High Performance In Memory Genome Data Analysis
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High Performance In Memory Genome Data Analysis
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Author : Hasso Plattner
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-19
High Performance In Memory Genome Data Analysis written by Hasso Plattner and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-19 with Science categories.
Recent achievements in hardware and software developments have enabled the introduction of a revolutionary technology: in-memory data management. This technology supports the flexible and extremely fast analysis of massive amounts of data, such as diagnoses, therapies, and human genome data. This book shares the latest research results of applying in-memory data management to personalized medicine, changing it from computational possibility to clinical reality. The authors provide details on innovative approaches to enabling the processing, combination, and analysis of relevant data in real-time. The book bridges the gap between medical experts, such as physicians, clinicians, and biological researchers, and technology experts, such as software developers, database specialists, and statisticians. Topics covered in this book include - amongst others - modeling of genome data processing and analysis pipelines, high-throughput data processing, exchange of sensitive data and protection of intellectual property. Beyond that, it shares insights on research prototypes for the analysis of patient cohorts, topology analysis of biological pathways, and combined search in structured and unstructured medical data, and outlines completely new processes that have now become possible due to interactive data analyses.
A Course In In Memory Data Management
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Author : Hasso Plattner
language : en
Publisher: Springer
Release Date : 2014-05-28
A Course In In Memory Data Management written by Hasso Plattner and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-05-28 with Business & Economics categories.
Recent achievements in hardware and software development, such as multi-core CPUs and DRAM capacities of multiple terabytes per server, enabled the introduction of a revolutionary technology: in-memory data management. This technology supports the flexible and extremely fast analysis of massive amounts of enterprise data. Professor Hasso Plattner and his research group at the Hasso Plattner Institute in Potsdam, Germany, have been investigating and teaching the corresponding concepts and their adoption in the software industry for years. This book is based on an online course that was first launched in autumn 2012 with more than 13,000 enrolled students and marked the successful starting point of the openHPI e-learning platform. The course is mainly designed for students of computer science, software engineering, and IT related subjects, but addresses business experts, software developers, technology experts, and IT analysts alike. Plattner and his group focus on exploring the inner mechanics of a column-oriented dictionary-encoded in-memory database. Covered topics include - amongst others - physical data storage and access, basic database operators, compression mechanisms, and parallel join algorithms. Beyond that, implications for future enterprise applications and their development are discussed. Step by step, readers will understand the radical differences and advantages of the new technology over traditional row-oriented, disk-based databases. In this completely revised 2nd edition, we incorporate the feedback of thousands of course participants on openHPI and take into account latest advancements in hard- and software. Improved figures, explanations, and examples further ease the understanding of the concepts presented. We introduce advanced data management techniques such as transparent aggregate caches and provide new showcases that demonstrate the potential of in-memory databases for two diverse industries: retail and life sciences.
Real Time Business Intelligence And Analytics
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Author : Malu Castellanos
language : en
Publisher: Springer Nature
Release Date : 2019-10-10
Real Time Business Intelligence And Analytics written by Malu Castellanos and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-10-10 with Computers categories.
This book constitutes the thoroughly refereed conference proceedings of the BIRTE workshops listed below, which were held in in conjunction with VLDB, the International Conference on Very Large Data Bases: 9th International Workshop on Business Intelligence for the Real-Time Enterprise, BIRTE 2015, held in Kohala Coast, Hawaii, in August 2015, 10th International Workshop on Enabling Real-Time Business Intelligence, BIRTE 2016, held in New Delhi, India, in September 2016, 11th International Workshop on Real-Time Business Intelligence and Analytics, BIRTE 2017, held in Munich, Germany, in August 2017. The BIRTE workshop series provides a forum for the discussion and advancement of the science and engineering enabling real-time business intelligence and the novel applications that build on these foundational techniques. The book includes five selected papers from BIRTE 2015; five selected papers from BIRTE 2016; and three selected papers from BIRTE 2017.
Ibm Reference Architecture For High Performance Data And Ai In Healthcare And Life Sciences
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Author : Dino Quintero
language : en
Publisher: IBM Redbooks
Release Date : 2019-09-08
Ibm Reference Architecture For High Performance Data And Ai In Healthcare And Life Sciences written by Dino Quintero and has been published by IBM Redbooks this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-09-08 with Computers categories.
This IBM® Redpaper publication provides an update to the original description of IBM Reference Architecture for Genomics. This paper expands the reference architecture to cover all of the major vertical areas of healthcare and life sciences industries, such as genomics, imaging, and clinical and translational research. The architecture was renamed IBM Reference Architecture for High Performance Data and AI in Healthcare and Life Sciences to reflect the fact that it incorporates key building blocks for high-performance computing (HPC) and software-defined storage, and that it supports an expanding infrastructure of leading industry partners, platforms, and frameworks. The reference architecture defines a highly flexible, scalable, and cost-effective platform for accessing, managing, storing, sharing, integrating, and analyzing big data, which can be deployed on-premises, in the cloud, or as a hybrid of the two. IT organizations can use the reference architecture as a high-level guide for overcoming data management challenges and processing bottlenecks that are frequently encountered in personalized healthcare initiatives, and in compute-intensive and data-intensive biomedical workloads. This reference architecture also provides a framework and context for modern healthcare and life sciences institutions to adopt cutting-edge technologies, such as cognitive life sciences solutions, machine learning and deep learning, Spark for analytics, and cloud computing. To illustrate these points, this paper includes case studies describing how clients and IBM Business Partners alike used the reference architecture in the deployments of demanding infrastructures for precision medicine. This publication targets technical professionals (consultants, technical support staff, IT Architects, and IT Specialists) who are responsible for providing life sciences solutions and support.
Advanced Information Networking And Applications
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Author : Leonard Barolli
language : en
Publisher: Springer Nature
Release Date : 2021-04-30
Advanced Information Networking And Applications written by Leonard Barolli and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-04-30 with Computers categories.
This book covers the theory, design and applications of computer networks, distributed computing and information systems. Networks of today are going through a rapid evolution, and there are many emerging areas of information networking and their applications. Heterogeneous networking supported by recent technological advances in low-power wireless communications along with silicon integration of various functionalities such as sensing, communications, intelligence and actuations is emerging as a critically important disruptive computer class based on a new platform, networking structure and interface that enable novel, low-cost and high-volume applications. Several of such applications have been difficult to realize because of many interconnections problems. To fulfill their large range of applications, different kinds of networks need to collaborate, and wired and next-generation wireless systems should be integrated in order to develop high-performance computing solutions to problems arising from the complexities of these networks. The aim of the book “Advanced Information Networking and Applications” is to provide latest research findings, innovative research results, methods and development techniques from both theoretical and practical perspectives related to the emerging areas of information networking and applications.
Heterogeneous Data Management Polystores And Analytics For Healthcare
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Author : Vijay Gadepally
language : en
Publisher: Springer
Release Date : 2019-03-21
Heterogeneous Data Management Polystores And Analytics For Healthcare written by Vijay Gadepally and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-03-21 with Computers categories.
This book constitutes the refereed post-conference proceedings of International Workshops: Polystores and other Systems for Heterogeneous Data, Poly 2018, and Data Management and Analytics for Medicine and Healthcare, DMAH 2018, in Rio de Janeiro, Brazil, in August 2018, held in conjunction with the 44th International Conference on Very Large Data Bases, VLDB 2018. The 11 regular papers presented together with 2 invited papers and 1 abstract of a keynote talk were carefully reviewed and selected from 16 initial submissions. The Poly 2018 Workshop focus on growing a larger and more diverse research agenda around data system solutions for heterogeneous data. The DMAH 2018 Workshop aims to foster exchange of information and discussions on innovative data management and analytics technologies.
High Performance Computational Methods For Biological Sequence Analysis
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Author : Tieng K. Yap
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
High Performance Computational Methods For Biological Sequence Analysis written by Tieng K. Yap and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Computers categories.
High Performance Computational Methods for Biological Sequence Analysis presents biological sequence analysis using an interdisciplinary approach that integrates biological, mathematical and computational concepts. These concepts are presented so that computer scientists and biomedical scientists can obtain the necessary background for developing better algorithms and applying parallel computational methods. This book will enable both groups to develop the depth of knowledge needed to work in this interdisciplinary field. This work focuses on high performance computational approaches that are used to perform computationally intensive biological sequence analysis tasks: pairwise sequence comparison, multiple sequence alignment, and sequence similarity searching in large databases. These computational methods are becoming increasingly important to the molecular biology community allowing researchers to explore the increasingly large amounts of sequence data generated by the Human Genome Project and other related biological projects. The approaches presented by the authors are state-of-the-art and show how to reduce analysis times significantly, sometimes from days to minutes. High Performance Computational Methods for Biological Sequence Analysis is tremendously important to biomedical science students and researchers who are interested in applying sequence analyses to their studies, and to computational science students and researchers who are interested in applying new computational approaches to biological sequence analyses.
High Performance Computing
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Author : Ponnuswamy Sadayappan
language : en
Publisher: Springer Nature
Release Date : 2020-06-15
High Performance Computing written by Ponnuswamy Sadayappan and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-06-15 with Computers categories.
This book constitutes the refereed proceedings of the 35th International Conference on High Performance Computing, ISC High Performance 2020, held in Frankfurt/Main, Germany, in June 2020.* The 27 revised full papers presented were carefully reviewed and selected from 87 submissions. The papers cover a broad range of topics such as architectures, networks & infrastructure; artificial intelligence and machine learning; data, storage & visualization; emerging technologies; HPC algorithms; HPC applications; performance modeling & measurement; programming models & systems software. *The conference was held virtually due to the COVID-19 pandemic. Chapters "Scalable Hierarchical Aggregation and Reduction Protocol (SHARP) Streaming-Aggregation Hardware Design and Evaluation", "Solving Acoustic Boundary Integral Equations Using High Performance Tile Low-Rank LU Factorization", "Scaling Genomics Data Processing with Memory-Driven Computing to Accelerate Computational Biology", "Footprint-Aware Power Capping for Hybrid Memory Based Systems", and "Pattern-Aware Staging for Hybrid Memory Systems" are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
The Digital Patient
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Author : C. D. Combs
language : en
Publisher: John Wiley & Sons
Release Date : 2015-12-11
The Digital Patient written by C. D. Combs and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-12-11 with Mathematics categories.
A modern guide to computational models and constructive simulation for personalized patient care using the Digital Patient The healthcare industry’s emphasis is shifting from merely reacting to disease to preventing disease and promoting wellness. Addressing one of the more hopeful Big Data undertakings, The Digital Patient: Advancing Healthcare, Research, and Education presents a timely resource on the construction and deployment of the Digital Patient and its effects on healthcare, research, and education. The Digital Patient will not be constructed based solely on new information from all the “omics” fields; it also includes systems analysis, Big Data, and the various efforts to model the human physiome and represent it virtually. The Digital Patient will be realized through the purposeful collaboration of patients as well as scientific, clinical, and policy researchers. The Digital Patient: Advancing Healthcare, Research, and Education addresses the international research efforts that are leading to the development of the Digital Patient, the wealth of ongoing research in systems biology and multiscale simulation, and the imminent applications within the domain of personalized healthcare. Chapter coverage includes: The visible human The physiological human The virtual human Research in systems biology Multi-scale modeling Personalized medicine Self-quantification Visualization Computational modeling Interdisciplinary collaboration The Digital Patient: Advancing Healthcare, Research, and Education is a useful reference for simulation professionals such as clinicians, medical directors, managers, simulation technologists, faculty members, and educators involved in research and development in the life sciences, physical sciences, and engineering. The book is also an ideal supplement for graduate-level courses related to human modeling, simulation, and visualization.
Big Data Management And Processing
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Author : Kuan-Ching Li
language : en
Publisher: CRC Press
Release Date : 2017-05-19
Big Data Management And Processing written by Kuan-Ching Li and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-05-19 with Computers categories.
From the Foreword: "Big Data Management and Processing is [a] state-of-the-art book that deals with a wide range of topical themes in the field of Big Data. The book, which probes many issues related to this exciting and rapidly growing field, covers processing, management, analytics, and applications... [It] is a very valuable addition to the literature. It will serve as a source of up-to-date research in this continuously developing area. The book also provides an opportunity for researchers to explore the use of advanced computing technologies and their impact on enhancing our capabilities to conduct more sophisticated studies." ---Sartaj Sahni, University of Florida, USA "Big Data Management and Processing covers the latest Big Data research results in processing, analytics, management and applications. Both fundamental insights and representative applications are provided. This book is a timely and valuable resource for students, researchers and seasoned practitioners in Big Data fields. --Hai Jin, Huazhong University of Science and Technology, China Big Data Management and Processing explores a range of big data related issues and their impact on the design of new computing systems. The twenty-one chapters were carefully selected and feature contributions from several outstanding researchers. The book endeavors to strike a balance between theoretical and practical coverage of innovative problem solving techniques for a range of platforms. It serves as a repository of paradigms, technologies, and applications that target different facets of big data computing systems. The first part of the book explores energy and resource management issues, as well as legal compliance and quality management for Big Data. It covers In-Memory computing and In-Memory data grids, as well as co-scheduling for high performance computing applications. The second part of the book includes comprehensive coverage of Hadoop and Spark, along with security, privacy, and trust challenges and solutions. The latter part of the book covers mining and clustering in Big Data, and includes applications in genomics, hospital big data processing, and vehicular cloud computing. The book also analyzes funding for Big Data projects.