Introduction To Membrane Noise
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Introduction To Membrane Noise
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Author : Louis J. DeFelice
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Introduction To Membrane Noise written by Louis J. DeFelice and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Technology & Engineering categories.
I started working on membrane noise in 1967 with David Firth in the Department of Physiology at McGill University. I began writing this book in the summer of 1975 at Emory University under a grant from the National Library of Medicine. Part of the writing was also done at the Marine Biological Laboratory Library in Woods Hole and in the Library of the Stazione Zoologica in Naples. I wrote this book because in the intervening years membrane noise became a definable subdivision of membrane biophysics and seemed to deserve a uniform treatment in one volume. Not surprisingly, this turned out to be much more difficult than I had imagined and some areas of the subject that ought to be included have been left out, either for reasons of space or because of my own inability to keep up with all aspects of the field. This book is written for biologists interested in noise and for physicists and electrical engineers interested in biology. The first three chapters attempt to bring both groups to a common point of understanding of electronics and electrophysiology necessary to the study of noise and impedance in membranes. These chapters arose out of a course given over a period of six years to electrical engineers from the Georgia Institute of Technology and biologists from Emory University School of Medicine.
Thermodynamics Of Membrane Receptors And Channels
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Author : Meyer B. Jackson
language : en
Publisher: CRC Press
Release Date : 1992-11-18
Thermodynamics Of Membrane Receptors And Channels written by Meyer B. Jackson and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992-11-18 with Science categories.
Thermodynamics of Membrane Receptors and Channels synthesizes a wealth of new information regarding the biophysics of membrane proteins. New insights provided by molecular genetics, single channel recording, and high resolution structural techniques are discussed from a conceptual perspective. Basic theoretical topics are introduced, developed, and then extensively illustrated with recent results from the literature or data from the authors' own laboratories. Theoretical and experimental information is incorporated into in-depth discussions of ion permeation mechanisms, ion channel and receptor conformational changes, aggregate activity of complexes of lipids and proteins, and how coupling is achieved between different energy modes in the many transduction systems residing in biomembranes. Thermodynamics of Membrane Receptors and Channels will be valuable both as a learning aid and a reference for biophysicists, neuroscientists, cell biologists, physiologists, and other researchers investigating any aspects of biomembranes.
Squid As Experimental Animals
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Author : W.J., Jr. Adelman
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-06-29
Squid As Experimental Animals written by W.J., Jr. Adelman and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-29 with Science categories.
The predecessor to this book was A Guide to the Laboratory Use of the Squid Loligo pealei published by the Marine Biological Laboratory, Woods Hole, Massachusetts in 1974. The revision of this long out of date guide, with the approval of the Marine Biological Laboratory, is an attempt to introduce students and researchers to the cephalopods and particularly the squid as an object of biological research. Therefore, we have decided to expand on its original theme, which was to present important practical aspects for using the squid as experimental animals. There are twenty two chapters instead of the original eight. The material in the original eight chapters has been completely revised. Since more than one method can be used for accomplishing a given task, some duplication of methods was considered desirable in the various chapters. Thus, the methodology can be chosen which is best suited for each reader's requirements. Each subject also contains a mini-review which can serve as an introduction to the various topics. Thus, the volume is not just a laboratory manual, but can also be used as an introduction to squid biology. The book is intended for laboratory technicians, advanced undergraduate students, graduate students, researchers, and all others who want to learn the purpose, methods, and techniques of using squid as experimental animals. This is the reason why the name has been changed to its present title. Preceding the chapters is a list of many of the abbreviations, prefixes, and suffixes used in this volume.
Current Topics In Membranes And Transport
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Author :
language : en
Publisher: Academic Press
Release Date : 1991-01-18
Current Topics In Membranes And Transport written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1991-01-18 with Science categories.
Current Topics in Membranes and Transport
Stochastic Transport Processes In Discrete Biological Systems
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Author : Eckart Frehland
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-13
Stochastic Transport Processes In Discrete Biological Systems written by Eckart Frehland and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-13 with Science categories.
These notes are in part based on a course for advanced students in the applications of stochastic processes held in 1978 at the University of Konstanz. These notes contain the results of re cent studies on the stochastic description of ion transport through biological membranes. In particular, they serve as an introduction to an unified theory of fluctuations in complex biological transport systems. We emphasize that the subject of this volume is not to introduce the mathematics of stochastic processes but to present a field of theoretical biophysics in which stochastic methods are important. In the last years the study of membrane noise has become an important method in biophysics. Valuable information on the ion transport mechanisms in membranes can be obtained from noise analysis. A number of different processes such as the opening and closing of ion channels have been shown to be sources of the measured current or voltage fluctuations. Bio logical 'transport systems can be complex. For example, the transport process can be coupled to other processes such as chemical reactions and take place in discontinuous structures of molecular dimensions. Furthermore, since there are strong electric fields or high concentration gradients across biological membranes ion transport processes of biological relevance are mostly processes far from equilibrium. For these reasons the development of new theoretical concepts has been necessary. The concept of transport in discrete systems has turned out to be more appropriate than continuum models.
Single Channel Recording
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Author : Bert Sakmann
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-11
Single Channel Recording written by Bert Sakmann and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-11 with Science categories.
Single-channel recording has become a widely used tool for the study of ion permeation mechanisms in biological membranes. Whereas the technique might have been considered an "art" after its introduction in 1976, it developed into a relatively simple method after it became possible to obtain high-resistance (several gigaohm) membrane-pipette seals. In the summer of 1982, a course on the technique was held at the Ettore Majorana Center for Scientific Culture in Erice, Sicily. It brought together people from most of the laboratories involved in patch clamping at that time. During the course, it became apparent that the technique had reached a state of maturity. Repeatedly, the opinion was expressed that a detailed description of all the aspects of the technique including representative examples of results should be available. We therefore asked the course instructors, as well as several other colleagues, to provide chapters on selected topics in order to produce this volume. The different variants of patch clamping were described quite extensively in an article by Hamill, Marty, Neher, Sakmann, and Sigworth (Pflugers Archiv 391:85) in 1981. Rather than repeating this survey in an introductory chapter, we chose to reprint that article in the Appendix of this volume (by permission of Springer-Verlag). The methods section will, therefore, go straight into detailed aspects of the technol ogy.
Self Organized Biological Dynamics And Nonlinear Control
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Author : Jan Walleczek
language : en
Publisher: Cambridge University Press
Release Date : 2006-04-20
Self Organized Biological Dynamics And Nonlinear Control written by Jan Walleczek and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-04-20 with Science categories.
The growing impact of nonlinear science on biology and medicine is fundamentally changing our view of living organisms and disease processes. This book introduces the application to biomedicine of a broad range of interdisciplinary concepts from nonlinear dynamics, such as self-organization, complexity, coherence, stochastic resonance, fractals and chaos. It comprises 18 chapters written by leading figures in the field and covers experimental and theoretical research, as well as the emerging technological possibilities such as nonlinear control techniques for treating pathological biodynamics, including heart arrhythmias and epilepsy. This book will attract the interest of professionals and students from a wide range of disciplines, including physicists, chemists, biologists, sensory physiologists and medical researchers such as cardiologists, neurologists and biomedical engineers.
Mathematics For Neuroscientists
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Author : Fabrizio Gabbiani
language : en
Publisher: Academic Press
Release Date : 2010-09-16
Mathematics For Neuroscientists written by Fabrizio Gabbiani and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-09-16 with Medical categories.
Virtually all scientific problems in neuroscience require mathematical analysis, and all neuroscientists are increasingly required to have a significant understanding of mathematical methods. There is currently no comprehensive, integrated introductory book on the use of mathematics in neuroscience; existing books either concentrate solely on theoretical modeling or discuss mathematical concepts for the treatment of very specific problems. This book fills this need by systematically introducing mathematical and computational tools in precisely the contexts that first established their importance for neuroscience. All mathematical concepts will be introduced from the simple to complex using the most widely used computing environment, Matlab. This book will provide a grounded introduction to the fundamental concepts of mathematics, neuroscience and their combined use, thus providing the reader with a springboard to cutting-edge research topics and fostering a tighter integration of mathematics and neuroscience for future generations of students. - A very didactic and systematic introduction to mathematical concepts of importance for the analysis of data and the formulation of concepts based on experimental data in neuroscience - Provides introductions to linear algebra, ordinary and partial differential equations, Fourier transforms, probabilities and stochastic processes - Introduces numerical methods used to implement algorithms related to each mathematical concept - Illustrates numerical methods by applying them to specific topics in neuroscience, including Hodgkin-Huxley equations, probabilities to describe stochastic release, stochastic processes to describe noise in neurons, Fourier transforms to describe the receptive fields of visual neurons - Allows the mathematical novice to analyze their results in more sophisticated ways, and consider them in a broader theoretical framework
Bioengineering And Biophysical Aspects Of Electromagnetic Fields Fourth Edition
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Author : Ben Greenebaum
language : en
Publisher: CRC Press
Release Date : 2018-11-02
Bioengineering And Biophysical Aspects Of Electromagnetic Fields Fourth Edition written by Ben Greenebaum and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-11-02 with Technology & Engineering categories.
The two volumes of this new edition of the Handbook cover the basic biological, medical, physical, and electrical engineering principles. They also include experimental results concerning how electric and magnetic fields affect biological systems—both as potential hazards to health and potential tools for medical treatment and scientific research. They also include material on the relationship between the science and the regulatory processes concerning human exposure to the fields. Like its predecessors, this edition is intended to be useful as a reference book but also for introducing the reader to bioelectromagnetics or some of its aspects. FEATURES • New topics include coverage of electromagnetic effects in the terahertz region, effects on plants, and explicitly applying feedback concepts to the analysis of biological electromagnetic effects • Expanded coverage of electromagnetic brain stimulation, characterization and modeling of epithelial wounds, and recent lab experiments on at all frequencies • Section on background for setting standards and precautionary principle • Discussion of recent epidemiological, laboratory, and theoretical results; including: WHO IARC syntheses of epidemiological results on both high and low frequency fields, IITRI lab study of cancer in mice exposed to cell phone-like radiation, and other RF studies • All chapters updated by internationally acknowledged experts in the field
The Biophysical Basis Of Excitability
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Author : Hugo Gil Ferreira
language : en
Publisher: Cambridge University Press
Release Date : 1985-10-31
The Biophysical Basis Of Excitability written by Hugo Gil Ferreira and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1985-10-31 with Medical categories.
Defines the basic concepts from biology, mathematics, physics and chemistry that are needed to understand how excitable cells function. Applies them specifically to the study of membrane transport, artificial membranes, signal capturing and analysis in biological systems.