Rna Modifications And Epitranscriptomics
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Rna Modifications And Epitranscriptomics
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Author : Xiao Han
language : en
Publisher: Frontiers Media SA
Release Date : 2022-05-05
Rna Modifications And Epitranscriptomics written by Xiao Han and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-05-05 with Science categories.
Rna Modifications And Epitranscriptomics Volume Ii
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Author : Giovanni Nigita
language : en
Publisher: Frontiers Media SA
Release Date : 2023-06-30
Rna Modifications And Epitranscriptomics Volume Ii written by Giovanni Nigita and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-06-30 with Science categories.
Computational Epitranscriptomics Bioinformatic Approaches For The Analysis Of Rna Modifications
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Author : Mattia Pelizzola
language : en
Publisher: Frontiers Media SA
Release Date : 2021-02-02
Computational Epitranscriptomics Bioinformatic Approaches For The Analysis Of Rna Modifications written by Mattia Pelizzola and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-02-02 with Science categories.
Epitranscriptomics
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Author : Stefan Jurga
language : en
Publisher: Springer Nature
Release Date : 2021-07-28
Epitranscriptomics written by Stefan Jurga and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-07-28 with Science categories.
This book reviews a novel and exciting field of cellular and molecular biology called epitranscriptomics, which focuses on changes in an organism’s cells resulting from the posttranscriptional modification of cellular RNA. RNA-binding proteins (RBPs) play a crucial role in these posttranscriptional modifications and also support several cellular processes necessary for maintaining RNA homeostasis. Exploring the mechanisms underlying RNA modifications and RBP function is an emerging area of biomedical research, taking the study of gene regulation a step beyond epigenetics. This book reveals that the RNA molecule is not just an information-carrying molecule with some secondary structures. Accordingly, how RNA is modified, regulated, packaged, and controlled is an important aspect. Leading experts address questions such as where the over 170 distinct posttranscriptional RNA modifications are located on the genome, what percentage of mRNAs and noncoding RNAs these modifications include, and how an RNA modification impacts a person’s biology. In closing, the book reviews the role of RNA modifications and RBPs in a variety of diseases and their pathogenesis. Addressing some of the most exciting challenges in epitranscriptomics, this book provides a valuable and engaging resource for researchers in academia and industry studying the phenomena of RNA modification.
Epitranscriptomics The Novel Rna Frontier
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Author : Giovanni Nigita
language : en
Publisher: Frontiers Media SA
Release Date : 2019-01-31
Epitranscriptomics The Novel Rna Frontier written by Giovanni Nigita and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-01-31 with categories.
Following the formulation of the central dogma of molecular biology and the later discovery of classes of non-coding RNAs, the primary focus of Genetics was essentially on variation of DNA aiming at elucidating biological pathways perturbed in diseases. Recently, extensive attention has shifted towards the study of posttranscriptional RNA modifications occurring in both protein-coding as well as non-coding RNAs, revealing a novel and finer layer of complexity in gene regulation. This, in turn, has led to the birth of the novel field of ‘Epitranscriptomics’. The recent increase of applications of high-throughput sequencing technology (HTS) has allowed the unprecedented opportunity to identify on a transcriptome-wide scale, millions of RNA modifications in human genes, counting today more than 140 distinct types such as: methylation (e.g. m6A, m1A, m5C, hm5C, 2’OMe) methylation (e.g. m6A, m1A, m5C, hm5C, 2’OMe), pseudourylation (?), deamination (e.g. A-to-I RNA editing). The scope of this Research Topic was to collect both reviews and research articles addressing the wet lab approaches and bioinformatics methodologies necessary to aid in the identification of novel RNA modifications and characterization of their biological functions. Among the articles embracing the aim of the Research Topic, we have collected four original research and methods articles, five reviews, and a technology article.
Epitranscriptomics
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Author : Narendra Wajapeyee
language : en
Publisher:
Release Date : 2018
Epitranscriptomics written by Narendra Wajapeyee and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018 with Transcription factors categories.
Rna Modifications
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Author : Mary McMahon
language : en
Publisher: Humana
Release Date : 2021-06-04
Rna Modifications written by Mary McMahon and has been published by Humana this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-06-04 with Science categories.
This detailed book describes some of the most recent advances and up-to-date methodologies to detect, quantify, analyze, and elucidate the biological function of different types of RNA modifications. Importantly, the methodologies and tools described herein can be applied to a wide variety of organisms and can be used to address biological and clinical questions. Beginning with a section on bioinformatics tools, the collection continues with sections on detecting RNA modifications using Nanopore direct RNA sequencing, next-generation sequencing approaches, qPCR- and molecular biology-based methods, mass spectrometry- and NMR-based methods, as well as approaches to assess kinetics, determinants, and functions of RNA modifications. Written for the highly successful Methods in Molecular Biology series style, chapters include introduction to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, RNA Modifications: Methods and Protocols serves as an ideal guide for those working directly in the fields of epitranscriptomics and post-transcriptional gene regulation, as well as for scientists and clinicians interested in bioinformatic tools to study RNA modifications and techniques to dissect their roles in physiology and disease. /divChapter 20 is available open access under a CC BY 4.0 license.
Role Of Rna Modification In Disease
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Author : Emanuele Buratti
language : en
Publisher: Frontiers Media SA
Release Date : 2020-02-03
Role Of Rna Modification In Disease written by Emanuele Buratti and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-02-03 with categories.
Rna Modification
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Author :
language : en
Publisher: Academic Press
Release Date : 2015-12-11
Rna Modification written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-12-11 with Medical categories.
RNA Modification provides a useful examination of the science and its role in biological regulation, the current frontier of life science research, and includes various RNA modications and their role in gene expression. It represents the most up-to-date knowledge and protocols available today. Dynamic RNA modifications and their roles in biological regulation are the current frontier of life science research This volume of Methods in Enzymology represents up to date knowledge and protocols
Rna Modification Enzymes
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Author :
language : en
Publisher: Academic Press
Release Date : 2021-09-11
Rna Modification Enzymes written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-09-11 with Science categories.
RNA Modification Enzymes, Volume 659 in the Methods in Enzymology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of related topics, including Locating chemical modifications in RNA sequences through ribonucleases and LC-MS based analysis, Development of RNA modification mapping pipelines for high-throughput sequencing approaches, AlkAniline-Seq for high-resolution mapping RNA m7G and m3C modifications, Facile detection of RNA phospho-methylation in cells, Detection and analysis of glycosylated queuosine modifications, A comprehensive pipeline for analysis of RNA 3’-end modification, Analysis of the epitranscriptome with ion-pairing reagent free oligonucleotide mass spectrometry, and more. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Methods in Enzymology series Updated release includes the latest information on the RNA Modification Enzymes