Ion Flux In Pulmonary Vascular Control

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Ion Flux In Pulmonary Vascular Control

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Author : E Kenneth Weir
language : en
Publisher:
Release Date : 1993-11-30

Ion Flux In Pulmonary Vascular Control written by E Kenneth Weir and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993-11-30 with categories.

Membrane Receptors Channels And Transporters In Pulmonary Circulation

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Author : Jason X. -J. Yuan
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-03-10

Membrane Receptors Channels And Transporters In Pulmonary Circulation written by Jason X. -J. Yuan and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-03-10 with Medical categories.

Membrane Receptors, Channels and Transporters in Pulmonary Circulation is a proceeding of the 2008 Grover Conference (Lost Valley Ranch and Conference Center, Sedalia, Colorado; September 3-7, 2008), which provided a forum for experts in the fields of those receptors, channels and transporters that have been identified as playing key roles in the physiology and pathophysiology of the pulmonary circulation. The book rigorously addresses: i) recent advances in our knowledge of receptors, channels and transporters and their role in regulation of pulmonary vascular function; ii) how modulation of expression and function of receptors, channels and transporters and their interrelationships contribute to the pathogenesis of pulmonary vascular disease; and iii) the therapeutic opportunities that may be revealed by enhancing our understanding of this area. The overall goal was to explore the mechanisms by which specific receptors, channels and transporters contribute to pulmonary vascular function in both health and disease, and how this knowledge may lead to novel interventions in lung dysplasia, pulmonary edema, lung injury, and pulmonary and systemic hypertension to reduce and prevent death from lung disease. Membrane Receptors, Channels and Transporters in Pulmonary Circulation is divided into six parts. Part 1 (Ion Channels in the Pulmonary Vasculature: Basics and New Findings) is designated for basic knowledge and recent findings in the research field of ion channels in pulmonary circulation. There are five chapters in Part I discussing the function, expression, distribution and regulation of various ion channels present in pulmonary vascular smooth muscle cells and how these channels are integrated to regulate intracellular Ca2+ and cell functions. Part II (TRP Channels in the Pulmonary Vasculature: Basics and New Findings) is composed of five chapters that are exclusively designed to discuss the role of a recently identified family of cation channels, transient receptor potential (TRP) channels, in the regulation of pulmonary vascular tone and arterial structure. Part III (Pathogenic Role of Ion Channels in Pulmonary Vascular Disease) includes four chapters that discuss how abnormal function and expression of various ion channels contribute to changes in cell functions and the development of pulmonary hypertension. Part IV (Receptors and Signaling Cascades in Pulmonary Arterial Hypertension) consists of five chapters devoted to the role of bone morphogenetic protein receptors, Notch receptors, serotonin receptors, Rho kinase and vascular endothelial growth factor receptors in the development of pulmonary arterial hypertension. Part V (Receptors and Transporters: Role in Cell Function and Hypoxic Pulmonary Vasoconstriction) includes four chapters designed to illustrate the potential mechanisms involved in oxygen sensing and hypoxia-induced pulmonary vasoconstriction and hypertension. Part VI (Targeting Ion Channels and Membrane Receptors in Developing Novel Therapeutic Approaches for Pulmonary Vascular Disease) consists five chapters which discuss the translational research involving on membrane receptors, channels and transporters, including their potential as novel drug targets. We hope that Membrane Receptors, Channels and Transporters in Pulmonary Circulation will allow readers to foster new concepts and new collaborations and cooperations among investigators so as to further understand the role of receptors, channels and transporters in lung pathophysiology. The ultimate goal is to identify new mechanisms of disease, as well as new therapeutic targets for pulmonary vascular diseases. An additional outcome should be enhanced understanding of the role of these entities in systemic vascular pathophysiology, since the conference will include researchers and clinicians with interests in both pulmonary and systemic circulations.

Biomedical Index To Phs Supported Research Pt A Subject Access A H

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Author :
language : en
Publisher:
Release Date : 1992

Biomedical Index To Phs Supported Research Pt A Subject Access A H written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992 with Medicine categories.

Cardiovascular Catheterization And Intervention

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Author : Debabrata Mukherjee
language : en
Publisher: CRC Press
Release Date : 2017-09-11

Cardiovascular Catheterization And Intervention written by Debabrata Mukherjee and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-09-11 with Medical categories.

Interventional cardiology refers to the catheter-based treatment of cardiovascular diseases and is one of the fastest growing fields in medicine. This updated text addresses recent advances in structural heart interventions, in particular aortic and mitral valve procedures. The advent of newer technologies presents both opportunities and challenges for the cardiologist to treat patients optimally. Interventional cardiologists are now at the forefront of peripheral and structural heart interventions. This new edition focuses on tailoring treatment to individual patients, taking into account specific risk factors and comorbidities, and appropriate use of devices. This second edition also provides useful tools, such as treatment algorithms, evidence tables, charts, tables, and illustrations to enhance the value of this volume as a practical reference tool. The online edition also includes several "how-to" videos.

Cell Signaling In Vascular Inflammation

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Author : Jahar Bhattacharya
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-11-15

Cell Signaling In Vascular Inflammation written by Jahar Bhattacharya and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-11-15 with Medical categories.

A comprehensive survey by leading basic and clinical researchers of the signal transduction mechanisms responsible for lung inflammation, including vascular hyperpermeability, white cell accumulation, and vascular remodeling. The authors cut across disciplines to bring together a broad-based presentation of inflammatory challenge, both in the initial phases of the inflammatory response, as well as in the more prolonged phase of genomic involvement. The book illuminates not only the processes of lung inflammation, but also the potential for developing new therapeutic strategies to combat inflammatory lung disease.

Oxygen Sensing

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Author : Sukhamay Lahiri
language : en
Publisher: Springer Science & Business Media
Release Date : 2006-03-06

Oxygen Sensing written by Sukhamay Lahiri and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-03-06 with Medical categories.

Proceedings of the XIVth International Symposium on Arterial Chemoreception, held June 24-28, 1999, in Philadelphia, Pennsylvania. This volume, containing the proceedings of the fourteenth biannual ISAC meeting presents a new departure from their traditional focus on arterial chemoreceptors and their functions, in the expansion to include the study and discussion of oxygen sensing in other tissues and cells, and the genes involved. Bringing together scientists from cellular and systemic boundaries of physiology, working at the interface of cellular and molecular biology, this book, containing new physiological and biochemical perspectives.

Pharmacotherapy Of Pulmonary Hypertension

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Author : Marc Humbert
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-10-04

Pharmacotherapy Of Pulmonary Hypertension written by Marc Humbert and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-04 with Medical categories.

This volume focuses on current evidence-based pharmacological treatments of various forms of pulmonary hypertension and provides a comprehensive review of the latest developments in this area. The first part of the book covers the definition, classification, pathophysiology, pathology, biomarkers and animal models of the disease, thus laying the conceptual basis for what follows. The middle section provides an overview of the established therapies, such as calcium channel blockers, prostanoids, endothelin receptor antagonists, phosphodiesterase-5 inhibitors and inhaled nitric oxide. The last section explores novel pathways and emerging therapeutic approaches including soluble guanylate cyclase stimulators, Rho-kinase inhibitors, inhibitors of serotonin receptors and transporters, peptide growth factors, vasoactive peptides, modulators of redox equilibrium and cyclic nucleotide homeostasis, as well as immunosuppressive and anti-proliferative agents. Particular attention is given to the clinical applications of these experimental therapies, that are on the horizon. The book thus spans the continuum from basic science to clinical applications.

Biochemistry And Molecular Biology Compendium

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Author : Roger L. Lundblad
language : en
Publisher: CRC Press
Release Date : 2019-11-11

Biochemistry And Molecular Biology Compendium written by Roger L. Lundblad and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-11 with Medical categories.

This book is an accessible resource offering practical information not found in more database-oriented resources. The first chapter lists acronyms with definitions, and a glossary of terms and subjects used in biochemistry, molecular biology, biotechnology, proteomics, genomics, and systems biology. There follows chapters on chemicals employed in biochemistry and molecular biology, complete with properties and structure drawings. Researchers will find this book to be a valuable tool that will save them time, as well as provide essential links to the roots of their science. Key selling features: Contains an extensive list of commonly used acronyms with definitions Offers a highly readable glossary for systems and techniques Provides comprehensive information for the validation of biotechnology assays and manufacturing processes Includes a list of Log P values, water solubility, and molecular weight for selected chemicals Gives a detailed listing of protease inhibitors and cocktails, as well as a list of buffers

Echocardiography In Practice

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Author : Susan E. Wiegers
language : en
Publisher: CRC Press
Release Date : 2000-11-23

Echocardiography In Practice written by Susan E. Wiegers and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-11-23 with Medical categories.

A short clinical text introduces each of the 150 cases. The echocardiograms are demonstrated by 2-5 high-quality images accompanied by legends describing the views and salient details. These include two-dimesional images, M-mode tracings, spectral Doppler and colour Doppler echocardiograms. A short commentary follows in which the relevance of the echocardiographic findings is discussed. The text will also be useful for those taking the echocardiography examinations of the American Society of Echocardiography (ASE).

Resource Utilization And Development

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Author : Shri Kamal Sharma
language : en
Publisher: Northern Book Centre
Release Date : 1992

Resource Utilization And Development written by Shri Kamal Sharma and has been published by Northern Book Centre this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992 with Conservation of natural resources categories.

The relationship between resources and development is the pivot around which the present study revolves. Focussing on the process of resource creation and utilization it emphasizes the need of equitable development integrating local needs, resources, people and functions. The resource exploitation and their utilization are two independent economic activities influenced by different algorithms and usually have manifested in core-periphery relationship. Reviews the persistent problems of economic development in perspective of exploitation of natural resources with the objective to provide some clues for occurrence and persistence of regional disparities and for suggesting a development model synchronising both the resource management and environmental protection.