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Immediate Early Genes In Sensory Processing Cognitive Performance And Neurological Disorders

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Immediate Early Genes In Sensory Processing Cognitive Performance And Neurological Disorders

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Author : Raphael Pinaud
language : en
Publisher: Springer Science & Business Media
Release Date : 2006-11-22

Immediate Early Genes In Sensory Processing Cognitive Performance And Neurological Disorders written by Raphael Pinaud and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-11-22 with Medical categories.

This book provides a compilation of the most up-to-date literature on the topic of immediate early genes (IEGs). It reviews and details experiments and theories that challenge the reader to expand their view on how IEG research is currently being used to advance our understanding of static and active brain circuits. In addition, the book explores roles of IEGs in clinical neuropathology.

The Role Of Immediate Early Genes In Neuropsychiatric Illness

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Author : Amelia L. Gallitano
language : en
Publisher: Frontiers Media SA
Release Date : 2020-03-30

The Role Of Immediate Early Genes In Neuropsychiatric Illness written by Amelia L. Gallitano and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-03-30 with categories.

Brain Aromatase Estrogens And Behavior

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Author : Jacques Balthazart
language : en
Publisher: Oxford University Press
Release Date : 2012-09-21

Brain Aromatase Estrogens And Behavior written by Jacques Balthazart and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-09-21 with Psychology categories.

It is well known that the class of steroid hormones known as estrogens have powerful effects on organs related to reproduction such as the uterus and the breast. What is less well known is that estrogens also profoundly modulate brain function and behavior. Estrogens, such as estradiol, can occur in brain as the result of ovarian secretion of the hormone into the blood that then finds its way to the brain. In male vertebrates, the testes secrete androgens, such as testosterone, into the blood and this class of steroid hormones can be converted into estrogens in the brain via the action of the enzyme aromatase which is expressed in the male brain in many species. Finally estradiol can be synthesized de novo from cholesterol as it has been shown in a variety of species that all the enzymes required to synthesize estrogens are expressed in the brain. This book collects chapters by experts in the field that considers, how estradiol is synthesized in the brain and what its effects are on a variety of behaviors. Special attention is paid to the enzyme aromatase that is distributed in discrete regions of the brain and is highly regulated in a sex specific and seasonal specific manner. Recently it has become clear that estrogens can act in the brain at two very different time scales, one is rather long lasting (days to weeks) and involves the modulation of gene transcription by the hormone-receptor complex. A second mode of action is much quicker and involves the action of estrogens on cell membranes that can result in effects on second messenger systems and ultimately behavior within minutes. Thus this book highlights novel views of estrogen action that are still under-appreciated namely that estrogens have significant effects on the male brain and that they can act on two very different times scales. This volume will be of interest to both basic researchers and clinicians interested in the action of estrogens.

Neuroproteomics

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Author : Oscar Alzate
language : en
Publisher: CRC Press
Release Date : 2009-10-26

Neuroproteomics written by Oscar Alzate and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-10-26 with Medical categories.

In this, the post-genomic age, our knowledge of biological systems continues to expand and progress. As the research becomes more focused, so too does the data. Genomic research progresses to proteomics and brings us to a deeper understanding of the behavior and function of protein clusters. And now proteomics gives way to neuroproteomics as we beg

Rapid Eye Movement Sleep

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Author : Birendra N. Mallick
language : en
Publisher: Cambridge University Press
Release Date : 2011-07-14

Rapid Eye Movement Sleep written by Birendra N. Mallick and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-07-14 with Medical categories.

Spanning over half a century of investigation into Rapid Eye Movement (REM) sleep, this volume provides comprehensive coverage of a broad range of topics in REM sleep biology. World renowned researchers and experts are brought together to discuss past and current research and to set the foundation for future developments. Key topics are covered in six sections from fundamental topics (historical context and general biology) to cutting-edge research on neuronal regulation, neuroanatomy and neurochemistry, functional significance and disturbance in the REM sleep generating mechanism. A reference source for all aspects of REM sleep research, it also incorporates chapters on neural modelling, findings from non-human species and interactions between brain regions. This is an invaluable resource, essential reading for all involved in sleep research and clinical practice.

Essential Leadership

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Author : Daniel Augusto Motta
language : en
Publisher: BMI Editora e Publicações LTDA
Release Date : 2017-11-10

Essential Leadership written by Daniel Augusto Motta and has been published by BMI Editora e Publicações LTDA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-11-10 with Business & Economics categories.

To the writer, Essential Leadership in based on three pillars —Personal Excellence, Individual Essence and Organization Transformation. Within this framework, a leader must understand, define, and impact an organization's strategy, seeing to its development and survival. Organizational objectives must be clear and aligned, and this is the mission of every leader, whatever the structure's size and complexity. To this end, leaders need to be aware of their three vectors —Adherence to Beliefs and Values, Consistent Productivity and Emotional Bond. ELOS Essential Leadership Skills for Organizational Strategy methodology is based on six elos, and each one has four drivers. The elos that need to be fully understood and cultivated are Competitive Environment, Value Proposition, Organization Essence, Strategic Execution, Essential Leadership and Performance Catalysts. This book also contains a rich, in-depth analysis of Europe's, China's and India's past, and points out to leaders the direction and the steps needed to redefine and achieve organizational goals. Forewords by two top executives and testimonials from six others are a testament to Motta's theory.

Immediate Early Genes And Inducible Transcription Factors In Mapping Of The Central Nervous System Function And Dysfunction

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Author : L. Kaczmarek
language : en
Publisher: Gulf Professional Publishing
Release Date : 2002-07-01

Immediate Early Genes And Inducible Transcription Factors In Mapping Of The Central Nervous System Function And Dysfunction written by L. Kaczmarek and has been published by Gulf Professional Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-07-01 with Medical categories.

That molecular neurobiology has become a dominant part of neuroscience research can be credited to the discovery of inducible gene expression in the brain and spinal cord. This volume deals with genes, whose expression patterns in the vertebrate central nervous system were the first to be revealed and then the most extensively investigated over the last 15 years. Immediate early genes (IEG) and their protein products, especially those acting as regulators of transcription (inducible transcription factors, ITF) have proven to be very valuable tools in functional neuroanatomy and neurophysiology, as they are rapidly and transiently induced in specific neurons in response to various modes of stimulation. Thus, they have been used to map neuronal populations selectively responsive to a variety of conditions, such as sensory and learning experience, electrical stimulation of specific circuits, seizures, and neurodegeneration.This single volume, written by the most prominent authors in the field, brings together for the first time information about the most widely studied IEG/ITF in a whole variety of phenomena of neuronal activation. It starts with a critical appraisal of the technologies employed for the studies on gene, protein, and transcription factor activity in the nervous system. Several chapters present exhaustive examples of expression patterns of the ITF in "vocal" avian brain, mammalian brain sensory regions, areas involved in regulation of circadian rhythms, and the spinal cord. The next parts cover functional and regular aspects of individual IEG/ITF expression: c-fos in learning and memory, c-jun and others in neuropathology and neuronal stress responses, Elk-1, egr family, and CREB in neuronal plasticity and learning. This volume will be useful as a major reference on this topic. Furthermore, it attempts to unravel the seemingly overwhelming complexity of the phenomena of gene expression in the central nervous system.