Human Developmental Neurotoxicology
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Human Developmental Neurotoxicology
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Author : David C. Bellinger
language : en
Publisher: CRC Press
Release Date : 2006-04-06
Human Developmental Neurotoxicology written by David C. Bellinger and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-04-06 with Medical categories.
This reference describes the most recent developments in the design, execution, and interpretation of human developmental neurotoxicology studies. Assessing critical issues and controversies in the field, this guide focuses on dose-response/effect relationships and explores challenges in the measurement of exposure to different types of chemicals, including selected metals, organic pollutants, pesticides, and recreational and therapeutic drugs.
Developmental Neurotoxicology
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Author : G Jean Harry
language : en
Publisher: CRC Press
Release Date : 1994-07-13
Developmental Neurotoxicology written by G Jean Harry and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994-07-13 with Medical categories.
Developmental Neurotoxicology addresses a number of basic principles underlying the vulnerability of the developing nervous system to environmental toxicant exposure. Evidence of functional alterations, induced at levels of chemical exposure that fail to produce structural teratological alterations, indicates that the evaluation of the functional capacity of exposed animals may indeed offer a sensitive evaluation of developmental toxicity. The contributing authors discuss the basic principles of development in structure and functional components and present information covering various methodological approaches, as well as evidence for the value of examining the developing nervous system for environmentally induced perturbations. The final chapter covers how this type of data is used to evaluate human risk potential.
Handbook Of Developmental Neurotoxicology
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Author : William Slikker, Jr.
language : en
Publisher: Academic Press
Release Date : 2018-01-04
Handbook Of Developmental Neurotoxicology written by William Slikker, Jr. and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-01-04 with Science categories.
Handbook of Developmental Neurotoxicology, Second Edition, provides a comprehensive view of the fundamental aspects of neurodevelopment, the pathways and agents that affect them, relevant clinical syndromes, and risk assessment procedures for developmental neurotoxicants. The editors and chapter authors are internationally recognized experts whose collaboration heralds a remarkable advance in the field, bridging developmental neuroscience with the principles of neurotoxicology. The book features eight new chapters with newly recruited authors, making it an essential text for students and professionals in toxicology, neurotoxicology, developmental biology, pharmacology, and neuroscience. Presents a comprehensive, up-to-date resource on developmental neurotoxicology with updated chapters from the first edition Contains new chapters that focus on subjects recent to the field Includes well-illustrated material, with diagrams, charts, and tables Contains compelling case studies and chapters written by world experts
Reviews In Environmental Health 1994
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Author :
language : en
Publisher:
Release Date : 1994
Reviews In Environmental Health 1994 written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994 with Developmental neurophysiology categories.
Human Developmental Neurotoxicity
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Author : Gary E. R. Hook
language : en
Publisher:
Release Date : 1994-02-01
Human Developmental Neurotoxicity written by Gary E. R. Hook and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994-02-01 with categories.
Covers the potential neurotoxic effects of chemicals on the developing central nervous system (CNS), which has increased, as evidence has linked exposure to chemicals & drugs with long-term changes in the CNS. Papers: environmental neurotoxic illness: research for prevention; vulnerable periods & processes during CNS development; vulnerability of the developing brain to thyroid abnormalities: environmental insults to the thyroid system; an animal model of learning in developing neurotoxicity; assessment of developing toxicity: neuropsychological batteries; developing neurotoxicity induced by therapeutic & illicit drugs; & children & toxic substances: confronting a major public health challenge.
Developmental Neurotoxicology
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Author : G Jean Harry
language : en
Publisher: CRC Press
Release Date : 1994-07-13
Developmental Neurotoxicology written by G Jean Harry and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994-07-13 with Medical categories.
Developmental Neurotoxicology addresses a number of basic principles underlying the vulnerability of the developing nervous system to environmental toxicant exposure. Evidence of functional alterations, induced at levels of chemical exposure that fail to produce structural teratological alterations, indicates that the evaluation of the functional capacity of exposed animals may indeed offer a sensitive evaluation of developmental toxicity. The contributing authors discuss the basic principles of development in structure and functional components and present information covering various methodological approaches, as well as evidence for the value of examining the developing nervous system for environmentally induced perturbations. The final chapter covers how this type of data is used to evaluate human risk potential.
Developmental Neurotoxicology Research
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Author : Cheng Wang
language : en
Publisher: John Wiley & Sons
Release Date : 2011-04-12
Developmental Neurotoxicology Research written by Cheng Wang and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-04-12 with Science categories.
This book describes how systems biology, pharmacogenomic and behavioral approaches, as applied to neurodevelopmental toxicology, provide a structure to arrange information in a biological model. Authors review and discuss approaches that can be used as effective tools to dissect mechanisms underlying pharmacological and toxicological phenomena associated with the exposure to drugs or environmental toxicants during development. This book presents cross-cutting research tools and animal models, along with applications to the studies associated with potential anesthetic-induced developmental neurotoxicity; the developmental basis of adolescent or adult onset of disease; risk assessment of methyl mercury and its effects on neurodevelopment; challenges in the field to identify environmental factors of relevance to autism; and the strategy and progress of epilepsy research.
Human Developmental Toxicants
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Author : James L. Schardein
language : en
Publisher: CRC Press
Release Date : 2006-08-15
Human Developmental Toxicants written by James L. Schardein and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-08-15 with Medical categories.
Presenting the first database of its kind, this unique reference illustrates the relationships between the chemistry and developmental toxicity of a number of important pharmaceuticals and industrial toxicants. Human Developmental Toxicants contains up-to-date and concise information on the chemical structures, properties, and biological activities
Alternative Methods In Neurotoxicology
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Author :
language : en
Publisher: Elsevier
Release Date : 2023-06-08
Alternative Methods In Neurotoxicology written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-06-08 with Science categories.
Alternative Methods in Neurotoxicology, Volume Nine, the latest release in this series, provides an overview of important in vitro and non-vertebrate animal models available to study the neurotoxicity of a range of toxicants of occupational and environmental relevance. Chapters in this new release include Evaluation of mitochondrial function in neurotoxicology using alternative models, Planarians as a model to study neurotoxic agents, Role of Drosophila melanogaster in neurotoxicology studies: Responses to different harmful substances, Neurotoxicology of metals and metallic nanoparticles in Caenorhabditis elegans, Neurotoxicology of environmental toxicants using Caenorhabditis elegans as a model, Nauphoeta cinerea as an emerging model in neurotoxicology, and more. Other chapters cover Human Neural Stem Cells in Developmental Neurotoxicology: Current Scenario and Future Prospects, Use of Drosophila melanogaster for advances in developmental neurotoxicology studies, 3D neurospheres and neurotoxicity of organophosphorus and TCE, Genetic factors in methylmercury-induced neurotoxicity: what we have learned from Caenorhabditis elegans models, and more. Give an up-to-date about the utilization of popular invertebrates (Drosophila melanogaster and Caenorhabditis elegans) in neurotoxicology Brings concise information on emerging invertebrate models in neurotoxicology (from basic to environmental approaches) Presents updates on the in vitro exploitation of human stem cell in developmental neurotoxicology
Handbook Of Neurotoxicology
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Author : Edward J. Massaro
language : en
Publisher: Springer Science & Business Media
Release Date : 2002-03-20
Handbook Of Neurotoxicology written by Edward J. Massaro and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-03-20 with Medical categories.
N eurotoxicology is a broad and burgeoning field of research. Its growth in recent years can be related, in part, to increased interest in and concern with the fact that a growing number of anthropogenic agents with neurotoxic potential, including pesticides, 1ead, mercury, and the polytypic byproducts of combustion and industrial production, continue to be spewed into and accumulate in the environment. In addition, there is great interest in natural products, including toxins, as sources of therapeutic agents. Indeed, it is well known that many natural toxins ofbroadly differing structure, produced or accumulated for predatory or defensive purposes, and toxic agents, accumulated incidentalIy by numerous species, function to perturb nervous tissue. Components of some of these toxins have been shown to be useful therapeutic agents and/or research reagents. Unfor of some neurotoxicants of anthropogenic ori tunately, the environmental accumulation gin, expecialIy pesticides and metals, has resulted in incidents ofhuman poisoning, some of epidemic proportion, and high levels of morbidity and mortality. Furthermore, an increasing incidence of neurobehavioral disorders, some with baffling symptoms, is confronting clinicians. It is not clear whether this is merely the re suit of increased vigi lance and/or improved diagnostics or a consequence of improved health care. In any case, the role of exposure to environmental and occupational neurotoxicants in the etiology of these phenomena, as well as neurodegenerative diseases, is coming under increasing scrutiny and investigation.