Immunoinformatics


Immunoinformatics
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Immunoinformatics


Immunoinformatics
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Author : Christian Schönbach
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-11-21

Immunoinformatics written by Christian Schönbach and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-11-21 with Medical categories.


In contrast to existing books on immunoinformatics, this volume presents a cross-section of immunoinformatics research. The contributions highlight the interdisciplinary nature of the field and how collaborative efforts among bioinformaticians and bench scientists result in innovative strategies for understanding the immune system. Immunoinformatics is ideal for scientists and students in immunology, bioinformatics, microbiology, and many other disciplines.



Immunoinformatics


Immunoinformatics
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Author : Darren R. Flower
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-02-07

Immunoinformatics written by Darren R. Flower and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-02-07 with Science categories.


This volume both engages the reader and provides a sound foundation for the use of immunoinformatics techniques in immunology and vaccinology. It addresses databases, HLA supertypes, MCH binding, and other properties of immune systems. The book contains chapters written by leaders in the field and provides a firm background for anyone working in immunoinformatics in one easy-to-use, insightful volume.



Immunoinformatics


Immunoinformatics
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Author : Gregory R. Bock
language : en
Publisher: John Wiley & Sons
Release Date : 2004-03-05

Immunoinformatics written by Gregory R. Bock and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-03-05 with Medical categories.


The astounding diversity of the immune system and the complexity of its regulatory pathways makes immunology a combinatorial science. Computational analysis has therefore become an essential element of immunology research and this has led to the creation of the emerging field of immunoinformatics. This book is the first to feature thorough coverage of this new field. Immunoinformatics facilitates the understanding of immune function by modelling the interactions among immunological components. Biological research provides ever deeper insights into the complexity of living organisms while computer science provides an effective means to store and analyse large volumes of complex data. Combining the two fields increases the efficiency of biological research and offers the potential for major advances in the study of biological systems. This book encompasses key developments in immunoinformatics, including immunological databases, sequence analysis, structure modelling, mathematical modelling of the immune system, simulation of laboratory experiments, statistical support for immunological experimentation and immunogenomics. The difficulties in effective application of bioinformatic tools in immunology arise at both ends of the spectrum: most immunologists have only a limited comprehension of sophisticated data analysis and applicability and limitations, while the average computer scientist lacks knowledge of the depth and complexity of biological data. The purpose of this book, therefore, is to present contributions from a multidisciplinary team of biologists and computer scientists to explore the issues related to better understanding of immune function and, in particular, to help apply new computer science methods to immunological research. Related Novartis Foundation symposia: 247 In Silico Simulation of Biological Processes Chair: Denis Noble 252 Generation and effector functions of regulatory lymphocytes Chair: Jean-François Bach



Immunoinformatics Of Cancers


Immunoinformatics Of Cancers
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Author : Nima Rezaei
language : en
Publisher: Academic Press
Release Date : 2022-04-19

Immunoinformatics Of Cancers written by Nima Rezaei and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-04-19 with Medical categories.


Immunoinformatics of Cancers: Practical Machine Learning Approaches Using R takes a bioinformatics approach to understanding and researching the immunological aspects of malignancies. It details biological and computational principles and the current applications of bioinformatic approaches in the study of human malignancies. Three sections cover the role of immunology in cancers and bioinformatics, including databases and tools, R programming and useful packages, and present the foundations of machine learning. The book then gives practical examples to illuminate the application of immunoinformatics to cancer, along with practical details on how computational and biological approaches can best be integrated.This book provides readers with practical computational knowledge and techniques, including programming, and machine learning, enabling them to understand and pursue the immunological aspects of malignancies. Presents the knowledge researchers need to apply computational techniques to immunodeficiencies Provides the most practical material for bioinformatics approaches to the immunology of cancers Gives straightforward and efficient explanations of programming and machine learning approaches in R Includes details of the most useful databases, tools, programming packages and algorithms for immunoinformatics Illuminates clear explanations with practical examples of immunoinformatic approaches to cancer



Bioinformatics For Immunomics


Bioinformatics For Immunomics
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Author : Darren D.R. Flower
language : en
Publisher: Springer
Release Date : 2009-10-03

Bioinformatics For Immunomics written by Darren D.R. Flower and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-10-03 with Medical categories.


Like many words, the term “immunomics” equates to different ideas contingent on context. For a brief span, immunomics meant the study of the Immunome, of which there were, in turn, several different definitions. A now largely defunct meaning rendered the Immunome as the set of antigenic peptides or immunogenic proteins within a single microorganism – be that virus, bacteria, fungus, or parasite – or microbial population, or antigenic or allergenic proteins and peptides derived from the environment as a whole, containing also proteins from eukaryotic sources. However, times have changed and the meaning of immunomics has also changed. Other newer definitions of the Immunome have come to focus on the plethora of immunological receptors and accessory molecules that comprise the host immune arsenal. Today, Immunomics or immunogenomics is now most often used as a synonym for high-throughput genome-based immunology. This is the study of aspects of the immune system using high-throughput techniques within a conc- tual landscape borne of both clinical and biophysical thinking.



Immunoinformatics


Immunoinformatics
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Author : Namrata Tomar
language : en
Publisher: Humana
Release Date : 2021-03-26

Immunoinformatics written by Namrata Tomar and has been published by Humana this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-03-26 with Medical categories.


This book covers a wide range of diverse immunoinformatics research topics, involving tools and databases of potential epitope prediction, HLA gene analysis, MHC characterizing, in silico vaccine design, mathematical modeling of host-pathogen interactions, and network analysis of immune system data. In that way, this fully updated volume explores the enormous value of computational tools and models in immunology research. Written for the highly successful Methods in Molecular Biology series, chapters include the kind of key insights and detailed implementation advice to encourage successful results in the lab. Authoritative and practical, Immunoinformatics, Third Edition serves as an ideal guide for scientists working at the intersection of bioinformatics, mathematical modelling, and statistics for the study of immune systems biology.



In Silico Immunology


In Silico Immunology
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Author : Darren D.R. Flower
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-04-16

In Silico Immunology written by Darren D.R. Flower and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-04-16 with Medical categories.


This book outlines three emergent disciplines, which are now poised to engineer a paradigm shift from hypothesis- to data-driven research: theoretical immunology, immunoinformatics, and Artificial Immune Systems. It details how these disciplines will enable new understanding to emerge from the analysis of complex datasets. Coverage shows how these three are set to transform immunological science and the future of health care.



Immunoinformatics


Immunoinformatics
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Author : Darren R. Flower
language : en
Publisher: Humana Press
Release Date : 2007-06-21

Immunoinformatics written by Darren R. Flower and has been published by Humana Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-06-21 with Science categories.


This volume both engages the reader and provides a sound foundation for the use of immunoinformatics techniques in immunology and vaccinology. It addresses databases, HLA supertypes, MCH binding, and other properties of immune systems. The book contains chapters written by leaders in the field and provides a firm background for anyone working in immunoinformatics in one easy-to-use, insightful volume.



Bioinformatics For Immunomics


Bioinformatics For Immunomics
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Author : Darren D.R. Flower
language : en
Publisher: Springer
Release Date : 2009-11-05

Bioinformatics For Immunomics written by Darren D.R. Flower and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-11-05 with Medical categories.


Like many words, the term “immunomics” equates to different ideas contingent on context. For a brief span, immunomics meant the study of the Immunome, of which there were, in turn, several different definitions. A now largely defunct meaning rendered the Immunome as the set of antigenic peptides or immunogenic proteins within a single microorganism – be that virus, bacteria, fungus, or parasite – or microbial population, or antigenic or allergenic proteins and peptides derived from the environment as a whole, containing also proteins from eukaryotic sources. However, times have changed and the meaning of immunomics has also changed. Other newer definitions of the Immunome have come to focus on the plethora of immunological receptors and accessory molecules that comprise the host immune arsenal. Today, Immunomics or immunogenomics is now most often used as a synonym for high-throughput genome-based immunology. This is the study of aspects of the immune system using high-throughput techniques within a conc- tual landscape borne of both clinical and biophysical thinking.



Immunogenetics


Immunogenetics
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Author : Anton W. Langerak
language : en
Publisher: Humana
Release Date : 2022-06-28

Immunogenetics written by Anton W. Langerak and has been published by Humana this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-06-28 with Medical categories.


This open access book explores techniques for working in the field of immunogenetics, i.e. fundamental and translational research into the adaptive immune receptor repertoire. Many chapters are dedicated to lab protocols, bioinformatics, and immunoinformatics analysis of high-resolution immunome analysis, exemplified by numerous applications. Additionally, the newest technological variations on these protocols are discussed, including non-amplicon, single-cell, and cell-free strategies. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Immunogenetics: Methods and Protocols covers a broad spectrum of methodologies for applications in research and clinical diagnostics to illustrate the impact that immunogenetics has achieved and will further expand in all fields of medicine, from infection and (auto)immunity, to vaccination, to lymphoid malignancy and tumor immunity.