Introduction To Bioinformatics With R
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Introduction To Bioinformatics With R
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Author : Edward Curry
language : en
Publisher: CRC Press
Release Date : 2020-11-02
Introduction To Bioinformatics With R written by Edward Curry and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-11-02 with Science categories.
In biological research, the amount of data available to researchers has increased so much over recent years, it is becoming increasingly difficult to understand the current state of the art without some experience and understanding of data analytics and bioinformatics. An Introduction to Bioinformatics with R: A Practical Guide for Biologists leads the reader through the basics of computational analysis of data encountered in modern biological research. With no previous experience with statistics or programming required, readers will develop the ability to plan suitable analyses of biological datasets, and to use the R programming environment to perform these analyses. This is achieved through a series of case studies using R to answer research questions using molecular biology datasets. Broadly applicable statistical methods are explained, including linear and rank-based correlation, distance metrics and hierarchical clustering, hypothesis testing using linear regression, proportional hazards regression for survival data, and principal component analysis. These methods are then applied as appropriate throughout the case studies, illustrating how they can be used to answer research questions. Key Features: · Provides a practical course in computational data analysis suitable for students or researchers with no previous exposure to computer programming. · Describes in detail the theoretical basis for statistical analysis techniques used throughout the textbook, from basic principles · Presents walk-throughs of data analysis tasks using R and example datasets. All R commands are presented and explained in order to enable the reader to carry out these tasks themselves. · Uses outputs from a large range of molecular biology platforms including DNA methylation and genotyping microarrays; RNA-seq, genome sequencing, ChIP-seq and bisulphite sequencing; and high-throughput phenotypic screens. · Gives worked-out examples geared towards problems encountered in cancer research, which can also be applied across many areas of molecular biology and medical research. This book has been developed over years of training biological scientists and clinicians to analyse the large datasets available in their cancer research projects. It is appropriate for use as a textbook or as a practical book for biological scientists looking to gain bioinformatics skills.
R Programming For Bioinformatics
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Author : Robert Gentleman
language : id
Publisher: CRC Press
Release Date : 2008-07-14
R Programming For Bioinformatics written by Robert Gentleman and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-07-14 with Mathematics categories.
Due to its data handling and modeling capabilities as well as its flexibility, R is becoming the most widely used software in bioinformatics. R Programming for Bioinformatics explores the programming skills needed to use this software tool for the solution of bioinformatics and computational biology problems.Drawing on the author's first-hand exper
Getting Started With R
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Author : Andrew P. Beckerman
language : en
Publisher: Oxford University Press
Release Date : 2017
Getting Started With R written by Andrew P. Beckerman and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017 with Medical categories.
A popular entry-level guide into the use of R as a statistical programming and data management language for students, post-docs, and seasoned researchers now in a new revised edition, incorporating the updates in the R environment, and also adding guidance on the use of more complex statistical analyses and tools.
Introduction To Bioinformatics
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Author : Arthur M. Lesk
language : en
Publisher:
Release Date : 2019
Introduction To Bioinformatics written by Arthur M. Lesk and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019 with categories.
Statistical Methods In Bioinformatics
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Author : Warren J. Ewens
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-09
Statistical Methods In Bioinformatics written by Warren J. Ewens and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-09 with Medical categories.
There was a real need for a book that introduces statistics and probability as they apply to bioinformatics. This book presents an accessible introduction to elementary probability and statistics and describes the main statistical applications in the field.
Introduction To Bioinformatics
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Author : Arthur Lesk
language : en
Publisher:
Release Date : 2019-05
Introduction To Bioinformatics written by Arthur Lesk and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-05 with categories.
The ideal text for biology students encountering bioinformatics for the first time, Introduction to Bioinformatics describes how recent technological advances in the field can be used as a powerful set of tools for receiving and analyzing biological data.
Introduction To Bioinformatics With R
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Author : Edward Curry
language : en
Publisher: CRC Press
Release Date : 2020-11-02
Introduction To Bioinformatics With R written by Edward Curry and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-11-02 with Mathematics categories.
In biological research, the amount of data available to researchers has increased so much over recent years, it is becoming increasingly difficult to understand the current state of the art without some experience and understanding of data analytics and bioinformatics. An Introduction to Bioinformatics with R: A Practical Guide for Biologists leads the reader through the basics of computational analysis of data encountered in modern biological research. With no previous experience with statistics or programming required, readers will develop the ability to plan suitable analyses of biological datasets, and to use the R programming environment to perform these analyses. This is achieved through a series of case studies using R to answer research questions using molecular biology datasets. Broadly applicable statistical methods are explained, including linear and rank-based correlation, distance metrics and hierarchical clustering, hypothesis testing using linear regression, proportional hazards regression for survival data, and principal component analysis. These methods are then applied as appropriate throughout the case studies, illustrating how they can be used to answer research questions. Key Features: · Provides a practical course in computational data analysis suitable for students or researchers with no previous exposure to computer programming. · Describes in detail the theoretical basis for statistical analysis techniques used throughout the textbook, from basic principles · Presents walk-throughs of data analysis tasks using R and example datasets. All R commands are presented and explained in order to enable the reader to carry out these tasks themselves. · Uses outputs from a large range of molecular biology platforms including DNA methylation and genotyping microarrays; RNA-seq, genome sequencing, ChIP-seq and bisulphite sequencing; and high-throughput phenotypic screens. · Gives worked-out examples geared towards problems encountered in cancer research, which can also be applied across many areas of molecular biology and medical research. This book has been developed over years of training biological scientists and clinicians to analyse the large datasets available in their cancer research projects. It is appropriate for use as a textbook or as a practical book for biological scientists looking to gain bioinformatics skills.
Statistical Methods In Bioinformatics
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Author : Warren J. Ewens
language : en
Publisher: Springer Science & Business Media
Release Date : 2005-09-30
Statistical Methods In Bioinformatics written by Warren J. Ewens and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-09-30 with Science categories.
Advances in computers and biotechnology have had a profound impact on biomedical research, and as a result complex data sets can now be generated to address extremely complex biological questions. Correspondingly, advances in the statistical methods necessary to analyze such data are following closely behind the advances in data generation methods. The statistical methods required by bioinformatics present many new and difficult problems for the research community. This book provides an introduction to some of these new methods. The main biological topics treated include sequence analysis, BLAST, microarray analysis, gene finding, and the analysis of evolutionary processes. The main statistical techniques covered include hypothesis testing and estimation, Poisson processes, Markov models and Hidden Markov models, and multiple testing methods. The second edition features new chapters on microarray analysis and on statistical inference, including a discussion of ANOVA, and discussions of the statistical theory of motifs and methods based on the hypergeometric distribution. Much material has been clarified and reorganized. The book is written so as to appeal to biologists and computer scientists who wish to know more about the statistical methods of the field, as well as to trained statisticians who wish to become involved with bioinformatics. The earlier chapters introduce the concepts of probability and statistics at an elementary level, but with an emphasis on material relevant to later chapters and often not covered in standard introductory texts. Later chapters should be immediately accessible to the trained statistician. Sufficient mathematical background consists of introductory courses in calculus and linear algebra. The basic biological concepts that are used are explained, or can be understood from the context, and standard mathematical concepts are summarized in an Appendix. Problems are provided at the end of each chapter allowing the reader to develop aspects of the theory outlined in the main text. Warren J. Ewens holds the Christopher H. Brown Distinguished Professorship at the University of Pennsylvania. He is the author of two books, Population Genetics and Mathematical Population Genetics. He is a senior editor of Annals of Human Genetics and has served on the editorial boards of Theoretical Population Biology, GENETICS, Proceedings of the Royal Society B and SIAM Journal in Mathematical Biology. He is a fellow of the Royal Society and the Australian Academy of Science. Gregory R. Grant is a senior bioinformatics researcher in the University of Pennsylvania Computational Biology and Informatics Laboratory. He obtained his Ph.D. in number theory from the University of Maryland in 1995 and his Masters in Computer Science from the University of Pennsylvania in 1999. Comments on the first edition: "This book would be an ideal text for a postgraduate course...[and] is equally well suited to individual study.... I would recommend the book highly." (Biometrics) "Ewens and Grant have given us a very welcome introduction to what is behind those pretty [graphical user] interfaces." (Naturwissenschaften) "The authors do an excellent job of presenting the essence of the material without getting bogged down in mathematical details." (Journal American Statistical Association) "The authors have restructured classical material to a great extent and the new organization of the different topics is one of the outstanding services of the book." (Metrika)
The New Statistics With R
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Author : Andy Hector
language : en
Publisher: Oxford University Press, USA
Release Date : 2015
The New Statistics With R written by Andy Hector and has been published by Oxford University Press, USA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015 with Bioinformatics categories.
Statistical methods are a key tool for all scientists working with data, but learning the basic mathematical skills can be one of the most challenging components of a biologist's training. This accessible book provides a contemporary introduction to the classical techniques and modern extensions of linear model analysis: one of the most useful approaches in the analysis of scientific data in the life and environmental sciences. It emphasizes an estimation-based approach that accounts for recent criticisms of the over-use of probability values, and introduces alternative approaches using information criteria. Statistics are introduced through worked analyses performed in R, the free open source programming language for statistics and graphics, which is rapidly becoming the standard software in many areas of science and technology. These analyses use real data sets from ecology, evolutionary biology and environmental science, and the data sets and R scripts are available as support material. The book's structure and user friendly style stem from the author's 20 years of experience teaching statistics to life and environmental scientists at both the undergraduate and graduate levels. The New Statistics with R is suitable for senior undergraduate and graduate students, professional researchers, and practitioners in the fields of ecology, evolution, environmental studies, and computational biology.
Introduction To Bioinformatics
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Author : Stephen A. Krawetz
language : en
Publisher: Springer Science & Business Media
Release Date : 2003-01-31
Introduction To Bioinformatics written by Stephen A. Krawetz and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-01-31 with Science categories.
to Bioinformatics A Theoretical and Practical Approach Edited by Stephen A. Krawetz, PhD Wayne State University School of Medicine, Detroit MI and David D. Womble, PhD Wayne State University School of Medicine, Detroit, MI ~ Springer Science+ ~ Business Media, LLC © 2003 Springer Science+Business Media New York Originally published by Humana Press !ne. in 2003 Softcover reprint of the hardcover 1 st edition 2003 humanapress.com Ali rights reserved. No part of this book may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, electronic, mechanical, photocopying, microfilming, recording, or otherwise without written permission from the Publisher. Ali papers, comments, opinions, conclusions, or recommendations are those of the author(s), and do not necessarily reflect the views of the publisher. This publication is printed on acid-free paper. G) ANSI Z39.48-1984 (American Standards Institute) Permanence of Paper for Printed Library Materials. Production Editor: Mark J. Breaugh. Cover design by Patricia F. Cleary and Paul A. Thiessen. Cover illustration by Paul A. Thiessen, chemicalgraphics.com.