytics, BIRTE 2017, held in Munich, Germany, in August 2017. The BIRTE workshop series provides a forum for the discussion and advancement of the science and engineering enabling real-time business intelligence and the novel applications that build on these foundational techniques. The book includes five selected papers from BIRTE 2015; five selected papers from BIRTE 2016; and three selected papers from BIRTE 2017.

High Performance Computing

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Author : Julian M. Kunkel
language : en
Publisher: Springer
Release Date : 2016-06-14

High Performance Computing written by Julian M. Kunkel and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-06-14 with Computers categories.

This book constitutes the refereed proceedings of the 31st International Conference, ISC High Performance 2016 [formerly known as the International Supercomputing Conference] held in Frankfurt, Germany, in June 2016. The 25 revised full papers presented in this book were carefully reviewed and selected from 60 submissions. The papers cover the following topics: Autotuning and Thread Mapping; Data Locality and Decomposition; Scalable Applications; Machine Learning; Datacenters andCloud; Communication Runtime; Intel Xeon Phi; Manycore Architectures; Extreme-scale Computations; and Resilience.

The Digital Patient

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Author : C. D. Combs
language : en
Publisher: John Wiley & Sons
Release Date : 2015-12-11

The Digital Patient written by C. D. Combs and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-12-11 with Mathematics categories.

A modern guide to computational models and constructive simulation for personalized patient care using the Digital Patient The healthcare industry’s emphasis is shifting from merely reacting to disease to preventing disease and promoting wellness. Addressing one of the more hopeful Big Data undertakings, The Digital Patient: Advancing Healthcare, Research, and Education presents a timely resource on the construction and deployment of the Digital Patient and its effects on healthcare, research, and education. The Digital Patient will not be constructed based solely on new information from all the “omics” fields; it also includes systems analysis, Big Data, and the various efforts to model the human physiome and represent it virtually. The Digital Patient will be realized through the purposeful collaboration of patients as well as scientific, clinical, and policy researchers. The Digital Patient: Advancing Healthcare, Research, and Education addresses the international research efforts that are leading to the development of the Digital Patient, the wealth of ongoing research in systems biology and multiscale simulation, and the imminent applications within the domain of personalized healthcare. Chapter coverage includes: The visible human The physiological human The virtual human Research in systems biology Multi-scale modeling Personalized medicine Self-quantification Visualization Computational modeling Interdisciplinary collaboration The Digital Patient: Advancing Healthcare, Research, and Education is a useful reference for simulation professionals such as clinicians, medical directors, managers, simulation technologists, faculty members, and educators involved in research and development in the life sciences, physical sciences, and engineering. The book is also an ideal supplement for graduate-level courses related to human modeling, simulation, and visualization.

Heterogeneous Data Management Polystores And Analytics For Healthcare

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Author : Vijay Gadepally
language : en
Publisher: Springer
Release Date : 2019-03-21

Heterogeneous Data Management Polystores And Analytics For Healthcare written by Vijay Gadepally and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-03-21 with Computers categories.

This book constitutes the refereed post-conference proceedings of International Workshops: Polystores and other Systems for Heterogeneous Data, Poly 2018, and Data Management and Analytics for Medicine and Healthcare, DMAH 2018, in Rio de Janeiro, Brazil, in August 2018, held in conjunction with the 44th International Conference on Very Large Data Bases, VLDB 2018. The 11 regular papers presented together with 2 invited papers and 1 abstract of a keynote talk were carefully reviewed and selected from 16 initial submissions. The Poly 2018 Workshop focus on growing a larger and more diverse research agenda around data system solutions for heterogeneous data. The DMAH 2018 Workshop aims to foster exchange of information and discussions on innovative data management and analytics technologies.

Big Data Analytics In Genomics

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Author : Ka-Chun Wong
language : en
Publisher: Springer
Release Date : 2016-10-24

Big Data Analytics In Genomics written by Ka-Chun Wong and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-10-24 with Computers categories.

This contributed volume explores the emerging intersection between big data analytics and genomics. Recent sequencing technologies have enabled high-throughput sequencing data generation for genomics resulting in several international projects which have led to massive genomic data accumulation at an unprecedented pace. To reveal novel genomic insights from this data within a reasonable time frame, traditional data analysis methods may not be sufficient or scalable, forcing the need for big data analytics to be developed for genomics. The computational methods addressed in the book are intended to tackle crucial biological questions using big data, and are appropriate for either newcomers or veterans in the field.This volume offers thirteen peer-reviewed contributions, written by international leading experts from different regions, representing Argentina, Brazil, China, France, Germany, Hong Kong, India, Japan, Spain, and the USA. In particular, the book surveys three main areas: statistical analytics, computational analytics, and cancer genome analytics. Sample topics covered include: statistical methods for integrative analysis of genomic data, computation methods for protein function prediction, and perspectives on machine learning techniques in big data mining of cancer. Self-contained and suitable for graduate students, this book is also designed for bioinformaticians, computational biologists, and researchers in communities ranging from genomics, big data, molecular genetics, data mining, biostatistics, biomedical science, cancer research, medical research, and biology to machine learning and computer science. Readers will find this volume to be an essential read for appreciating the role of big data in genomics, making this an invaluable resource for stimulating further research on the topic.