Immune Deficiency And Cancer
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Immune Deficiency And Cancer
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Author : Jean-Albert Gastaut
language : en
Publisher: Ellipses Marketing
Release Date : 2007
Immune Deficiency And Cancer written by Jean-Albert Gastaut and has been published by Ellipses Marketing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with categories.
According to the growing frequency of immunodeficiency-related cancers the authors wanted to report the current knowledge concerning these malignancies. They focus on cancers related to HIV infection or to immunosuppressive treatments given to transplant patients. Cancers hold a special position among numerous severe manifestations occurring during HIV infection. With the correction of immunosuppression due to highly active antiretroviral therapies (HAART) opportunistic infections became rare in HIV-infected patients. Conversely AIDS-defining and non-AIDS-defining cancers remain present but benefit from therapeutical advances. Solid-organ transplantations and allogeneic hematopoietic stem cells transplantations are more and more frequent and efficient. However long term immunosuppressive treatments - to prevent organ rejection - increase the risk of transplant-related cancers. These latter can be treated with standard oncologic therapies. Some of them are able to regress with the reduction or withdrawal of the immunosuppressive treatment.
The Relationship Between Cancer Predisposition And Primary Immunodeficiency
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Author : Fabian Hauck
language : en
Publisher: Frontiers Media SA
Release Date : 2019-11-21
The Relationship Between Cancer Predisposition And Primary Immunodeficiency written by Fabian Hauck and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-21 with categories.
Immune Deficiency And Cancer
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Author : David T Purtilo
language : en
Publisher:
Release Date : 1984-06-01
Immune Deficiency And Cancer written by David T Purtilo and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1984-06-01 with categories.
Immune Deficiency And Cancer
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Author : David T. Purtilo
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Immune Deficiency And Cancer written by David T. Purtilo and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
The discoveries of Burkitt, Epstein, and Henle have laid the foundation for continuing generation of information regarding the mechanisms of induction of diseases by Epstein-Barr virus. The discovery of the virus two decades ago resulted from clinical and basic science collaborative studies on Burkitt lymphoma. Subse quently, nasopharyngeal carcinoma and infectious mononucleosis have been linked etiologically with the virus. During the first decade of research following the discovery of the virus, the mechanisms for the induction of BL, NPC, and IM were sought. At that time one prevailing view was that individual oncogenic strains of EBV were responsible for the different disorders. Paralleling the development of immunology in the 1970's was the accrual of knowledge about immunological events occurring during IM. These studies suggest that immune defense mechanisms deter mine the outcome of this viral infection rather than different viral strains. During the early 1970's, Starzl and Penn and Gatti and Good had noted an increased frequency of malignancy in renal allograft recipients and children with primary immune deficiency disorders, respectively. These observations provoked investigators to restudy the role of immune surveillance against malignancy. At that time immune surveillance was thought to occur against tumor-specific antigens; thereby neoplasms were eliminated.
Fast Facts Immuno Oncology
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Author : Stephen Clarke
language : en
Publisher: Karger Medical and Scientific Publishers
Release Date : 2021-07-07
Fast Facts Immuno Oncology written by Stephen Clarke and has been published by Karger Medical and Scientific Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-07-07 with Medical categories.
The treatment of cancer has been revolutionized by therapies that modulate the immune system, with benefits for quality of life and survival. Standards of care have changed to reflect developments, but the area is moving fast. Keeping abreast of new therapies and trial data can be challenging. This second edition of 'Fast Facts: Immuno-Oncology' takes you from the fundamentals of immunology through to the new concepts of immunoediting and immunotherapy and likely future directions. Whether you have worked in oncology for decades and need a refresher or you are just starting out and need a crash course, this book provides all you need to know about immuno-oncology, concisely summarized. Table of Contents: • Components of the immune system • How cancers evade the immune system • How cancer immunotherapy works • Clinical use of immune checkpoint inhibitors • The future of immuno-oncology
The End Of The Beginning
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Author : Michael Kinch
language : en
Publisher: Simon and Schuster
Release Date : 2019-04-02
The End Of The Beginning written by Michael Kinch and has been published by Simon and Schuster this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-04-02 with Medical categories.
For the first time since a 5th century Greek physician gave the name “cancer” (karkinos, in Greek) to a deadly disease first described in Egyptian Papyri, the medical world is near a breakthrough that could allow even the most conservative doctors and pragmatic patients to use the other “c word” – cure – in the same sentence as cancer. A remarkable series of events has brought us to this point, thanks in large part to a new ability to more efficiently harness the extraordinary power of the human immune system.The End of the Beginning is a remarkable history of cancer treatment and the evolution of our understanding of its dynamic interplay with the immune system. Through Michael Kinch’s personal experience as a cancer researcher and the head of the oncology program at a leading biotechnology company, we witness the incredible accumulation of breakthrough science and its rapid translation into life-saving technologies that have begun to dramatically increase the quality and quantity of life for cancer patients. In clear and accessible prose, Kinch details the remarkable history of people, science, technology and disease and presents thrilling next-generation technologies that hold the promise to eliminate cancer for some, and perhaps ultimately, for all.
Immunosuppression And Human Malignancy
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Author : David Naor
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Immunosuppression And Human Malignancy written by David Naor and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
The immune system can deal effectively with the majority of viruses and bacteria, less effectively with parasites, and very poorly with cancer. Why is this so? Why are McFarlane Burnet's and Lewis Thomas' predictions that the immune system is in volved in ridding the body of cancer cells, encapsulated in the catchy phrase "immunologic surveillance," so difficult to experi mentally establish? Cancer differs from infectious agents in being derived from the host. Hence, it has been postulated that cancer cells lack anti gens that the immune system can recognize. They are not "im munogenic. " However, this argument is seriously weakened by the existence of numerous human autoimmune diseases, in which the immune system effectively recognizes and attacks a va riety of self tissues. Thus, the potential clearly exists for recogni tion of the surfaces of tumor cells. Professor Naor and his colleagues have written a book that explores another possible reason: cancer cells are recognized by the immune system-but is it possible that the consequence of recognition is inhibition of the immune system-by suppressor T cells or macrophages? The evolution of the malignant state may only occur in individuals who develop this suppression. This book reviews the evidence that suppressor cells, poorly characterized and difficult to study, may be of fundamental im portance in cancer. In fact, our incapacity to understand the na ture of suppressor cells and their mode of action is one of the ma jor problems in immunology research today.
Interaction Of Immune And Cancer Cells
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Author : Magdalena Klink
language : en
Publisher: Springer Nature
Release Date : 2022-02-14
Interaction Of Immune And Cancer Cells written by Magdalena Klink and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-02-14 with Medical categories.
Now, it its second edition, this book summarizes the role of immune cells in tumor suppression and progression. It describes in detail why tumor cells can survive and spread in spite of the antitumor response of immune cells. Since immunotherapy is an attractive approach to cancer therapy, this book also provides information on the two main strategies: monoclonal antibodies and adaptive T cell immunotherapy, with a focus on recent human clinical trials. A newly added chapter also focuses on the role of Natural Killer cells in tumor progression. The book provides a state-of-the-art, comprehensive overview of immune cells in cancer and is an indispensable resource for researchers and practitioners working or lecturing in the field of cancer research and immunology.
Immune Deficient Animals
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Author : Bernard Sordat
language : en
Publisher: S. Karger AG (Switzerland)
Release Date : 1984
Immune Deficient Animals written by Bernard Sordat and has been published by S. Karger AG (Switzerland) this book supported file pdf, txt, epub, kindle and other format this book has been release on 1984 with Medical categories.
Mechanisms Of Action And Therapeutic Applications Of Biologicals In Cancer And Immune Deficiency Disorders
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Author : David W. Golde
language : en
Publisher: Alan R. Liss
Release Date : 1989
Mechanisms Of Action And Therapeutic Applications Of Biologicals In Cancer And Immune Deficiency Disorders written by David W. Golde and has been published by Alan R. Liss this book supported file pdf, txt, epub, kindle and other format this book has been release on 1989 with Medical categories.