Viral Genome Replication
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Viral Genome Replication
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Author : Craig E. Cameron
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-05-28
Viral Genome Replication written by Craig E. Cameron and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-05-28 with Medical categories.
This book provides the first comprehensive review of viral genome replication strategies, emphasizing not only pathways and regulation but also the structure-function, mechanism, and inhibition of proteins and enzymes required for this process.
Viral Genome Replication
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Author : Craig E. Cameron
language : en
Publisher: Lulu.com
Release Date :
Viral Genome Replication written by Craig E. Cameron and has been published by Lulu.com this book supported file pdf, txt, epub, kindle and other format this book has been release on with categories.
Replication Of Viral And Cellular Genomes
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Author : Yechiel Becker
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Replication Of Viral And Cellular Genomes written by Yechiel Becker and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Biosynthesis of cellular and viral DNA and RNA has been a major topic in molecular biology and biochemistry. The studies by Arthur Kornberg and his colleagues on the in-vitro synthesis of DNA have opened new avenues to understanding the processes controlling the duplication of the genetic information encoded in the DNA and RNA of bacterial and mammalian cells. Viral nucleic acids are replicated in infected cells (bacterial, plant, and animal) by virus coded enzymes with or without the involvement of proteins and enzymes coded by the host cells. The ability of the virus to replicate its genome within a relatively short period in the infected cell makes it an excellent biological tool for studying the molecular events in nucleic acid replication. Indeed, the identification of a number of virus-coded proteins that participate in the biosynthesis of X174 and SV40 DNA has led to the construction of in-vitro systems for the study of nucleic acid biosynthesis. Similarly, studies on the replication of other phage, animal and plant viruses have provided an insight into the nucleic acid sequences from which DNA synthesis is initiated, as well as the proteins and enzymes that regulate the catalyse biosynthetic processes. Investi gation of the molecular processes involved in the replication of cellular and mitochondrial genomes has gained momentum from the rapid developments in the analyses of viral nucleic acid biosynthesis.
The Molecular Basis Of Viral Replication
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Author : R. Bercoff
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
The Molecular Basis Of Viral Replication written by R. Bercoff and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
the discovery of the "splicing" of the gene transcripts, the list would include the whole molecular genetics of the lambda bacteriophage, the notions of "promotor," "repressor," and "integration," the discovery of the reverse flow of genetic information, the very existence of oncogenes, the S'-terminal "cap" struc ture of eukaryotic mRNAs, ... Electronmicroscopy, ultracentrifugation and tissue culture were the landmarks on the way of the young science. During the past few years, however, a major (and not so silent) revolution took place: recombinant DNA technology with all its might entered in our laboratories, and restriction mapping of cloned genomes and sequencing gels have replaced plaque counting and sucrose gradients. The new techniques have made it possible to "dissect" the entire genome of a virus at the molecular level, and studies that would have been dreamt of just in the mid-seventies became the everyday experiments of our days. With new insight into the structure of viral genomes, and a deeper understanding of the mechanisms that regulate their expression, our view of viruses was bound to change: this volume bears witness to this impressive advance.
Adenovirus Dna
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Author : Walter Doerfler
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Adenovirus Dna written by Walter Doerfler and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Orgn Replication Of Viral Dna
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Author : Albert S. Kaplan
language : en
Publisher: Springer
Release Date : 1982-08-25
Orgn Replication Of Viral Dna written by Albert S. Kaplan and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 1982-08-25 with Science categories.
Dna Viruses
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Author : Alan J. Cann
language : en
Publisher: Oxford University Press
Release Date : 1999-10-21
Dna Viruses written by Alan J. Cann and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999-10-21 with Science categories.
DNA Viruses: A Practical Approach groups together the major experimental methods currently employed to study DNA viruses, from the fundamentals of virus culture to novel techniques such as surface plasmon resonance spectrometry and realtime PCR analysis of drug resistance mutations in clinical isolates. Chapter 1 provides an overview of the extraction, purification and characterizations of virus DNA, but also covers the fundamentals of DNA virus culture. Chapters 2 and 3 describe approaches to the molecular investigation and mutagenesis of DNA virus genomes. Chapter 4 considers DNA virus replication and then chapters 5 & 6 describe methods to study transcription control. Chapters 7 to 9 consider aspects of the pathogenesis of DNA virus infections. The final chapter describes the current technology being applied to the development of DNA virus vectors for gene delivery. This volume will therefore be of interest to all those working on DNA viruses whether in academia, industry or clinical research.
Viral Replication Cycle From Pathogenesis And Immune Response To Diagnosis And Therapy
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Author : Henry Puerta-Guardo
language : en
Publisher: BoD – Books on Demand
Release Date : 2024-03-13
Viral Replication Cycle From Pathogenesis And Immune Response To Diagnosis And Therapy written by Henry Puerta-Guardo and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-03-13 with Medical categories.
Viruses pose a huge burden on public health systems and the economy worldwide. In the case of humans, viruses make up about two-thirds of all new human pathogens. Both DNA and RNA viruses can cause acute, persistent, or latent infections, as they can integrate their genome into the host DNA, such as the endogenous retroviruses, which can be associated with a wide variety of cancers in animals and humans. In recent years, viruses have emerged not only as a health threat but also as a potential alternative for producing new diagnostic tools as well as prophylactic/therapeutic approaches to defeat viral diseases. This book provides a broadly comprehensive series of reviews describing the replication strategies used for both DNA and RNA viruses, their interaction with the host immune system, and their potential role in tumorigenicity and cancer immunotherapy as applied to various viruses of critical relevance for human or animal diseases.
Viral Interactions With The Nucleus
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Author : Erin Joanne Walker
language : en
Publisher: Frontiers Media SA
Release Date : 2017-08-16
Viral Interactions With The Nucleus written by Erin Joanne Walker and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-08-16 with Electronic book categories.
Viruses cause numerous medically important diseases, affecting developing, developed, rich and poor alike. The diseases vary in severity, including chickenpox, smallpox, influenza, shingles, herpes, rabies, polio, Ebola, hanta fever, AIDS and the common cold, amongst others. Regardless of the type of tissue or organ affected, all viruses follow the same basic steps to infect host cells. Once in contact with host cells viruses release their genetic material into the cell followed by genome replication, production of viral proteins, assembly of the virus particle and egress from the infected cell. Viruses disrupt normal host cell processes in order to facilitate their own replication/assembly by re-directing cellular machinery for viral transcription, translation, assembly, release and by inhibiting antiviral responses. Regulated nuclear transport of macromolecules through the nuclear pore complex, the only means of transport across the nuclear membrane, is essential for normal cell function and an effective antiviral response. Many viruses disrupt or exploit the nucleocytoplasmic trafficking pathways in host cells. Cytoplasmic viruses exploit the host cell nucleocytoplasmic trafficking machinery to access nuclear functions and/or disrupt nuclear transport, while several DNA viruses use the trafficking pathways to enable export of their components into the cytoplasm; yet others complete their assembly within the nucleus and use nuclear export pathways to access the cytoplasm. Indeed, the many and varied interactions of viruses and viral proteins with nucleocytoplasmic trafficking components have been invaluable in pathway discovery. Importantly, mounting evidence suggests that these interactions play essential roles in virus replication/assembly and hence may be key to understanding pathophysiology of viral diseases. This Frontiers Research Topic is dedicated to the importance of nucleocytoplasmic trafficking to viral pathogenesis.
Replication Competent Viruses For Cancer Therapy
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Author : Pablo Hernáiz Driever
language : en
Publisher: Karger Medical and Scientific Publishers
Release Date : 2001-01-01
Replication Competent Viruses For Cancer Therapy written by Pablo Hernáiz Driever and has been published by Karger Medical and Scientific Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-01-01 with Medical categories.
This book is the first to summarize the molecular principles of modern viral therapy for cancer. It reviews many of the replication-competent viruses currently being investigated for therapeutic use including herpes simplex virus, adenovirus, reovirus, parvovirus, vaccinia virus and Newcastle disease virus, and demonstrates how this approach is being translated to the clinic. Illustrating how virus-host interactions can be exploited for therapy, this book opens up new and promising perspectives for the treatment of cancer. It is therefore recommended reading for clinical investigators in the field of oncology, virologists, cancer immunologists and scientists working in regulatory agencies.