Hla And Disease Associations


Hla And Disease Associations
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Hla And Disease Associations


Hla And Disease Associations
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Author : J.L. Tiwari
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Hla And Disease Associations written by J.L. Tiwari and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.


The human leukocyte antigen (HLA) or tissue types are the products of a rapidly developing field of knowledge within the last 20 years. In the early stages of the research many investigators suspected the existence of a complex series of transplantation antigens, but it was widely believed that these antigens would not be well-defined even in this century. Yet in the last two decades as many as 124 different HLA antigens determined by at least 7 very closely linked genes located on the short arm of chromosome 6 have been identified and subsequently agreed upon by an international nomenclature committee. 1 Extensive international collaboration fueled by the potential clinical application of these antigens to clinical transplantation has advanced the field rapidly. There were nine inter national histocompatibility workshops held during this period. Although iden tification of HLA antigens was of primary clinical importance in transplantation 2 and of great basic interest in human genetics and anthropology, a rather un expected bonus has been the determination that HLA antigens are associated with disease susceptibility to a greater extent than any other known genetic marker in man. In the past, many genetic polymorphisms have been suspected to be associated with diseases. The most extensively studied markers are blood groups, enzymes, and serum proteins. A comprehensive account of published studies, totalling approximately 1,000, of these markers is available in a book by Mourant et al.



Hla And Disease Associations


Hla And Disease Associations
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Author : Jawahar L. Tiwari
language : en
Publisher:
Release Date : 1985

Hla And Disease Associations written by Jawahar L. Tiwari and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1985 with Antigènes HLA - Utilisation diagnostique categories.




Hla In Health And Disease


Hla In Health And Disease
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Author : Robert Lechler
language : en
Publisher: Academic Press
Release Date : 2000-05-09

Hla In Health And Disease written by Robert Lechler and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-05-09 with Medical categories.


This comprehensive and definitive work succeeds and expands on the highly successful HLA and Disease published in 1994. This new edition has been updated, redesigned and reorganised into three sections making it an invaluable reference. The introductory section summarises current knowledge on the structure, function, genetics and evolution of the HLA system. It clarifies its complex and ever changing nomenclature and discusses the mechanisms underlying disease associations with HLA alleles. The second section deals with the importance of HLA in the context of different clinical specialities. Individual chapters describe the association between HLA polymorphism and each disease. The final section features chapters on current laboratory practice in histocompatibility and tissue typing. HLA in Health and Disease is essential reading for basic and clinical researchers working in immunology and immunogenetics, transplantation medicine and autoimmunity. It will also be of interest to anyone in the fields of rheumatology, diabetology, nephrology, allergy, dermatology, neurology, endocrinology, cancer biology, respiratory medicine, haematology, molecular biology and biochemistry. Key Features Structure, function and genetics of HLA HLA nomenclature Evolution of HLA polymorphisms HLA associations in arthritis and rheumatology, renal disease, neurology, diabetes and endocrinology, gastroenterology, respiratory disease, ophthalmology, infections, dermatology and psychiatry HLA and organ transplantation Serological and PCR-based methods in HLA typing Cellular techniques in testing histocompatibility Edited and written by an international panel of experts in the field



Hla And Disease


Hla And Disease
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Author : Werner E. Braun
language : en
Publisher: CRC Press
Release Date : 2019-07-23

Hla And Disease written by Werner E. Braun and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-07-23 with Science categories.


This book discusses the topic of the HLA antigen system. Chapters discuss topics such as; animal studies, the possible mechanisms of HLA and disease associations, statistical and genetic considerations, the clinical use of HLA typing, as well as the current status of HLA and disease associations.



Hla And Disease An Issue Of The Clinics In Laboratory Medicine


Hla And Disease An Issue Of The Clinics In Laboratory Medicine
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Author : Julio Delgado
language : en
Publisher: Elsevier Health Sciences
Release Date : 2018-11-16

Hla And Disease An Issue Of The Clinics In Laboratory Medicine written by Julio Delgado and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-11-16 with Medical categories.


This issue of Clinics in Laboratory Medicine, edited by Drs. Julio Delgado and Eszter Lazar-Molnar, will focus on HLA and Disease. Topics include, but are not limited to, The potential impact of NGS in HLA and disease association studies, HLA typing by NGS, HLA Antibody Testing: Evolution and Challenges, Diversity of killer cell immunoglobulin-like receptors and disease, Technical Aspects of Crossmatching in Transplantation, HLA Markers in Celiac Disease, HLA Associations in Drug Hypersensitivity Reactions, HLA in BMT, Post-transplant monitoring, HLA epitope matching in transplantation, and Molecular Testing in Post-Transplant Monitoring.



Hla And Disease


Hla And Disease
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Author : Braun
language : en
Publisher: CRC Press
Release Date : 2017-12-13

Hla And Disease written by Braun and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-12-13 with categories.


This book discusses the topic of the HLA antigen system. Chapters discuss topics such as; animal studies, the possible mechanisms of HLA and disease associations, statistical and genetic considerations, the clinical use of HLA typing, as well as the current status of HLA and disease associations.



Hla Disease Associations


Hla Disease Associations
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Author : Christine Therese Stier
language : en
Publisher:
Release Date : 1978

Hla Disease Associations written by Christine Therese Stier and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1978 with HLA histocompatibility antigens categories.




Hla And Disease


Hla And Disease
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Author : William E. Braun
language : en
Publisher:
Release Date : 1979

Hla And Disease written by William E. Braun and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1979 with Medical categories.




Hla And Disease


Hla And Disease
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Author : Robert Lechler
language : en
Publisher:
Release Date : 1994

Hla And Disease written by Robert Lechler and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994 with Medical categories.


This text describes the genetics and products of the HLA region and their relationship to diseases including diabetes, rheumatoid arthritis and SLE. The statistical principles relevant to the design and interpretation of HLA and disease studies are presented in simple and accessible language.



Hla Et Maladies


Hla Et Maladies
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Author : Jean Dausset
language : en
Publisher: Editions Inserm
Release Date : 1976

Hla Et Maladies written by Jean Dausset and has been published by Editions Inserm this book supported file pdf, txt, epub, kindle and other format this book has been release on 1976 with Medical categories.