Hiv 1 Integrase
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Hiv 1 Integrase
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Author : Nouri Neamati
language : en
Publisher: John Wiley & Sons
Release Date : 2011-08-10
Hiv 1 Integrase written by Nouri Neamati and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-08-10 with Science categories.
This book comprehensively covers the mechanisms of action and inhibitor design for HIV-1 integrase. It serves as a resource for scientists facing challenging drug design issues and researchers in antiviral drug discovery. Despite numerous review articles and isolated book chapters dealing with HIV-1 integrase, there has not been a single source for those working to devise anti-AIDS drugs against this promising target. But this book fills that gap and offers a valuable introduction to the field for the interdisciplinary scientists who will need to work together to design drugs that target HIV-1 integrase.
Antiviral Drug Discovery And Development
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Author : Xinyong Liu
language : en
Publisher: Springer Nature
Release Date : 2021-07-13
Antiviral Drug Discovery And Development written by Xinyong Liu and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-07-13 with Medical categories.
This book summarizes state-of-the-art antiviral drug design and discovery approaches starting from natural products to de novo design, and provides a timely update on recently approved antiviral drugs and compounds in advanced clinical development. Special attention is paid to viral infections with a high impact on the world population or highly relevant from the public health perspective (HIV, hepatitis C, influenza virus, etc.). In these chapters, limitations associated with adverse effects and emergence of drug resistance are discussed in detail. In addition to classical antiviral strategies, chapters will be dedicated to discuss the non-classical drug development strategies to block viral infection, for instance, allosteric inhibitors, covalent antiviral agents, or antiviral compounds targeting protein–protein interactions. Finally, current prospects for producing broad-spectrum antiviral inhibitors will be also addressed. The book is distinctive in providing the most recent update in the rapidly evolving field of antiviral therapeutics. Authoritative reviews are written by international scientists well known for their contributions in their topics of research, which makes this book suitable for researchers not only within the antiviral research community but also attractive to a broad audience in the drug discovery field. This book covers molecular structures and biochemical mechanisms mediating the antiviral effects, while discussing various ligand design strategies, which include traditional medicinal chemistry, computational chemistry, and chemical biology approaches. The book provides a comprehensive review of antiviral drug discovery and development approaches, particularly focusing on current innovations and future trends.
The Future Of Hiv 1 Therapeutics
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Author : Bruce E. Torbett
language : en
Publisher: Springer
Release Date : 2015-04-22
The Future Of Hiv 1 Therapeutics written by Bruce E. Torbett and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-04-22 with Medical categories.
This volume thoroughly covers HIV-1 antiretrovirals currently in clinical use, together with their advantages and limitations. HIV-1 inhibitor resistance is discussed in detail, and critical assessments as to what will be required of future antiretrovirals in order to halt viral replication, reduce viral resistance, and alter the state of viral latency are presented. Experts at the forefront of HIV-1 research provide overviews of approaches from the fields of virology, chemical biology and structural biology for obtaining small molecule inhibitors that target viral regulatory and structural components at multiple points in the viral lifecycle. The individual chapters will appeal to scientists and clinicians alike.
Biomaterials For Clinical Applications
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Author : Sujata K. Bhatia
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-10-14
Biomaterials For Clinical Applications written by Sujata K. Bhatia and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-10-14 with Technology & Engineering categories.
Biomaterials for Clinical Applications is organized according to the World Health Organization’s report of the top 11 causes of death worldwide, and lays out opportunities for both biomaterials scientists and physicians to tackle each of these leading contributors to mortality. The introductory chapter discusses the global burden of disease. Each of the subsequent eleven chapters focuses on a specific disease process, beginning with the leading cause of death worldwide, cardiovascular disease. The chapters start with describing diseases where clinical needs are most pressing, and then envisions how biomaterials can be designed to address these needs, instead of the more technologically centered approached favored by most books in the field. This book, then, should appeal to chemical engineers and bioengineers who are designing new biomaterials for drug delivery and vaccine delivery, as well as tissue engineering.
Hiv I Molecular Biology And Pathogenesis Clinical Applications
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Author :
language : en
Publisher: Academic Press
Release Date : 2007-12-14
Hiv I Molecular Biology And Pathogenesis Clinical Applications written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-12-14 with Medical categories.
Although it is one of the most-widely studied viruses, many mysteries still remain about HIV. Covering the latest advances and challenges associated with clinical application of new antiviral drugs and vaccines, this revised edition is a companion to Murad: HIV-1: Molecular Biology and Pathogenesis, Second Edition. Leading investigators in HIV research present a timely picture of the molecular mechanisms which guide HIV-1 expression and replication and provide the most current clinical strategies for combating this virus. The latest developments in HIV-vaccine research New concepts in the discovery and design of novel anti-HIV drugs
Retroviruses
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Author : Reinhard Kurth
language : en
Publisher: Caister Academic Press Limited
Release Date : 2010
Retroviruses written by Reinhard Kurth and has been published by Caister Academic Press Limited this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010 with Science categories.
Leading scientists in the field review the genomics, molecular biology and pathogenesis of these important viruses, comprehensively covering all the recent advances.
Cancer Causing Viruses And Their Inhibitors
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Author : Satya Prakash Gupta
language : en
Publisher: CRC Press
Release Date : 2014-05-16
Cancer Causing Viruses And Their Inhibitors written by Satya Prakash Gupta and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-05-16 with Medical categories.
Cancer-causing viruses, also called oncoviruses, play a key role in the development of certain cancers. They contribute to genetic changes that disrupt the cell cycle machinery, interfering with functions such as cell growth. Cancer-Causing Viruses and Their Inhibitors presents a plethora of research from internationally reputed contributors who di
Frontiers In Clinical Drug Research Hiv
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Author : Atta-ur-Rahman
language : en
Publisher: Bentham Science Publishers
Release Date : 2015-04-02
Frontiers In Clinical Drug Research Hiv written by Atta-ur-Rahman and has been published by Bentham Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-04-02 with Medical categories.
Frontiers in Clinical Drug Research – HIV is an eBook series that brings updated reviews to readers interested in learning about advances in the development of pharmaceutical agents for the treatment of acquired immune deficiency syndrome (AIDS) and other disorders associated with human immunodeficiency virus (HIV) infection. The scope of the eBook series covers a range of topics including the medicinal chemistry and pharmacology of natural and synthetic drugs employed in the treatment of AIDS (including HAART) and resulting complications, and the virology and immunological study of HIV and related viruses. Frontiers in Clinical Drug Research – HIV is a valuable resource for pharmaceutical scientists, clinicians and postgraduate students seeking updated and critically important information for developing clinical trials and devising research plans in HIV/AIDS research. The first volume of this series features 7 chapters that cover a variety of topics including: -Antiretroviral drug development -HIV-1 genomics -HIV drug targets such as ribosomes and HIV Integrase -HAART associated nephrotoxicity
Reviews In Fluorescence 2015
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Author : Chris D. Geddes
language : en
Publisher: Springer
Release Date : 2015-12-17
Reviews In Fluorescence 2015 written by Chris D. Geddes and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-12-17 with Medical categories.
Reviews in Fluorescence 2015, the eighth volume of the book serial from Springer, serves as a comprehensive collection of current trends and emerging hot topics in the field of fluorescence and closely related disciplines. It summarizes the year’s progress in fluorescence and its applications, with authoritative reviews specialized enough to be attractive to professional researchers, yet also appealing to the wider audience of scientists in related disciplines of fluorescence. Reviews in Fluorescence offers an essential reference material for any research lab or company working in the fluorescence field and related areas. All academics, bench scientists, and industry professionals wishing to take advantage of the latest and greatest in the continuously emerging field of fluorescence will find it an invaluable resource.
Viral Genome Replication
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Author : Craig E. Cameron
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-05-28
Viral Genome Replication written by Craig E. Cameron and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-05-28 with Medical categories.
This book provides the first comprehensive review of viral genome replication strategies, emphasizing not only pathways and regulation but also the structure-function, mechanism, and inhibition of proteins and enzymes required for this process.