Immediate Early Genes And Inducible Transcription Factors In Mapping Of The Central Nervous System Function And Dysfunction
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Immediate Early Genes And Inducible Transcription Factors In Mapping Of The Central Nervous System Function And Dysfunction
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Author : Leszek Kaczmarek
language : en
Publisher: Gulf Professional Publishing
Release Date : 2002
Immediate Early Genes And Inducible Transcription Factors In Mapping Of The Central Nervous System Function And Dysfunction written by Leszek Kaczmarek and has been published by Gulf Professional Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Brain mapping categories.
This book brings together information about the most widely studied IEG/ITF involved in a variety of neuronal activation. Written by a prominent group of authors, it attempts to unravel the complexity of the phenomena of gene expression in the central nervous system.
Immediate Early Genes And Inducible Transcription Factors In Mapping Of The Central Nervous System Function And Dysfunction
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Author : L. Kaczmarek
language : en
Publisher: Gulf Professional Publishing
Release Date : 2002-07-01
Immediate Early Genes And Inducible Transcription Factors In Mapping Of The Central Nervous System Function And Dysfunction written by L. Kaczmarek and has been published by Gulf Professional Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-07-01 with Medical categories.
That molecular neurobiology has become a dominant part of neuroscience research can be credited to the discovery of inducible gene expression in the brain and spinal cord. This volume deals with genes, whose expression patterns in the vertebrate central nervous system were the first to be revealed and then the most extensively investigated over the last 15 years. Immediate early genes (IEG) and their protein products, especially those acting as regulators of transcription (inducible transcription factors, ITF) have proven to be very valuable tools in functional neuroanatomy and neurophysiology, as they are rapidly and transiently induced in specific neurons in response to various modes of stimulation. Thus, they have been used to map neuronal populations selectively responsive to a variety of conditions, such as sensory and learning experience, electrical stimulation of specific circuits, seizures, and neurodegeneration.This single volume, written by the most prominent authors in the field, brings together for the first time information about the most widely studied IEG/ITF in a whole variety of phenomena of neuronal activation. It starts with a critical appraisal of the technologies employed for the studies on gene, protein, and transcription factor activity in the nervous system. Several chapters present exhaustive examples of expression patterns of the ITF in "vocal" avian brain, mammalian brain sensory regions, areas involved in regulation of circadian rhythms, and the spinal cord. The next parts cover functional and regular aspects of individual IEG/ITF expression: c-fos in learning and memory, c-jun and others in neuropathology and neuronal stress responses, Elk-1, egr family, and CREB in neuronal plasticity and learning. This volume will be useful as a major reference on this topic. Furthermore, it attempts to unravel the seemingly overwhelming complexity of the phenomena of gene expression in the central nervous system.
Immediate Early Genes In Sensory Processing Cognitive Performance And Neurological Disorders
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Author : Raphael Pinaud
language : en
Publisher: Springer Science & Business Media
Release Date : 2006-11-22
Immediate Early Genes In Sensory Processing Cognitive Performance And Neurological Disorders written by Raphael Pinaud and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-11-22 with Medical categories.
This book provides a compilation of the most up-to-date literature on the topic of immediate early genes (IEGs). It reviews and details experiments and theories that challenge the reader to expand their view on how IEG research is currently being used to advance our understanding of static and active brain circuits. In addition, the book explores roles of IEGs in clinical neuropathology.
Brain Damage And Repair
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Author : T. Herdegen
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-05-08
Brain Damage And Repair written by T. Herdegen and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-05-08 with Medical categories.
Brain Damage and Repair aims to attract the interest of neuroscientists and clinical neurologists by building a novel bridge from molecular research to clinical therapy. This novel approach reveals the functional features of neurons and glia in the particular context of vulnerability and self-protection, intracellular properties and extracellular matrix. Arising from this platform, this volume unfolds the molecular and systemic processes underlying migration disorders, axonal injury, repair and regeneration. Comprehensive chapters on neurological diseases, such as M. Alzheimer, M. Parkinson, ALS, stroke or trauma, take this knowledge, apply it at the clinical level to provide a basis for novel therapeutic strategies. Brain Damage and Repair is completed with chapters on imaging techniques, viral gene transfer or legal international handling of stem cell transfer and patents of DNA/proteins.
Plasticity In The Visual System
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Author : Raphael Pinaud
language : en
Publisher: Springer Science & Business Media
Release Date : 2006-04-04
Plasticity In The Visual System written by Raphael Pinaud and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-04-04 with Medical categories.
Mechanisms of neural plasticity enable the encoding and memorization of information based on sensory inputs and can be harnessed to partially restore function after CNS assault such as stroke or head trauma. In the present book, experts from the field of visual system plasticity describe and evaluate the evidence for neural mechanisms proposed to underlie CNS plasticity in the major divisions of the brain dedicated to visual processing, the retina, sub-cortical structures and cortex. We present studies from a wide variety of disciplines that range from molecular biology to neurophysiology and computer modeling. Leading investigators discuss their own work, and integrate this research with colleagues from other specializations. The book points out future applications for this research including clinical uses and engineering within the biomedical sciences. This book is an exciting and thought provoking read for all levels of science enthusiast interested in the physical basis of learning and cognition.
Neurobehavioral Genetics
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Author : Byron C. Jones
language : en
Publisher: CRC Press
Release Date : 2006-08-30
Neurobehavioral Genetics written by Byron C. Jones and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-08-30 with Medical categories.
A complete background to concepts and principles of behavioral genetics, Neurobehavioral Genetics: Methods and Applications, Second Edition features a broad spectrum of the most current techniques in neurobehavioral genetics in a single source. International researchers incorporate several new developments in the field, including: De
Immediate Early Genes And Inducible Transcription Factors In Mapping Of The Central Nervous System Function And Dysfunction
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Author :
language : en
Publisher:
Release Date : 2002
Immediate Early Genes And Inducible Transcription Factors In Mapping Of The Central Nervous System Function And Dysfunction written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Central nervous system categories.
Metallochemistry Of Neurodegeneration
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Author : Henryk Kozlowski
language : en
Publisher: Royal Society of Chemistry
Release Date : 2007-10-31
Metallochemistry Of Neurodegeneration written by Henryk Kozlowski and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-10-31 with Science categories.
Bioinorganic chemistry has a cross disciplinary approach, applying the principles of chemistry to biological systems. Metallochemistry of Neurodegeneration: Biological, Chemical and Genetic Aspects discusses the rapidly developing area of metals in the nervous system and their role in neurodegenerative disease, such as Alzheimer's, Parkinson's and prion diseases. Written by leading experts in their fields, each chapter combines elements of genetics, biochemistry and biological inorganic chemistry in its discussion. The book highlights the differences in pathologies of neurodegenerative diseases but also discusses the mechanistic similarities. Sections include: metal ions and prion diseases; metal ions and Alzheimer disease; manganese in brain functioning; metal involvement in Parkinson disease; Cu-Zn superoxide dismutase and familial amyotrophic lateral sclerosis. This book will appeal to both chemists and biologists at the post graduate and research level.
Neuroproteomics
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Author : Oscar Alzate
language : en
Publisher: CRC Press
Release Date : 2009-10-26
Neuroproteomics written by Oscar Alzate and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-10-26 with Medical categories.
In this, the post-genomic age, our knowledge of biological systems continues to expand and progress. As the research becomes more focused, so too does the data. Genomic research progresses to proteomics and brings us to a deeper understanding of the behavior and function of protein clusters. And now proteomics gives way to neuroproteomics as we beg
Behavioral Neurobiology Of Birdsong
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Author : Harris Philip Zeigler
language : en
Publisher:
Release Date : 2004
Behavioral Neurobiology Of Birdsong written by Harris Philip Zeigler and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with Nature categories.
An overview of findings in the bird song system that have had a major impact on neuroscience research, and have fundamentally altered our concepts of brain function. The 32 papers constitute the proceedings of a conference on The Behavioural Neurobiology of Bird Song, held in New York in 2002.