Intercellular Signaling In Development And Disease
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Intercellular Signaling In Development And Disease
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Author : Edward A. Dennis
language : en
Publisher: Academic Press
Release Date : 2011-04-08
Intercellular Signaling In Development And Disease written by Edward A. Dennis and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-04-08 with Science categories.
"Cell signaling, which is also often referred to as signal transduction or, in more specialized cases, transmembrane signaling, is the process by which cells communicate with their environment and respond temporally to external cues that they sense there. All cells have the capacity to achieve this to some degree, albeit with a wide variation in purpose, mechanism, and response. At the same time, there is a remarkable degree of similarity over quite a range of species, particularly in the eukaryotic kingdom, and comparative physiology has been a useful tool in the development of this field. The central importance of this general phenomenon (sensing of external stimuli by cells) has been appreciated for a long time, but it has truly become a dominant part of cell and molecular biology research in the past three decades, in part because a description of the dynamic responses of cells to external stimuli is, in essence, a description of the life process itself. This approach lies at the core of the developing fields of proteomics and metabolomics, and its importance to human and animal health is already plainly evident"--Provided by publisher.
Wnt Signaling In Development And Disease
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Author :
language : en
Publisher: Elsevier
Release Date : 2023-03-24
Wnt Signaling In Development And Disease written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-03-24 with Science categories.
Wnt Signaling in Stem Cells, Development and Regeneration, Volume 153, delves into the biology of Wnt signaling in a wide variety of model organisms. Since their first identification in 1982, Wnt proteins and their downstream effectors have captivated the attention of many researchers in a variety of fields, including developmental biology, cell signaling, structural biology, stem and cancer cell biology and regeneration. Wnt signaling, along with a small number of highly conserved signaling modules including the Hedgehog, FGF, BMP, RA and Notch pathways, orchestrates morphogenesis across all metazoans. Readers will find information on recent discoveries in the Wnt field, including interactions between Wnt and other signaling pathways, and tools and technologies to interrogate the complexity of Wnt signaling. Other chapters cover Wnt signaling in Xenopus neural development, Wnt signaling in hematopoietic stem cell development, Wnt signaling and the maintenance and regeneration of the gut epithelium, Wnt signaling in the skeleton as a basis for Wnt-based regenerative medicine, and Non-canonical Wnt5a-Ror signaling: Insights from human congenital disorders and cancer. - Presents newest findings on the role of Wnt signaling in a variety of tissues and organisms - Illustrates the diverse actions of Wnt signaling in development and disease - Highlight tools and technologies to interrogate Wnt signaling in any biological system
Intercellular Signaling In Development And Disease
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Author : Edward A. Dennis
language : en
Publisher: Academic Press
Release Date : 2011-04-05
Intercellular Signaling In Development And Disease written by Edward A. Dennis and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-04-05 with Science categories.
Required reading for anyone involved in cell signaling research with articles written and edited by experts in the field. This title covers disease states such as lymphoid leukemia, breast cancer, pulmonary fibrosis, systemic sclerosis, andinflammatory bowel disease, along with up-to-date research on signaling systems and mutations intranscription factors that provide new targets for treating disease. - Articles written and edited by experts in the field - Thematic volume covering disease states such as lymphoid leukemia, breast cancer, pulmonary fibrosis, systemic sclerosis, and inflammatory bowel disease - Up-to-date research on signaling systems and mutations in transcription factors that provide new targets for treating disease
An Introduction To Interdisciplinary Toxicology
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Author : Carey N. Pope
language : en
Publisher: Academic Press
Release Date : 2020-02-18
An Introduction To Interdisciplinary Toxicology written by Carey N. Pope and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-02-18 with Technology & Engineering categories.
An Introduction to Interdisciplinary Toxicology: From Molecules to Man integrates the various aspects of toxicology, from "simple molecular systems, to complex human communities, with expertise from a spectrum of interacting disciplines. Chapters are written by specialists within a given subject, such as a chemical engineer, nutritional scientist, or a microbiologist, so subjects are clearly explained and discussed within the toxicology context. Many chapters are comparative across species so that students in ecotoxicology learn mammalian toxicology and vice versa. Specific citations, further reading, study questions, and other learning features are also included. The book allows students to concurrently learn concepts in both biomedical and environmental toxicology fields, thus better equipping them for the many career opportunities toxicology provides. This book will also be useful to those wishing to reference how disciplines interact within the broad field of toxicology. - Covers major topics and newer areas in toxicology, including nanotoxicology, Tox21, epigenetic toxicology, and organ-specific toxicity - Includes a variety of perspectives to give a complete understanding of toxicology - Written by specialists within each subject area, e.g., a chemical engineer, to ensure concepts are clearly explained
Cellular Adhesion In Development And Disease
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Author :
language : en
Publisher: Academic Press
Release Date : 2015-02-27
Cellular Adhesion In Development And Disease written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-02-27 with Science categories.
Cell adhesion is a fundamental determinant of embryonic development and organogenesis. Cellular Adhesion in Development and Disease, volume 112 in Current Topics in Developmental Biology, comprehensively surveys current developments in understanding how adhesion systems affect organismal development. Topics covered include nectins, nectin-like molecules, and afadin in development; cadherin adhesion, signaling, and morphogenesis; endothelial cell junctions; epidermal development and barrier formation; and more. - This book surveys current understanding of how adhesion systems affect organismal development
Non Genetic Heterogeneity In Development And Disease
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Author : Mohit Kumar Jolly
language : en
Publisher: Frontiers Media SA
Release Date : 2021-11-01
Non Genetic Heterogeneity In Development And Disease written by Mohit Kumar Jolly and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-01 with Science categories.
Amphibian Models Of Development And Disease
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Author :
language : en
Publisher: Academic Press
Release Date : 2021-05-30
Amphibian Models Of Development And Disease written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-05-30 with Science categories.
Amphibian Models of Development and Disease, Volume 145 in the Current Topics in Developmental Biology series, highlights new advances in the field written by an international board of experts. New chapters in this release include Building a ciliated epithelium: Transcriptional regulation and radial intercalation of multiciliated cells, Biomechanics of Amphibian Morphogenesis, Planar cell polarity during neural tube closure, Xenopus neural crest and its relevance to human disease, Endoderm organogenesis, From egg to embryo in marsupial frogs, Evo-devo lessons from the analysis of Xenopus genomes, Transcriptional regulation during zygotic genome activation, Proteomics and metabolomics for cell lineage analysis in frog embryos, and more. - Provides the authority and expertise of leading contributors from an international board of authors - Presents the latest release in the Current Topics in Developmental Biology series - Includes the latest information on Amphibian Models of Development and Disease
Gap Junctions In Development And Disease
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Author : Elke Winterhager
language : en
Publisher: Springer Science & Business Media
Release Date : 2005-07-19
Gap Junctions In Development And Disease written by Elke Winterhager and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-07-19 with Health & Fitness categories.
Communication between cells via intercellular channels – gap junctions – appears essential to certain developmental processes and appropriate organ function. Gap Junctions in Development and Disease aims to describe the molecular events underlying impaired development and disease. Beginning with a comprehensive review of various mouse and human genes encoding the channel-forming connexins, later chapters describe several connexin mutations associated with human diseases such as hereditary deafness and female infertility. Erroneous signaling mediated by the interaction of mutant connexins with other proteins, thought to be responsible for dysfunction of organs such as heart, muscle, brain, skin, lens, placenta, and endocrine tissue in both mice and men, is also addressed. Although the question of why some mutations in gap-junction proteins lead to specific phenotypes remains to be answered, the reviews in this book provide an intriguing insight into the future direction of this research field.
Etiology And Morphogenesis Of Congenital Heart Disease
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Author : Toshio Nakanishi
language : en
Publisher: Springer
Release Date : 2016-06-24
Etiology And Morphogenesis Of Congenital Heart Disease written by Toshio Nakanishi and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-06-24 with Medical categories.
This volume focuses on the etiology and morphogenesis of congenital heart diseases. It reviews in detail the early development and differentiation of the heart, and later morphologic events of the cardiovascular system, covering a wide range of topics such as gene functions, growth factors, transcription factors and cellular interactions that are implicated in cardiac morphogenesis and congenital heart disease. This book also presents recent advances in stem cell and cell sheet tissue engineering technologies which have the potential to provide novel in vitro disease models and to generate regenerative paradigms for cardiac repair and regeneration. This is the ideal resource for physician scientists and investigators looking for updates on recent investigations on the origins of congenital heart disease and potential future therapies.
Epigenomic And Epitranscriptomic Basis Of Development And Human Disease
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Author : Yujing Li
language : en
Publisher: Frontiers Media SA
Release Date : 2023-04-05
Epigenomic And Epitranscriptomic Basis Of Development And Human Disease written by Yujing Li and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-04-05 with Science categories.