Imaging And Functional Imaging Of The Lung

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Imaging And Functional Imaging Of The Lung
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Author : Joseph M. Reinhardt
language : en
Publisher: Frontiers Media SA
Release Date : 2024-04-16
Imaging And Functional Imaging Of The Lung written by Joseph M. Reinhardt and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-04-16 with Science categories.
Imaging techniques have been used for decades to detect anomalies, study organ function and for diagnostic purposes. Advances in imaging techniques and image processing as well as a wider availability of lung imaging is providing an increasing amount of data and new insights into lung structure and function and their alterations in common lung diseases. Functional imaging biomarkers have the potential to better characterize individual patient phenotypes, predict disease trajectories, and help personalize therapy. The wealth of new data also confronts us with new challenges in terms of identifying, quantifying, deciphering, and standardizing image-based parameters pertaining to regional lung function.
Functional Imaging Of The Chest
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Author : Hans-Ulrich Kauczor
language : en
Publisher: Springer Science & Business Media
Release Date : 2004
Functional Imaging Of The Chest written by Hans-Ulrich Kauczor and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with Medical categories.
For a long time, imaging of the chest was based on the use of either radiography, demonstrating lung morphology, or scintigraphy, looking at lung function. However, as a result of recent developments in CT and MRI technology it is now possible to perform dedicated investigations of different aspects of lung function, such as ventilation, perfusion, gas exchange, and respiratory mechanics. This volume, written by acknowledged experts in the field, provides a well-illustrated and comprehensive review of these novel approaches to functional imaging of the chest. It will be of great assistance to all who are establishing such strategies in the research or clinical arenas for the diagnostic work-up and follow-up of patients with lung diseases.
Pulmonary Functional Imaging
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Author : Yoshiharu Ohno
language : en
Publisher: Springer Nature
Release Date : 2020-12-11
Pulmonary Functional Imaging written by Yoshiharu Ohno and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-12-11 with Medical categories.
This book reviews the basics of pulmonary functional imaging using new CT and MR techniques and describes the clinical applications of these techniques in detail. The intention is to equip readers with a full understanding of pulmonary functional imaging that will allow optimal application of all relevant techniques in the assessment of a variety of diseases, including COPD, asthma, cystic fibrosis, pulmonary thromboembolism, pulmonary hypertension, lung cancer and pulmonary nodule. Pulmonary functional imaging has been promoted as a research and diagnostic tool that has the capability to overcome the limitations of morphological assessments as well as functional evaluation based on traditional nuclear medicine studies. The recent advances in CT and MRI and in medical image processing and analysis have given further impetus to pulmonary functional imaging and provide the basis for future expansion of its use in clinical applications. In documenting the utility of state-of-the-art pulmonary functional imaging in diagnostic radiology and pulmonary medicine, this book will be of high value for chest radiologists, pulmonologists, pulmonary surgeons, and radiation technologists.
Functional Imaging Of The Chest
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Author : Hans-Ulrich Kauczor
language : en
Publisher: Springer
Release Date :
Functional Imaging Of The Chest written by Hans-Ulrich Kauczor and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on with Medical categories.
For a long time, imaging of the chest was based on the use of either radiography, demonstrating lung morphology, or scintigraphy, looking at lung function. However, as a result of recent developments in CT and MRI technology it is now possible to perform dedicated investigations of different aspects of lung function, such as ventilation, perfusion, gas exchange, and respiratory mechanics. This volume, written by acknowledged experts in the field, provides a well-illustrated and comprehensive review of these novel approaches to functional imaging of the chest. It will be of great assistance to all who are establishing such strategies in the research or clinical arenas for the diagnostic work-up and follow-up of patients with lung diseases.
Functional Imaging Of The Lungs Using Magnetic Resonance Imaging Of Inert Fluorinated Gases
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Author : Marcus Couch
language : en
Publisher:
Release Date : 2016
Functional Imaging Of The Lungs Using Magnetic Resonance Imaging Of Inert Fluorinated Gases written by Marcus Couch and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016 with categories.
Fluorine-19 (19F) magnetic resonance imaging (MRI) of the lungs using inhaled inert fluorinated gases can potentially provide high quality anatomical and functional images of the lungs. This technique is able to visualize the distribution of the inhaled gas, similar to hyperpolarized (HP) helium-3 (3He) and xenon-129 (129Xe) MRI. Inert fluorinated gases have the advantages of being nontoxic, abundant, and inexpensive compared to HP gases. Due to the high gyromagnetic ratio of 19F, there is sufficient thermally polarized signal for imaging, and averaging within a single breath-hold is possible due to short longitudinal relaxation times. Since inert fluorinated gases do not need to be hyperpolarized prior to their use in MRI, this eliminates the need for an expensive polarizer and expensive isotopes. Inert fluorinated gas MRI of the lungs has been studied extensively in animals since the 1980s, and more recently in healthy volunteers and patients with lung diseases. This thesis focused on the development of static breath-hold inert fluorinated gas MR imaging techniques, as well as the development functional imaging biomarkers in humans and animal models of pulmonary disease. Optimized ultrashort echo time (UTE) 19F MR imaging was performed in healthy volunteers, and images from different gas breathing techniques were quantitatively compared. 19F UTE MR imaging was then quantitatively compared to 19F gradient echo imaging in both healthy volunteers and in a resolution phantom. A preliminary comparison to HP 3He MR imaging is also presented, along with preliminary 19F measurements of the apparent diffusion coefficient (ADC) and iv gravitational gradients of ventilation in healthy volunteers. The potential of inert fluorinated gas MRI in detecting pulmonary diseases was further explored by performing ventilation mapping in animal models of inflammation and fibrosis. Overall, interest in pulmonary 19F MRI of inert fluorinated gases is increasing, and numerous sites around the world are now interested in developing this technique. This work may help to demonstrate that inert fluorinated gas MRI has the potential to be a viable clinical imaging modality that can provide useful information for the diagnosis and management of chronic respiratory diseases.
Mri Of The Lung
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Author : Hans-Ulrich Kauczor
language : en
Publisher: Springer
Release Date : 2018-11-28
Mri Of The Lung written by Hans-Ulrich Kauczor and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-11-28 with Medical categories.
This book provides a comprehensive overview of how to use MRI for the imaging of lung disease. Special emphasis is placed on routine applications and the clinical impact of MRI in each setting. In addition, current technological developments are reviewed and information presented on dedicated applications of MRI in preclinical and translational research, clinical trials, and specialized institutions. During the past two decades, significant advances in the technology have enabled MRI to enter and mature in the clinical arena of chest imaging. Standard protocols are now readily available on MR scanners, and MRI is recommended as the first- or second-line imaging modality for a variety of lung diseases, not limited to cystic fibrosis, pulmonary hypertension, and lung cancer. The benefits and added value of MRI originate from its ability to both visualize lung structure and provide information on different aspects of lung function, such as perfusion, respiratory motion, ventilation, and gas exchange. On this basis, novel quantitative surrogates for lung function and therapy control (imaging biomarkers) are generated. The second edition of MRI of the Lung has been fully updated to take account of recent advances. It is written by an internationally balanced team of renowned authors representing all major groups in the field.
Imaging
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Author : R. Graham Barr
language : en
Publisher: European Respiratory Society
Release Date : 2016-03-01
Imaging written by R. Graham Barr and has been published by European Respiratory Society this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-03-01 with Medical categories.
Imaging is key to the screening and diagnosis of many respiratory conditions. It is also an area of significant debate, particularly with regard to questions surrounding safety and overuse. This Monograph will be of interest to pulmonologists in all areas of respiratory medicine. The book covers two main areas: imaging methodology and safety; and imaging use in specific respiratory conditions. Chapters will include: safety issues in CT and MRI, MRI methods, radionuclide imaging, chest radiography, COPD, cystic fibrosis, asthma, lung cancer, pulmonary hypertension, and much more.
Pulmonary Drug Delivery
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Author : Ali Nokhodchi
language : en
Publisher: John Wiley & Sons
Release Date : 2015-05-18
Pulmonary Drug Delivery written by Ali Nokhodchi and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-05-18 with Science categories.
Drug therapy via inhalation route is at the cutting edge of modern drug delivery research. There has been significant progress on the understanding of drug therapy via inhalation products. However, there are still problems associated with their formulation design, including the interaction between the active pharmaceutical ingredient(s) (APIs), excipients and devices. This book seeks to cover some of the most pertinent issues and challenges of such formulation design associated with industrial production and desirable clinical outcome. The chapter topics have been selected with a view to integrating the factors that require consideration in the selection and design of device and formulation components which impact upon patient usability and clinical effectiveness. The challenges involved with the delivery of macromolecules by inhalation to both adult and pediatric patients are also covered. Written by leading international experts from both academia and industry, the book will help readers (formulation design scientists, researchers and post-graduate and specialized undergraduate students) develop a deep understanding of key aspects of inhalation formulations as well as detail ongoing challenges and advances associated with their development.
Molecular Imaging Of The Lungs
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Author : Daniel Schuster
language : en
Publisher: CRC Press
Release Date : 2005-05-23
Molecular Imaging Of The Lungs written by Daniel Schuster and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-05-23 with Medical categories.
This authoritative reference reviews current and emerging molecular imaging modalities that are expected to impact the detection and treatment of lung diseases in the near future-including applications in gene expression and inflammation imaging; the imaging of pulmonary cytokine regulation; the molecular imaging of angiogenesis, the airways, and l
Functional Mri
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Author : Ramachandran Ramani
language : en
Publisher: Oxford University Press
Release Date : 2019-01-23
Functional Mri written by Ramachandran Ramani and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-01-23 with Medical categories.
Functional MRI: Basic Principles and Emerging Clinical Applications provides an overview of the basic principles of fMRI for clinicians with minimal knowledge of the imaging technique and its research potential and clinical applications. The text is divided into two parts, with Section I covering the primary signal measured in fMRI (BOLD), the correlation between neuronal activity and the BOLD signal, and how the data is analyzed and interpreted in fMRI. Section II explores applications of fMRI in cognitive neuroscience and common psychiatric disorders, surgical planning in neurosurgery, anesthesia and the intensive care unit, and more. Timely and highly accessible, this book is a valuable resource for researchers and clinicians interested in understanding what fMRI is, how it works, and its applications.