Human Variability In Response To Chemical Exposures Measures Modeling And Risk Assessment
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Human Variability In Response To Chemical Exposures Measures Modeling And Risk Assessment
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Author : David A. Eckerman
language : en
Publisher: CRC Press
Release Date : 2019-12
Human Variability In Response To Chemical Exposures Measures Modeling And Risk Assessment written by David A. Eckerman and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-12 with categories.
and for those interested in toxic effects of chemicals on humans, Human Variability in Response to Chemical Exposures: Measures, Modeling, and Risk Assessment recognizes and addresses the increasing awareness that individual biological differences be reflected when assessing human health risks associated with exposure to chemicals. Eight original manuscripts, commissioned by the ILSI Risk Science Institute, address the evidence for variability in human response to chemicals associated with reproductive and developmental effects, effects on the nervous system and lungs, and cancer. Their reports convey both the current state of scientific understanding of response variability and the genetic basis for such observations. This book recognizes that understanding of variability in response is critical in accounting for interindividual variability in susceptibility and, hence, risk, if the regulatory community and others are expected to characterize human health risks associated with exposure to chemicals. Models for incorporating measures of response variability in the risk assessment process are critically reviewed and illustrated with published data. This authoritative work indicates that, in the case of certain chemicals and in the context of certain specific toxic effects, we have considerable ability to predictively and quantitatively characterize human variability, but, in the majority of cases, our ability to do so is limited. If we improve both quantity and quality of information available on response variability and increase our understanding of target tissue dosimetry, we should be better able to account for variability in human susceptibility to the toxic effects of chemicals.
Human Variability In Response To Chemical Exposures Measures Modeling And Risk Assessment
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Author : David A. Neumann
language : en
Publisher: CRC Press
Release Date : 1998-08-25
Human Variability In Response To Chemical Exposures Measures Modeling And Risk Assessment written by David A. Neumann and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998-08-25 with Medical categories.
and for those interested in toxic effects of chemicals on humans, Human Variability in Response to Chemical Exposures: Measures, Modeling, and Risk Assessment recognizes and addresses the increasing awareness that individual biological differences be reflected when assessing human health risks associated with exposure to chemicals. Eight original manuscripts, commissioned by the ILSI Risk Science Institute, address the evidence for variability in human response to chemicals associated with reproductive and developmental effects, effects on the nervous system and lungs, and cancer. Their reports convey both the current state of scientific understanding of response variability and the genetic basis for such observations. This book recognizes that understanding of variability in response is critical in accounting for interindividual variability in susceptibility and, hence, risk, if the regulatory community and others are expected to characterize human health risks associated with exposure to chemicals. Models for incorporating measures of response variability in the risk assessment process are critically reviewed and illustrated with published data. This authoritative work indicates that, in the case of certain chemicals and in the context of certain specific toxic effects, we have considerable ability to predictively and quantitatively characterize human variability, but, in the majority of cases, our ability to do so is limited. If we improve both quantity and quality of information available on response variability and increase our understanding of target tissue dosimetry, we should be better able to account for variability in human susceptibility to the toxic effects of chemicals.
Human Variability In Response To Chemical Exposures
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Author : David A. Neumann
language : en
Publisher: International Life Science Inst
Release Date : 1998
Human Variability In Response To Chemical Exposures written by David A. Neumann and has been published by International Life Science Inst this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998 with Medical categories.
and for those interested in toxic effects of chemicals on humans, Human Variability in Response to Chemical Exposures: Measures, Modeling, & Risk Assessment recognizes & addresses the increasing awareness that individual biological differences be reflected when assessing human health risks associated with exposure to chemicals. Eight original manuscripts, commissioned by the ILSI Risk Science Institute, address the evidence for variability in human response to chemicals associated with reproductive & developmental effects, effects on the nervous system & lungs, & cancer. Their reports convey both the current state of scientific understanding of response variability & the genetic basis for such observations. This book recognizes that understanding of variability in response is critical in accounting for interindividual variability in susceptibility and, hence, risk, if the regulatory community & others are expected to characterize human health risks associated with exposure to chemicals. Models for incorporating measures of response variability in the risk assessment process are critically reviewed & illustrated with published data. This authoritative work indicates that, in the case of certain chemicals & in the context of certain specific toxic effects, we have considerable ability to predictively & quantitatively characterize human variability, but, in the majority of cases, our ability to do so is limited. If we improve both quantity & quality of information available on response variability & increase our understanding of target tissue dosimetry, we should be better able to account for variability in human susceptibility to the toxic effects of chemicals.
Human Variability In Response To Chemical Exposures Measures Modeling And Risk Assessment
DOWNLOAD
Author : David A. Eckerman
language : en
Publisher: CRC Press
Release Date : 1998-08-25
Human Variability In Response To Chemical Exposures Measures Modeling And Risk Assessment written by David A. Eckerman and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998-08-25 with Medical categories.
and for those interested in toxic effects of chemicals on humans, Human Variability in Response to Chemical Exposures: Measures, Modeling, and Risk Assessment recognizes and addresses the increasing awareness that individual biological differences be reflected when assessing human health risks associated with exposure to chemicals. Eight original manuscripts, commissioned by the ILSI Risk Science Institute, address the evidence for variability in human response to chemicals associated with reproductive and developmental effects, effects on the nervous system and lungs, and cancer. Their reports convey both the current state of scientific understanding of response variability and the genetic basis for such observations. This book recognizes that understanding of variability in response is critical in accounting for interindividual variability in susceptibility and, hence, risk, if the regulatory community and others are expected to characterize human health risks associated with exposure to chemicals. Models for incorporating measures of response variability in the risk assessment process are critically reviewed and illustrated with published data. This authoritative work indicates that, in the case of certain chemicals and in the context of certain specific toxic effects, we have considerable ability to predictively and quantitatively characterize human variability, but, in the majority of cases, our ability to do so is limited. If we improve both quantity and quality of information available on response variability and increase our understanding of target tissue dosimetry, we should be better able to account for variability in human susceptibility to the toxic effects of chemicals.
Principles For Modelling Dose Response For The Risk Assessment Of Chemicals
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Author : World Health Organization
language : en
Publisher: World Health Organization
Release Date : 2009
Principles For Modelling Dose Response For The Risk Assessment Of Chemicals written by World Health Organization and has been published by World Health Organization this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009 with Medical categories.
"Published under the joint sponsorship of the United Nations Environment Programme, the International Labour Organisation and the World Health Organization, and produced within the framework of the Inter-Organization Programme for the Sound Management of Chemicals."
Chemical Specific Adjustment Factors For Interspecies Differences And Human Variability
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Author : International Program on Chemical Safety
language : en
Publisher: World Health Organization
Release Date : 2005-12-31
Chemical Specific Adjustment Factors For Interspecies Differences And Human Variability written by International Program on Chemical Safety and has been published by World Health Organization this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-12-31 with Law categories.
Published under the joint sponsorship of the WHO, the ILO and the UNEP and produced within the framework of the Inter-Organization Programme for the Sound Management of Chemicals. On cover: IPCS: International Programme on Chemical Safety
Public Health Risk Assessment For Human Exposure To Chemicals
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Author : K. Asante-Duah
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Public Health Risk Assessment For Human Exposure To Chemicals written by K. Asante-Duah and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
In fact, with the control and containment of most infectious conditions and diseases of the past millennium having been achieved in most developed countries, and with the resultant increase in life expectancies, much more attention seems to have shifted to degenerative health problems. Many of the degenerative health conditions have been linked to thousands of chemicals regularly encountered in human living and occupational/work environments. It is important, therefore, that human health risk assessments are undertaken on a consistent basis - in order to determine the potential impacts of the target chemicals on public health.
Public Health Risk Assessment For Human Exposure To Chemicals
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Author : Kofi Asante-Duah
language : en
Publisher: Springer
Release Date : 2017-06-22
Public Health Risk Assessment For Human Exposure To Chemicals written by Kofi Asante-Duah and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-06-22 with Medical categories.
This book provides a concise, yet comprehensive overview of the many facets relating to human health risk assessments in relation to chemical exposure problems. It presents some very important tools and methodologies that can be used to address chemical exposure and public health risk management problems in a consistent, efficient, and cost-effective manner. On the whole, the book represents a collection and synthesis of the principal elements of the risk assessment process that may be used to more effectively address issues pertaining to human exposures to chemicals found in modern societies. This also includes an elaboration of pertinent risk assessment concepts and techniques/methodologies for performing human health risk assessments. Written for both the novice and the experienced, the subject matter of this book is an attempt at offering a simplified and systematic presentation of public health risk assessment methods and application tools – all these facilitated by a layout that will carefully navigate the user through the major processes involved. A number of illustrative example problems are interspersed throughout the book, in order to help present the book in an easy-to-follow, pragmatic manner.
Information Resources In Toxicology
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Author : P.J. Bert Hakkinen
language : en
Publisher: Elsevier
Release Date : 2000-01-10
Information Resources In Toxicology written by P.J. Bert Hakkinen and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-01-10 with Medical categories.
Information Resources in Toxicology, Third Edition is a sourcebook for anyone who needs to know where to find toxicology information. It provides an up-to-date selective guide to a large variety of sources--books, journals, organizations, audiovisuals, internet and electronic sources, and more. For the Third Edition, the editors have selected, organized, and updated the most relevant information available. New information on grants and other funding opportunities, physical hazards, patent literature, and technical reports have also been added. This comprehensive, time-saving tool is ideal for toxicologists, pharmacologists, drug companies, testing labs, libraries, poison control centers, physicians, legal and regulatory professionals, and chemists. Serves as an all-in-one resource for toxicology information New edition includes information on publishers, grants and other funding opportunities, physical hazards, patent literature, and technical reports Updated to include the latest internet and electronic sources, e-mail addresses, etc. Provides valuable data about the new fields that have emerged within toxicological research; namely, the biochemical, cellular, molecular, and genetic aspects
Ieh Report On Variability And Susceptibility In Human Response To Occupational Exposure To Chemicals In The Uk
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Author : Medical Research Council (Great Britain). Institute for Environment and Health
language : en
Publisher:
Release Date : 2002
Ieh Report On Variability And Susceptibility In Human Response To Occupational Exposure To Chemicals In The Uk written by Medical Research Council (Great Britain). Institute for Environment and Health and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Environmental toxicology categories.