Retrovirus Cell Interactions
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Retrovirus Cell Interactions
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Author : Leslie Parent
language : en
Publisher: Academic Press
Release Date : 2018-08-09
Retrovirus Cell Interactions written by Leslie Parent and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-08-09 with Medical categories.
Retrovirus-Cell Interactions provides an up-to-date review of the interactions between retroviruses and the cells they infect, offering a comprehensive understanding of how retroviruses hijack cellular factors to facilitate virus replication. Drugs targeting viral enzymes have been developed to treat HIV; the next challenge is to inhibit virus-cell interactions as next generation treatment strategies. Organized according to the retrovirus' replication cycle, this book does not focus exclusively on HIV, but rather includes important findings in other retroviral systems, including animal retroviruses, retrotransposons, and endogenous retroelements to allow broad comparisons on important commonalities and differences. Provides a valuable starting point for people who want to develop a detailed understanding of retroviral replication Includes future-thinking strategies, such as next-generation treatment and anti-retroviral therapeutics Features important commonalities and differences among retroviral systems
Cellular Factors Involved In Early Steps Of Retroviral Replication
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Author : John A.T. Young
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Cellular Factors Involved In Early Steps Of Retroviral Replication written by John A.T. Young and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
The articles in this volume provide a comprehensive overview of our current understanding of the roles played by cellular factors in the early steps of retroviral replication. A better understanding of these functions will provide critical new insights into retrovirus-host cell interactions and is likely to prove useful for the future development of effective antiretroviral therapies.
Interactions Between Retroviruses And Herpesviruses
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Author : Hsing-Jien Kung
language : en
Publisher: World Scientific
Release Date : 1994
Interactions Between Retroviruses And Herpesviruses written by Hsing-Jien Kung and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994 with Medical categories.
Retroviruses and herpesviruses are two important human pathogens. Together, they occupy one of the most important places in modern Medical Virology. Coinfections of these two viruses in the same individuals are frequently observed, especially in patients afflicted with AIDS. Potential consequences of such interactions include the exacerbation of the disease, changing of the disease courses and the release of new viruses, etc. An understanding of the underlying mechanism is important, but, thus far, few insights have been gained. The present monograph, arranged in eight chapters, is intended to provide an updated and concise review of recent works regarding the molecular and cellular mechanisms of such interactions. The topics covered range from transcriptional regulation, receptor modulation, genetic recombination, to AIDS and oncogenesis. Human immunodeficiency virus, avian leukosis virus, reticuloendotheliosis virus, herpes simplex virus, cytomegalovirus, herpesvirus-6 and Marek's disease virus are among the viruses discussed. The contributing authors are among the leaders in this field and are responsible for many of the original discoveries presented. This should serve as a valuable research and teaching reference for both beginning and advanced researchers in virology and oncology.
Retroviruses
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Author : John M. Coffin
language : en
Publisher: CSHL Press
Release Date : 1997
Retroviruses written by John M. Coffin and has been published by CSHL Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997 with Electronic books categories.
For over 25 years the study of retroviruses has underpinned much of what is known about information transfer in cells and the genetic and biochemical mechanisms that underlie cell growth and cancer induction. Emergent diseases such as AIDS and adult T-cell lymphoma have widened even further the community of investigators directly concerned with retroviruses, a development that has highlighted the need for an integrated understanding of their biology and their unique association with host genomes. This remarkable volume satisfies that need. Written by a group of the field's most distinguished investigators, rigorously edited to provide a seamless narrative, and elegantly designed for clarity and readability, this book is an instant classic that demands attention from scientists and physicians studying retroviruses and the disorders in which they play a role.
Cellular Factors Involved In Early Steps Of Retroviral Replication
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Author : John A T Young
language : en
Publisher:
Release Date : 2003-07-23
Cellular Factors Involved In Early Steps Of Retroviral Replication written by John A T Young and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-07-23 with categories.
Morphogenesis And Maturation Of Retroviruses
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Author : Hans-Georg Kräusslich
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Morphogenesis And Maturation Of Retroviruses written by Hans-Georg Kräusslich and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Retroviruses arguably belong to the most fascinating of all viruses because of their unusual and highly efficient mode of replication involving reverse transcription and integration of the viral genome and a complex system of transcriptional and post transcriptional regulatory mechanisms. The importance of ret roviruses as human and animal pathogens has also enhanced scientific and medical interest in this diverse group of viruses and has spurred an intensive search for novel and improved antiviral agents. More recently, analysis of retroviral replication and in particular understanding the formation and composition of the virus particle has received additional attention because of the promise of retroviral vectors as vehicles for human somatic gene therapy. Many recent advances have been made in our understanding of the molecular mechanisms governing as sembly and release of infectious retrovirus particles. This book attempts to summarize these recent developments and to provide an overview of our current knowledge on retrovirus particle formation. The individual chapters of the book deal with specific steps in the pathway of retroviral morphogenesis and maturation, starting at the time when the components of the virus have been synthesized within the infected cell and ending once the infectious virion has been released from the cell. An introductory chapter provides a comparative description of the structure and morphology of various retroviruses.
Transacting Functions Of Human Retroviruses
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Author : Irvin S.Y. Chen
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Transacting Functions Of Human Retroviruses written by Irvin S.Y. Chen and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
The coding domains of simple retrovirus genomes direct the synthesis of virion proteins. Complex retroviral genomes generate in addition to virion proteins regulatory transacting proteins that are translated from multiple spliced messenger RNAs and fulfill important functions in the virus life cycle. All human retroviruses have such complex genomes. The transacting proteins of these pathogens are attractive targets for therapeutic intervention because they are viral specific, are essential for efficient virus replication and may be mediators of viral pathogenicity. In summarizing the current knowledge on the regulatory transacting proteins of human retroviruses this volume makes an important contribution toward the control of virus disease.
Retroviral Proteases
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Author : Lawrence C. Kuo
language : en
Publisher: Gulf Professional Publishing
Release Date : 1994-09-22
Retroviral Proteases written by Lawrence C. Kuo and has been published by Gulf Professional Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994-09-22 with Medical categories.
Methods included in this volume apply to the expression and characterization of retroviral proteases and their inhibitor/substrate design.
Human Retroviruses
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Author : Bryan Cullen
language : en
Publisher: Oxford University Press
Release Date : 1993
Human Retroviruses written by Bryan Cullen and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993 with Gene Expression Regulation. categories.
The first book to specifically cover the molecular biology of retroviruses - of immense importance since the high profile of HIV. International contributors provide detailed reviews of the latest knowledge. An excellent text for both medical and non-medical researchers, it also serves as an illuminating introduction for scientists active in other areas.
The Control Of Human Retrovirus Gene Expression
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Author : B. Robert Franza
language : en
Publisher: CSHL Press
Release Date : 1988
The Control Of Human Retrovirus Gene Expression written by B. Robert Franza and has been published by CSHL Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1988 with Health & Fitness categories.