Immunology And Evolution Of Infectious Disease
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Immunology And Evolution Of Infectious Disease
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Author : Steven A. Frank
language : en
Publisher: Princeton University Press
Release Date : 2020-10-06
Immunology And Evolution Of Infectious Disease written by Steven A. Frank and has been published by Princeton University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-10-06 with Medical categories.
From HIV to influenza, the battle between infectious agents and the immune system is at the heart of disease. Knowledge of how and why parasites vary to escape recognition by the immune system is central to vaccine design, the control of epidemics, and our fundamental understanding of parasite ecology and evolution. As the first comprehensive synthesis of parasite variation at the molecular, population, and evolutionary levels, this book is essential reading for students and researchers throughout biology and biomedicine. The author uses an evolutionary perspective to meld the terms and findings of molecular biology, immunology, pathogen biology, and population dynamics. This multidisciplinary approach offers newcomers a readable introduction while giving specialists an invaluable guide to allied subjects. Every aspect of the immune response is presented in the functional context of parasite recognition and defense--an emphasis that gives structure to a tremendous amount of data and brings into sharp focus the great complexity of immunology. The problems that end each chapter set the challenge for future research, and the text includes extensive discussion of HIV, influenza, foot-and-mouth disease, and many other pathogens. This is the only book that treats in an integrated way all factors affecting variation in infectious disease. It is a superb teaching tool and a rich source of ideas for new and experienced researchers. For molecular biologists, immunologists, and evolutionary biologists, this book provides new insight into infectious agents, immunity, and the evolution of infectious disease.
Infectious Disease And Host Pathogen Evolution
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Author : Krishna R. Dronamraju
language : en
Publisher: Cambridge University Press
Release Date : 2004-04-05
Infectious Disease And Host Pathogen Evolution written by Krishna R. Dronamraju and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-04-05 with Science categories.
This book, originally published in 2004, is concerned with the links between human evolution and infectious disease. It has long been recognised that an important factor in human evolution has been the struggle against infectious disease and, more recently, it was revealed that complex genetic polymorphisms are the direct result of that struggle.
Genetics And Evolution Of Infectious Diseases
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Author : Michel Tibayrenc
language : en
Publisher: Elsevier
Release Date : 2010-12-17
Genetics And Evolution Of Infectious Diseases written by Michel Tibayrenc and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-12-17 with Medical categories.
Genetics and Evolution of Infectious Diseases is at the crossroads between two major scientific fields of the 21st century: evolutionary biology and infectious diseases. The genomic revolution has upset modern biology and has revolutionized our approach to ancient disciplines such as evolutionary studies. In particular, this revolution is profoundly changing our view on genetically driven human phenotypic diversity, and this is especially true in disease genetic susceptibility. Infectious diseases are indisputably the major challenge of medicine. When looking globally, they are the number one killer of humans and therefore the main selective pressure exerted on our species. Even in industrial countries, infectious diseases are now far less under control than 20 years ago. The first part of this book covers the main features and applications of modern technologies in the study of infectious diseases. The second part provides detailed information on a number of the key infectious diseases such as malaria, SARS, avian flu, HIV, tuberculosis, nosocomial infections and a few other pathogens that will be taken as examples to illustrate the power of modern technologies and the value of evolutionary approaches. Takes an integrated approach to infectious diseases Includes contributions from leading authorities Provides the latest developments in the field
Pertussis
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Author : Pejman Rohani
language : en
Publisher: Oxford University Press
Release Date : 2018-12-06
Pertussis written by Pejman Rohani and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-12-06 with Medical categories.
Pertussis, or whooping cough, is a respiratory disease caused primarily by infection with the bacterium Bordetella pertussis. It remains among the leading causes of death amongst vaccine-preventable diseases worldwide and recent years have seen its alarming re-emergence in many regions (including the U.S. and much of Europe), despite sustained high levels of vaccine coverage. The causes of the resurgence remain contentious, in part due to inherent complexities of the pathogen's biology, in part due to pronounced variation in the treatment and prevention strategies between different countries and regions, and in part due to long-standing disagreement amongst scientific researchers studying pertussis. This edited volume brings together expert knowledge from disparate fields with the overall aim of synthesizing the current understanding of this critically important, global pathogen.
Evolutionary Concepts In Immunology
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Author : Robert Jack
language : en
Publisher: Springer
Release Date : 2019-06-13
Evolutionary Concepts In Immunology written by Robert Jack and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-06-13 with Medical categories.
Immunology is a nodal subject that links many areas of biology. It permeates the biosciences, and also plays crucial roles in diagnosis and therapy in areas of clinical medicine ranging from the control of infectious and autoimmune diseases to tumour therapy. Monoclonal antibodies and small molecule modulators of immunity are major factors in the pharmaceutical industry and now constitute a multi billion dollar business. Students in these diverse areas are frequently daunted by the complexity of immunology and the astonishing array of unusual mechanisms that go to make it up. Starting from Dobzhansky’s famous slogan, “Nothing in biology makes sense except in the light of evolution”, this book will serve to illuminate how evolutionary forces shaped immunity and thus provide an explanation for how many of its counter intuitive oddities arose. By doing so it will provide a conceptual framework on which students may organise the rapidly growing flood of immunological knowledge.
Fundamental Immunology
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Author : William E. Paul
language : en
Publisher: Lippincott Williams & Wilkins
Release Date : 2012-12-10
Fundamental Immunology written by William E. Paul and has been published by Lippincott Williams & Wilkins this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-10 with Medical categories.
Fundamental Immunology Seventh Edition This standard-setting textbook has defined the field of immunology since 1984, and is now in its Seventh Edition continuing to deliver the detailed, authoritative, and timely coverage readers expect. This comprehensive, up-to-date text is ideal for graduate students, post-doctoral fellows, basic and clinical immunologists, microbiologists and infectious disease physicians, and any physician treating diseases in which immunologic mechanisms play a role. Now full-color throughout the book's fully revised and updated content reflects the latest advances in the field. Current insights enhance readers' understanding of immune system function. The text's unique approach bridges the gap between basic immunology and the disease process. Extensive coverage of molecular biology explains the molecular dynamics underlying immune disorders and their treatment. Abundant illustrations and tables deliver essential information at a glance. Plus a convenient companion website features the fully searchable text with all references linked to PubMed. Look inside and discover... * Fully revised and updated content reflects the latest advances in the field. * Current insights enhance readers' understanding of immune system function * Unique approach bridges the gap between basic immunology and the disease process. * Extensive coverage of molecular biology explains the molecular dynamics underlying immune disorders and their treatment. * Abundant illustrations and tables deliver essential information at a glance. PLUS... A convenient companion website features the fully searchable text with all references linked to PubMed. Pick up your copy today!
Infections Disease And Host Pathogen Evolution
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Author : Krishna R. Dronamraju
language : en
Publisher:
Release Date : 2004
Infections Disease And Host Pathogen Evolution written by Krishna R. Dronamraju and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with Evolutionary genetics categories.
It has long been recognised that an important factor in human evolution has been the struggle against infectious disease and, more recently, it has been revealed that complex genetic polymorphisms are the direct result of that struggle. As molecular biological techniques become more sophisticated, a number of breakthroughs in the area of host-pathogen evolution have led to an increased interest in this field. From the historical beginnings of J.B.S. Haldane's original hypothesis to current research, this book strives to evaluate infectious diseases from an evolutionary perspective. It provides a survey of the latest information regarding host-pathogen evolution related to major infectious diseases and parasitic infections, including malaria, influenza and leishmaniasis. Written by leading authorities in the field, and edited by a former pupil of Haldane, Infectious Disease and Host-Pathogen Evolution will be a valuable reference for those working in related areas of microbiology, parasitology, immunology and infectious disease medicine, as well as genetics, evolutionary biology and epidemiology.
Infectious Disease Epidemiology
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Author : Ibrahim Abubakar
language : en
Publisher: Oxford University Press
Release Date : 2016-04-07
Infectious Disease Epidemiology written by Ibrahim Abubakar and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-04-07 with Medical categories.
Infectious Disease Epidemiology is a concise reference guide which provides trainees and practicing epidemiologists with the information that they need to understand the basic concepts necessary for working in this specialist area. Divided into two sections, part one comprehensively covers the basic principles and methods relevant to the study of infectious disease epidemiology. It is organised in order of increasing complexity, ranging from a general introduction to subjects such as mathematical modelling and sero-epidemiology. Part two examines key major infectious diseases that are of global significance. Grouped by their route of transmission for ease of reference, they include diseases that present a particular burden or a high potential for causing mortality. This practical guide will be essential reading for postgraduate students in infectious disease epidemiology, health protection trainees, and practicing epidemiologists.
Infectious Disease A Very Short Introduction
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Author : Marta Wayne
language : en
Publisher: OUP Oxford
Release Date : 2015-06-25
Infectious Disease A Very Short Introduction written by Marta Wayne and has been published by OUP Oxford this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-06-25 with Medical categories.
As doctors and biologists have learned, to their dismay, infectious disease is a moving target: new diseases emerge every year, old diseases evolve into new forms, and ecological and socioeconomic upheavals change the transmission pathways by which disease spread. By taking an approach focused on the general evolutionary and ecological dynamics of disease, this Very Short Introduction provides a general conceptual framework for thinking about disease. Ecology and evolution provide the keys to answering the 'where', 'why', 'how', and 'what' questions about any particular infectious disease: where did it come from? How is it transmitted from one person to another, and why are some individuals more susceptible than others? What biochemical, ecological, and evolutionary strategies can be used to combat the disease? Is it more effective to block transmission at the population level, or to block infection at the individual level? Through a series of case studies, Benjamin Bolker and Marta L. Wayne introduce the major ideas of infectious disease in a clear and thoughtful way, emphasising the general principles of infection, the management of outbreaks, and the evolutionary and ecological approaches that are now central to much research about infectious disease. ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.
Evolution Of Infectious Disease
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Author : Paul W. Ewald
language : en
Publisher: Oxford University Press
Release Date : 1994-01-06
Evolution Of Infectious Disease written by Paul W. Ewald and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994-01-06 with Science categories.
Findings from the field of evolutionary biology are yielding dramatic insights for health scientists, especially those involved in the fight against infectious diseases. This book is the first in-depth presentation of these insights. In detailing why the pathogens that cause malaria, smallpox, tuberculosis, and AIDS have their special kinds of deadliness, the book shows how efforts to control virtually all diseases would benefit from a more thorough application of evolutionary principles. When viewed from a Darwinian perspective, a pathogen is not simply a disease-causing agent, it is a self-replicating organism driven by evolutionary pressures to pass on as many copies of itself as possible. In this context, so-called "cultural vectors"--those aspects of human behavior and the human environment that allow spread of disease from immobilized people--become more important than ever. Interventions to control diseases don't simply hinder their spread but can cause pathogens and the diseases they engender to evolve into more benign forms. In fact, the union of health science with evolutionary biology offers an entirely new dimension to policy making, as the possibility of determining the future course of many diseases becomes a reality. By presenting the first detailed explanation of an evolutionary perspective on infectious disease, the author has achieved a genuine milestone in the synthesis of health science, epidemiology, and evolutionary biology. Written in a clear, accessible style, it is intended for a wide readership among professionals in these fields and general readers interested in science and health.