Innovations And Implications In Molecular Diagnostics
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Innovations And Implications In Molecular Diagnostics
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Author : Qamre Alam
language : en
Publisher: CRC Press
Release Date : 2025-09-10
Innovations And Implications In Molecular Diagnostics written by Qamre Alam and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-09-10 with Medical categories.
This book introduces the field of molecular diagnostics, tracing its evolution from the earliest days of genetic research to cutting-edge advancements. It begins with a historical overview, setting the stage for an understanding of the foundational principles and techniques that underpin current practices in DNA analysis. It also provides the intricate details of various molecular techniques, such as advanced polymerase chain reaction (PCR) methods and next-generation sequencing, and their impact in the field of genetics and diagnostics. The book also explores the significant role of bioinformatics as the backbone of modern diagnostics and examines the changes brought about by high-throughput technologies and nanotechnology in molecular research and diagnostics. The importance of molecular imaging techniques in visualizing biological processes is discussed, along with the advancements in RNA analysis and their diagnostic implications. The book addresses the emerging fields of metabolomics and proteomics in molecular diagnostics and the transformative impact of artificial intelligence in this field. The book concludes with a thoughtful discussion on the ethical and regulatory considerations in molecular diagnostics. This book is intended for researchers and students of the fields of molecular diagnostics, biotechnology, and genomics. Key Features: Provides historical overview and recent advancements in the field of molecular diagnostics Explores foundational principles and advanced techniques in DNA analysis, including detailed insights into PCR methods Covers the applications and impact of next-generation sequencing in genetics and diagnostics Discusses the revolutionary influence of high-throughput technologies and nanotechnology in molecular research and diagnostics Examines the roles of metabolomics, proteomics, and artificial intelligence in molecular diagnostics
Innovations And Implications In Molecular Diagnostics
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Author : Qamre Alam
language : en
Publisher: CRC Press
Release Date : 2025-09-10
Innovations And Implications In Molecular Diagnostics written by Qamre Alam and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-09-10 with Medical categories.
This book provides a comprehensive exploration of the field of molecular diagnostics, tracing its evolution from the earliest days of genetic research to cutting-edge advancements. It begins with a historical overview, setting the stage for an understanding of the foundational principles and techniques that underpin current practices in DNA analysis. It also provides the intricate details of various molecular techniques, such as advanced polymerase chain reaction (PCR) methods and next-generation sequencing, and their impact in the field of genetics and diagnostics. The book also explores the significant role of bioinformatics as the backbone of modern diagnostics and examines the revolutionary changes brought about by high-throughput technologies and nanotechnology in molecular research and diagnostics. The importance of molecular imaging techniques in visualizing biological processes is discussed, along with the advancements in RNA analysis and their diagnostic implications. The book addresses the emerging fields of metabolomics and proteomics in molecular diagnostics and the transformative impact of artificial intelligence in this field. The book concludes with a thoughtful discussion on the ethical and regulatory considerations in molecular diagnostics. This book is intended for professionals and researchers in the fields of molecular diagnostics, biotechnology, and genomics. Key Features Provides a thorough historical overview and recent advancements in the field of molecular diagnostics. Explores foundational principles and advanced techniques in DNA analysis, including detailed insights into Polymerase Chain Reaction (PCR) methods. Covers the applications and impact of next-generation sequencing, emphasizing its role in genetics and diagnostics. Discusses the revolutionary influence of high-throughput technologies and nanotechnology in molecular research and diagnostics. Examines new areas like metabolomics, proteomics, and the transformative role of artificial intelligence in molecular diagnostics.
Molecular Diagnostics
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Author : George P. Patrinos
language : en
Publisher: Academic Press
Release Date : 2009-08-21
Molecular Diagnostics written by George P. Patrinos and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-08-21 with Science categories.
The 2e of Molecular Diagnostics, the only book dealing with diagnosis on a molecular level, discusses current molecular biological techniques used to identify the underlying molecular defects in inherited disease. The book delves further into the principle and brief description of the technique, followed by examples from the authors' own expertise. Contributors to the 2e are well-known experts in their field, and derive from a variety of disciplines, to ensure breadth and depth of coverage. Molecular Diagnostics, 2e , is a needed resource for graduate students, researchers, physicians and practicing scientists in molecular genetics and professionals from similar backgrounds working in diagnostic laboratories in academia or industry, as well as academic institutions and hospital libraries. - Deals exclusively with the currently used molecular biology techniques to identify the underlying molecular defect of inherited diseases - Includes pharmacogenetics and pharmacogenomics relating to new cancer therapies - Provies a comprehensive guide through emerging concepts and demonstrates how the available mutation screening technology can be implemented in diagnostic laboratories and provide better healthcare
Molecular Diagnostics Promises And Possibilities
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Author : Mousumi Debnath
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-01-29
Molecular Diagnostics Promises And Possibilities written by Mousumi Debnath and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-01-29 with Medical categories.
A rapid development in diverse areas of molecular biology and genetic engineering resulted in emergence of variety of tools. These tools are not only applicable to basic researches being carried out world over, but also exploited for precise detection of abnormal conditions in plants, animals and human body. Although a basic researcher is well versed with few techniques used by him/her in the laboratory, they may not be well acquainted with methodologies, which can be used to work out some of their own research problems. The picture is more blurred when the molecular diagnostic tools are to be used by physicians, scientists and technicians working in diagnostic laboratories in hospitals, industry and academic institutions. Since many of them are not trained in basics of these methods, they come across several gray areas in understanding of these tools. The accurate application of molecular diagnostic tools demands in depth understanding of the methodology for precise detection of the abnormal condition of living body. To meet the requirements of a good book on molecular diagnostics of students, physicians, scientists working in agricultural, veterinary, medical and pharmaceutical sciences, it needs to expose the reader lucidly to: Give basic science behind commonly used tools in diagnostics Expose the readers to detailed applications of these tools and Make them aware the availability of such diagnostic tools The book will attract additional audience of pathologists, medical microbiologists, pharmaceutical sciences, agricultural scientists and veterinary doctors if the following topics are incorporated at appropriate places in Unit II or separately as a part of Unit-III in the book. Molecular diagnosis of diseases in agricultural crops Molecular diagnosis of veterinary diseases. Molecular epidemiology, which helps to differentiate various epidemic strains and sources of disease outbreaks. Even in different units of the same hospital, the infections could be by different strains of the same species and the information becomes valuable for infection control strategies. Drug resistance is a growing problem for bacterial, fungal and parasitic microbes and the molecular biology tools can help to detect the drug resistance genes without the cultivation and in vitro sensitivity testing. Molecular diagnostics offers faster help in the selection of the proper antibiotic for the treatment of tuberculosis, which is a major problem of the in the developing world. The conventional culture and drug sensitivity testing of tuberculosis bacilli is laborious and time consuming, whereas molecular diagnosis offers rapid drug resistant gene detection even from direct clinical samples. The same approach for HIV, malaria and many more diseases needs to be considered. Molecular diagnostics in the detection of diseases during foetal life is an upcoming area in the foetal medicine in case of genetic abnormalities and infectious like TORCH complex etc. The book will be equally useful to students, scientists and professionals working in the field of molecular diagnostics.
Ensuring Innovation In Diagnostics For Bacterial Infection
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Author : Morel C.
language : en
Publisher: World Health Organization
Release Date : 2016-04-18
Ensuring Innovation In Diagnostics For Bacterial Infection written by Morel C. and has been published by World Health Organization this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-04-18 with Medical categories.
The inappropriate use of antibiotics is a primary cause of the ongoing increase in drug resistance amongst pathogenic bacteria. The resulting decrease in the efficacy of antibiotics threatens our ability to combat infectious diseases. Rapid point-of-care tests to identify pathogens and better target the appropriate treatment could greatly improve the use of antibiotics. Yet there are few such tests currently available or being developed despite the rapid pace of medical innovation. Clearly something is inhibiting the much-needed development of new and more convenient diagnostic tools. This study delineates priorities for developing diagnostics to improve antibiotic prescription and use with the goal of managing and curbing the expansion of drug resistance. It calls for new approaches particularly in the provision of diagnostic devices and in doing so outlines some of the inadequacies in health science and policy initiatives that have led to the dearth of such devices. The authors make the case that there is a clear and urgent need for innovation not only in the technology of diagnosis but also in public policy and medical practice to support the availability and use of better diagnostic tools. This book explores the complexities of the diagnostics market from the perspective of both supply and demand unearthing interesting bottlenecks some obvious some more subtle. It calls for a multifaceted and broad policy response and an overhaul of current practice so that the growth of bacterial resistance can be stemmed.
Innovative Governance Models For Emerging Technologies
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Author : Gary E Marchant
language : en
Publisher: Edward Elgar Publishing
Release Date : 2013-11-29
Innovative Governance Models For Emerging Technologies written by Gary E Marchant and has been published by Edward Elgar Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-29 with Technology & Engineering categories.
The unique characteristics of emerging technologies _ their diverse applications, the myriad concerns raised by new technologies, the need for public engagement, and the issue of effective coordination between governance players _ create the need for n
Biotech Innovations And Fundamental Rights
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Author : Roberto Bin
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-05-13
Biotech Innovations And Fundamental Rights written by Roberto Bin and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-05-13 with Law categories.
Biotechnology is a recognized research area that has increasingly advanced into new technologies and modern practices raising several legal, ethical and regulatory issues. The revolutionary speed of biotech innovations has had a significant impact on the protection of the rights of the individual. Fundamental rights provide a framework within which the justification of limitations and restrictions to biotechnology innovations and research results have to be assessed. The legal regulation of scientific research and scientific investigations impact more and more directly on the freedom of research and therapies as well as on the broad diffusion of knowledge. Closely related is also the debated question of the technological manipulation of life and the boundary of scientific knowledge with regard to the topical question of genetic invention patents and their side effects on access to scientific information and health care opportunities. Drawing on expertise from different disciplines, the volume comprises invited papers and plenary presentations given at the conference entitled “Biotech Innovations & Fundamental Rights” that took place on Januray 20-21 2011 at the Department of Juridical Sciences of the University of Ferrara. Each contribution covers a different aspect of the legal and scientific issues involved in regulation of biotechnology. In particular the focus of attention has been given to genetic research, genetic data, freedom of scientific research in genetics and biotech patents.
Molecular Allergy Diagnostics
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Author : Jörg Kleine-Tebbe
language : en
Publisher: Springer
Release Date : 2017-05-08
Molecular Allergy Diagnostics written by Jörg Kleine-Tebbe and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-05-08 with Medical categories.
This book, based on a recent German publication, offers an overview of basic data and recent developments in the groundbreaking field of molecular allergology. It comprehensively explores the origin and structure of single allergen molecules ("components") and their utility in improving the management of type I, IgE-mediated allergic reactions and disorders like allergic respiratory diseases, food allergies, and anaphylaxis. Highly specific testing, called component-resolved diagnostics, aims to identify and utilize single molecules. Over 200 single allergens from plant or animal sources have been applied to single or multiplex laboratory testing for the presence of allergen-specific IgE. This leap in assay sensitivity and specificity has led to three major advances in patient management: discrimination between primary allergic sensitization and complex cross-reactivity, recognition of IgE profiles for certain allergens and identification of patients most likely to benefit from allergen-specific immunotherapy. The book discusses in detail the benefits and limitations of this 21st century technology, and offers suggestions for the use of molecular allergology in routine clinical practice. It is a “must read” for physicians treating allergic patients as well as scientists interested in natural allergic molecules and their interactions with the human immune system.
Innovative Approaches In Diagnosis And Management Of Crop Diseases
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Author : R. K. Singh
language : en
Publisher: CRC Press
Release Date : 2021-09-28
Innovative Approaches In Diagnosis And Management Of Crop Diseases written by R. K. Singh and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-09-28 with Technology & Engineering categories.
This book is the second of the 3-volume Innovative Approaches in Diagnosis and Management of Crop Diseases, which provides an abundance of new research and information on major diseases of various crops along with new techniques and technology for the detection of plant pathogens along with appropriate management strategies. Divided into three volumes and with chapters written by renowned and expert scientists working in different areas of plant pathology, the volumes cover important diseases of crops, incited by bacteria, fungi, viruses, viroids, phytoplasma, and nematodes. It addresses these disease challenges to commercial field and horticultural crops and their management. Innovative Approaches in Diagnosis and Management of Crop Diseases: Volume 2 focuses on recent advances in diagnosis, detection, and management of diseases of specific crops, such as cotton, sesame, rice, wheat, millet, maize, field pea and pigeonpea, ginger and turmeric, guava, aonla, and vegetable cruciferous crops. Key features: Presents diverse research of leading plant pathologists on detection, diagnosis, and management of crop diseases Shares innovative and emerging techniques for diagnosis and management of major plant diseases Covers a vast array of important crops and their diseases Volume 1 of this multi-volume set focuses on the Mollicute class of bacteria. It looks at the detection, diagnosis, and management of phytoplasma diseases and viroids, CRISPR-Cas9 genome editing in plants for virus resistance, next-generation sequencing technologies, and more, while Volume 3 reviews the advances in the uses of nanomolecules and biocontrol agents. Diagnosis and management of biotic stresses play a pivotal role in efficient agriculture production, and together, these volumes of Innovative Approaches in Diagnosis and Management of Crop Diseases provide informative reviews of crucial research to effectively advance the detection, diagnosis, and management of crop diseases.
Science Technology And Innovation In Brics Countries
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Author : Swapan Kumar Patra
language : en
Publisher: Taylor & Francis
Release Date : 2020-06-09
Science Technology And Innovation In Brics Countries written by Swapan Kumar Patra and has been published by Taylor & Francis this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-06-09 with Business & Economics categories.
The term BRICS (Brazil, Russia, India, China and South Africa) is gaining global attention both in scholarly and popular discourse. BRICS countries are crucial in terms of their vast areas, huge population and have massive economic potential. These countries are also categorized as developing countries and are aspiring to be considered as developed countries. There is commonality among these countries in that they have similar issues and problems, which may require common solutions. Science, Technology and Innovation in BRICS Countries examines whether more emphasis on Science Technology and Innovation (STI) capability building could be the solution to these countries’ economic upgradation and poverty reduction. This book is a collection of various Science Technology and Innovation (STI) issues of BRICS economics, and will be of interest to general readers, scholars working in this field, as well as policy makers all over the globe. The contributions come from various scholars across the globe who have published their BRICS economics research in a special issue of the African Journal of Science, Technology, Innovation and Development.