Investigation Of Human Mitochondrial Dna Abnormality In Colon Cancer
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Investigation Of Human Mitochondrial Dna Abnormality In Colon Cancer
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Author : Mansoureh Akouchekian
language : en
Publisher: Cuvillier Verlag
Release Date : 2008
Investigation Of Human Mitochondrial Dna Abnormality In Colon Cancer written by Mansoureh Akouchekian and has been published by Cuvillier Verlag this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with categories.
Mitochondrial Dna
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Author : Herve Seligmann
language : en
Publisher: BoD – Books on Demand
Release Date : 2018-10-31
Mitochondrial Dna written by Herve Seligmann and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-10-31 with Medical categories.
The very short genomes of mitochondria summarize the complexity of molecular biology and its interactions with cellular and whole organism biology. Studies of mitogenomes contribute to the understanding of molecular biology and evolution, and to health management. Despite or even due to their small sizes, mitogenomes continue to surprise us. Studies of mitogenomes reveal the details of molecular organization and its evolution under constraints for miniaturization.
Mitochondria And Cancer
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Author : Keshav Singh
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-04-05
Mitochondria And Cancer written by Keshav Singh and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-04-05 with Medical categories.
Nearly a century of scientific research has revealed that mitochondrial dysfunction is one of the most common and consistent phenotypes of cancer cells. A number of notable differences in the mitochondria of normal and cancer cells have been described. These include differences in mitochondrial metabolic activity, molecular composition of mitochondria and mtDNA sequence, as well as in alteration of nuclear genes encoding mitochondrial proteins. This book, Mitochondria and Cancer, edited by Keshav K. Singh and Leslie C. Costello, presents thorough analyses of mitochondrial dysfunction as one of the hallmarks of cancer, discusses the clinical implications of mitochondrial defects in cancer, and as unique cellular targets for novel and selective anti-cancer therapy.
Current Research On Clinical Cancer Diagnosis Therapy And Patient Care
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Author : Smithsonian Science Information Exchange. Current Cancer Research Project Analysis Center
language : en
Publisher:
Release Date : 1975
Current Research On Clinical Cancer Diagnosis Therapy And Patient Care written by Smithsonian Science Information Exchange. Current Cancer Research Project Analysis Center and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1975 with Cancer categories.
2775 references to research projects being conducted in the United States and elsewhere. Entries arranged under 11 topics, e.g., Cancer therapy, Supportive care of cancer patients, and Rehabilitation. Entries include title, researcher, address, contract number, summary, and supporting agency. Indexes by subjects, investigators, contractors, supporting agencies, and contractor numbers.
Research Awards Index
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Author :
language : en
Publisher:
Release Date : 1988
Research Awards Index written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1988 with Medicine categories.
Subject Index Of Current Extramural Research Administered By The National Cancer Institute
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Author :
language : en
Publisher:
Release Date : 1978
Subject Index Of Current Extramural Research Administered By The National Cancer Institute written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1978 with Cancer categories.
Assessing Genetic Risks
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Author : Institute of Medicine
language : en
Publisher: National Academies Press
Release Date : 1994-01-01
Assessing Genetic Risks written by Institute of Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994-01-01 with Medical categories.
Raising hopes for disease treatment and prevention, but also the specter of discrimination and "designer genes," genetic testing is potentially one of the most socially explosive developments of our time. This book presents a current assessment of this rapidly evolving field, offering principles for actions and research and recommendations on key issues in genetic testing and screening. Advantages of early genetic knowledge are balanced with issues associated with such knowledge: availability of treatment, privacy and discrimination, personal decision-making, public health objectives, cost, and more. Among the important issues covered: Quality control in genetic testing. Appropriate roles for public agencies, private health practitioners, and laboratories. Value-neutral education and counseling for persons considering testing. Use of test results in insurance, employment, and other settings.
Subject Index Of Current Extramural Research Administered By The National Cancer Institute
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Author : National Cancer Institute (U.S.)
language : en
Publisher:
Release Date : 1974
Subject Index Of Current Extramural Research Administered By The National Cancer Institute written by National Cancer Institute (U.S.) and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1974 with Cancer categories.
Cancer As A Metabolic Disease
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Author : Thomas Seyfried
language : en
Publisher: John Wiley & Sons
Release Date : 2012-05-18
Cancer As A Metabolic Disease written by Thomas Seyfried and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-05-18 with Science categories.
The book addresses controversies related to the origins of cancer and provides solutions to cancer management and prevention. It expands upon Otto Warburg's well-known theory that all cancer is a disease of energy metabolism. However, Warburg did not link his theory to the "hallmarks of cancer" and thus his theory was discredited. This book aims to provide evidence, through case studies, that cancer is primarily a metabolic disease requring metabolic solutions for its management and prevention. Support for this position is derived from critical assessment of current cancer theories. Brain cancer case studies are presented as a proof of principle for metabolic solutions to disease management, but similarities are drawn to other types of cancer, including breast and colon, due to the same cellular mutations that they demonstrate.
Studies On Retinal And Choroidal Disorders
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Author : Robert D. Stratton
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-02-17
Studies On Retinal And Choroidal Disorders written by Robert D. Stratton and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-02-17 with Science categories.
Studies on Retinal and Choroidal Disorders examines the role that oxidative and nitrosative stress plays in the complex physiology and pathophysiology of the retina and choroid. Both the basic science researcher and the clinical practitioner can use this book as a guide to the current understanding of retinal and choroidal cellular mechanisms involved in aging and disease. Beginning with a review of oxidative stress and inflammation in the pathoetiology of AMD and a review of the complement system in the retina, the book then takes a detailed look at oxidative stress in lipid metabolism and oxidized lipoproteins in the retina. It examines the anti-apoptotic activity of α-crystallins in the presence of glutathione, oxidative stress in the mitochondria and endoplasmic reticulum, the role of iron in retinal disease, the mechanisms of pathological VEGF expression, NAPDH oxidase mechanisms, and Hepatocyte Growth Factor in oxidative stress in the retina. A detailed look at the Ccl2-/-/Cx3cr1-/- mouse model of AMD follows. Then a detailed examination of the systemic changes in AMD is followed by a discussion of cerium oxide nanoparticle reduction of oxidative stress. Two chapters discuss progenitor cells in the cause and treatment of retinal diseases including AMD and diabetic retinopathy. Natural compounds in the prevention and treatment of retinal diseases are exhaustively presented, followed by a chapter on serotonin 5-HT1A receptor agonists in oxidative stress of the retina. The current anti-VEGF treatment strategies of neovascular AMD are then given. The volume continues with a detailed look at nitric oxide and inducible nitric oxide synthase in retinal vascular disease, an explanation of an in vivo technique of studying the effect of lipid hydroperoxides on circulating leucocytes in the retina, an excellent review of oxidative stress in retinopathy of prematurity, and a look at VEGF induced oxidative stress in the retinal ganglion cell. The book ends with a detail examination of the role of carotenoids in retinal health and disease. These 31 chapters summarize what is known about oxidative stress in retinal and choroidal disorders. All those involved with degenerative diseases of the eye will find Studies on Retinal and Choroidal Disorders to be illuminating and comprehensive.