Infectious Process And Sepsis
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Infectious Process And Sepsis
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Author : Vincenzo Neri
language : en
Publisher: BoD – Books on Demand
Release Date : 2020-07-15
Infectious Process And Sepsis written by Vincenzo Neri and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-07-15 with Medical categories.
Sepsis is a very complex clinical condition that can be considered the central point of the infectious process: the arrival point in the evolution of a localized septic outbreak that has caused a systemic inflammatory reaction. In the clinical setting two important questions regarding the transition from local inflammation, with beneficial effect, to systemic inflammatory disease, with deleterious results, remain unanswered. First, why does the transition from local to systemic disease only occur in some subjects? Second, how long does this transition take? This book attempts to answer these questions. Chapters cover such topics as surgical infections, microbiota therapy in sepsis, cytokines for host immune response, and the role of serum amyloid A in the acute phase of sepsis.
Infections And Sepsis Development
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Author : Vincenzo Neri
language : en
Publisher: BoD – Books on Demand
Release Date : 2021-10-27
Infections And Sepsis Development written by Vincenzo Neri and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-10-27 with Medical categories.
Infection is a common clinical condition that may cause local inflammation but, in some cases, can lead to systemic inflammation, with sepsis and organ dysfunction. Septic shock is a condition of inadequate tissue perfusion and cellular use of oxygen due to the cytotoxic action of bacterial toxins. There is no relationship between the pathological characteristics and the severity of the primary septic outbreak and the development of septic shock, and the time that elapses until the start of the shock is not predictable. Thus, knowledge of the pathophysiology of septic shock is fundamental for treatment. This book presents a comprehensive overview of infectious agents and their therapeutic control, pathological conditions with infective etiology such as diabetic foot osteomyelitis and infections in neurosurgery, and the pathophysiology, diagnosis, and management of sepsis.
Sepsis
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Author : Simon V. Baudouin
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-06-02
Sepsis written by Simon V. Baudouin and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-06-02 with Medical categories.
Discover new, effective strategies to prevent and treat sepsis. In this book, leading medical experts consider how the pathways implicated in early and late sepsis interact. Next, the book describes numerous pharmacological approaches that enable you to provide state-of-the-technology care for patients in both early and late sepsis. You’ll also get detailed discussions of how the various physiological systems function under sepsis.
Evolving Concepts In Sepsis And Septic Shock
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Author : Peter Q. Eichacker
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Evolving Concepts In Sepsis And Septic Shock written by Peter Q. Eichacker and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Much research over the past 30 to 40 years has shown that the inflammatory response, while critical for host defense during microbial infection, may itself play a central role in the pathogenesis of sepsis. Although key mediators responsible for this injury have been identified, efforts clinically to augment our conventional antimicrobial and supportive therapies during sepsis with agents modulating the inflammatory response have been unsuccessful. As a result, the mortality associated with this lethal syndrome, especially when complicated by shock, has remained persistently high. Unfortunately, during this same period of time, the incidence of sepsis has accelerated as other fields of medicine have relied increasingly on therapies that predispose to infection. While frustrating, overall this experience in the field of sepsis has not been without value. Most importantly, it has helped define on several different levels the complexity of the septic patient. Recognizing and addressing this complexity as discussed by each of the contributors to Evolving Concepts in Sepsis and Septic Shock may now provide new inroads into the treatment of sepsis.
Cytokines In Severe Sepsis And Septic Shock
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Author : H. Redl
language : en
Publisher: Springer
Release Date : 2013-03-11
Cytokines In Severe Sepsis And Septic Shock written by H. Redl and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-11 with Medical categories.
t Heinz Red! and Gunther Sch!ag Ludwig Boltzmann Institute for Experimental and Clinical Traumatology, Vienna, Austria The word "sepsis" derives from the Greek meaning decay or rottenness. Tradition ally this term has been used to describe the process of infection accompanied by the host's systemic inflammatory response. Based on that understanding, previous clin ical studies have been designed to include only patients with positive blood cultures [1, 2]. However, the frequent occurrence of a septic response without the demon stration of microorganisms in the circulation has led to a new definition and under standing of sepsis, mainly as the systemic response of the host to an often unde tectable microbiological or non-microbiological process [3]. The general consensus is that cytokines are central to the inflammatory response, particularly in sepsis. It is now known that not only Gram-negative but also Gram positive, viral, and fungal infections initiate the complex cascades of cytokine release. Probably the most important aspect of bacterial action is the release of toxic bacterial products. In particular endotoxin from Gram-negative bacteria (see chap ter by Schade) and super antigens (see chapter by Neumann and Holzmann), as well as pore-forming toxins [4] from Gram-positive bacteria, induce cytokine formation. The importance of this cytokine release is evident from both diagnostic and thera peutic (mostly experimental) studies, and the action of cytokines may be the key to our understanding of the pathophysiology of the sepsis syndrome.
Sepsis
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Author : Nancy Khardori
language : en
Publisher: Nova Science Publishers
Release Date : 2014
Sepsis written by Nancy Khardori and has been published by Nova Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014 with Septicemia categories.
The book discusses multiple aspects of sepsis syndrome seen in all age groups of patients and by all specialties in medicine. The syndrome is the aftermath of the dissemination of an infectious process into and through the blood stream. This allows the bacteria, bacterial products and cytokines to reach multiple organs, resulting in their dysfunction. In spite of the advances in supportive care and antibiotic therapy, the outcome of sepsis has not changed significantly. The inadequacies in the current diagnostic modalities and conflicting inconclusive results of investigations on novel treatments have contributed significantly to the lack of progress in the management of sepsis. Antibiotic overuse in and outside the intensive care unit driven by the lack of microbiological data and definitive diagnosis lends to the creation and transmission of antibiotic resistant bacteria, which has added to the challenges and poor outcomes of sepsis syndrome. The nine chapters in this book are authored by experts in various aspects of sepsis from North America, South America, Europe and Asia. State of the art information is provided in the areas of pathogenesis, epidemiology, diagnosis and management of sepsis. Each chapter has a contribution on the role of various evidence-based preventive strategies to reduce the incidence and subsequent poor outcomes of sepsis syndrome.
Sepsis And Non Infectious Systemic Inflammation
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Author : Jean-Marc Cavaillon
language : en
Publisher: John Wiley & Sons
Release Date : 2008-11-24
Sepsis And Non Infectious Systemic Inflammation written by Jean-Marc Cavaillon and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-11-24 with Science categories.
Providing definitions, clinical features and epidemiology, this handbook and reference adopts a comprehensive approach, describing in detail the various physiological systems involved. As such, it is the first to combine sepsis and non-infectious SIRS, reviewing both the biological and medical aspects of these two important syndromes. The whole is rounded off with a discussion of past, present and future therapies.
Core Concepts In Clinical Infectious Diseases Cccid
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Author : Carlos Franco-Paredes
language : en
Publisher: Academic Press
Release Date : 2016-03-16
Core Concepts In Clinical Infectious Diseases Cccid written by Carlos Franco-Paredes and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-03-16 with Medical categories.
Core Concepts in Clinical Infectious Diseases (CCID) provides medical students and researchers, infectious disease fellows, and practicing clinicians with key clinical concepts in the differential diagnosis and workup of infectious diseases. With the use of tables, charts, and problem-oriented medical diagnosis, it will provide a way of organizing and thinking about commonly seen clinical presentations of infectious diseases. Instead of discussing each disease process or any particular infectious process, this book will assist clinicians in seeing the forest and not focusing on the leaf. Graphs and tables have been constructed over 14 years of taking notes, teaching clinical infectious diseases, and discussing real clinical cases. This book is not about acquiring the structure of infectious diseases that is presented in classic textbooks of infectious disease; instead, it is about refining the process of putting the pieces together in clinical thinking to achieve an accurate clinical diagnosis and thus improved patient care. Assists the reader in connecting the dots (process of accumulating real-time knowledge) during the thinking process of clinical decision-making in the area of infectious diseases Uses tables and charts for easy understanding and application Contains a manual style that targets different audiences, such as medical students, hospital medicine specialists, outpatient internal medicine practitioners, infectious disease fellows in training, and practicing clinicians Provides an up-to-date discussion of core concepts in clinical infectious diseases
Spotlight On The Relationship Between Sepsis And Infection From Mechanisms To Therapy
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Author : Alessandro Russo
language : en
Publisher: Frontiers Media SA
Release Date : 2021-09-29
Spotlight On The Relationship Between Sepsis And Infection From Mechanisms To Therapy written by Alessandro Russo and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-09-29 with Medical categories.
The Immunology Of Sepsis Understanding Host Susceptibility Pathogenesis Of Disease And Avenues For Future Treatment
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Author : Luregn J. Schlapbach
language : en
Publisher: Frontiers Media SA
Release Date : 2020-08-19
The Immunology Of Sepsis Understanding Host Susceptibility Pathogenesis Of Disease And Avenues For Future Treatment written by Luregn J. Schlapbach and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-08-19 with categories.
We acknowledge the initiation and support of this Research Topic by the International Union of Immunological Societies (IUIS). We hereby state publicly that the IUIS has had no editorial input in articles included in this Research Topic, thus ensuring that all aspects of this Research Topic are evaluated objectively, unbiased by any specific policy or opinion of the IUIS.