Epigenomic And Epitranscriptomic Basis Of Development And Human Disease
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Epigenomic And Epitranscriptomic Basis Of Development And Human Disease
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Author : Yujing Li
language : en
Publisher: Frontiers Media SA
Release Date : 2023-04-05
Epigenomic And Epitranscriptomic Basis Of Development And Human Disease written by Yujing Li and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-04-05 with Science categories.
Epigenomics
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Author : Gurbachan Singh Miglani
language : en
Publisher: I K International Pvt Ltd
Release Date : 2023-06-13
Epigenomics written by Gurbachan Singh Miglani and has been published by I K International Pvt Ltd this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-06-13 with Medical categories.
Epigenomics deals in detail with the concepts, principles, procedures, developments, limitations, advantages, applications and future prospects of different areas of epigenomics in a comprehensive manner. It provides concise yet complete knowledge on the many aspects of the basic and most recent methods and applications in epigenomics, a branch of epigenetics that deals with the mechanisms such as DNA modifications, histone modifications, RNA modifications, small and long non-coding RNAs, chromatin remodeling, which are involved in epigenetic control of gene expression without involving variations in DNA sequences. These regulatory mechanisms lead to phenotypic variations. These epigenetic mechanisms can be exploited for crop improvement and cure of human diseases. Epigenomics strives to understand the role of epigenetic marks (chemical tags) in the development of phenotype. This understanding provides epigeneticists to apply epigenomics in medicine and agriculture. Self-explanatory adequately labelled figures have been the special emphasis throughout. This book is primarily designed for senior undergraduate and graduate level (M.Sc. and Ph.D.) students studying epigenetics in conventional, agricultural and medicinal universities. This book will be a useful reference text for teachers and researcher in any discipline of life sciences, agricultural sciences, medicine, and biotechnology.
Epitranscriptomics
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Author : Stefan Jurga
language : en
Publisher: Springer Nature
Release Date : 2021-07-28
Epitranscriptomics written by Stefan Jurga and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-07-28 with Science categories.
This book reviews a novel and exciting field of cellular and molecular biology called epitranscriptomics, which focuses on changes in an organism’s cells resulting from the posttranscriptional modification of cellular RNA. RNA-binding proteins (RBPs) play a crucial role in these posttranscriptional modifications and also support several cellular processes necessary for maintaining RNA homeostasis. Exploring the mechanisms underlying RNA modifications and RBP function is an emerging area of biomedical research, taking the study of gene regulation a step beyond epigenetics. This book reveals that the RNA molecule is not just an information-carrying molecule with some secondary structures. Accordingly, how RNA is modified, regulated, packaged, and controlled is an important aspect. Leading experts address questions such as where the over 170 distinct posttranscriptional RNA modifications are located on the genome, what percentage of mRNAs and noncoding RNAs these modifications include, and how an RNA modification impacts a person’s biology. In closing, the book reviews the role of RNA modifications and RBPs in a variety of diseases and their pathogenesis. Addressing some of the most exciting challenges in epitranscriptomics, this book provides a valuable and engaging resource for researchers in academia and industry studying the phenomena of RNA modification.
Epigenetic Regulation In Overcoming Chemoresistance
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Author : Chunfu Wu
language : en
Publisher: Academic Press
Release Date : 2021-06-26
Epigenetic Regulation In Overcoming Chemoresistance written by Chunfu Wu and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-06-26 with Science categories.
Epigenetic Regulation in Overcoming Chemoresistance, Volume 19, explains how epigenetic agents can enhance the chemotherapy sensitivity of diverse types of cancers. The book provides a comprehensive delineation and the recent development of the scientific studies on the epigenetic regulation in enhancing chemo-sensitivity. In addition, it discusses several topics such as DNA methyltransferase inhibitors (DNMTi), Histone deacetylases inhibitors (HDACi), Histone lysine demethylases inhibitors (HDMi), Histone lysine methyltransferases inhibitors (HMTi) and drugs regulating the microRNA, long non-coding RNA (lncRNA) or RNA methylation. Finally, recent and future developments of the field of epigenetic regulation are explored. This is a valuable resource for cancer researchers, clinicians, graduate students and several members of biomedical field who are interested in learning about epigenetic regulation methods to reverse chemo-resistance in cancers. - Presents detailed diagrams of the mechanisms of epigenetic regulation for easy consult - Encompasses multiple clinical trial summary diagrams to help readers quickly and clearly get information from clinical trials - Provides future perspectives in each section to inspire readers to use epigenetic regulation to overcome chemo-resistance
Epigenetic Processes And Evolution Of Life
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Author : Jana Švorcová
language : en
Publisher: CRC Press
Release Date : 2019-01-15
Epigenetic Processes And Evolution Of Life written by Jana Švorcová and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-01-15 with Science categories.
The book covers the possible story of emergence of life and its subsequent evolution, emphasizing the necessary evolutionary step negotiation of a common "language set" which kept all inhabitants in the biosphere together, ensuring a basic level of understanding among them. The book focuses on "protocols of communication" (both genetic and epigenetic) representing norms shared and understood across the whole biosphere, enabling a plethora of holobiotic relationships. Cooperative nature of organismal evolution and epigenetic processes as a major force in evolution are also covered. Topics discussed are illustrated in detail on selected casuistics.
Application Of Epigenomics Data To Improve Human And Livestock Health
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Author : Xiao Wang
language : en
Publisher: Frontiers Media SA
Release Date : 2023-07-21
Application Of Epigenomics Data To Improve Human And Livestock Health written by Xiao Wang and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-07-21 with Science categories.
Role Of Epigenetic Regulators In The Initiation Progression And Metastasis Of Cancer
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Author : Ritu Kulshreshtha
language : en
Publisher: Frontiers Media SA
Release Date : 2022-11-30
Role Of Epigenetic Regulators In The Initiation Progression And Metastasis Of Cancer written by Ritu Kulshreshtha and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-11-30 with Science categories.
Rna Modifications And Epitranscriptomics
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Author : Xiao Han
language : en
Publisher: Frontiers Media SA
Release Date : 2022-05-05
Rna Modifications And Epitranscriptomics written by Xiao Han and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-05-05 with Science categories.
Epigenetic Metabolic And Transcriptional Regulation Of Immune Cell Plasticity And Functions In Cancer And Non Cancer Diseases
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Author : Yun Dai
language : en
Publisher: Frontiers Media SA
Release Date : 2023-10-25
Epigenetic Metabolic And Transcriptional Regulation Of Immune Cell Plasticity And Functions In Cancer And Non Cancer Diseases written by Yun Dai and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-10-25 with Medical categories.
Systems Analysis Of Human Multigene Disorders
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Author : Natalia Maltsev
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-29
Systems Analysis Of Human Multigene Disorders written by Natalia Maltsev and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-29 with Science categories.
Understanding the genetic architecture underlying complex multigene disorders is one of the major goals of human genetics in the upcoming decades. Advances in whole genome sequencing and the success of high throughput functional genomics allow supplementing conventional reductionist biology with systems-level approaches to human heredity and health as systems of interacting genetic, epigenetic, and environmental factors. This integrative approach holds the promise of unveiling yet unexplored levels of molecular organization and biological complexity. It may also hold the key to deciphering the multigene patterns of disease inheritance.