Implementation Of High Density Snp Data For Genetic Evaluation And Qtl Discovery In Beef Cattle
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Implementation Of High Density Snp Data For Genetic Evaluation And Qtl Discovery In Beef Cattle
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Author : Megan M. Rolf
language : en
Publisher:
Release Date : 2009
Implementation Of High Density Snp Data For Genetic Evaluation And Qtl Discovery In Beef Cattle written by Megan M. Rolf and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009 with Beef cattle categories.
A genomic relationship matrix was built using 1,707 Angus AI sires with complete pedigree information and 698 Angus steers with only paternity information. The genomic matrix was used to estimate breeding values (EBVs) on both sires and steers and residuals were estimated on the steers. EBV and residuals were combined to produce adjusted phenotypes corrected for fixed effects (year and season of birth within feeding pen) for three feed efficiency related traits (average daily feed intake, AFI; residual feed intake, RFI; and average daily gain, ADG). These dependent variables were used for whole genome association analysis. A genome-wide significance of threshold equivalent to p [lesser than] 0.05 was determined via dependant variable permutation analysis to control experiment wide error rate. Final models for the three traits were assembled using EBVs of steers and explained 54.097%, 62.687% and 54.724% of the genetic variance in AFI, RFI and ADG, respectively. Utility of predicted feed intakes for genetic selection was also tested. Predicted feed intakes (pDMR) were estimated using the Cornell Value Discovery System (CVDS) and were adjusted for fixed effects and EBVs were estimated. Whole genome analysis was performed and concordant SNP associations for ADG, RFI and AFI were identified. Index selection may include pDMR to increase information on feed intake, however correlated responses in ADG are likely if not used within an index.
Molecular And Quantitative Animal Genetics
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Author : Hasan Khatib
language : en
Publisher: John Wiley & Sons
Release Date : 2015-03-02
Molecular And Quantitative Animal Genetics written by Hasan Khatib and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-03-02 with Science categories.
Animal genetics is a foundational discipline in the fields of animal science, animal breeding, and veterinary sciences. While genetics underpins the healthy development and breeding of all living organisms, this is especially true in domestic animals, specifically with respect to breeding for key traits. Molecular and Quantitative Animal Genetics is a new textbook that takes an innovative approach, looking at both quantitative and molecular breeding approaches. The bookprovides a comprehensive introduction to genetic principles and their applications in animal breeding. This text provides a useful overview for those new to the field of animal genetics and breeding, covering a diverse array of topics ranging from population and quantitative genetics to epigenetics and biotechnology. Molecular and Quantitative Animal Genetics will be an important and invaluable educational resource for undergraduate and graduate students and animal agriculture professionals. Divided into six sections pairing fundamental principles with useful applications, the book's comprehensive coverage will make it an ideal fit for students studying animal breeding and genetics at any level.
Achieving Sustainable Production Of Pig Meat Volume 2
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Author : Emeritus Professor Julian Wiseman
language : en
Publisher: Burleigh Dodds Science Publishing
Release Date : 2017-10-09
Achieving Sustainable Production Of Pig Meat Volume 2 written by Emeritus Professor Julian Wiseman and has been published by Burleigh Dodds Science Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-10-09 with Technology & Engineering categories.
Reviews latest research on pig genetics and its implications for improved breeding Detailed review of ways of meeting energy, protein, vitamin and mineral requirements of pigs Assesses the role of exogenous enzymes, growth promotors, prebiotics and probiotics in pig nutrition
Multi Layered Genome Wide Association Prediction In Animals
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Author : Ruidong Xiang
language : en
Publisher: Frontiers Media SA
Release Date : 2022-04-29
Multi Layered Genome Wide Association Prediction In Animals written by Ruidong Xiang and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-04-29 with Science categories.
Application Of Genomics In Livestock Populations Under Selection Or Conservation
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Author : Anupama Mukherjee
language : en
Publisher: Frontiers Media SA
Release Date : 2024-02-06
Application Of Genomics In Livestock Populations Under Selection Or Conservation written by Anupama Mukherjee and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-02-06 with Science categories.
Animal Science Reviews 2010
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Author : David Hemming
language : en
Publisher: CABI
Release Date : 2011
Animal Science Reviews 2010 written by David Hemming and has been published by CABI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011 with Technology & Engineering categories.
Animal Science Reviews 2010 provides scientists and students in animal science with timely analysis on key topics in current research. Originally published online in CAB Reviews, this volume makes available in printed form the reviews in animal science published during 2010.
Genetic Variability In Conservation And Selection Programs In The Post Genomics Era
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Author : Maria Saura
language : en
Publisher: Frontiers Media SA
Release Date : 2020-12-22
Genetic Variability In Conservation And Selection Programs In The Post Genomics Era written by Maria Saura and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-12-22 with Science categories.
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Animal Genomics
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Author :
language : en
Publisher:
Release Date : 2000
Animal Genomics written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000 with Animal genetics categories.
A Hybrid Method For The Implementation Of Genomic Selection Based On Fst Prioritized Single Nucleotide Polymorphisms
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Author : Sajjad Toghiani
language : en
Publisher:
Release Date : 2018
A Hybrid Method For The Implementation Of Genomic Selection Based On Fst Prioritized Single Nucleotide Polymorphisms written by Sajjad Toghiani and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018 with categories.
Availability of high-density (HD) marker panels provides an opportunity to improve the accuracy of genomic selection (GS). Unfortunately, using HD panels resulted in no significant increase in the accuracy of GS. This lack of improvement in accuracy is more likely due to the limitations of current GS methods rather than the uselessness of HD data. Increasing variants in association models caused a reduction in statistical power. Increase in the number of genotyped animals complicated the inversion of the genomic relationship matrix. Thus, reducing the number of variants and eliminating the inversion of genomic relationship matrix are required for the full benefit from HD marker data. We proposed fixation index (FST) to prioritize SNPs for GS. To validate the usefulness of FST, a trait with heritability of 0.4 under different SNP densities was simulated. Prioritized top 2.5% markers were able to tag most significant QTL and to increase functional genomic similarity. The latter could be used as a decision-making or selection tool. In spite of being able to prioritize markers in linkage disequilibrium with relevant QTL, the latter explained only a portion of the genetic variance. This is the case because small effects QTL are often not tagged with the prioritized SNPs. These small effect QTL could be tracked, however, by a polygenic component. Thus, a hybrid model was proposed that included the prioritized SNPs and a polygenic component in the association model. The proposed approach was evaluated based on simulated data of a trait with heritability of 0.1 and 0.4 and a real data of weaning weight in beef cattle. Using only genotyped animals, the hybrid model outperformed BayesB, BayesC and GBLUP when the prioritized 2.5% SNPs were used in the association model. The hybrid model was extended to accommodate non-genotyped animals. It outperformed ssGBLUP method using simulated data under both heritability scenarios. Although the results of the evaluation are likely to depend on the data generating process including the genetic complexity of the trait, the hybrid model seemed to be competitive compared to current methods. Furthermore, its computational costs in terms of CPU time and peak memory are limited.
High Throughput Phenotyping In The Genomic Improvement Of Livestock
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Author : Fabyano Fonseca Silva
language : en
Publisher: Frontiers Media SA
Release Date : 2021-08-03
High Throughput Phenotyping In The Genomic Improvement Of Livestock written by Fabyano Fonseca Silva and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-08-03 with Science categories.