Immunologic Signatures Of Rejection
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Immunologic Signatures Of Rejection
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Author : Francesco M. Marincola
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-11-03
Immunologic Signatures Of Rejection written by Francesco M. Marincola and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-11-03 with Medical categories.
This book discusses the mechanisms leading to immune-mediated tissue rejection following the hypothesis that independent of the disease process the final effector mechanism is shared by most (but not all) pathologies and it is relatively simple. The book covers evidence gathered to support the thesis by studies performed in humans during rejection or in experimental models and will focus particularly (but not exclusively) on the analysis of the rejected tissue rather than the systemic circulation. Several disease processes are discussed including example of chronic inflammatory process without resolution of the pathologic process and acute one with resolution of the pathologic process (clearance of pathogen, rejection of tumor) or unwanted tissue destruction (allograft rejection, autoimmunity).
Immunologic Signatures Of Rejection
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Author : Francesco M. Marincola
language : en
Publisher: Springer
Release Date : 2011-06-03
Immunologic Signatures Of Rejection written by Francesco M. Marincola and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-06-03 with Medical categories.
This book discusses the mechanisms leading to immune-mediated tissue rejection following the hypothesis that independent of the disease process the final effector mechanism is shared by most (but not all) pathologies and it is relatively simple. The book covers evidence gathered to support the thesis by studies performed in humans during rejection or in experimental models and will focus particularly (but not exclusively) on the analysis of the rejected tissue rather than the systemic circulation. Several disease processes are discussed including example of chronic inflammatory process without resolution of the pathologic process and acute one with resolution of the pathologic process (clearance of pathogen, rejection of tumor) or unwanted tissue destruction (allograft rejection, autoimmunity).
Cancer Immunotherapy Principles And Practice Second Edition
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Author : Lisa H. Butterfield
language : en
Publisher: Springer Publishing Company
Release Date : 2021-08-25
Cancer Immunotherapy Principles And Practice Second Edition written by Lisa H. Butterfield and has been published by Springer Publishing Company this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-08-25 with Medical categories.
Thoroughly updated to reflect major advances in the field of immuno-oncology, this second edition of Cancer Immunotherapy Principles and Practice, from the Society for Immunotherapy of Cancer (SITC), remains the definitive resource for information on tumor immunology and cancer immunotherapy treatments. An essential reference for both novice and experienced cancer researchers, oncologists, and related practitioners alike, the book not only guides readers through the fundamental scientific principles of the field all the way to translational and practical clinical applications for treating and managing oncologic disease, but also provides a comprehensive understanding of the regulatory processes that support the safe and effective delivery of immunotherapy to patients with cancer. The expanded and updated second edition now spans 68 chapters, including 12 new chapters, covering major topics and innovations that have shaped the rapid development of immunotherapy and its ascension into the standard of care as first-line treatment for a growing number of disease settings. New to this edition are chapters with deeper insight into our understanding of cancer genomics and determinants of response, immunogenic cell death, cancer and stromal cell-intrinsic pathways of immune resistance, cancer immune exclusion, adoptive cell therapy, metabolomics, tumor mutation burden, immunotherapy in combination with radiation therapy, synthetic biology, and more. Complete with detailed illustrations, tables, and key points for targeted reference, Cancer Immunotherapy Principles and Practice, Second Edition is the most comprehensive and authoritative resource for scientists and clinicians looking to expand their knowledge base of this dynamic field. Key Features: Offers key insights and perspectives on cancer immunology and immunotherapy treatments from renowned experts in the field Covers the basic principles and science behind cancer immunotherapy and tumor immunology Includes treatment strategies for a vast array of available immunotherapy classes and agents, such as cytokine therapies, oncolytic viruses, cancer vaccines, CAR T therapies, and combination immunotherapies Provides essential information on FDA-approved immunotherapies, including clinical management and outcome data related to response rates, risks, and toxicities Discusses special considerations for immunotherapy in the context of specific disease settings, including skin cancers, genitourinary cancers, gastrointestinal cancers, hepatocellular carcinomas, gynecologic malignancies, breast cancers, lung cancers, head and neck cancers, brain tumors, sarcomas, pediatric cancers, and treatments combined with radiation therapy Clarifies the complex regulatory aspects behind the development and approval of immunotherapy drugs
Cancer Immunotherapy Principles And Practice
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Author : Lisa H. Butterfield
language : en
Publisher: Springer Publishing Company
Release Date : 2017-06-28
Cancer Immunotherapy Principles And Practice written by Lisa H. Butterfield and has been published by Springer Publishing Company this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-06-28 with Medical categories.
“Drs. Butterfield, Kaufman and Marincola on behalf of the SITC have created a comprehensive must-have resource covering the basic and translational science behind approved and investigational immune therapies, and disease-by-disease clinical application of the therapies, written by leaders in the field. The textbook will be highly valuable reading for those just entering the field and for experienced scientists and clinicians looking to expand their knowledge base.”—Mario Sznol, MD, Professor of Medicine (Medical Oncology), Yale School of Medicine, New Haven, Connecticut “Given the important and exciting advances in cancer immunotherapy, it is not surprising that there is no dearth of books on the subject. Despite the competition, however, this book is a unique masterpiece and a must-have comprehensive resource for anyone interested in this area and for every medical library.” Score: 100, 5 Stars, Doody’s Medical Reviews Cancer Immunotherapy Principles and Practice, from the Society for Immunotherapy of Cancer (SITC), is the authoritative reference on cancer immunobiology and the immunotherapy treatments that harness the immune system to combat malignant disease. Featuring five sections and over 50 chapters covering the Basic Principles of Tumor Immunology, Cancer Immunotherapy Targets and Classes, Immune Function in Cancer Patients, Disease-Specific Treatments and Outcomes, and Regulatory Aspects of Cancer Immunotherapy, this book covers all major topics that have shaped the development of immunotherapy and propelled it to its current place at the forefront of cancer treatment innovation. This volume is a comprehensive resource for oncologists and fellows, immunologists, cancer researchers, and related practitioners seeking understanding of the basic science and clinical applications of cancer immunotherapy. As well as presenting the evidence for immune-based cancer treatment, it positions immunotherapy in the context of other available cancer treatments and provides data on response rates, risks, and toxicities across a variety of diseases. Filled with detailed tables, and instructive illustrations, as well as key points for quick reference, Cancer Immunotherapy Principles and Practice simplifies a challenging and dynamic subject. KEY FEATURES Clearly summarizes the basic principles and research supporting cancer immunotherapy clinical translation Contains expert guidance and treatment strategies for all immunotherapy classes and agents, including cell-based therapies, monoclonal antibodies, cytokine therapies, checkpoint inhibitors, oncolytic viruses, adjuvant approaches, and treatment combinations Includes expert perspectives from leading authorities in the field Provides information on all FDA-approved immunotherapies, including clinical management and outcome data Discusses clinical aspects of immunotherapy for individual cancer types, including melanoma and other skin cancers, lung cancers, gynecologic cancers, gastrointestinal cancers, hematologic cancers, genitourinary cancers, head and neck cancers, sarcomas, brain and other CNS cancers, breast cancer, and pediatric malignancies. Explains regulatory aspects behind the development and approval of immunotherapy drugs
Mechanisms Of Lymphocyte Exclusion In The Tumor Microenvironment
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Author : Sarah E. Church
language : en
Publisher: Frontiers Media SA
Release Date : 2022-05-24
Mechanisms Of Lymphocyte Exclusion In The Tumor Microenvironment written by Sarah E. Church and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-05-24 with Medical categories.
Cancer Immunology
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Author : Nima Rezaei
language : en
Publisher: Springer Nature
Release Date : 2020-01-03
Cancer Immunology written by Nima Rezaei and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-01-03 with Medical categories.
This book focusing on the immunopathology of cancers is published as part of the three-volume Springer series Cancer Immunology, which aims to provide an up-to-date, clinically relevant review of cancer immunology and immunotherapy. Readers will find detailed descriptions of the interactions between cancerous cells and various components of the innate and adaptive immune system. The principal focus, however, is very much on clinical aspects, the aim being to educate clinicians in the clinical implications of the latest research and novel developments in the field. In the new edition of this very well received book, first published in 2015, the original chapters have been significantly updated and additional chapters included on, for example, current knowledge on the roles of T-helper cells and NK cells in tumor immunity, the part played by oncoviruses in the development of various cancers, and the applications of fluorescent in situ hybridization, bioluminescence, and cancer molecular and functional imaging. Cancer Immunology: A Translational Medicine Context will be of special value to clinical immunologists, hematologists, and oncologists.
Manual Of Molecular And Clinical Laboratory Immunology
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Author : Barbara Detrick
language : en
Publisher: John Wiley & Sons
Release Date : 2020-07-16
Manual Of Molecular And Clinical Laboratory Immunology written by Barbara Detrick and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-07-16 with Medical categories.
THE authoritative guide for clinical laboratory immunology For over 40 years the Manual of Molecular and Clinical Laboratory Immunology has served as the premier guide for the clinical immunology laboratory. From basic serology testing to the present wide range of molecular analyses, the Manual has reflected the exponential growth in the field of immunology over the past decades. This eighth edition reflects the latest advances and developments in the diagnosis and treatment of patients with infectious and immune-mediated disorders. The Manual features detailed descriptions of general and specific methodologies, placing special focus on the interpretation of laboratory findings, and covers the immunology of infectious diseases, including specific pathogens, as well as the full range of autoimmune and immunodeficiency diseases, cancer, and transplantation. Written to guide the laboratory director, the Manual will also appeal to other laboratory scientists, especially those working in clinical immunology laboratories, and pathologists. It is also a useful reference for physicians, mid-level providers, medical students, and allied health students with an interest in the role that immunology plays in the clinical laboratory.
Immunology Serology In Laboratory Medicine E Book
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Author : Mary Louise Turgeon
language : en
Publisher: Elsevier Health Sciences
Release Date : 2020-12-16
Immunology Serology In Laboratory Medicine E Book written by Mary Louise Turgeon and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-12-16 with Medical categories.
Building on a solid foundation of knowledge and skills, this classic text from trusted author Mary Louise Turgeon clearly explains everything from basic immunologic mechanisms and serologic concepts to the theory behind procedures performed in the lab. This go-to resource prepares you for everything from mastering automated techniques to understanding immunoassay instrumentation and disorders of infectious and immunologic origin. Packed with learning objectives, review questions, step-by-step procedures, and case studies, this text is the key to your success in today's modern laboratory environment. - Procedural protocols help you transition from immunology theory to practical aspects of the clinical lab. - Case studies allow you to apply your knowledge to real-world situations and strengthen your critical thinking skills. - Updated illustrations, photographs, and summary tables visually clarify key concepts and information. - Full-color presentation clearly showcases diagrams and micrographs, giving you a sense of what you will encounter in the lab. - Learning objectives and key terms at the beginning of each chapter provide measurable outcomes and a framework for organizing your study efforts. - Review questions at the end of each chapter provide you with review and self-assessment opportunities. - NEW! Highlights of Immunology chapter presents a clear, accessible, and easy-to-understand introduction to immunology that will help you grasp the complex concepts you need to understand to practice in the clinical lab. - NEW! Stronger focus on molecular laboratory techniques. - NEW! Ten chapters include COVID-19 related topics, including Primer on Vaccines chapter covering newer vaccine production methods focusing on DNA and RNA nucleic acids and viral vectors, and covering eight different platforms in use for vaccine research and development against SARS-CoV-2 virus. - NEW! All chapters include significant updates based on reviewer feedback. - NEW! Key Concepts interwoven throughout each chapter highlight important facts for more focused learning.
Tumor Immune Microenvironment Topographies For Prediction And Evaluation Unlock The Mystery Of The Therapeutic Effects And Adverse Events Of Tumor Immunotherapy
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Author : Xiaoran Yin
language : en
Publisher: Frontiers Media SA
Release Date : 2023-11-24
Tumor Immune Microenvironment Topographies For Prediction And Evaluation Unlock The Mystery Of The Therapeutic Effects And Adverse Events Of Tumor Immunotherapy written by Xiaoran Yin and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-11-24 with Medical categories.
Immunotherapy As An Evolving Approach For The Treatment Of Breast Cancer
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Author : Mai F. Tolba
language : en
Publisher: Frontiers Media SA
Release Date : 2022-01-13
Immunotherapy As An Evolving Approach For The Treatment Of Breast Cancer written by Mai F. Tolba and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-13 with Medical categories.