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Ionotropic Glutamate Receptor Technologies


Ionotropic Glutamate Receptor Technologies
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Ionotropic Glutamate Receptor Technologies


Ionotropic Glutamate Receptor Technologies
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Author : Gabriela K. Popescu
language : en
Publisher: Humana Press
Release Date : 2016-08-23

Ionotropic Glutamate Receptor Technologies written by Gabriela K. Popescu and has been published by Humana Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-08-23 with Medical categories.


This detailed volume explores key technologies that are used currently to investigate iGluR structure, function and physiology. Chapters in this book cover methods to help illuminate the assembly, trafficking, molecular composition and subcellular location of iGluRs; approaches used to understand the atomic organization of iGluRs; and techniques to monitor receptor activity in real time. Written in the popular Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your own laboratory. Concise and easy-to-use, Ionotropic Glutamate Receptor Technologies aims to facilitate the implementation of specific methods to iGluR investigations.



Metabotropic Glutamate Receptor Technologies


Metabotropic Glutamate Receptor Technologies
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Author : M Foster Olive
language : en
Publisher: Humana
Release Date : 2021-02-12

Metabotropic Glutamate Receptor Technologies written by M Foster Olive and has been published by Humana this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-02-12 with Medical categories.


This volume highlights various techniques used to study multiple aspects of mGlu receptor function. Chapters in this book cover topics such as modern approaches for the development and screening of allosteric modulators; fluctuations in intracellular calcium induced by mGlu receptor activation; dopamine-glutamate interactions in the central nervous system; methods for assessing mGlu receptor localization; and common techniques for evaluating mGlu modulation in behavior in rodents, including stress and alcohol drinking. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Cutting-edge and practical, Metabotropic Glutamate Receptor Technologies provides researchers with a starting point to address important questions regarding mGlu and its importance. Researchers working in the fields of neuroscience and physiology of multiple peripheral systems will find this volume most useful.



The Ionotropic Glutamate Receptors


The Ionotropic Glutamate Receptors
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Author : Daniel Monaghan
language : en
Publisher:
Release Date : 1996-10-01

The Ionotropic Glutamate Receptors written by Daniel Monaghan and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996-10-01 with categories.




Glutamate Related Biomarkers In Drug Development For Disorders Of The Nervous System


Glutamate Related Biomarkers In Drug Development For Disorders Of The Nervous System
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Author : Institute of Medicine
language : en
Publisher: National Academies Press
Release Date : 2011-08-05

Glutamate Related Biomarkers In Drug Development For Disorders Of The Nervous System written by Institute of Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-08-05 with Medical categories.


Glutamate is the most pervasive neurotransmitter in the central nervous system (CNS). Despite this fact, no validated biological markers, or biomarkers, currently exist for measuring glutamate pathology in CNS disorders or injuries. Glutamate dysfunction has been associated with an extensive range of nervous system diseases and disorders. Problems with how the neurotransmitter glutamate functions in the brain have been linked to a wide variety of disorders, including schizophrenia, Alzheimer's, substance abuse, and traumatic brain injury. These conditions are widespread, affecting a large portion of the United States population, and remain difficult to treat. Efforts to understand, treat, and prevent glutamate-related disorders can be aided by the identification of valid biomarkers. The Institute of Medicine's Forum on Neuroscience and Nervous System Disorders held a workshop on June 21-22, 2010, to explore ways to accelerate the development, validation, and implementation of such biomarkers. Glutamate-Related Biomarkers in Drug Development for Disorders of the Nervous System: Workshop Summary investigates promising current and emerging technologies, and outlines strategies to procure resources and tools to advance drug development for associated nervous system disorders. Moreover, this report highlights presentations by expert panelists, and the open panel discussions that occurred during the workshop.



Binding And Gating Properties Of The Kainate Ionotropic Glutamate Receptor


Binding And Gating Properties Of The Kainate Ionotropic Glutamate Receptor
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Author : Anne-Marie Louise Fay
language : en
Publisher:
Release Date : 2009

Binding And Gating Properties Of The Kainate Ionotropic Glutamate Receptor written by Anne-Marie Louise Fay and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009 with categories.




The Ionotropic Glutamate Receptors


The Ionotropic Glutamate Receptors
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Author : Daniel Monaghan
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

The Ionotropic Glutamate Receptors written by Daniel Monaghan and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.


The Ionotropic Glutamate Receptors provides the first detailed survey of the biochemical, physiological, and pharmacological properties of recombinant ionotropic glutamate receptors. The distinguished contributors show how the molecular characteristics of these receptors account for many of the properties of native ionotropic glutamate receptors. They also examine in detail the properties of glutamate receptor subunits, including receptor modulation by phosphorylation and the anatomical localization of specific glutamate receptor subunits as determined by in situ hybridization and immunochemistry. The Ionotropic Glutamate Receptors conveys the first clear insights into the molecular bases underlying the wealth of pharmacological and physiological data on these receptors.



The Glutamate Receptors


The Glutamate Receptors
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Author : Robert W. Gereau
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-02-23

The Glutamate Receptors written by Robert W. Gereau and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-02-23 with Medical categories.


This insightful and comprehensive book covers nearly every aspect of glutamate receptor structure and function for the working researcher and student. It condenses two previous landmark volumes into one easily accessible volume, and covers the extraordinary research and significant developments in the decade since the previous books were published. This includes the central role glutamate receptors play in neurotransmission.



Biology Of The Nmda Receptor


Biology Of The Nmda Receptor
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Author : Antonius M. VanDongen
language : en
Publisher: CRC Press
Release Date : 2008-10-29

Biology Of The Nmda Receptor written by Antonius M. VanDongen and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-10-29 with Medical categories.


The NMDA receptor plays a critical role in the development of the central nervous system and in adult neuroplasticity, learning, and memory. Therefore, it is not surprising that this receptor has been widely studied. However, despite the importance of rhythms for the sustenance of life, this aspect of NMDAR function remains poorly studied. Written



Gaba And Glutamate


Gaba And Glutamate
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Author : Janko Samardzic
language : en
Publisher: BoD – Books on Demand
Release Date : 2018-03-21

Gaba And Glutamate written by Janko Samardzic and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-03-21 with Medical categories.


This book collates the contributions of a selected number of neuroscientists that are interested in the molecular, preclinical, and clinical aspects of neurotransmission research. The seven chapters in this book address the latest research/review data related to GABA/glutamate system's organization and function, the structure of receptors, subtypes and their ligands, as well as the translational approach and clinical implications. The book offers readers a rich collection of data regarding current and future applications of GABA and glutamate neurotransmission, including promising research strategies and potential clinical benefits.



Marine Toxins As Research Tools


Marine Toxins As Research Tools
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Author : Nobuhiro Fusetani
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-01-31

Marine Toxins As Research Tools written by Nobuhiro Fusetani and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-01-31 with Science categories.


Marine organisms produce a wide array of toxins, many of which are not only structurally unusual, but also show potent and interesting modes of action. Since the discovery of tetrodotoxin, a pufferfish toxin, as a potent and selective blocker of Na+ channels in 1964, it has been widely used as a research tool in pharmacological and physiological research. This has led to the identification of a number of important biological functions for Na+ channels. In recent years, much biological research has been carried out at molecular and cellular levels, and therefore selective inhibitors of enzymes and selective antagonist/agonists of receptors and channels have become increasingly important research tools. Accordingly, interest in using such compounds as reagents has increased. Marine toxins are some of the most popular research tools and have already contributed much to our understanding of biological processes and disease mechanisms.