Hiv Interactions With Host Cell Proteins

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Hiv Interactions With Host Cell Proteins

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Author : Paul Spearman
language : en
Publisher:
Release Date : 2011-03-04

Hiv Interactions With Host Cell Proteins written by Paul Spearman and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-03-04 with categories.

Hiv Interactions With Host Cell Proteins

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Author : Paul Spearman
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-12-11

Hiv Interactions With Host Cell Proteins written by Paul Spearman and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-12-11 with Medical categories.

The study of viruses necessarily involves dissecting the intimate details of cellular pathways. Viruses have often been employed as tools in studying cellular pathways, as was done by early retrovirologists such as Peyton Rous in attempting to understand the mechanism of cellular transformation and oncogenesis. On the other side of the coin, virologists seek to de?ne those cellular elements interacting intimatelywiththeir virus ofinterestinorder to better understand viral replication itself, and in some cases to develop antiviral strategies. It is in the intersection of virology and cell biology that many of us ?nd the most rewarding aspects of our research. When a new discovery yields insights into basic cellular mechanisms and presents new targets for int- vention to ?ght a serious pathogen, the impact can be high and the excitement intense. HIV has been no exception to the rule that viruses reveal many basic aspects of cellular biology. In recent years, in part because of the importance of HIV as a major cause of human suffering, numerous cellular processes have been elucidated through work on processes or proteins of this human retrovirus. The excitement in this ?eld is especially well illustrated by the discovery of new innate means of resisting viral replication, such as the work on APOBEC3G, TRIM5a, and BST-2/ tetherin presented in this volume.

Direct And Indirect Interactions Of Hiv With Host Cells

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Author : Tetsuo Tsukamoto
language : en
Publisher: Frontiers Media SA
Release Date : 2021-12-06

Direct And Indirect Interactions Of Hiv With Host Cells written by Tetsuo Tsukamoto and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-12-06 with Science categories.

Hiv Interactions With Dendritic Cells

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Author : Li Wu
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-09-13

Hiv Interactions With Dendritic Cells written by Li Wu and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-09-13 with Medical categories.

Given rapid research progress and advance of the techniques in studying HIV interactions with host cells and factors, there is a critical need for a book on HIV interactions with DCs. The proposed book will aim for a broad readership to facilitate HIV/AIDS research and provide a practical tool for HIV researchers to continuously address novel questions. Specifically, the editors will summarize the literature in this field and provide critical analysis and future directions. International researchers will be invited as contributors of the book, highlighting authors who have contributed significantly to the field from different angles and aspects of virology, cell biology and immunology, etc.

Manipulation Of The Host Cell By Viral Auxiliary Proteins

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Author : Nadine Laguette
language : en
Publisher: Frontiers Media SA
Release Date : 2015-05-07

Manipulation Of The Host Cell By Viral Auxiliary Proteins written by Nadine Laguette and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-05-07 with Electronic book categories.

Productive HIV infection requires completion of all the steps of the replication cycle, the success of which largely relying on the multiple interactions established by viral proteins with cellular partners. Indeed, cellular and viral fates are intertwined and this interplay may involve rerouting of cellular factors/pathways to the benefit of the viral life cycle. To gain a foothold into host cells, HIV has to take advantage of available cellular factories and overcome the numerous potential blocks opposed to its replication while ensuring cellular survival. Viral auxiliary proteins are a perfect paradigm to illustrate the complexity of the relationship between HIV and its host. Although these accessory proteins are mostly unnecessary for viral replication in permissive cells in vitro, they play a crucial role in regulating viral spread ex vivo in non-permissive cells and in vivo in hosts. Most accessory proteins are pleiotropic and instrumental in the counteraction of restriction factors and proteins involved in innate immune response. Several proteins of the “intrinsic” immune system that detect the presence of the assailant and initiate a subsequent immune response, as well as restriction factors that are directly devoted to arresting the replication cycle at precise steps have been characterized. Despite the numerous cellular mechanisms dedicated to preventing viral replication, HIV is able to efficiently replicate in humans. Indeed, as a master regulator of cellular machineries and processes, not only has HIV evolved strategies to avoid triggering of pattern recognition receptors, but HIV has also elaborated ways to counteract host restriction factors, thereby overcoming the hurdles that oppose efficient replication. This review collection is dedicated to the manipulation of host cells by HIV-1 and HIV-2, with a particular focus on viral accessory proteins.

Retrovirus Cell Interactions

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Author : Leslie Parent
language : en
Publisher: Academic Press
Release Date : 2018-08-09

Retrovirus Cell Interactions written by Leslie Parent and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-08-09 with Medical categories.

Retrovirus-Cell Interactions provides an up-to-date review of the interactions between retroviruses and the cells they infect, offering a comprehensive understanding of how retroviruses hijack cellular factors to facilitate virus replication. Drugs targeting viral enzymes have been developed to treat HIV; the next challenge is to inhibit virus-cell interactions as next generation treatment strategies. Organized according to the retrovirus' replication cycle, this book does not focus exclusively on HIV, but rather includes important findings in other retroviral systems, including animal retroviruses, retrotransposons, and endogenous retroelements to allow broad comparisons on important commonalities and differences. Provides a valuable starting point for people who want to develop a detailed understanding of retroviral replication Includes future-thinking strategies, such as next-generation treatment and anti-retroviral therapeutics Features important commonalities and differences among retroviral systems

Host Cell Molecular Chaperone Interactions With Hiv 1

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Author : Steven R. Bartz
language : en
Publisher:
Release Date : 1995

Host Cell Molecular Chaperone Interactions With Hiv 1 written by Steven R. Bartz and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995 with categories.

Hiv Host Interactions

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Author : Theresa Li-Yun Chang
language : en
Publisher: BoD – Books on Demand
Release Date : 2011-11-02

Hiv Host Interactions written by Theresa Li-Yun Chang and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-11-02 with Medical categories.

HIV remains the major global health threat, and neither vaccine nor cure is available. Increasing our knowledge on HIV infection will help overcome the challenge of HIV/AIDS. This book covers several aspects of HIV-host interactions in vitro and in vivo. The first section covers the interaction between cellular components and HIV proteins, Integrase, Tat, and Nef. It also discusses the clinical relevance of HIV superinfection. The next two chapters focus on the role of innate immunity including dendritic cells and defensins in HIV infection followed by the section on the impact of host factors on HIV pathogenesis. The section of co-infection includes the impact of Human herpesvirus 6 and Trichomonas vaginalis on HIV infection. The final section focuses on generation of HIV molecular clones that can be used in macaques and the potential use of cotton rats for HIV studies.

Mechanisms And Specificity Of Hiv Entry Into Host Cells

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Author : Nejat Düzgünes
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Mechanisms And Specificity Of Hiv Entry Into Host Cells written by Nejat Düzgünes and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.

Proceedings of a workshop held in San Francisco, California, June 19--20, 1989

Hiv Host Interactions

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Author : Theresa Li-Yun Chang
language : en
Publisher: IntechOpen
Release Date : 2011-11-02

Hiv Host Interactions written by Theresa Li-Yun Chang and has been published by IntechOpen this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-11-02 with Medical categories.

HIV remains the major global health threat, and neither vaccine nor cure is available. Increasing our knowledge on HIV infection will help overcome the challenge of HIV/AIDS. This book covers several aspects of HIV-host interactions in vitro and in vivo. The first section covers the interaction between cellular components and HIV proteins, Integrase, Tat, and Nef. It also discusses the clinical relevance of HIV superinfection. The next two chapters focus on the role of innate immunity including dendritic cells and defensins in HIV infection followed by the section on the impact of host factors on HIV pathogenesis. The section of co-infection includes the impact of Human herpesvirus 6 and Trichomonas vaginalis on HIV infection. The final section focuses on generation of HIV molecular clones that can be used in macaques and the potential use of cotton rats for HIV studies.