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Insights Into Brown Adipose Tissue Functions And Browning Phenomenon


Insights Into Brown Adipose Tissue Functions And Browning Phenomenon
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Insights Into Brown Adipose Tissue Functions And Browning Phenomenon


Insights Into Brown Adipose Tissue Functions And Browning Phenomenon
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Author : Rita De Matteis
language : en
Publisher: Frontiers Media SA
Release Date : 2020-04-20

Insights Into Brown Adipose Tissue Functions And Browning Phenomenon written by Rita De Matteis and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-04-20 with categories.




Novel Insights Into Adipose Cell Functions


Novel Insights Into Adipose Cell Functions
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Author : Karine Clément
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-09-14

Novel Insights Into Adipose Cell Functions written by Karine Clément and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-09-14 with Medical categories.


Obesity is a disease of society and economic transition spreading at an epidemic pace throughout the world. According to the World Health Organization, obesity is defined as an increased or abnormal accumulation of body fat mass to the extent that individual’s health will be negatively affected. Overweight is thus being considered as top at risk condition in the world and it is mandatory to identify the physiopathological causes involved in adipose tissue enlargement and related metabolic and cardiovascular health disorders.This volume provides the most up to date insights into the biology of a complex endocrine organ: the adipose tissue.



Novel Insights Into Adipose Cell Functions


Novel Insights Into Adipose Cell Functions
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Author : Karine Clément
language : en
Publisher:
Release Date : 2010

Novel Insights Into Adipose Cell Functions written by Karine Clément and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010 with categories.


Obesity is considered as top at risk condition in the world and it is mandatory to identify the physiopathological causes involved in adipose tissue enlargement and related metabolic and cardiovascular health disorders. Environmental, behavioural, genetic, epigenetic and multiple biological factors interact to cause obesity. In this context adipose tissue depots have been under focus in the last decades and pivotal concepts have emerged from the studies of their complex biology. While the white adipose tissue (WAT) is the main energy repository in the body (mobilizing fatty acids according to body needs) thanks to white adipocyte properties, WAT is also a multicellular organ communicating with other body organs (brain, muscles, liver, pancreas, heart, vessels, etc...) via complex networks of endocrine signals. The discovery of leptin in 1994 led to recognize WAT as a master organ at the crossroad of a myriad of physiological interactions to control food intake, energy balance, glucose and lipid metabolism, immunity and reproduction. The phenotype, amount and biology of each WAT component are profoundly altered in human obesity. Adipose plasticity also accounts for the extraordinary capacity of adipose precursors to differentiate into functional cardiomyocytes, osteoblasts, haematopoietic and neural cells, a convenient property for regenerative medicine. Finally, while initially thought to exert a negligible role in humans, the discovery of brown adipose tissue in adults stimulates a novel interest for this tissue with high capacity to oxidize fatty acids.



Novel Regulatory Mechanisms Behind Thermogenesis Of Brown And Beige Adipocytes


Novel Regulatory Mechanisms Behind Thermogenesis Of Brown And Beige Adipocytes
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Author : Rubén Cereijo
language : en
Publisher: Frontiers Media SA
Release Date : 2023-09-19

Novel Regulatory Mechanisms Behind Thermogenesis Of Brown And Beige Adipocytes written by Rubén Cereijo and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-09-19 with Medical categories.




Tissue Specific Cell Signaling


Tissue Specific Cell Signaling
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Author : Joana Vieira Silva
language : en
Publisher: Springer Nature
Release Date : 2020-05-29

Tissue Specific Cell Signaling written by Joana Vieira Silva and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-05-29 with Medical categories.


Signal transduction comprises the intracellular biochemical signals which induce the appropriate cell response to an external stimulus. The players in signal transduction are diverse, from small molecules as first messengers, to proteins, receptors, transcription factors, among many others. The different signaling pathways and the crosstalk between them originates the unique signaling profile of every cell type in the human body. The cell signaling specificity depends on several aspects including protein composition, subcellular localization and complexes and gene promoters. This textbook provides a comprehensive overview of the specific signaling pathways on a variety of human tissues. This information can be of great value for health science researchers, professionals and students to understand key pathways for tissue-specific functions in the plethora of signals, signals receptors, transducers and effectors. Chapter 3 and 15 are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.



Obesity And Diabetes


Obesity And Diabetes
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Author : Joel Faintuch
language : en
Publisher: Springer Nature
Release Date : 2020-12-14

Obesity And Diabetes written by Joel Faintuch and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-12-14 with Medical categories.


Now in its second edition, this comprehensive handbook provides a state-of-the-art overview of recent advances in drug and non-drug therapies for obesity and diabetes. It also addresses major comorbidities, covering topics such as, cardiovascular diseases, renal and neuropsychiatric disorders, appetite control and micro RNAs. Special attention is also devoted to pediatric care, including the latest recommendations for therapy and prevention. Obesity and type 2 diabetes are among the top global health-care budget concerns worldwide and impact professional practice at all levels: in hospitals, clinics and physicians’ offices alike. They prominently feature in headlines, and virtually no family, community or country is exempt from their protean, deleterious consequences. Furthermore, given the multiple intersections in their pathways, they often go hand in hand. The good news is that scientific advances in all fields, including genomics, metabolomics, lipidomics and microbiomics, are increasing our understanding of these two disease areas. At the same time, artificial intelligence, machine learning, mobile health and advanced implantable and external devices are rendering prevention and management more available, safe and cost-effective. In addition, bariatric and metabolic surgery has evolved from a niche specialty to an officially endorsed option for several modalities of obesity and diabetes. This book presents the latest lifestyle, pharmacological, surgical and non-surgical treatment options, including endoscopic intervention and cell therapy. Objectively reviewing natural and artificial sweeteners and critically examining issues such as public health initiatives, government mandated taxes for unhealthy foods and environmental planning, no stone is left unturned in gathering the latest practical information. As such, the book will appeal to seasoned specialists, as well as students and healthcare professionals in training.



The Adipose Organ


The Adipose Organ
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Author : Saverio Cinti
language : en
Publisher:
Release Date : 1999

The Adipose Organ written by Saverio Cinti and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999 with Medical categories.




Adipose Tissue In Health And Disease


Adipose Tissue In Health And Disease
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Author : Todd Leff
language : en
Publisher: John Wiley & Sons
Release Date : 2010-03-19

Adipose Tissue In Health And Disease written by Todd Leff and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-03-19 with Science categories.


This timely and most comprehensive reference available on the topic covers all the different aspects vital in the fight against the global obesity epidemic. Following a look at adipose tissue development and morphology, the authors go on to examine its metabolic and endocrine functions and its role in disease. The final section deals with comparative and evolutionary aspects of the tissue. The result is an essential resource for cell and molecular biologists, physiologists, biochemists, pharmacologists, and those working in the pharmaceutical industry.



Multidisciplinary Approach To Obesity


Multidisciplinary Approach To Obesity
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Author : Andrea Lenzi
language : en
Publisher: Springer
Release Date : 2014-11-18

Multidisciplinary Approach To Obesity written by Andrea Lenzi and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-11-18 with Medical categories.


This book describes in detail the multidisciplinary management of obesity, providing readers with a thorough understanding of the rationale for a multidisciplinary approach and with the tools required to implement it effectively. The emphasis is on a translational approach, starting from basic concepts and fundamental mechanisms of the pathology and clinical morbidity. Experts in the field discuss the full range of relevant topics, including the significance of physical exercise, psychological issues, nutritional strategies, pharmacological options and bariatric surgery. Put another way, the book covers all aspects from the bench to the bedside. Physicians, scientists and postgraduate students will all find it to be invaluable in understanding the causes and optimal management of obesity, which has rapidly become a major public health problem.



Mechanisms Of Insulin Action


Mechanisms Of Insulin Action
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Author : Alan R. Saltiel
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-10-05

Mechanisms Of Insulin Action written by Alan R. Saltiel and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-10-05 with Medical categories.


More than 18 million people in the United States have diabetes mellitus, and about 90% of these have the type 2 form of the disease. This book attempts to dissect the complexity of the molecular mechanisms of insulin action with a special emphasis on those features of the system that are subject to alteration in type 2 diabetes and other insulin resistant states. It explores insulin action at the most basic levels, through complex systems.